Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | ARL6IP6 | Human | 1,2-dimethylhydrazine | multiple interactions | ISO | Arl6ip6 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ARL6IP6 mRNA | CTD | PMID:22206623 | ARL6IP6 | Human | 1,2-dimethylhydrazine | affects expression | ISO | Arl6ip6 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of ARL6IP6 mRNA | CTD | PMID:22206623 | ARL6IP6 | Human | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of ARL6IP6 mRNA | CTD | PMID:31614463 | ARL6IP6 | Human | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | Arl6ip6 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:31826744 | ARL6IP6 | Human | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Arl6ip6 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARL6IP6 mRNA | CTD | PMID:21570461 | ARL6IP6 | Human | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARL6IP6 mRNA | CTD | PMID:22574217 | ARL6IP6 | Human | 3H-1,2-dithiole-3-thione | decreases expression | ISO | Arl6ip6 (Rattus norvegicus) | 6480464 | 1 and 2-dithiol-3-thione results in decreased expression of ARL6IP6 mRNA | CTD | PMID:19162173 | ARL6IP6 | Human | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of ARL6IP6 gene | CTD | PMID:27153756 | ARL6IP6 | Human | arsenite(3-) | multiple interactions | EXP | | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to ARL6IP6 mRNA] | CTD | PMID:32406909 | ARL6IP6 | Human | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of ARL6IP6 mRNA | CTD | PMID:21632981 | ARL6IP6 | Human | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ARL6IP6 mRNA | CTD | PMID:32234424 | ARL6IP6 | Human | benzo[a]pyrene | decreases expression | ISO | Arl6ip6 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ARL6IP6 mRNA | CTD | PMID:15034205 | ARL6IP6 | Human | benzo[a]pyrene | multiple interactions | ISO | Arl6ip6 (Mus musculus) | 6480464 | AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of ARL6IP6 mRNA] | CTD | PMID:15034205 | ARL6IP6 | Human | bisphenol A | affects expression | ISO | Arl6ip6 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of ARL6IP6 mRNA | CTD | PMID:25181051 | ARL6IP6 | Human | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of ARL6IP6 gene | CTD | PMID:31601247 | ARL6IP6 | Human | bisphenol A | increases expression | ISO | Arl6ip6 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of ARL6IP6 mRNA | CTD | PMID:33296240 | ARL6IP6 | Human | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ARL6IP6 mRNA | CTD | PMID:29275510 | ARL6IP6 | Human | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of ARL6IP6 mRNA | CTD | PMID:38568856 | ARL6IP6 | Human | caffeine | increases phosphorylation | EXP | | 6480464 | Caffeine results in increased phosphorylation of ARL6IP6 protein | CTD | PMID:35688186 | ARL6IP6 | Human | calcitriol | multiple interactions | EXP | | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of ARL6IP6 mRNA | CTD | PMID:21592394 | ARL6IP6 | Human | calcitriol | decreases expression | EXP | | 6480464 | Calcitriol results in decreased expression of ARL6IP6 mRNA | CTD | PMID:21592394 | ARL6IP6 | Human | carbon nanotube | decreases expression | ISO | Arl6ip6 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | ARL6IP6 | Human | copper(II) sulfate | decreases expression | EXP | | 6480464 | Copper Sulfate results in decreased expression of ARL6IP6 mRNA | CTD | PMID:19549813 | ARL6IP6 | Human | coumarin | decreases phosphorylation | EXP | | 6480464 | coumarin results in decreased phosphorylation of ARL6IP6 protein | CTD | PMID:35688186 | ARL6IP6 | Human | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of ARL6IP6 mRNA | CTD | PMID:20106945 | ARL6IP6 | Human | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of ARL6IP6 mRNA | CTD | PMID:25562108 | ARL6IP6 | Human | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARL6IP6 mRNA | CTD | PMID:27188386 | ARL6IP6 | Human | folic acid | multiple interactions | ISO | Arl6ip6 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ARL6IP6 mRNA | CTD | PMID:22206623 | ARL6IP6 | Human | folic acid | increases expression | ISO | Arl6ip6 (Mus musculus) | 6480464 | Folic Acid results in increased expression of ARL6IP6 mRNA | CTD | PMID:25629700 | ARL6IP6 | Human | formaldehyde | decreases expression | EXP | | 6480464 | Formaldehyde results in decreased expression of ARL6IP6 mRNA | CTD | PMID:23649840 | ARL6IP6 | Human | FR900359 | decreases phosphorylation | EXP | | 6480464 | FR900359 results in decreased phosphorylation of ARL6IP6 protein | CTD | PMID:37730182 | ARL6IP6 | Human | fulvestrant | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of ARL6IP6 gene | CTD | PMID:31601247 | ARL6IP6 | Human | ketamine | decreases expression | ISO | Arl6ip6 (Rattus norvegicus) | 6480464 | Ketamine results in decreased expression of ARL6IP6 mRNA | CTD | PMID:20080153 | ARL6IP6 | Human | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ARL6IP6 mRNA | CTD | PMID:21420995 | ARL6IP6 | Human | paracetamol | increases expression | ISO | Arl6ip6 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of ARL6IP6 mRNA | CTD | PMID:33387578 | ARL6IP6 | Human | perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of ARL6IP6 protein | CTD | PMID:26879310 | ARL6IP6 | Human | phenylmercury acetate | decreases expression | EXP | | 6480464 | Phenylmercuric Acetate results in decreased expression of ARL6IP6 mRNA | CTD | PMID:26272509 | ARL6IP6 | Human | phenylmercury acetate | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARL6IP6 mRNA | CTD | PMID:27188386 | ARL6IP6 | Human | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARL6IP6 mRNA | CTD | PMID:27188386 | ARL6IP6 | Human | sodium arsenite | multiple interactions | EXP | | 6480464 | sodium arsenite results in decreased expression of and affects the splicing of ARL6IP6 mRNA | CTD | PMID:25879800 | ARL6IP6 | Human | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of ARL6IP6 mRNA | CTD | PMID:38568856 | ARL6IP6 | Human | testosterone | multiple interactions | EXP | | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of ARL6IP6 mRNA | CTD | PMID:21592394 | ARL6IP6 | Human | testosterone | decreases expression | EXP | | 6480464 | Testosterone results in decreased expression of ARL6IP6 mRNA | CTD | PMID:21592394 | ARL6IP6 | Human | thioacetamide | increases expression | ISO | Arl6ip6 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of ARL6IP6 mRNA | CTD | PMID:34492290 | ARL6IP6 | Human | titanium dioxide | decreases methylation | ISO | Arl6ip6 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of ARL6IP6 gene and titanium dioxide results in decreased methylation of ARL6IP6 promoter alternative form | CTD | PMID:35295148 | ARL6IP6 | Human | trichloroethene | decreases methylation | ISO | Arl6ip6 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased methylation of ARL6IP6 gene | CTD | PMID:27618143 | ARL6IP6 | Human | triphenyl phosphate | affects expression | EXP | | 6480464 | triphenyl phosphate affects the expression of ARL6IP6 mRNA | CTD | PMID:37042841 | ARL6IP6 | Human | tungsten | increases expression | ISO | Arl6ip6 (Mus musculus) | 6480464 | Tungsten results in increased expression of ARL6IP6 mRNA | CTD | PMID:30912803 | ARL6IP6 | Human | urethane | increases expression | EXP | | 6480464 | Urethane results in increased expression of ARL6IP6 mRNA | CTD | PMID:28818685 | ARL6IP6 | Human | valproic acid | decreases methylation | EXP | | 6480464 | Valproic Acid results in decreased methylation of ARL6IP6 gene | CTD | PMID:29154799 | ARL6IP6 | Human | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of ARL6IP6 mRNA | CTD | PMID:23179753 | |