PGLYRP2 (peptidoglycan recognition protein 2) - Rat Genome Database

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Gene: PGLYRP2 (peptidoglycan recognition protein 2) Homo sapiens
Analyze
Symbol: PGLYRP2
Name: peptidoglycan recognition protein 2
RGD ID: 1346354
HGNC Page HGNC:30013
Description: Enables N-acetylmuramoyl-L-alanine amidase activity; peptidoglycan binding activity; and peptidoglycan immune receptor activity. Involved in defense response to Gram-positive bacterium and detection of bacterium. Located in extracellular exosome.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: HMFT0141; N-acetylmuramoyl-L-alanine amidase; peptidoglycan recognition protein L; peptidoglycan recognition protein long; peptidoglycan recognition protein-like; PGLYRPL; PGRP-L; PGRPL; tagL; tagL-alpha; tagl-beta; TAGL-like
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381915,468,645 - 15,479,501 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1915,468,645 - 15,498,956 (-)EnsemblGRCh38hg38GRCh38
GRCh371915,579,456 - 15,590,312 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361915,440,456 - 15,451,315 (-)NCBINCBI36Build 36hg18NCBI36
Build 341915,440,462 - 15,451,312NCBI
Celera1915,476,268 - 15,487,143 (-)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1915,147,207 - 15,158,066 (-)NCBIHuRef
CHM1_11915,579,067 - 15,589,927 (-)NCBICHM1_1
T2T-CHM13v2.01915,593,641 - 15,604,523 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7663175   PMID:11441184   PMID:11461926   PMID:11752456   PMID:12477932   PMID:12669421   PMID:12754519   PMID:12975309   PMID:14506276   PMID:14702039   PMID:15221005   PMID:15340057  
PMID:15340161   PMID:16054449   PMID:16239516   PMID:16335952   PMID:16344560   PMID:16714290   PMID:17975119   PMID:18649358   PMID:19023099   PMID:20237496   PMID:21873635   PMID:23376485  
PMID:23533145   PMID:24838182   PMID:25544563   PMID:26039076   PMID:29914927   PMID:31479523   PMID:32296183   PMID:32967043   PMID:33427621   PMID:34461924   PMID:35218888  


Genomics

Comparative Map Data
PGLYRP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381915,468,645 - 15,479,501 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1915,468,645 - 15,498,956 (-)EnsemblGRCh38hg38GRCh38
GRCh371915,579,456 - 15,590,312 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361915,440,456 - 15,451,315 (-)NCBINCBI36Build 36hg18NCBI36
Build 341915,440,462 - 15,451,312NCBI
Celera1915,476,268 - 15,487,143 (-)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1915,147,207 - 15,158,066 (-)NCBIHuRef
CHM1_11915,579,067 - 15,589,927 (-)NCBICHM1_1
T2T-CHM13v2.01915,593,641 - 15,604,523 (-)NCBIT2T-CHM13v2.0
Pglyrp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391732,631,433 - 32,643,157 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1732,631,433 - 32,643,141 (-)EnsemblGRCm39 Ensembl
GRCm381732,412,459 - 32,424,219 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1732,412,459 - 32,424,167 (-)EnsemblGRCm38mm10GRCm38
MGSCv371732,550,045 - 32,557,920 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361732,550,306 - 32,561,112 (-)NCBIMGSCv36mm8
Celera1733,325,622 - 33,333,482 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.56NCBI
Pglyrp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8712,069,414 - 12,082,437 (-)NCBIGRCr8
mRatBN7.2711,418,674 - 11,432,162 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl711,418,880 - 11,427,773 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx714,237,304 - 14,246,286 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0716,114,726 - 16,123,712 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,986,312 - 13,995,267 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0714,426,481 - 14,435,987 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl714,429,701 - 14,435,967 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0714,580,379 - 14,588,764 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,995,858 - 12,996,949 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera79,530,143 - 9,537,285 (-)NCBICelera
Cytogenetic Map7q11NCBI
Pglyrp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554957,785,193 - 7,796,210 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554957,785,398 - 7,792,158 (+)NCBIChiLan1.0ChiLan1.0
PGLYRP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22020,378,029 - 20,396,483 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11919,380,830 - 19,399,218 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,999,893 - 15,012,376 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11915,986,083 - 15,997,726 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1915,986,090 - 15,997,726 (-)Ensemblpanpan1.1panPan2
PGLYRP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12046,724,906 - 46,730,227 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2046,726,224 - 46,730,321 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2046,572,665 - 46,577,974 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02047,211,739 - 47,217,048 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2047,210,950 - 47,217,128 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12046,446,615 - 46,451,923 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02046,863,271 - 46,868,579 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02047,136,764 - 47,142,073 (+)NCBIUU_Cfam_GSD_1.0
Pglyrp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118205,489,000 - 205,495,525 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365965,038,452 - 5,044,569 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365965,038,452 - 5,043,172 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGLYRP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl262,134,533 - 62,140,184 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1262,135,578 - 62,140,180 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2261,567,649 - 61,572,250 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PGLYRP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1614,072,310 - 14,084,014 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl614,072,423 - 14,082,798 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660745,424,409 - 5,435,504 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pglyrp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249012,554,048 - 2,561,826 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249012,554,303 - 2,562,436 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PGLYRP2
37 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19p13.12-q11(chr19:13974677-27839676)x3 copy number gain See cases [RCV000052912] Chr19:13974677..27839676 [GRCh38]
Chr19:14085489..28330584 [GRCh37]
Chr19:13946489..33022424 [NCBI36]
Chr19:19p13.12-q11
pathogenic
GRCh38/hg38 19p13.12(chr19:15227306-15496644)x3 copy number gain See cases [RCV000054146] Chr19:15227306..15496644 [GRCh38]
Chr19:15338117..15607455 [GRCh37]
Chr19:15199117..15468455 [NCBI36]
Chr19:19p13.12
uncertain significance
NM_052890.3(PGLYRP2):c.606C>T (p.Ser202=) single nucleotide variant Malignant melanoma [RCV000071966] Chr19:15476064 [GRCh38]
Chr19:15586875 [GRCh37]
Chr19:15447875 [NCBI36]
Chr19:19p13.12
not provided
GRCh38/hg38 19p13.2-q13.31(chr19:11227942-44626354)x3 copy number gain See cases [RCV000133888] Chr19:11227942..44626354 [GRCh38]
Chr19:11338618..45129651 [GRCh37]
Chr19:11199618..49821491 [NCBI36]
Chr19:19p13.2-q13.31
pathogenic
GRCh38/hg38 19p13.12-13.11(chr19:14154962-16914313)x1 copy number loss See cases [RCV000134176] Chr19:14154962..16914313 [GRCh38]
Chr19:14265774..17025123 [GRCh37]
Chr19:14126774..16886123 [NCBI36]
Chr19:19p13.12-13.11
pathogenic
GRCh38/hg38 19p13.12-12(chr19:15133594-24193591)x3 copy number gain See cases [RCV000136696] Chr19:15133594..24193591 [GRCh38]
Chr19:15244405..24376393 [GRCh37]
Chr19:15105405..24168233 [NCBI36]
Chr19:19p13.12-12
pathogenic|likely pathogenic
GRCh37/hg19 19p13.12-13.11(chr19:14124666-16431349)x1 copy number loss See cases [RCV000448818] Chr19:14124666..16431349 [GRCh37]
Chr19:19p13.12-13.11
pathogenic
GRCh37/hg19 19p13.12-13.11(chr19:14883158-16788770)x1 copy number loss See cases [RCV000511367] Chr19:14883158..16788770 [GRCh37]
Chr19:19p13.12-13.11
pathogenic
NM_052890.4(PGLYRP2):c.325G>T (p.Gly109Trp) single nucleotide variant not specified [RCV004283964] Chr19:15476345 [GRCh38]
Chr19:15587156 [GRCh37]
Chr19:19p13.12
uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19p13.12(chr19:15246479-15683078)x3 copy number gain not provided [RCV000740052] Chr19:15246479..15683078 [GRCh37]
Chr19:19p13.12
benign
GRCh37/hg19 19p13.12(chr19:15278099-15710360)x3 copy number gain not provided [RCV000740056] Chr19:15278099..15710360 [GRCh37]
Chr19:19p13.12
benign
GRCh37/hg19 19p13.12(chr19:15338105-15668026)x1 copy number loss not provided [RCV000847812] Chr19:15338105..15668026 [GRCh37]
Chr19:19p13.12
uncertain significance
GRCh37/hg19 19p13.12(chr19:14368330-15712368)x1 copy number loss not provided [RCV001007034] Chr19:14368330..15712368 [GRCh37]
Chr19:19p13.12
pathogenic
NM_052890.4(PGLYRP2):c.493G>A (p.Val165Ile) single nucleotide variant not specified [RCV004315805] Chr19:15476177 [GRCh38]
Chr19:15586988 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.701G>T (p.Gly234Val) single nucleotide variant not provided [RCV000894148] Chr19:15475969 [GRCh38]
Chr19:15586780 [GRCh37]
Chr19:19p13.12
benign
GRCh37/hg19 19p13.12-12(chr19:14286624-20956753)x3 copy number gain not provided [RCV001259370] Chr19:14286624..20956753 [GRCh37]
Chr19:19p13.12-12
pathogenic
GRCh37/hg19 19p13.12(chr19:15184922-15582812) copy number gain not specified [RCV002052676] Chr19:15184922..15582812 [GRCh37]
Chr19:19p13.12
uncertain significance
GRCh37/hg19 19p13.12-13.11(chr19:14124666-16431349) copy number loss not specified [RCV002052675] Chr19:14124666..16431349 [GRCh37]
Chr19:19p13.12-13.11
pathogenic
NC_000019.9:g.(?_14847048)_(17394124_?)del deletion not provided [RCV003116664] Chr19:14847048..17394124 [GRCh37]
Chr19:19p13.12-13.11
uncertain significance
NM_052890.4(PGLYRP2):c.698G>C (p.Arg233Pro) single nucleotide variant not specified [RCV004139333] Chr19:15475972 [GRCh38]
Chr19:15586783 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.1492A>G (p.Thr498Ala) single nucleotide variant not specified [RCV004204030] Chr19:15469781 [GRCh38]
Chr19:15580592 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.1447G>A (p.Val483Met) single nucleotide variant not specified [RCV004169888] Chr19:15469826 [GRCh38]
Chr19:15580637 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.1678A>G (p.Arg560Gly) single nucleotide variant not specified [RCV004104511] Chr19:15468716 [GRCh38]
Chr19:15579527 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.877C>T (p.Arg293Trp) single nucleotide variant not specified [RCV004187876] Chr19:15475793 [GRCh38]
Chr19:15586604 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.1295T>G (p.Met432Arg) single nucleotide variant not specified [RCV004176537] Chr19:15471938 [GRCh38]
Chr19:15582749 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.595G>A (p.Val199Ile) single nucleotide variant not specified [RCV004201339] Chr19:15476075 [GRCh38]
Chr19:15586886 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.674G>A (p.Gly225Glu) single nucleotide variant not specified [RCV004085422] Chr19:15475996 [GRCh38]
Chr19:15586807 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.1400G>A (p.Gly467Asp) single nucleotide variant not specified [RCV004159815] Chr19:15469873 [GRCh38]
Chr19:15580684 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.1668T>G (p.Ser556Arg) single nucleotide variant not specified [RCV004091112] Chr19:15468726 [GRCh38]
Chr19:15579537 [GRCh37]
Chr19:19p13.12
likely benign
NM_052890.4(PGLYRP2):c.1199T>C (p.Leu400Pro) single nucleotide variant not specified [RCV004092249] Chr19:15472034 [GRCh38]
Chr19:15582845 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.304G>A (p.Val102Ile) single nucleotide variant not specified [RCV004077013] Chr19:15476366 [GRCh38]
Chr19:15587177 [GRCh37]
Chr19:19p13.12
uncertain significance
GRCh38/hg38 19p13.12-13.11(chr19:15014099-16261691) copy number loss Chromosome 19p13.13 deletion syndrome [RCV003223562] Chr19:15014099..16261691 [GRCh38]
Chr19:19p13.12-13.11
pathogenic|uncertain significance
NM_052890.4(PGLYRP2):c.404G>A (p.Arg135His) single nucleotide variant not specified [RCV004257583] Chr19:15476266 [GRCh38]
Chr19:15587077 [GRCh37]
Chr19:19p13.12
likely benign
NM_052890.4(PGLYRP2):c.325G>C (p.Gly109Arg) single nucleotide variant not specified [RCV004278778] Chr19:15476345 [GRCh38]
Chr19:15587156 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.1025T>G (p.Leu342Arg) single nucleotide variant not specified [RCV004354575] Chr19:15475645 [GRCh38]
Chr19:15586456 [GRCh37]
Chr19:19p13.12
uncertain significance
GRCh37/hg19 19p13.12-13.11(chr19:14888106-17360864)x3 copy number gain not provided [RCV003485195] Chr19:14888106..17360864 [GRCh37]
Chr19:19p13.12-13.11
uncertain significance
GRCh37/hg19 19p13.13-13.11(chr19:13970692-18139376)x3 copy number gain not specified [RCV003986122] Chr19:13970692..18139376 [GRCh37]
Chr19:19p13.13-13.11
uncertain significance
GRCh37/hg19 19p13.12(chr19:15263384-15683826)x3 copy number gain not specified [RCV003986112] Chr19:15263384..15683826 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.31G>A (p.Gly11Arg) single nucleotide variant not specified [RCV004498685] Chr19:15479341 [GRCh38]
Chr19:15590152 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.1573C>A (p.Leu525Met) single nucleotide variant not specified [RCV004498684] Chr19:15469700 [GRCh38]
Chr19:15580511 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.956G>A (p.Arg319Gln) single nucleotide variant not specified [RCV004498689] Chr19:15475714 [GRCh38]
Chr19:15586525 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.1055A>G (p.Gln352Arg) single nucleotide variant not specified [RCV004498683] Chr19:15475615 [GRCh38]
Chr19:15586426 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.430A>G (p.Ser144Gly) single nucleotide variant not specified [RCV004498686] Chr19:15476240 [GRCh38]
Chr19:15587051 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.439G>T (p.Ala147Ser) single nucleotide variant not specified [RCV004498687] Chr19:15476231 [GRCh38]
Chr19:15587042 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.767G>A (p.Arg256Gln) single nucleotide variant not specified [RCV004659927] Chr19:15475903 [GRCh38]
Chr19:15586714 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.1237T>C (p.Tyr413His) single nucleotide variant not specified [RCV004659928] Chr19:15471996 [GRCh38]
Chr19:15582807 [GRCh37]
Chr19:19p13.12
uncertain significance
NM_052890.4(PGLYRP2):c.403C>A (p.Arg135Ser) single nucleotide variant not specified [RCV004655823] Chr19:15476267 [GRCh38]
Chr19:15587078 [GRCh37]
Chr19:19p13.12
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1195
Count of miRNA genes:723
Interacting mature miRNAs:814
Transcripts:ENST00000292609, ENST00000340880, ENST00000594637, ENST00000601792
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407235204GWAS884180_Hblood protein measurement QTL GWAS884180 (human)1e-21blood protein measurementblood protein measurement (CMO:0000028)191546947915469480Human
407205700GWAS854676_Hblood protein measurement QTL GWAS854676 (human)1e-106blood protein measurementblood protein measurement (CMO:0000028)191546947915469480Human
406893186GWAS542162_Htransmembrane protein 2 measurement QTL GWAS542162 (human)1e-17transmembrane protein 2 measurement191547507815475079Human
1581534BP76_HBlood pressure QTL 76 (human)20.001Blood pressurepulse pressure19116075902Human
1581535BP65_HBlood pressure QTL 65 (human)3.10.001Blood pressurepulse pressure19116075902Human
406892490GWAS541466_Hglycoprotein hormone alpha-2 measurement QTL GWAS541466 (human)3e-82glycoprotein hormone alpha-2 measurement191547275115472752Human
1298499UAE1_HUrinary albumin excretion QTL 1 (human)2.730.0009Urinary albumin excretionurine albumin:creatinine ratio (ACR)19116075902Human
1300034BP50_HBlood pressure QTL 50 (human)2.10.00094Blood pressuresystolic191108946337089463Human
406968592GWAS617568_Hprotein measurement QTL GWAS617568 (human)6e-195protein measurement191547513415475135Human
407202131GWAS851107_Hblood protein measurement QTL GWAS851107 (human)4e-18blood protein measurementblood protein measurement (CMO:0000028)191546984715469848Human
406960603GWAS609579_Hprotein measurement QTL GWAS609579 (human)5e-461protein measurement191547205215472053Human
406891675GWAS540651_Harf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 measurement QTL GWAS540651 (human)3e-27arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 measurement191547156915471570Human
406894047GWAS543023_Hguanylyl cyclase-activating protein 1 measurement QTL GWAS543023 (human)2e-55guanylyl cyclase-activating protein 1 measurement191547586115475862Human
406961121GWAS610097_Hprotein measurement QTL GWAS610097 (human)2e-14protein measurement191547030815470309Human
1643451SLIPL6_HSerum lipid level QTL 6 (human)2.190.0008Lipid level19116075902Human
406951780GWAS600756_Hprotein LDOC1 measurement QTL GWAS600756 (human)3e-97protein LDOC1 measurement191547205215472053Human
406893800GWAS542776_Hsubmaxillary gland androgen-regulated protein 3A measurement QTL GWAS542776 (human)1e-84submaxillary gland androgen-regulated protein 3A measurement191546947915469480Human
406973801GWAS622777_Hmacrophage scavenger receptor types I and II measurement QTL GWAS622777 (human)2e-127macrophage scavenger receptor types I and II measurement191546984715469848Human
406892392GWAS541368_Hprotein LDOC1 measurement QTL GWAS541368 (human)6e-76protein LDOC1 measurement191547205215472053Human
406951853GWAS600829_Hprotein measurement QTL GWAS600829 (human)1e-27protein measurement191546984715469848Human
407214965GWAS863941_Hblood protein measurement QTL GWAS863941 (human)2e-173blood protein measurementblood protein measurement (CMO:0000028)191547167415471675Human
407203760GWAS852736_Hblood protein measurement QTL GWAS852736 (human)4e-14blood protein measurementblood protein measurement (CMO:0000028)191546984715469848Human
406891255GWAS540231_Hadrenomedullin measurement QTL GWAS540231 (human)2e-26kidney adrenomedullin amount (VT:0010754)kidney adrenomedullin level (CMO:0002916)191547653415476535Human
407242302GWAS891278_Hblood protein measurement QTL GWAS891278 (human)7e-106blood protein measurementblood protein measurement (CMO:0000028)191546947915469480Human
406995960GWAS644936_Hlevel of N-acetylmuramoyl-L-alanine amidase in blood serum QTL GWAS644936 (human)2e-25level of N-acetylmuramoyl-L-alanine amidase in blood serum191547590015475901Human
2314591INSUL4_HInsulin level QTL 4 (human)3.80.000038Insulin levelfasting19116075902Human
1298476BP3_HBlood pressure QTL 3 (human)2.4Blood pressuresystolic19116075902Human

Markers in Region
PGLYRP2_3637  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371915,579,384 - 15,580,182UniSTSGRCh37
Build 361915,440,384 - 15,441,182RGDNCBI36
Celera1915,476,196 - 15,476,994RGD
HuRef1915,147,135 - 15,147,933UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
847 1400 1609 1128 2602 1276 1827 583 1568 448 1712 4406 4139 27 1485 509 1241 1146 136

Sequence


Ensembl Acc Id: ENST00000292609   ⟹   ENSP00000292609
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1915,468,645 - 15,479,501 (-)Ensembl
Ensembl Acc Id: ENST00000340880   ⟹   ENSP00000345968
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1915,468,645 - 15,479,501 (-)Ensembl
Ensembl Acc Id: ENST00000594637   ⟹   ENSP00000470112
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1915,476,353 - 15,479,831 (-)Ensembl
Ensembl Acc Id: ENST00000601792   ⟹   ENSP00000472856
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1915,476,235 - 15,498,956 (-)Ensembl
RefSeq Acc Id: NM_001363546   ⟹   NP_001350475
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381915,468,645 - 15,479,501 (-)NCBI
T2T-CHM13v2.01915,593,641 - 15,604,523 (-)NCBI
Sequence:
RefSeq Acc Id: NM_052890   ⟹   NP_443122
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381915,468,645 - 15,479,501 (-)NCBI
GRCh371915,579,456 - 15,590,315 (-)ENTREZGENE
Build 361915,440,456 - 15,451,315 (-)NCBI Archive
HuRef1915,147,207 - 15,158,066 (-)ENTREZGENE
CHM1_11915,579,067 - 15,589,927 (-)NCBI
T2T-CHM13v2.01915,593,641 - 15,604,523 (-)NCBI
Sequence:
RefSeq Acc Id: NP_443122   ⟸   NM_052890
- Peptide Label: isoform 1 precursor
- UniProtKB: Q96N74 (UniProtKB/Swiss-Prot),   Q68CK1 (UniProtKB/Swiss-Prot),   B7ZM33 (UniProtKB/Swiss-Prot),   B2RMZ2 (UniProtKB/Swiss-Prot),   A8K8C7 (UniProtKB/Swiss-Prot),   A8K050 (UniProtKB/Swiss-Prot),   Q9UC60 (UniProtKB/Swiss-Prot),   Q96PD5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001350475   ⟸   NM_001363546
- Peptide Label: isoform 2 precursor
Ensembl Acc Id: ENSP00000470112   ⟸   ENST00000594637
Ensembl Acc Id: ENSP00000292609   ⟸   ENST00000292609
Ensembl Acc Id: ENSP00000472856   ⟸   ENST00000601792
Ensembl Acc Id: ENSP00000345968   ⟸   ENST00000340880
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q96PD5-F1-model_v2 AlphaFold Q96PD5 1-576 view protein structure

Promoters
RGD ID:7238905
Promoter ID:EPDNEW_H25198
Type:initiation region
Name:PGLYRP2_1
Description:peptidoglycan recognition protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381915,479,501 - 15,479,561EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:30013 AgrOrtholog
COSMIC PGLYRP2 COSMIC
Ensembl Genes ENSG00000161031 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000292609 ENTREZGENE
  ENST00000292609.8 UniProtKB/Swiss-Prot
  ENST00000340880 ENTREZGENE
  ENST00000340880.5 UniProtKB/Swiss-Prot
  ENST00000594637.1 UniProtKB/TrEMBL
  ENST00000601792.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.80.10 UniProtKB/Swiss-Prot
GTEx ENSG00000161031 GTEx
HGNC ID HGNC:30013 ENTREZGENE
Human Proteome Map PGLYRP2 Human Proteome Map
InterPro Amidase/PGRP_sf UniProtKB/Swiss-Prot
  Amidase_domain UniProtKB/Swiss-Prot
  PGRP UniProtKB/Swiss-Prot
  PGRP_domain_met/bac UniProtKB/Swiss-Prot
KEGG Report hsa:114770 UniProtKB/Swiss-Prot
NCBI Gene 114770 ENTREZGENE
OMIM 608199 OMIM
PANTHER N-ACETYLMURAMOYL-L-ALANINE AMIDASE UniProtKB/Swiss-Prot
  PTHR11022 UniProtKB/Swiss-Prot
Pfam Amidase_2 UniProtKB/Swiss-Prot
PharmGKB PA134929965 PharmGKB
SMART Ami_2 UniProtKB/Swiss-Prot
  PGRP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF55846 UniProtKB/Swiss-Prot
UniProt A8K050 ENTREZGENE
  A8K8C7 ENTREZGENE
  B2RMZ2 ENTREZGENE
  B7ZM33 ENTREZGENE
  M0QYW3_HUMAN UniProtKB/TrEMBL
  M0R2W8_HUMAN UniProtKB/TrEMBL
  PGRP2_HUMAN UniProtKB/Swiss-Prot
  Q68CK1 ENTREZGENE
  Q96N74 ENTREZGENE
  Q96PD5 ENTREZGENE
  Q9UC60 ENTREZGENE
UniProt Secondary A8K050 UniProtKB/Swiss-Prot
  A8K8C7 UniProtKB/Swiss-Prot
  B2RMZ2 UniProtKB/Swiss-Prot
  B7ZM33 UniProtKB/Swiss-Prot
  Q68CK1 UniProtKB/Swiss-Prot
  Q96N74 UniProtKB/Swiss-Prot
  Q9UC60 UniProtKB/Swiss-Prot