MRGPRE (MAS related GPR family member E) - Rat Genome Database

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Gene: MRGPRE (MAS related GPR family member E) Homo sapiens
Analyze
Symbol: MRGPRE
Name: MAS related GPR family member E
RGD ID: 1344531
HGNC Page HGNC:30694
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: G protein-coupled receptor 167; G-protein coupled receptor 167; GPR167; mas-related G protein-coupled MRGE; Mas-related G protein-coupled receptor F; mas-related G-protein coupled receptor member E; MAS-related GPR, member E; MGC138408; MGRF; MRGE
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38113,225,030 - 3,232,417 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl113,225,030 - 3,232,417 (-)EnsemblGRCh38hg38GRCh38
GRCh37113,246,260 - 3,253,647 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36113,205,617 - 3,210,192 (-)NCBINCBI36Build 36hg18NCBI36
Celera113,284,634 - 3,289,260 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
CHM1_1113,248,699 - 3,253,274 (-)NCBICHM1_1
T2T-CHM13v2.0113,316,000 - 3,323,368 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11551509   PMID:12477932   PMID:12679517   PMID:15489334   PMID:21873635   PMID:23412934   PMID:24270810   PMID:24583173  


Genomics

Comparative Map Data
MRGPRE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38113,225,030 - 3,232,417 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl113,225,030 - 3,232,417 (-)EnsemblGRCh38hg38GRCh38
GRCh37113,246,260 - 3,253,647 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36113,205,617 - 3,210,192 (-)NCBINCBI36Build 36hg18NCBI36
Celera113,284,634 - 3,289,260 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
CHM1_1113,248,699 - 3,253,274 (-)NCBICHM1_1
T2T-CHM13v2.0113,316,000 - 3,323,368 (-)NCBIT2T-CHM13v2.0
Mrgpre
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397143,332,100 - 143,338,237 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7143,332,100 - 143,338,237 (-)EnsemblGRCm39 Ensembl
GRCm387143,778,363 - 143,784,500 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7143,778,363 - 143,784,500 (-)EnsemblGRCm38mm10GRCm38
MGSCv377150,964,268 - 150,970,405 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367143,587,755 - 143,593,708 (-)NCBIMGSCv36mm8
Celera7143,534,742 - 143,540,879 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.31NCBI
Mrgpre
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81208,393,141 - 208,401,252 (-)NCBIGRCr8
mRatBN7.21198,963,786 - 198,969,862 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1198,963,787 - 198,969,521 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1207,345,752 - 207,346,681 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01214,427,692 - 214,428,621 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01207,101,860 - 207,102,789 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01216,969,464 - 216,973,936 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,970,254 - 216,971,183 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01223,825,104 - 223,830,426 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41204,171,075 - 204,172,004 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11204,324,527 - 204,325,457 (-)NCBI
Celera1196,529,375 - 196,530,304 (-)NCBICelera
Cytogenetic Map1q42NCBI
Mrgpre
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542214,976,730 - 14,982,295 (-)NCBIChiLan1.0ChiLan1.0
MRGPRE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v295,626,066 - 5,634,066 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1114,837,374 - 4,845,365 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0113,239,980 - 3,247,880 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1113,262,444 - 3,267,440 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl113,263,249 - 3,264,187 (-)Ensemblpanpan1.1panPan2
Mrgpre
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049473,401,521 - 3,406,868 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367941,346,350 - 1,347,939 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367941,346,350 - 1,347,291 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC102159152
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.122,329,261 - 2,330,710 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22776,673 - 777,698 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MRGPRE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.113,041,908 - 3,049,499 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl13,045,744 - 3,046,673 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038100,238,653 - 100,243,615 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrgpre
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476715,979,561 - 15,988,846 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476715,976,090 - 15,988,969 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MRGPRE
16 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11p15.5-15.4(chr11:196966-3377077)x3 copy number gain See cases [RCV000050947] Chr11:196966..3377077 [GRCh38]
Chr11:196966..3398307 [GRCh37]
Chr11:186966..3354883 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196966-4435344)x3 copy number gain See cases [RCV000050927] Chr11:196966..4435344 [GRCh38]
Chr11:196966..4456574 [GRCh37]
Chr11:186966..4413150 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:218365-3377077)x3 copy number gain See cases [RCV000053614] Chr11:218365..3377077 [GRCh38]
Chr11:218365..3398307 [GRCh37]
Chr11:208365..3354883 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196966-3624139)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053592]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053592]|See cases [RCV000053592] Chr11:196966..3624139 [GRCh38]
Chr11:196966..3645369 [GRCh37]
Chr11:186966..3601945 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-13(chr11:202758-31726224)x3 copy number gain See cases [RCV000053613] Chr11:202758..31726224 [GRCh38]
Chr11:202758..31747772 [GRCh37]
Chr11:192758..31704348 [NCBI36]
Chr11:11p15.5-13
pathogenic
NM_001039165.2(MRGPRE):c.750C>A (p.Phe250Leu) single nucleotide variant Malignant melanoma [RCV000069321] Chr11:3228050 [GRCh38]
Chr11:3249280 [GRCh37]
Chr11:3205856 [NCBI36]
Chr11:11p15.4
not provided
GRCh38/hg38 11p15.5-15.1(chr11:446754-18904742)x3 copy number gain See cases [RCV000133997] Chr11:446754..18904742 [GRCh38]
Chr11:446754..18926289 [GRCh37]
Chr11:436754..18882865 [NCBI36]
Chr11:11p15.5-15.1
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:1537379-3360769)x3 copy number gain See cases [RCV000136847] Chr11:1537379..3360769 [GRCh38]
Chr11:1558609..3381999 [GRCh37]
Chr11:1515185..3338575 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:1975511-3624139)x1 copy number loss See cases [RCV000137066] Chr11:1975511..3624139 [GRCh38]
Chr11:1996741..3645369 [GRCh37]
Chr11:1953317..3601945 [NCBI36]
Chr11:11p15.5-15.4
uncertain significance
GRCh38/hg38 11p15.5-15.4(chr11:61793-10727969)x3 copy number gain See cases [RCV000139987] Chr11:61793..10727969 [GRCh38]
Chr11:61793..10749516 [GRCh37]
Chr11:51793..10706092 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196855-5321874)x3 copy number gain See cases [RCV000142890] Chr11:196855..5321874 [GRCh38]
Chr11:196855..5343104 [GRCh37]
Chr11:186855..5299680 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:193187-5291338)x3 copy number gain See cases [RCV000446036] Chr11:193187..5291338 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230615-6644927)x3 copy number gain See cases [RCV000449417] Chr11:230615..6644927 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
GRCh37/hg19 11p15.5-12(chr11:230615-37698540)x3 copy number gain See cases [RCV000511561] Chr11:230615..37698540 [GRCh37]
Chr11:11p15.5-12
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-14.3(chr11:230615-25584362)x3 copy number gain See cases [RCV000512225] Chr11:230615..25584362 [GRCh37]
Chr11:11p15.5-14.3
pathogenic
GRCh37/hg19 11p15.5-13(chr11:230615-31995219)x3 copy number gain See cases [RCV000512477] Chr11:230615..31995219 [GRCh37]
Chr11:11p15.5-13
pathogenic
GRCh37/hg19 11p15.5-15.1(chr11:230615-17099213)x3 copy number gain not provided [RCV000683372] Chr11:230615..17099213 [GRCh37]
Chr11:11p15.5-15.1
pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230615-9704511)x3 copy number gain not provided [RCV000683369] Chr11:230615..9704511 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-15.3(chr11:193146-12643136) copy number gain Silver-Russell syndrome 1 [RCV000767567] Chr11:193146..12643136 [GRCh37]
Chr11:11p15.5-15.3
pathogenic
NM_001039165.4(MRGPRE):c.628C>T (p.Pro210Ser) single nucleotide variant not specified [RCV004301593] Chr11:3228172 [GRCh38]
Chr11:3249402 [GRCh37]
Chr11:11p15.4
uncertain significance
GRCh37/hg19 11p15.5-13(chr11:235934-33826995)x3 copy number gain not provided [RCV001006372] Chr11:235934..33826995 [GRCh37]
Chr11:11p15.5-13
pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230615-4851537)x3 copy number gain See cases [RCV001263059] Chr11:230615..4851537 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:210300-8664358)x3 copy number gain Silver-Russell syndrome 1 [RCV001263222] Chr11:210300..8664358 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
NC_000011.9:g.(?_298501)_(4113028_?)dup duplication Early infantile epileptic encephalopathy with suppression bursts [RCV001316682] Chr11:298501..4113028 [GRCh37]
Chr11:11p15.5-15.4
uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:10701-5080415)x2 copy number gain See cases [RCV001310286] Chr11:10701..5080415 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230615-5525355)x3 copy number gain not provided [RCV001825269] Chr11:230615..5525355 [GRCh37]
Chr11:11p15.5-15.4
not provided
NC_000011.9:g.(?_721044)_(3988932_?)dup duplication not provided [RCV003113442] Chr11:721044..3988932 [GRCh37]
Chr11:11p15.5-15.4
uncertain significance
GRCh37/hg19 11p15.5-14.2(chr11:230615-26881146)x3 copy number gain See cases [RCV002286351] Chr11:230615..26881146 [GRCh37]
Chr11:11p15.5-14.2
pathogenic
NC_000011.10:g.(499700_4999400)_(5279346_5279697)del deletion Thalassemia, gamma-delta-beta [RCV000015529] Chr11:4999400..5279346 [GRCh38]
Chr11:11p15.5-15.4
pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230616-8250724)x3 copy number gain not provided [RCV002472435] Chr11:230616..8250724 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
NM_001039165.4(MRGPRE):c.578G>A (p.Cys193Tyr) single nucleotide variant not specified [RCV004238832] Chr11:3228222 [GRCh38]
Chr11:3249452 [GRCh37]
Chr11:11p15.4
uncertain significance
NM_001039165.4(MRGPRE):c.772G>A (p.Ala258Thr) single nucleotide variant not specified [RCV004218550] Chr11:3228028 [GRCh38]
Chr11:3249258 [GRCh37]
Chr11:11p15.4
uncertain significance
NM_001039165.4(MRGPRE):c.190G>A (p.Asp64Asn) single nucleotide variant not specified [RCV004140789] Chr11:3228610 [GRCh38]
Chr11:3249840 [GRCh37]
Chr11:11p15.4
uncertain significance
NM_001039165.4(MRGPRE):c.830G>A (p.Gly277Asp) single nucleotide variant not specified [RCV004227008] Chr11:3227970 [GRCh38]
Chr11:3249200 [GRCh37]
Chr11:11p15.4
uncertain significance
NM_001039165.4(MRGPRE):c.304C>T (p.Leu102=) single nucleotide variant not specified [RCV004227567] Chr11:3228496 [GRCh38]
Chr11:3249726 [GRCh37]
Chr11:11p15.4
uncertain significance
NM_001039165.4(MRGPRE):c.55G>T (p.Glu19Ter) single nucleotide variant not specified [RCV004183046] Chr11:3228745 [GRCh38]
Chr11:3249975 [GRCh37]
Chr11:11p15.4
uncertain significance
NM_001039165.4(MRGPRE):c.521G>A (p.Cys174Tyr) single nucleotide variant not specified [RCV004175576] Chr11:3228279 [GRCh38]
Chr11:3249509 [GRCh37]
Chr11:11p15.4
likely benign
NM_001039165.4(MRGPRE):c.601C>T (p.Leu201=) single nucleotide variant not specified [RCV004209656] Chr11:3228199 [GRCh38]
Chr11:3249429 [GRCh37]
Chr11:11p15.4
uncertain significance
NM_001039165.4(MRGPRE):c.521G>T (p.Cys174Phe) single nucleotide variant not specified [RCV004175516] Chr11:3228279 [GRCh38]
Chr11:3249509 [GRCh37]
Chr11:11p15.4
uncertain significance
NM_001039165.4(MRGPRE):c.892G>A (p.Ala298Thr) single nucleotide variant not specified [RCV004150024] Chr11:3227908 [GRCh38]
Chr11:3249138 [GRCh37]
Chr11:11p15.4
uncertain significance
NM_001039165.4(MRGPRE):c.911G>A (p.Arg304His) single nucleotide variant not specified [RCV004256118] Chr11:3227889 [GRCh38]
Chr11:3249119 [GRCh37]
Chr11:11p15.4
uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:192764-3362853)x3 copy number gain not provided [RCV003484828] Chr11:192764..3362853 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230615-8821443)x3 copy number gain Russell-Silver syndrome [RCV003444025] Chr11:230615..8821443 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
NM_001039165.4(MRGPRE):c.775G>A (p.Ala259Thr) single nucleotide variant not specified [RCV004499242] Chr11:3228025 [GRCh38]
Chr11:3249255 [GRCh37]
Chr11:11p15.4
uncertain significance
NM_001039165.4(MRGPRE):c.671T>C (p.Leu224Pro) single nucleotide variant not specified [RCV004499239] Chr11:3228129 [GRCh38]
Chr11:3249359 [GRCh37]
Chr11:11p15.4
uncertain significance
NM_001039165.4(MRGPRE):c.398G>A (p.Cys133Tyr) single nucleotide variant not specified [RCV004643555] Chr11:3228402 [GRCh38]
Chr11:3249632 [GRCh37]
Chr11:11p15.4
uncertain significance
NM_001039165.4(MRGPRE):c.401G>A (p.Arg134His) single nucleotide variant not specified [RCV004629121] Chr11:3228399 [GRCh38]
Chr11:3249629 [GRCh37]
Chr11:11p15.4
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:763
Count of miRNA genes:474
Interacting mature miRNAs:527
Transcripts:ENST00000389832, ENST00000436689
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407160421GWAS809397_Hgut microbiome measurement QTL GWAS809397 (human)0.000006gut microbiome measurement1132277123227713Human
1558691SCL8_HSerum cholesterol level QTL 8 (human)1.2Lipid levelHDL cholesterol1115227071Human
1559107SCL32_HSerum cholesterol level QTL 32 (human)3.27Lipid levelLDL cholesterol11289243028892430Human
406983910GWAS632886_HAbnormality of chromosome segregation QTL GWAS632886 (human)0.000008Abnormality of chromosome segregation1132285993228600Human
1559113SCL31_HSerum cholesterol level QTL 31 (human)3.72Lipid levelLDL cholesterol11289243028892430Human
407187434GWAS836410_Hmigraine disorder QTL GWAS836410 (human)3e-16migraine disorder1132287543228755Human

Markers in Region
UniSTS:485316  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37113,249,041 - 3,250,060UniSTSGRCh37
Celera113,284,634 - 3,285,653UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
696 1809 1615 1609 3737 1115 1386 3 197 909 49 1486 4058 4033 11 2930 538 1403 1091 152

Sequence


Ensembl Acc Id: ENST00000389832   ⟹   ENSP00000374482
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl113,225,030 - 3,232,417 (-)Ensembl
RefSeq Acc Id: NM_001039165   ⟹   NP_001034254
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38113,225,030 - 3,232,417 (-)NCBI
GRCh37113,249,041 - 3,253,616 (-)RGD
Build 36113,205,617 - 3,210,192 (-)NCBI Archive
Celera113,284,634 - 3,289,260 (-)RGD
CHM1_1113,248,699 - 3,253,274 (-)NCBI
T2T-CHM13v2.0113,316,000 - 3,323,368 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001034254   ⟸   NM_001039165
- UniProtKB: Q2M1V7 (UniProtKB/Swiss-Prot),   Q86SM8 (UniProtKB/Swiss-Prot),   W4VSQ4 (UniProtKB/TrEMBL),   B4DF56 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000374482   ⟸   ENST00000389832
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q86SM8-F1-model_v2 AlphaFold Q86SM8 1-312 view protein structure

Promoters
RGD ID:6789115
Promoter ID:HG_KWN:12039
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:NM_001039165
Position:
Human AssemblyChrPosition (strand)Source
Build 36113,209,576 - 3,210,076 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:30694 AgrOrtholog
COSMIC MRGPRE COSMIC
Ensembl Genes ENSG00000184350 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000389832 ENTREZGENE
  ENST00000389832.7 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000184350 GTEx
HGNC ID HGNC:30694 ENTREZGENE
Human Proteome Map MRGPRE Human Proteome Map
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRGPCRE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRGPCRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:116534 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 116534 ENTREZGENE
OMIM 607232 OMIM
PANTHER PTHR11334 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11334:SF26 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134939296 PharmGKB
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRGPCRE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRGPCRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B4DF56 ENTREZGENE, UniProtKB/TrEMBL
  L8E724_HUMAN UniProtKB/TrEMBL
  MRGRE_HUMAN UniProtKB/Swiss-Prot
  Q2M1V7 ENTREZGENE
  Q86SM8 ENTREZGENE
  W4VSQ4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q2M1V7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-01 MRGPRE  MAS related GPR family member E    MAS-related GPR, member E  Symbol and/or name change 5135510 APPROVED