MBL1P (mannose binding lectin 1, pseudogene)

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Gene: MBL1P (mannose binding lectin 1, pseudogene) Homo sapiens

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Symbol:

MBL1P

Name:

mannose binding lectin 1, pseudogene

RGD ID:

1343390

HGNC Page

HGNC:6921

Description:

Predicted to enable several functions, including D-mannose binding activity; calcium-dependent carbohydrate binding activity; and protein homodimerization activity. Predicted to be involved in protein homotrimerization. Predicted to act upstream of or within defense response to other organism and positive regulation of phagocytosis. Predicted to be located in extracellular space.

Type:

pseudo (Ensembl: lncRNA)

RefSeq Status:

VALIDATED

Previously known as:

COLEC3P; mannose-binding lectin (protein A) 1, pseudogene; MBL1P1

RGD Orthologs

Mouse

Rat

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	79,920,178 - 79,923,119 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	79,920,327 - 79,923,032 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p14 Ensembl	10	79,920,178 - 79,923,119 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	81,679,934 - 81,682,875 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	81,669,914 - 81,672,855 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	81,669,913 - 81,672,855	NCBI
Celera	10	75,670,857 - 75,673,805 (+)	NCBI		Celera
Cytogenetic Map	10	q22.3	NCBI
HuRef	10	75,522,689 - 75,525,630 (+)	NCBI		HuRef
CHM1_1	10	81,962,581 - 81,965,522 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	80,789,562 - 80,792,503 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

aspergillosis (ISO)

herpes simplex (ISO)

Kawasaki disease (ISO)

Myocardial Reperfusion Injury (ISO)

obesity (ISO)

Reperfusion Injury (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (ISO)

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2,4-dinitrotoluene (ISO)

2,6-dinitrotoluene (ISO)

3H-1,2-dithiole-3-thione (ISO)

aflatoxin B1 (ISO)

ammonium chloride (ISO)

benzo[a]pyrene (EXP)

bisphenol A (ISO)

butanal (EXP)

clofibric acid (ISO)

copper atom (ISO)

copper(0) (ISO)

cyclosporin A (ISO)

diclofenac (ISO)

endosulfan (ISO)

epoxiconazole (ISO)

felbamate (ISO)

fipronil (EXP)

fumonisin B1 (ISO)

genistein (ISO)

gentamycin (ISO)

gliotoxin (ISO)

glyphosate (ISO)

indometacin (ISO)

lead(0) (EXP)

lipopolysaccharide (EXP)

mercury dichloride (ISO)

N,N-diethyl-m-toluamide (EXP)

N-nitrosodiethylamine (ISO)

nefazodone (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

phenytoin (ISO)

pirinixic acid (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (EXP)

silicon dioxide (EXP)

silver atom (ISO)

silver(0) (ISO)

tetrachloromethane (ISO)

thioacetamide (ISO)

titanium dioxide (ISO)

trichloroethene (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

complement activation, lectin pathway (ISO)

defense response to Gram-positive bacterium (ISO)

killing by host of symbiont cells (ISO)

positive regulation of phagocytosis (ISO)

protein homotrimerization (ISO)

Cellular Component

extracellular space (ISO)

Molecular Function

calcium ion binding (ISO)

calcium-dependent carbohydrate binding (ISO)

calcium-dependent protein binding (ISO)

D-mannose binding (ISO)

identical protein binding (ISO)

oligosaccharide binding (ISO)

phosphatidylinositol-4-phosphate binding (ISO)

polysaccharide binding (ISO)

protease binding (ISO)

protein binding (ISO)

protein homodimerization activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9501312	PMID:15458704	PMID:15716605	PMID:16115813	PMID:20210993	PMID:21889966	PMID:24008740	PMID:24576294

Genomics

Comparative Map Data

MBL1P
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	79,920,178 - 79,923,119 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	79,920,327 - 79,923,032 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p14 Ensembl	10	79,920,178 - 79,923,119 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	81,679,934 - 81,682,875 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	81,669,914 - 81,672,855 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	81,669,913 - 81,672,855	NCBI
Celera	10	75,670,857 - 75,673,805 (+)	NCBI		Celera
Cytogenetic Map	10	q22.3	NCBI
HuRef	10	75,522,689 - 75,525,630 (+)	NCBI		HuRef
CHM1_1	10	81,962,581 - 81,965,522 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	80,789,562 - 80,792,503 (+)	NCBI		T2T-CHM13v2.0

Mbl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	40,873,413 - 40,885,861 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	40,873,415 - 40,881,558 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	41,151,456 - 41,163,904 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	41,151,458 - 41,159,601 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	41,964,745 - 41,972,248 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	40,060,169 - 40,067,672 (+)	NCBI		MGSCv36	mm8
Celera	14	37,311,454 - 37,318,966 (+)	NCBI		Celera
Cytogenetic Map	14	B	NCBI
cM Map	14	22.36	NCBI

Mbl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	17,063,232 - 17,069,271 (+)	NCBI		GRCr8
mRatBN7.2	16	17,029,146 - 17,035,187 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	17,029,118 - 17,035,174 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	17,093,376 - 17,099,473 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	18,221,699 - 18,227,754 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	17,146,274 - 17,152,371 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	18,736,154 - 18,742,193 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	18,736,154 - 18,742,193 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	18,604,750 - 18,610,789 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	17,591,820 - 17,597,859 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	17,591,817 - 17,597,857 (+)	NCBI
Celera	16	17,254,917 - 17,260,956 (+)	NCBI		Celera
RH 3.4 Map	16	167.5	RGD
Cytogenetic Map	16	p14	NCBI

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	637
Count of miRNA genes:	480
Interacting mature miRNAs:	512
Transcripts:	ENST00000421889, ENST00000453174, ENST00000480805, ENST00000497731
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCh38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2314551	GLUCO52_H	Glucose level QTL 52 (human)	1.4		Glucose level		10	77605006	103605006	Human

Markers in Region

STS-H92757

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	10	81,681,179 - 81,681,335	UniSTS	GRCh37
Build 36	10	81,671,159 - 81,671,315	RGD	NCBI36
Celera	10	75,672,102 - 75,672,258	RGD
Cytogenetic Map	10	q22.3	UniSTS
HuRef	10	75,523,934 - 75,524,090	UniSTS
GeneMap99-GB4 RH Map	10	400.25	UniSTS
NCBI RH Map	10	985.0	UniSTS

Sequence

Nucleotide Sequences


RefSeq Transcripts	NR_002724	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF019382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL512662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY970670	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY970671	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY970672	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000480805

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	10	79,920,178 - 79,923,119 (+)	Ensembl

Ensembl Acc Id:

ENST00000497731

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	10	79,920,327 - 79,923,032 (+)	Ensembl

RefSeq Acc Id:

NR_002724

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	10	79,920,178 - 79,923,119 (+)	NCBI
GRCh37	10	81,679,934 - 81,682,875 (+)	RGD
Build 36	10	81,669,914 - 81,672,855 (+)	NCBI Archive
Celera	10	75,670,857 - 75,673,805 (+)	RGD
HuRef	10	75,522,689 - 75,525,630 (+)	ENTREZGENE
CHM1_1	10	81,962,581 - 81,965,522 (+)	NCBI
T2T-CHM13v2.0	10	80,789,562 - 80,792,503 (+)	NCBI

Sequence:

show sequence

GTCATTCAGAGCCAGGGGTTGTGATGGTCCCCTCTGTGTCCACTGTCCCCAGCACAGGGTCCAG
CACACCACAGTGGGTAGCAAATGCTATTTAAATGAGATGGGATGAAATTCCCTTCCTTCACTTT
CTTCACCTCAAGGTAAGGACCATGTTCCTGTTTCCATCATTCCCTGTCCTTCTCCTGTCTGTGG
TGACAGCTTCCTGCTCCAAAACAAAAGCCTGTGCAGATACCCAGAAGACCTGCTCCATGATTAC
CTGTGGCATCCCCGTCACCAATGGCACCCCAGGCAGAGATGGGCGAGATAGACCCAAGGGGGAA
AAGGGAGAGCCAGGTCTGGGACAGGTTTCTGTGGCTTCCTAAATCTCCACCTCCGGCAGGTGTT
CAAGCAAATCTGTGCTTGAGCCTGCCACACGAGGGTTAAAGCACAGACTTGGGGAGGCTCCCCT
TTCATCAGGACCCATGCTACACTCAGAACAACCCCTGTAAAATGCCATTGCCTCCAAAACAAAG
CTGTTCGTGGACTCTCTGGGATCCCATATTTCCACACAGGAACTGGGGGTGTGTGGTTGTCCCT
TCAGAGGGGTGTCCTGCCTGGTTGGGGAGCTGGCCTTGGTGCAGGCCCTCCACTAGGTTGCAGG
AGAGTCTTTCTTCTTTGGGTCAGATCACTGGCTCATTGGCTGTGCCGGGGGTGAACAGGAATGG
AGCATTGAGCTTTTGGGGAAAAAAAAAAGAGTGACAGCCACTGGGTCATCTTCCCTTTGTCTTG
CAACAGGTCAAGGGCTCAGAGGTTTGCAGGGCCCTCCTGGGAAGATGGGGCCCCCAGGAAACAC
AGGGACTTCTGGAATTCCAGGACCTAGGGGCCAAAAAGGAGATCGTGGGGACAATTCAGTTGCT
GAGGCTAAGCTGGCCAACTTAGAGAGAAAGCTATAGAGCCTGAGATCAGAACTGGACCACACGA
AGAAGCTGTAAGCCTTCTCCTTGGGGAAAATGTCTGGGAAGAAGCTTTTCGTGACCAATGGTGA
GCGGATGCCTTTCTCCAAAGTGAAGGCTCTGTGTGCTGGGCTCCAGGCCACAGTGGCTGCCCCC
AAGAATGCCGAGGAGAATAAGGCCATCCAGGATGTGGCCAAAGACACTGCCTTCCTGGGCATCA
CAGATGAGGCAACTGAAGGCCAGTTCATGTACTTGACGGGCAGGAGGCTGACCTACAGCAACTG
GAAGAAGGATGAGCCAAATGACCACGGCTCAGGGGAGGACTGCGTTATTCTCCTGAACAACGGG
CTCTGGAATGGCATCTCCTGCACCTCCTCCTTCATTGCCATCTGTGAGTTTCCTGCCTGAAGAG
GCACGTTCCTCAGCCCCCTCCTTGCCTCCCTGCTGAACTCTCTGCTGCTTTGGAAGAGAATTCA
ATGTTGGTTTTCTTCT

hide sequence

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:6921	AgrOrtholog
COSMIC	MBL1P	COSMIC
Ensembl Genes	ENSG00000242600	Ensembl
	ENSG00000293431	Ensembl, ENTREZGENE
Ensembl Transcript	ENST00000480805	ENTREZGENE
GTEx	ENSG00000242600	GTEx
	ENSG00000293431	GTEx
HGNC ID	HGNC:6921	ENTREZGENE
Human Proteome Map	MBL1P	Human Proteome Map
NCBI Gene	8512	ENTREZGENE
PharmGKB	PA30664	PharmGKB

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-06-30	MBL1P	mannose binding lectin 1, pseudogene		mannose-binding lectin (protein A) 1, pseudogene	Symbol and/or name change	5135510	APPROVED
2011-07-27	MBL1P	mannose-binding lectin (protein A) 1, pseudogene	MBL1P1	mannose-binding lectin (protein A) 1, pseudogene 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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