Lepr<sup>fa</sup> (leptin receptor; fa mutant) - Rat Genome Database

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Gene: Leprfa (leptin receptor; fa mutant) Rattus norvegicus
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Symbol: Leprfa
Name: leptin receptor; fa mutant
RGD ID: 13432153
Description: A missense mutation (an A to C conversion at nucleotide position 806) was found in the extracellular domain of all the isoforms in Zucker fatty (fa/fa) rats, which resulted in an amino acid change from Gln to Pro at + 269 (the Gln269Pro mutation).
ASSOCIATED WITH albuminuria; decreased survivor rate; hepatic steatosis; ASSOCIATED WITH Hyperphagia; Insulin Resistance; obesity
Type: allele  of Lepr  
Also known as: Leprfa
Is Marker For: Strains:   ZUC-LeprfaSte-/-   ZUC-Leprfa   Crl:ZUC-Leprfa   F344.ZUC-Leprfa/Tj   Crlj:ZUC-Leprfa   Crl:ZUC(Orl)-Leprfa   Slc:ZUC-Leprfa   Ho:ZFDM-Leprfa   SS.ZUC-Leprfa-/-/Slc   SS.ZUC-Leprfa-/+/Slc   BN.ZUC-Leprfa  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References


Genomics




Expression


Sequence

Nucleotide Sequences

Rat Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type
Leprfa-var1 chr5 120597857 120597857 A C point_mutation

Additional Information