Or11h4d (olfactory receptor family 11 subfamily H member 4D) - Rat Genome Database

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Gene: Or11h4d (olfactory receptor family 11 subfamily H member 4D) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or11h4d
Name: olfactory receptor family 11 subfamily H member 4D
RGD ID: 1334182
Description: Predicted to enable G protein-coupled receptor activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR11H4 (olfactory receptor family 11 subfamily H member 4).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: LOC103693822; olfactory receptor 11H4-like; olfactory receptor 1632; olfactory receptor gene Olr1632; olfactory receptor Olr1632; Olr1632
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,337,777 - 26,341,904 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.21523,864,250 - 23,865,224 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1523,864,191 - 23,868,317 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1526,635,478 - 26,636,452 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01527,596,866 - 27,597,840 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01525,844,036 - 25,845,010 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01527,499,024 - 27,499,998 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1527,499,024 - 27,499,998 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl1527,589,957 - 27,590,931 (-)Ensemblrn6Rnor6.0
Rnor_5.01531,434,278 - 31,437,533 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41526,609,177 - 26,610,151 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1524,192,981 - 24,193,955 (-)NCBICelera
RGSC_v3.11526,624,876 - 26,625,851 (-)NCBI
Cytogenetic Map15p14NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or11h4d
11 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:181
Count of miRNA genes:145
Interacting mature miRNAs:160
Transcripts:ENSRNOT00000050189
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151448116528469888Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)151985656634924750Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat


Expression

RNA-SEQ Expression

ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
reproductive system
2 2 2 2 10 2 12 10 2 9

Sequence


Ensembl Acc Id: ENSRNOT00000050189   ⟹   ENSRNOP00000048633
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1527,499,024 - 27,499,998 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080898   ⟹   ENSRNOP00000072069
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1527,589,957 - 27,590,931 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111286   ⟹   ENSRNOP00000094556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1523,864,191 - 23,868,317 (-)Ensembl
RefSeq Acc Id: NM_001000836   ⟹   NP_001000836
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,337,822 - 26,338,796 (-)NCBI
mRatBN7.21523,864,250 - 23,865,224 (-)NCBI
Rnor_6.01527,499,024 - 27,499,998 (-)NCBI
Rnor_5.01531,434,278 - 31,437,533 (-)NCBI
RGSC_v3.41526,609,177 - 26,610,151 (-)RGD
Celera1524,192,981 - 24,193,955 (-)RGD
Sequence:
RefSeq Acc Id: XM_063274510   ⟹   XP_063130580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,337,777 - 26,341,904 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001000836 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130580 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000072911.2
  ENSRNOP00000094556.1
  ENSRNOP00000112276
RefSeq Acc Id: NP_001000836   ⟸   NM_001000836
- UniProtKB: A0A0G2K453 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000048633   ⟸   ENSRNOT00000050189
Ensembl Acc Id: ENSRNOP00000072069   ⟸   ENSRNOT00000080898
Ensembl Acc Id: ENSRNOP00000094556   ⟸   ENSRNOT00000111286
RefSeq Acc Id: XP_063130580   ⟸   XM_063274510
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AMG7 (UniProtKB/TrEMBL),   A0A0G2K453 (UniProtKB/TrEMBL)
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZFZ6-F1-model_v2 AlphaFold D3ZFZ6 1-324 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1334182 AgrOrtholog
BioCyc Gene G2FUF-14069 BioCyc
Ensembl Genes ENSRNOG00000046582 Ensembl
  ENSRNOG00000059282 Ensembl
  ENSRNOG00000064971 UniProtKB/TrEMBL
  ENSRNOG00000067582 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000074338 ENTREZGENE
Ensembl Transcript ENSRNOT00000082085.2 UniProtKB/TrEMBL
  ENSRNOT00000111286.1 UniProtKB/TrEMBL
  ENSRNOT00000125126 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_GPCR1 UniProtKB/TrEMBL
NCBI Gene 405125 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 11H4 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or11h4d PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046582 RatGTEx
  ENSRNOG00000059282 RatGTEx
  ENSRNOG00000064971 RatGTEx
  ENSRNOG00000067582 RatGTEx
  ENSRNOG00000074338 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0G2K453 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMG7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or11h4d  olfactory receptor family 11 subfamily H member 4D  Olr1632  olfactory receptor 1632  Symbol and Name Changed 1299863 APPROVED
2021-03-09 Olr1632  olfactory receptor 1632  LOC103693822  olfactory receptor 11H4-like  Data merged from RGD:9330207 737654 PROVISIONAL
2014-08-25 LOC103693822  olfactory receptor 11H4-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Olr1632  olfactory receptor 1632   Olr1632_predicted  olfactory receptor 1632 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1632_predicted  olfactory receptor 1632 (predicted)      Symbol and Name status set to approved 70820 APPROVED