Or11g1 (olfactory receptor family 11 subfamily G member 1) - Rat Genome Database

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Gene: Or11g1 (olfactory receptor family 11 subfamily G member 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or11g1
Name: olfactory receptor family 11 subfamily G member 1
RGD ID: 1333946
Description: Predicted to enable G protein-coupled receptor activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR11G2 (olfactory receptor family 11 subfamily G member 2); INTERACTS WITH bisphenol A.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1615; olfactory receptor gene Olr1615; olfactory receptor Olr1615; Olr1615
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,067,065 - 26,085,314 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.21523,600,747 - 23,615,598 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1523,605,389 - 23,613,804 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1526,381,997 - 26,382,932 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01527,343,345 - 27,344,280 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01525,590,558 - 25,591,493 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01527,233,271 - 27,244,592 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1527,243,268 - 27,244,203 (+)Ensemblrn6Rnor6.0
Rnor_5.01531,135,280 - 31,181,360 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41526,137,823 - 26,138,758 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1523,942,351 - 23,943,286 (+)NCBICelera
RGSC_v3.11526,153,522 - 26,154,458 (+)NCBI
Cytogenetic Map15p14NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or11g1
16 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:15
Count of miRNA genes:15
Interacting mature miRNAs:15
Transcripts:ENSRNOT00000046583
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151448116528469888Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)151985656634924750Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
5 4 15 14 12 3 7 3 4 32 20 6 4 31 9

Sequence


Ensembl Acc Id: ENSRNOT00000046583   ⟹   ENSRNOP00000047008
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1527,243,268 - 27,244,203 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097558   ⟹   ENSRNOP00000083819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1523,606,182 - 23,613,804 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109792   ⟹   ENSRNOP00000082689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1523,605,389 - 23,613,804 (+)Ensembl
RefSeq Acc Id: NM_001001003   ⟹   NP_001001003
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,084,355 - 26,085,290 (+)NCBI
mRatBN7.21523,610,778 - 23,611,713 (+)NCBI
Rnor_6.01527,243,268 - 27,244,203 (+)NCBI
Rnor_5.01531,135,280 - 31,181,360 (+)NCBI
RGSC_v3.41526,137,823 - 26,138,758 (+)RGD
Celera1523,942,351 - 23,943,286 (+)RGD
Sequence:
RefSeq Acc Id: XM_006251847   ⟹   XP_006251909
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,067,065 - 26,085,314 (+)NCBI
mRatBN7.21523,600,747 - 23,615,598 (+)NCBI
Rnor_6.01527,233,271 - 27,244,592 (+)NCBI
Rnor_5.01531,135,280 - 31,181,360 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001001003 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251909 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL88406 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000082689.1
  ENSRNOP00000083819.1
RefSeq Acc Id: NP_001001003   ⟸   NM_001001003
- UniProtKB: D4A3K0 (UniProtKB/TrEMBL),   A6KEA1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251909   ⟸   XM_006251847
- Peptide Label: isoform X1
- UniProtKB: D4A3K0 (UniProtKB/TrEMBL),   A6KEA1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000047008   ⟸   ENSRNOT00000046583
Ensembl Acc Id: ENSRNOP00000082689   ⟸   ENSRNOT00000109792
Ensembl Acc Id: ENSRNOP00000083819   ⟸   ENSRNOT00000097558
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3K0-F1-model_v2 AlphaFold D4A3K0 1-311 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333946 AgrOrtholog
BioCyc Gene G2FUF-14081 BioCyc
Ensembl Genes ENSRNOG00000049936 Ensembl
  ENSRNOG00000065218 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000097558.1 UniProtKB/TrEMBL
  ENSRNOT00000109792.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_GPCR1 UniProtKB/TrEMBL
KEGG Report rno:405371 UniProtKB/TrEMBL
NCBI Gene 405371 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or11g1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049936 RatGTEx
  ENSRNOG00000065218 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6KEA1 ENTREZGENE, UniProtKB/TrEMBL
  D4A3K0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or11g1  olfactory receptor family 11 subfamily G member 1  Olr1615  olfactory receptor 1615  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1615  olfactory receptor 1615   Olr1615_predicted  olfactory receptor 1615 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1615_predicted  olfactory receptor 1615 (predicted)      Symbol and Name status set to approved 70820 APPROVED