Mss51 (MSS51 mitochondrial translational activator) - Rat Genome Database

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Gene: Mss51 (MSS51 mitochondrial translational activator) Mus musculus
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Symbol: Mss51
Name: MSS51 mitochondrial translational activator
RGD ID: 1332446
MGI Page MGI
Description: Predicted to enable metal ion binding activity. Orthologous to human MSS51 (MSS51 mitochondrial translational activator).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4833444M15Rik; putative protein MSS51 homolog, mitochondrial; zinc finger MYND domain-containing protein 17; zinc finger, MYND domain containing 17; Zmynd1; Zmynd17
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391420,532,925 - 20,546,969 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1420,532,935 - 20,546,969 (-)EnsemblGRCm39 Ensembl
GRCm381420,482,857 - 20,496,901 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1420,482,867 - 20,496,901 (-)EnsemblGRCm38mm10GRCm38
MGSCv371421,302,086 - 21,316,123 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361419,271,419 - 19,285,453 (-)NCBIMGSCv36mm8
Celera1416,864,286 - 16,878,323 (-)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1411.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21677750   PMID:29913553   PMID:31921843   PMID:33423297   PMID:37002920  


Genomics

Comparative Map Data
Mss51
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391420,532,925 - 20,546,969 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1420,532,935 - 20,546,969 (-)EnsemblGRCm39 Ensembl
GRCm381420,482,857 - 20,496,901 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1420,482,867 - 20,496,901 (-)EnsemblGRCm38mm10GRCm38
MGSCv371421,302,086 - 21,316,123 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361419,271,419 - 19,285,453 (-)NCBIMGSCv36mm8
Celera1416,864,286 - 16,878,323 (-)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1411.53NCBI
MSS51
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381073,423,579 - 73,433,561 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1073,423,579 - 73,433,561 (-)EnsemblGRCh38hg38GRCh38
GRCh371075,183,337 - 75,193,319 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361074,853,343 - 74,863,325 (-)NCBINCBI36Build 36hg18NCBI36
Build 341074,853,344 - 74,863,324NCBI
Celera1068,468,933 - 68,478,915 (-)NCBICelera
Cytogenetic Map10q22.2NCBI
HuRef1069,177,050 - 69,187,032 (-)NCBIHuRef
CHM1_11075,465,098 - 75,475,085 (-)NCBICHM1_1
T2T-CHM13v2.01074,294,994 - 74,304,976 (-)NCBIT2T-CHM13v2.0
Mss51
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8153,855,094 - 3,868,614 (+)NCBIGRCr8
mRatBN7.2153,805,240 - 3,819,385 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl153,807,516 - 3,819,385 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx153,817,674 - 3,829,543 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0155,204,098 - 5,215,967 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0153,816,491 - 3,828,360 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0154,240,203 - 4,252,072 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl154,240,203 - 4,252,072 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0158,341,460 - 8,353,330 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4154,033,660 - 4,045,529 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1154,041,547 - 4,045,564 (+)NCBI
Celera15775,583 - 787,452 (-)NCBICelera
Cytogenetic Map15p16NCBI
Mss51
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543718,380,026 - 18,390,840 (+)NCBIChiLan1.0ChiLan1.0
MSS51
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2885,599,377 - 85,611,239 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11085,601,695 - 85,617,707 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01069,971,015 - 69,983,208 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11072,429,833 - 72,439,963 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1072,429,833 - 72,439,963 (-)Ensemblpanpan1.1panPan2
MSS51
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1423,965,952 - 23,974,053 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl423,966,009 - 23,973,191 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha424,103,748 - 24,111,813 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0424,246,143 - 24,254,198 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl424,246,319 - 24,253,381 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1424,143,664 - 24,151,719 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0424,344,087 - 24,352,117 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0424,699,000 - 24,707,057 (-)NCBIUU_Cfam_GSD_1.0
Mss51
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721357,128,998 - 57,133,471 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365215,617,218 - 5,625,778 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365215,616,325 - 5,625,647 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MSS51
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1476,239,500 - 76,247,672 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11476,239,497 - 76,247,414 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21482,365,033 - 82,375,464 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MSS51
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1957,843,295 - 57,854,142 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl957,849,820 - 57,853,166 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604818,424,693 - 18,436,476 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mss51
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247547,032,550 - 7,042,222 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mss51
299 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:55
Interacting mature miRNAs:56
Transcripts:ENSMUST00000022353
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141550Dbm3_mdiabetes modifier 3 (mouse)Not determined514347339143596Mouse
27226748Femd8_mfemur midshaft diameter 8, 10 week (mouse)141376927346737457Mouse
1300544Hypn_mhyperinsulinemia (mouse)Not determined141516061649160765Mouse
1301991Wta3_mweight adult 3 (mouse)Not determined14388747337887650Mouse
4141864Mrdq4_mmodifier of retinal degeneration QTL 4 (mouse)Not determined992324548765082Mouse
11532711Sluc40_msusceptibility to lung cancer 40 (mouse)14127379943Mouse
1300779Dyscalc4_mdystrophic cardiac calcinosis 4 (mouse)Not determined141221287146213007Mouse
10412071Ssen3_msuseptibility to Sendai virus 3 (mouse)Not determined14126987934Mouse
4141265Appd2_mAPP associated premature death 2 (mouse)Not determined14594555230114862Mouse
27226752Femd4_mfemur midshaft diameter 4, 5 week (mouse)141376927347237457Mouse
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141882760452827726Mouse


Sequence


Ensembl Acc Id: ENSMUST00000022353   ⟹   ENSMUSP00000022353
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1420,532,935 - 20,546,969 (-)Ensembl
GRCm38.p6 Ensembl1420,482,867 - 20,496,901 (-)Ensembl
RefSeq Acc Id: NM_029104   ⟹   NP_083380
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391420,532,932 - 20,546,969 (-)NCBI
GRCm381420,482,864 - 20,496,901 (-)NCBI
MGSCv371421,302,086 - 21,316,123 (-)RGD
Celera1416,864,286 - 16,878,323 (-)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006519636   ⟹   XP_006519699
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391420,532,925 - 20,537,659 (-)NCBI
GRCm381420,482,857 - 20,487,591 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_083380 (Get FASTA)   NCBI Sequence Viewer  
  XP_006519699 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI19774 (Get FASTA)   NCBI Sequence Viewer  
  AAI19817 (Get FASTA)   NCBI Sequence Viewer  
  BAB29556 (Get FASTA)   NCBI Sequence Viewer  
  EDL01509 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000022353
  ENSMUSP00000022353.4
GenBank Protein Q9D5Z5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_083380   ⟸   NM_029104
- UniProtKB: Q0VD61 (UniProtKB/Swiss-Prot),   Q9D5Z5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006519699   ⟸   XM_006519636
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000022353   ⟸   ENSMUST00000022353

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D5Z5-F1-model_v2 AlphaFold Q9D5Z5 1-446 view protein structure

Promoters
RGD ID:6825556
Promoter ID:MM_KWN:15796
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Spleen
Transcripts:NM_029104
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361421,315,664 - 21,316,164 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1922093 AgrOrtholog
Ensembl Genes ENSMUSG00000021815 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000022353 ENTREZGENE
  ENSMUST00000022353.5 UniProtKB/Swiss-Prot
Gene3D-CATH 6.10.140.2220 UniProtKB/Swiss-Prot
InterPro Mito_gene_expr_regulator UniProtKB/Swiss-Prot
  Mss51-like_C UniProtKB/Swiss-Prot
  Znf_MYND UniProtKB/Swiss-Prot
KEGG Report mmu:74843 UniProtKB/Swiss-Prot
MGD MGI:1922093 ENTREZGENE
NCBI Gene 74843 ENTREZGENE
PANTHER PROTEIN MSS51 HOMOLOG, MITOCHONDRIAL-RELATED UniProtKB/Swiss-Prot
  PTHR46920 UniProtKB/Swiss-Prot
Pfam MSS51_C UniProtKB/Swiss-Prot
  zf-MYND UniProtKB/Swiss-Prot
PhenoGen Mss51 PhenoGen
PROSITE ZF_MYND_1 UniProtKB/Swiss-Prot
  ZF_MYND_2 UniProtKB/Swiss-Prot
Superfamily-SCOP HIT/MYND zinc finger-like UniProtKB/Swiss-Prot
UniProt MSS51_MOUSE UniProtKB/Swiss-Prot
  Q0VD61 ENTREZGENE
  Q9D5Z5 ENTREZGENE
UniProt Secondary Q0VD61 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-08 Mss51  MSS51 mitochondrial translational activator  Zmynd17  zinc finger, MYND domain containing 17  Symbol and/or name change 5135510 APPROVED