Fstl1 (follistatin-like 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Fstl1 (follistatin-like 1) Mus musculus
Analyze
Symbol: Fstl1
Name: follistatin-like 1
RGD ID: 1332393
MGI Page MGI
Description: Predicted to enable calcium ion binding activity and heparin binding activity. Involved in endothelial cell differentiation; endothelial cell migration; and negative regulation of apoptotic process. Acts upstream of or within hematopoietic stem cell homeostasis. Located in extracellular space. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; limb; and sensory organ. Used to study pulmonary emphysema. Orthologous to human FSTL1 (follistatin like 1).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: AI316791; AW107808; follistatin-like protein 1; follistatin-related protein 1; Fstl; TGF-beta-inducible protein TSC-36; TSC-3; TSC-36
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391637,597,417 - 37,656,878 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1637,597,235 - 37,656,876 (+)EnsemblGRCm39 Ensembl
GRCm381637,777,055 - 37,836,516 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1637,776,873 - 37,836,514 (+)EnsemblGRCm38mm10GRCm38
MGSCv371637,777,141 - 37,836,602 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361637,696,294 - 37,755,755 (+)NCBIMGSCv36mm8
Celera1638,184,966 - 38,244,699 (+)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1626.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2-butoxyethanol  (EXP)
3,4-dichloroaniline  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
buspirone  (ISO)
cadmium dichloride  (EXP)
calciol  (EXP)
capsaicin  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlordecone  (EXP)
choline  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
clotrimazole  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
Cuprizon  (ISO)
curcumin  (EXP)
cyclosporin A  (ISO)
DDE  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
disodium selenite  (ISO)
disulfiram  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (EXP,ISO)
folic acid  (EXP)
fonofos  (ISO)
fulvestrant  (ISO)
furan  (ISO)
genistein  (EXP)
glycidol  (ISO)
glyphosate  (EXP)
griseofulvin  (EXP)
indometacin  (ISO)
inulin  (EXP)
L-methionine  (EXP)
methimazole  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naproxen  (ISO)
nefazodone  (ISO)
nimesulide  (ISO)
nitrofen  (ISO)
okadaic acid  (EXP)
oxaliplatin  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
parathion  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sumatriptan  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
tetrachloromethane  (EXP,ISO)
thiram  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (EXP)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal action potential  (IAGP)
abnormal breathing pattern  (IAGP)
abnormal bronchiole morphology  (IAGP)
abnormal cervical atlas morphology  (IAGP)
abnormal cervical axis morphology  (IAGP)
abnormal coronary vessel morphology  (IAGP)
abnormal costal cartilage morphology  (IAGP)
abnormal digit morphology  (IAGP)
abnormal dorsal root ganglion morphology  (IAGP)
abnormal heart septum morphology  (IAGP)
abnormal hindlimb stylopod morphology  (IAGP)
abnormal hindlimb zeugopod morphology  (IAGP)
abnormal kidney pelvis morphology  (IAGP)
abnormal larynx morphology  (IAGP)
abnormal lung development  (IAGP)
abnormal lung epithelium morphology  (IAGP)
abnormal lung hysteresivity  (IAGP)
abnormal lung lobe morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal lung volume  (IAGP)
abnormal metacarpal bone morphology  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal pulmonary alveolar sac morphology  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal respiratory system physiology  (IAGP)
abnormal rib morphology  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal spine curvature  (IAGP)
abnormal trachea morphology  (IAGP)
abnormal tracheal cartilage morphology  (IAGP)
abnormal tracheal ciliated epithelium morphology  (IAGP)
abnormal type II pneumocyte morphology  (IAGP)
abnormal ureter development  (IAGP)
abnormal ureter morphology  (IAGP)
abnormal ureter urothelium morphology  (IAGP)
absent patella  (IAGP)
absent sesamoid bone of gastrocnemius  (IAGP)
asymmetric sternocostal joints  (IAGP)
bowed fibula  (IAGP)
camptomelia  (IAGP)
cardiac fibrosis  (IAGP)
cardiac hypertrophy  (IAGP)
cyanosis  (IAGP)
decreased alveolar lamellar body number  (IAGP)
decreased angiogenesis  (IAGP)
decreased bone ossification  (IAGP)
decreased chemical nociceptive threshold  (IAGP)
decreased fasting circulating glucose level  (IEA)
decreased heart left ventricle muscle contractility  (IAGP)
decreased lung elastance  (IAGP)
decreased neutrophil cell number  (IEA)
decreased surfactant secretion  (IAGP)
decreased thermal nociceptive threshold  (IAGP)
decreased tracheal cartilage ring number  (IAGP)
decreased type I pneumocyte number  (IAGP)
dilated ureter  (IAGP)
emphysema  (IAGP)
fused phalanges  (IAGP)
hydronephrosis  (IAGP)
hydroureter  (IAGP)
hyperresponsive to tactile stimuli  (IAGP)
impaired glucose tolerance  (IEA)
increased circulating cholesterol level  (IEA)
increased circulating HDL cholesterol level  (IEA)
increased excitatory postsynaptic current frequency  (IAGP)
increased glycogen level  (IAGP)
increased heart left ventricle size  (IAGP)
increased heart left ventricle weight  (IAGP)
increased heart weight  (IAGP)
increased lung apoptosis  (IAGP)
increased lung compliance  (IAGP)
increased lymphocyte cell number  (IEA)
increased myocardial fiber size  (IAGP)
increased response of heart to induced stress  (IAGP)
increased type II pneumocyte number  (IAGP)
kidney papillary atrophy  (IAGP)
lordokyphosis  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
primary atelectasis  (IAGP)
pulmonary hyperplasia  (IAGP)
pulmonary vascular congestion  (IAGP)
respiratory distress  (IAGP)
small kidney  (IAGP)
trachea stenosis  (IAGP)
ureter stenosis  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Brady KP, etal., Genome Res 1997 Nov;7(11):1085-93.
2. Analysis of genes from inner ear developmental-stage cDNA subtraction reveals molecular regionalization of the otic capsule. Ficker M, etal., Dev Biol 2004 Apr 1;268(1):7-23.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7901004   PMID:7957230   PMID:9774969   PMID:10349636   PMID:10853830   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11845287   PMID:12477932   PMID:12819125  
PMID:12904583   PMID:14610273   PMID:15489334   PMID:15733672   PMID:15741177   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16944957   PMID:16982916   PMID:17030984   PMID:17129766  
PMID:17359964   PMID:18519848   PMID:18653563   PMID:18718903   PMID:18725516   PMID:18799693   PMID:18973680   PMID:19109154   PMID:19595790   PMID:20043993   PMID:20054002   PMID:20176958  
PMID:20530739   PMID:20861081   PMID:21068065   PMID:21205933   PMID:21267068   PMID:21382556   PMID:21482757   PMID:21826198   PMID:21873635   PMID:21899704   PMID:21987816   PMID:22006268  
PMID:22265692   PMID:22485132   PMID:22675198   PMID:23585229   PMID:23612079   PMID:24006456   PMID:24194600   PMID:24282586   PMID:24347831   PMID:24470197   PMID:24641944   PMID:24743592  
PMID:24768929   PMID:24838142   PMID:24952961   PMID:25071081   PMID:25584011   PMID:26355153   PMID:26375005   PMID:26382033   PMID:26721501   PMID:26880577   PMID:27234130   PMID:27234440  
PMID:27355685   PMID:27626380   PMID:28049832   PMID:28361925   PMID:28377613   PMID:28473327   PMID:28495857   PMID:28574994   PMID:28705792   PMID:28765894   PMID:28827394   PMID:29394901  
PMID:29513653   PMID:29916090   PMID:30171878   PMID:30530645   PMID:30635025   PMID:31132382   PMID:31351024   PMID:31539501   PMID:31638229   PMID:31834999   PMID:31847129   PMID:31952198  
PMID:32078339   PMID:32247265   PMID:32325033   PMID:32721453   PMID:33077624   PMID:33105483   PMID:33509151   PMID:33639614   PMID:33709299   PMID:33843447   PMID:33936382   PMID:34067060  
PMID:34076707   PMID:34321999   PMID:34502419   PMID:34813964   PMID:35026647   PMID:35140065   PMID:35367454   PMID:35417710   PMID:35439537   PMID:35483234   PMID:35525270   PMID:36115873  
PMID:36162512   PMID:37219765   PMID:37369969   PMID:37406975   PMID:37584664   PMID:38355793   PMID:38436106  


Genomics

Comparative Map Data
Fstl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391637,597,417 - 37,656,878 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1637,597,235 - 37,656,876 (+)EnsemblGRCm39 Ensembl
GRCm381637,777,055 - 37,836,516 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1637,776,873 - 37,836,514 (+)EnsemblGRCm38mm10GRCm38
MGSCv371637,777,141 - 37,836,602 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361637,696,294 - 37,755,755 (+)NCBIMGSCv36mm8
Celera1638,184,966 - 38,244,699 (+)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1626.48NCBI
FSTL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383120,392,293 - 120,450,992 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3120,392,293 - 120,451,016 (-)EnsemblGRCh38hg38GRCh38
GRCh373120,111,140 - 120,169,839 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363121,595,816 - 121,652,515 (-)NCBINCBI36Build 36hg18NCBI36
Build 343121,595,816 - 121,652,515NCBI
Celera3118,522,464 - 118,579,350 (-)NCBICelera
Cytogenetic Map3q13.33NCBI
HuRef3117,488,896 - 117,545,793 (-)NCBIHuRef
CHM1_13120,076,707 - 120,133,627 (-)NCBICHM1_1
T2T-CHM13v2.03123,111,839 - 123,170,569 (-)NCBIT2T-CHM13v2.0
Fstl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81176,400,870 - 76,454,053 (-)NCBIGRCr8
mRatBN7.21162,895,391 - 62,948,581 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1162,779,783 - 62,948,677 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1171,707,886 - 71,761,075 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01164,370,096 - 64,423,283 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01163,420,096 - 63,473,181 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01165,791,196 - 65,845,721 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1165,782,567 - 65,845,418 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01168,884,410 - 68,938,352 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41164,681,814 - 64,735,673 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11164,739,417 - 64,793,262 (-)NCBI
Celera1162,393,441 - 62,446,724 (-)NCBICelera
Cytogenetic Map11q21NCBI
Fstl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542719,952,853 - 20,004,241 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542719,952,823 - 20,003,832 (-)NCBIChiLan1.0ChiLan1.0
FSTL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22118,363,612 - 118,419,277 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13118,368,390 - 118,423,861 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03117,508,772 - 117,564,254 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1 Ensembl3124,422,968 - 124,475,431 (-)Ensemblpanpan1.1panPan2
FSTL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13323,892,317 - 23,914,406 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3323,894,573 - 23,933,779 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3323,919,531 - 23,972,261 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03324,129,955 - 24,182,735 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3324,129,947 - 24,183,502 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13323,930,929 - 23,983,640 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03323,971,619 - 24,024,230 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03324,535,350 - 24,588,071 (-)NCBIUU_Cfam_GSD_1.0
Fstl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602130,335,041 - 130,388,800 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365367,126,966 - 7,187,269 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365367,132,369 - 7,186,951 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FSTL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13139,847,438 - 139,901,965 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113139,847,246 - 139,901,972 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FSTL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12260,371,309 - 60,427,259 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2260,371,554 - 60,428,764 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041105,887,988 - 105,942,526 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fstl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473127,790,363 - 27,841,251 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473127,789,671 - 27,839,267 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fstl1
1776 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1607
Count of miRNA genes:760
Interacting mature miRNAs:982
Transcripts:ENSMUST00000114763, ENSMUST00000123077, ENSMUST00000125279, ENSMUST00000127495, ENSMUST00000135668, ENSMUST00000152579
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11059560Lmr12b_mleishmaniasis resistance 12b (mouse)162879281362792952Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
1302096Aod1a_mautoimmune ovarian dysgenesis 1a (mouse)Not determined163544664392573008Mouse
4141179Ipng3_mimprinted postnatal growth 3 (mouse)Not determined2277525257594076Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
11049571Lmr12c_mleishmaniasis resistance 12c (mouse)162879281362792952Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
11059559Lmr12a_mleishmaniasis resistance 12a (mouse)162879281362792952Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16464631438646414Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined16988163143881631Mouse
4142187Arrd3_mage-related retinal degeneration 3 (mouse)Not determined3252290965466552Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162001932985600826Mouse
26884416Bzwq5_mbi-zygomatic width QTL 5, 5 week (mouse)163732036284696888Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16577525239775440Mouse
1301070Cypr1_mcytokine production 1 (mouse)Not determined163231279566312933Mouse
1300915Lmr12_mleishmaniasis resistance 12 (mouse)Not determined162879281362792952Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16577525239775440Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161552290949523112Mouse
1300534Bmd15_mbone mineral density 15 (mouse)Not determined162193838355938574Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16822605242226052Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16577525239775440Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16577525239775440Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161480292148803032Mouse
15092062Egrme4_mearly growth rate, maternal effect 4 (mouse)162521866444220250Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
10412263Gvhd6_mgraft-versus host disease 6 (mouse)Not determined163606085745511148Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse

Markers in Region
Fstl1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B3UniSTS
cM Map1627.3UniSTS
RH136117  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381637,835,044 - 37,835,239UniSTSGRCm38
MGSCv371637,835,130 - 37,835,325UniSTSGRCm37
Celera1638,243,227 - 38,243,422UniSTS
Cytogenetic Map16B3UniSTS
cM Map1627.3UniSTS
AW107808  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381637,835,552 - 37,835,649UniSTSGRCm38
MGSCv371637,835,638 - 37,835,735UniSTSGRCm37
Celera1638,243,735 - 38,243,832UniSTS
Cytogenetic Map16B3UniSTS
cM Map1627.3UniSTS
Whitehead/MRC_RH16364.68UniSTS
24.MMHAP33FLH3.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381637,834,200 - 37,834,359UniSTSGRCm38
MGSCv371637,834,286 - 37,834,445UniSTSGRCm37
Celera1638,242,383 - 38,242,542UniSTS
Cytogenetic Map16B3UniSTS
cM Map1627.3UniSTS
Whitehead/MRC_RH16366.28UniSTS
UniSTS:224760  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381637,826,666 - 37,826,862UniSTSGRCm38
MGSCv371637,826,752 - 37,826,948UniSTSGRCm37
Celera1638,234,849 - 38,235,045UniSTS
Cytogenetic Map16B3UniSTS
cM Map1627.3UniSTS
Fstl  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381637,835,152 - 37,835,322UniSTSGRCm38
MGSCv371637,835,238 - 37,835,408UniSTSGRCm37
Celera1638,243,335 - 38,243,505UniSTS
Cytogenetic Map16B3UniSTS
cM Map1627.3UniSTS
Fstl1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000114763   ⟹   ENSMUSP00000110411
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1637,597,235 - 37,656,876 (+)Ensembl
GRCm38.p6 Ensembl1637,776,873 - 37,836,514 (+)Ensembl
Ensembl Acc Id: ENSMUST00000123077
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1637,643,064 - 37,655,986 (+)Ensembl
GRCm38.p6 Ensembl1637,822,702 - 37,835,624 (+)Ensembl
Ensembl Acc Id: ENSMUST00000125279
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1637,597,437 - 37,614,600 (+)Ensembl
GRCm38.p6 Ensembl1637,777,075 - 37,794,238 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127495
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1637,636,068 - 37,654,788 (+)Ensembl
GRCm38.p6 Ensembl1637,815,706 - 37,834,426 (+)Ensembl
Ensembl Acc Id: ENSMUST00000135668
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1637,597,514 - 37,639,304 (+)Ensembl
GRCm38.p6 Ensembl1637,777,152 - 37,818,942 (+)Ensembl
Ensembl Acc Id: ENSMUST00000152579
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1637,597,417 - 37,619,833 (+)Ensembl
GRCm38.p6 Ensembl1637,777,055 - 37,799,471 (+)Ensembl
RefSeq Acc Id: NM_008047   ⟹   NP_032073
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391637,597,417 - 37,656,878 (+)NCBI
GRCm381637,777,055 - 37,836,516 (+)ENTREZGENE
MGSCv371637,777,141 - 37,836,602 (+)RGD
Celera1638,184,966 - 38,244,699 (+)RGD
cM Map16 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_032073 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC37633 (Get FASTA)   NCBI Sequence Viewer  
  AAH28921 (Get FASTA)   NCBI Sequence Viewer  
  BAC33751 (Get FASTA)   NCBI Sequence Viewer  
  BAE27689 (Get FASTA)   NCBI Sequence Viewer  
  EDK97964 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000110411
  ENSMUSP00000110411.3
GenBank Protein Q62356 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_032073   ⟸   NM_008047
- Peptide Label: precursor
- UniProtKB: Q6GTX2 (UniProtKB/Swiss-Prot),   Q99JI9 (UniProtKB/Swiss-Prot),   Q62356 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000110411   ⟸   ENSMUST00000114763
Protein Domains
EF-hand   Follistatin-like   Kazal-like   VWFC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62356-F1-model_v2 AlphaFold Q62356 1-306 view protein structure

Promoters
RGD ID:6827053
Promoter ID:MM_KWN:20951
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   ES_Cell,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000063330,   OTTMUST00000063331,   OTTMUST00000063332,   OTTMUST00000064112
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361637,777,001 - 37,777,501 (+)MPROMDB
RGD ID:8686168
Promoter ID:EPDNEW_M21115
Type:initiation region
Name:Fstl1_1
Description:Mus musculus follistatin-like 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381637,777,057 - 37,777,117EPDNEW
RGD ID:6827054
Promoter ID:MM_KWN:20953
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day4,   Brain,   Kidney,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000023511
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361637,813,546 - 37,814,717 (+)MPROMDB
RGD ID:6827055
Promoter ID:MM_KWN:20954
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000063333
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361637,814,921 - 37,815,627 (+)MPROMDB
RGD ID:6827056
Promoter ID:MM_KWN:20955
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000063334
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361637,822,026 - 37,823,287 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:102793 AgrOrtholog
Ensembl Genes ENSMUSG00000022816 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000114763 ENTREZGENE
  ENSMUST00000114763.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.60.30 UniProtKB/Swiss-Prot
  EF-hand UniProtKB/Swiss-Prot
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
  Fol_N UniProtKB/Swiss-Prot
  Follistatin/Osteonectin_EGF UniProtKB/Swiss-Prot
  Kazal_dom UniProtKB/Swiss-Prot
  Kazal_dom_sf UniProtKB/Swiss-Prot
  Prot_Inhib_GrowthFact_Antg UniProtKB/Swiss-Prot
KEGG Report mmu:14314 UniProtKB/Swiss-Prot
MGD MGI:102793 ENTREZGENE
NCBI Gene 14314 ENTREZGENE
PANTHER FOLLISTATIN-RELATED UniProtKB/Swiss-Prot
  FOLLISTATIN-RELATED PROTEIN 1 UniProtKB/Swiss-Prot
Pfam FOLN UniProtKB/Swiss-Prot
  Kazal_2 UniProtKB/Swiss-Prot
PhenoGen Fstl1 PhenoGen
PROSITE EF_HAND_2 UniProtKB/Swiss-Prot
  KAZAL_2 UniProtKB/Swiss-Prot
SMART FOLN UniProtKB/Swiss-Prot
  KAZAL UniProtKB/Swiss-Prot
Superfamily-SCOP FnI-like domain UniProtKB/Swiss-Prot
  SSF100895 UniProtKB/Swiss-Prot
  SSF47473 UniProtKB/Swiss-Prot
UniProt FSTL1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q6GTX2 ENTREZGENE
  Q99JI9 ENTREZGENE
UniProt Secondary Q6GTX2 UniProtKB/Swiss-Prot
  Q99JI9 UniProtKB/Swiss-Prot