Tmem163 (transmembrane protein 163) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Tmem163 (transmembrane protein 163) Mus musculus
Analyze
Symbol: Tmem163
Name: transmembrane protein 163
RGD ID: 1332328
MGI Page MGI
Description: Predicted to enable zinc ion binding activity. Predicted to be involved in myelination; zinc export across plasma membrane; and zinc ion import into synaptic vesicle. Located in synaptic vesicle membrane. Is active in intracellular vesicle and plasma membrane. Is expressed in cerebral cortex; cortical layer V; cortical subplate; heart; and limb. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 25. Orthologous to human TMEM163 (transmembrane protein 163).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2610024A01Rik; A-c; A-cre; Act-C; Act-Cre; actin; actin-cre; beta-actin-cre; cre; SV; SV31; synaptic vesicle membrane protein of 31 kDa; Tg(ACTB-cre)2Mrt; TgN(ACTB-cre)2Mrt
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391127,418,079 - 127,605,758 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1127,414,283 - 127,607,285 (-)EnsemblGRCm39 Ensembl
GRCm381127,490,342 - 127,678,021 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1127,486,546 - 127,679,548 (-)EnsemblGRCm38mm10GRCm38
MGSCv371129,386,919 - 129,574,598 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361129,314,097 - 129,505,567 (-)NCBIMGSCv36mm8
Celera1130,139,903 - 130,318,056 (-)NCBICelera
Cytogenetic Map1E3NCBI
cM Map155.77NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (EXP)
(S)-nicotine  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (ISO)
amphetamine  (ISO)
antirheumatic drug  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cefaloridine  (ISO)
choline  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cylindrospermopsin  (ISO)
diarsenic trioxide  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (ISO)
genistein  (EXP)
indole-3-methanol  (ISO)
L-methionine  (EXP)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
morphine  (EXP)
nicotine  (EXP)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
potassium bromate  (ISO)
progesterone  (ISO)
SB 431542  (ISO)
sodium dichromate  (ISO)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
protein binding  (IPI)
zinc ion binding  (IBA,ISO,ISS)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anogenital distance  (IAGP)
abnormal axon morphology  (IAGP)
abnormal bone structure  (IEA)
abnormal brain development  (IAGP)
abnormal brain interneuron morphology  (IAGP)
abnormal branching of the mammary ductal tree  (IAGP)
abnormal breathing pattern  (IAGP)
abnormal cardiac outflow tract development  (IAGP)
abnormal cartilage development  (IAGP)
abnormal cartilage morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal chiasmata formation  (IAGP)
abnormal circadian behavior  (IAGP)
abnormal coat/hair pigmentation  (IEA)
abnormal deltoid tuberosity morphology  (IAGP)
abnormal external male genitalia morphology  (IAGP)
abnormal eye morphology  (IAGP)
abnormal fat cell morphology  (IAGP)
abnormal female meiosis  (IAGP)
abnormal female reproductive system morphology  (IAGP)
abnormal forebrain morphology  (IAGP)
abnormal forelimb morphology  (IAGP)
abnormal granulosa cell morphology  (IAGP)
abnormal habituation to a new environment  (IAGP)
abnormal head development  (IAGP)
abnormal heart echocardiography feature  (IAGP)
abnormal hindbrain morphology  (IAGP)
abnormal humerus morphology  (IAGP)
abnormal kidney morphology  (IEA)
abnormal lactation  (IAGP)
abnormal long bone epiphyseal plate morphology  (IAGP)
abnormal long bone epiphyseal plate proliferative zone  (IAGP)
abnormal long bone metaphysis morphology  (IAGP)
abnormal male reproductive system morphology  (IAGP)
abnormal mammary gland morphology  (IAGP)
abnormal myometrium morphology  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal nursing  (IAGP)
abnormal oocyte morphology  (IAGP)
abnormal ovary morphology  (IAGP)
abnormal oxygen consumption  (IAGP)
abnormal paranodal axoglial junction morphology  (IAGP)
abnormal paranode morphology  (IAGP)
abnormal placenta labyrinth morphology  (IAGP)
abnormal placenta morphology  (IAGP)
abnormal platelet physiology  (IAGP)
abnormal polar body morphology  (IAGP)
abnormal prostate gland branching morphogenesis  (IAGP)
abnormal prostate gland physiology  (IAGP)
abnormal reproductive system physiology  (IAGP)
abnormal rib morphology  (IAGP)
abnormal right subclavian artery morphology  (IAGP)
abnormal scapula morphology  (IAGP)
abnormal scrotum morphology  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal Sertoli cell morphology  (IAGP)
abnormal skeleton development  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal skin morphology  (IEA)
abnormal somite development  (IAGP)
abnormal spermatocyte morphology  (IAGP)
abnormal spermatogonia morphology  (IAGP)
abnormal spongiotrophoblast layer morphology  (IAGP)
abnormal stellate ganglion morphology  (IAGP)
abnormal striatum morphology  (IAGP)
abnormal tail development  (IAGP)
abnormal telencephalon development  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal vertebrae morphology  (IAGP)
abnormal vitreous body morphology  (IAGP)
absent choroid plexus  (IAGP)
absent corpus luteum  (IAGP)
absent epididymis  (IAGP)
absent external male genitalia  (IAGP)
absent eye anterior chamber  (IAGP)
absent head fold  (IAGP)
absent prostate gland  (IAGP)
absent sclerotome  (IAGP)
absent seminal vesicle  (IAGP)
absent somites  (IAGP)
absent spleen  (IAGP)
absent vas deferens  (IAGP)
arrest of male meiosis  (IAGP)
arrest of spermatogenesis  (IAGP)
asymmetric snout  (IAGP)
belly spot  (IAGP)
blepharoptosis  (IAGP)
broad snout  (IAGP)
cardiac hypertrophy  (IAGP)
cataract  (IAGP)
cleft palate  (IAGP)
coloboma  (IAGP)
cornea vascularization  (IAGP)
cryptorchism  (IAGP)
decreased adiponectin level  (IAGP)
decreased anxiety-related response  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral content  (IEA)
decreased bone mineral density  (IEA)
decreased circulating testosterone level  (IAGP)
decreased cranial neural crest cell number  (IAGP)
decreased embryo size  (IAGP)
decreased forebrain size  (IAGP)
decreased heart rate  (IAGP)
decreased lean body mass  (IEA)
decreased litter size  (IAGP)
decreased locomotor activity  (IAGP)
decreased male germ cell number  (IAGP)
decreased melanocyte number  (IAGP)
decreased ovary weight  (IAGP)
decreased oviduct weight  (IAGP)
decreased platelet aggregation  (IAGP)
decreased platelet dense granule number  (IAGP)
decreased prepulse inhibition  (IAGP)
decreased primary ovarian follicle number  (IAGP)
decreased primordial ovarian follicle number  (IAGP)
decreased response to leptin  (IAGP)
decreased somite size  (IAGP)
decreased startle reflex  (IAGP)
decreased testis weight  (IAGP)
decreased uterus weight  (IAGP)
decreased width of hypertrophic chondrocyte zone  (IAGP)
disorganized long bone epiphyseal plate  (IAGP)
distended abdomen  (IAGP)
domed cranium  (IAGP)
double outlet right ventricle  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality between implantation and placentation, complete penetrance  (IAGP)
embryonic lethality between somite formation and embryo turning, complete penetrance  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality prior to tooth bud stage  (IAGP)
embryonic lethality prior to tooth bud stage, complete penetrance  (IAGP)
embryonic lethality, incomplete penetrance  (IAGP)
enhanced contextual conditioning behavior  (IAGP)
enhanced long-term potentiation  (IAGP)
enhanced NMDA-mediated synaptic currents  (IAGP)
enlarged thymus  (IAGP)
exencephaly  (IAGP)
eye hemorrhage  (IEA)
female infertility  (IAGP)
hydrocephaly  (IAGP)
hyperglycemia  (IAGP)
hypopnea  (IAGP)
hypospadia  (IAGP)
impaired glucose tolerance  (IAGP)
impaired ovarian folliculogenesis  (IAGP)
impaired spatial learning  (IAGP)
increased atretic ovarian follicle number  (IAGP)
increased bleeding time  (IAGP)
increased bone ossification  (IAGP)
increased circulating glucose level  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating leptin level  (IAGP)
increased circulating testosterone level  (IAGP)
increased circulating triglyceride level  (IAGP)
increased cranial neural crest cell apoptosis  (IAGP)
increased exploration in new environment  (IAGP)
increased gonadal fat pad weight  (IAGP)
increased liver triglyceride level  (IAGP)
increased locomotor activity  (IAGP)
increased male germ cell apoptosis  (IAGP)
increased osteoclast cell number  (IAGP)
increased prepulse inhibition  (IAGP)
increased pulmonary ventilation  (IAGP)
increased renal fat pad weight  (IAGP)
increased skeletal muscle triglyceride level  (IAGP)
increased susceptibility to induced morbidity/mortality  (IAGP)
increased susceptibility to weight gain  (IAGP)
increased tidal volume  (IAGP)
increased total body fat amount  (IAGP)
increased trophoblast giant cell number  (IAGP)
increased white adipose tissue amount  (IAGP)
insulin resistance  (IAGP)
kinked neural tube  (IAGP)
kinked tail  (IAGP)
kyphosis  (IAGP)
Leydig cell hypertrophy  (IAGP)
male infertility  (IAGP)
maternal effect  (IAGP)
meiotic nondisjunction during M1 phase  (IAGP)
microphthalmia  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
obese  (IAGP)
oligozoospermia  (IAGP)
open neural tube  (IAGP)
ovary cyst  (IAGP)
overriding aortic valve  (IAGP)
perimembraneous ventricular septal defect  (IAGP)
perinatal lethality  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
premature endochondral bone ossification  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
protruding tongue  (IAGP)
respiratory failure  (IAGP)
retina fold  (IAGP)
rib fusion  (IAGP)
scapular bone hypoplasia  (IAGP)
seizures  (IAGP)
seminiferous tubule degeneration  (IAGP)
short mandible  (IAGP)
short ribs  (IAGP)
short snout  (IAGP)
small kidney  (IEA)
small penis  (IAGP)
small seminiferous tubules  (IAGP)
small testis  (IAGP)
small thoracic cavity  (IAGP)
testicular atrophy  (IAGP)
testis hypoplasia  (IAGP)
thin placenta labyrinth  (IAGP)
tremors  (IAGP)
uterus hypoplasia  (IAGP)
vagina hypoplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9326948   PMID:9462741   PMID:9500544   PMID:9598348   PMID:9630749   PMID:10349636   PMID:10675330   PMID:10841580   PMID:11035038   PMID:11042159   PMID:11076861  
PMID:11125038   PMID:11217851   PMID:11299042   PMID:11316774   PMID:11748145   PMID:11820816   PMID:11839815   PMID:12086874   PMID:12206900   PMID:12370412   PMID:12466851   PMID:12477932  
PMID:12629040   PMID:12724423   PMID:12756187   PMID:12859898   PMID:12879071   PMID:12923530   PMID:14563324   PMID:14614856   PMID:14657014   PMID:14676301   PMID:14690613   PMID:15013800  
PMID:15030770   PMID:15060168   PMID:15075292   PMID:15085193   PMID:15153557   PMID:15223342   PMID:15247919   PMID:15345243   PMID:15469971   PMID:15489334   PMID:15539485   PMID:15691764  
PMID:15789424   PMID:15798219   PMID:15809037   PMID:15831469   PMID:15882628   PMID:15899843   PMID:15919793   PMID:15975937   PMID:16055716   PMID:16141072   PMID:16141073   PMID:16251442  
PMID:16284245   PMID:16287843   PMID:16403804   PMID:16424220   PMID:16452092   PMID:16602821   PMID:16630833   PMID:16651659   PMID:16788063   PMID:16790481   PMID:16790550   PMID:16809763  
PMID:16855091   PMID:16869764   PMID:16870172   PMID:16890158   PMID:16936073   PMID:16982677   PMID:16982684   PMID:16991118   PMID:17005861   PMID:17050626   PMID:17065462   PMID:17095600  
PMID:17114649   PMID:17142319   PMID:17202188   PMID:17242199   PMID:17266131   PMID:17272508   PMID:17312021   PMID:17360456   PMID:17360769   PMID:17470285   PMID:17537792   PMID:17623043  
PMID:17662942   PMID:17676633   PMID:17713536   PMID:17901218   PMID:17906629   PMID:17927825   PMID:18033766   PMID:18182616   PMID:18202285   PMID:18263604   PMID:18305247   PMID:18316482  
PMID:18329372   PMID:18414682   PMID:18417692   PMID:18663357   PMID:18667607   PMID:18755802   PMID:18953638   PMID:19008461   PMID:19029044   PMID:19029045   PMID:19074010   PMID:19093031  
PMID:19129496   PMID:19155299   PMID:19164450   PMID:19204372   PMID:19252479   PMID:19356719   PMID:19359471   PMID:19380807   PMID:19401562   PMID:19414555   PMID:19679071   PMID:19726871  
PMID:19774080   PMID:19776259   PMID:19805323   PMID:19907077   PMID:19940926   PMID:20059951   PMID:20371806   PMID:20412777   PMID:20463034   PMID:20559429   PMID:20841500   PMID:20848592  
PMID:21098273   PMID:21303853   PMID:21308854   PMID:21362415   PMID:21364967   PMID:21368173   PMID:21397594   PMID:21436583   PMID:21445260   PMID:21455723   PMID:21512031   PMID:21555557  
PMID:21606958   PMID:21632923   PMID:21655085   PMID:21666053   PMID:21677750   PMID:21689597   PMID:21763481   PMID:21764747   PMID:21768369   PMID:21798952   PMID:21871565   PMID:21873635  
PMID:21909376   PMID:21921034   PMID:22056359   PMID:22062772   PMID:22069040   PMID:22082664   PMID:22099461   PMID:22233545   PMID:22275881   PMID:22307631   PMID:22315402   PMID:22355113  
PMID:22363783   PMID:22492029   PMID:22560297   PMID:22627285   PMID:22674535   PMID:22678057   PMID:22697126   PMID:22709692   PMID:22719950   PMID:22730198   PMID:22815849   PMID:22819676  
PMID:22863743   PMID:22878961   PMID:22912418   PMID:22912798   PMID:23023002   PMID:23041626   PMID:23095280   PMID:23229899   PMID:23269247   PMID:23312518   PMID:23355744   PMID:23415800  
PMID:23418536   PMID:23516300   PMID:23530049   PMID:23542432   PMID:23577141   PMID:23673330   PMID:23677977   PMID:23748361   PMID:23754746   PMID:23811236   PMID:23852112   PMID:23873027  
PMID:24107967   PMID:24124870   PMID:24167280   PMID:24189070   PMID:24227709   PMID:24247431   PMID:24312475   PMID:24381199   PMID:24514266   PMID:24516400   PMID:24589777   PMID:24595293  
PMID:24598388   PMID:24627527   PMID:24664281   PMID:24748541   PMID:24802190   PMID:24847848   PMID:24876275   PMID:24931605   PMID:24931609   PMID:24956260   PMID:24956378   PMID:24997765  
PMID:25028484   PMID:25073978   PMID:25083865   PMID:25126785   PMID:25130899   PMID:25183173   PMID:25201955   PMID:25251415   PMID:25263330   PMID:25267913   PMID:25383540   PMID:25497093  
PMID:25503409   PMID:25526089   PMID:25742748   PMID:25762440   PMID:25805134   PMID:25855173   PMID:26000481   PMID:26017770   PMID:26097038   PMID:26162102   PMID:26166575   PMID:26173091  
PMID:26255629   PMID:26385750   PMID:26386426   PMID:26546974   PMID:26586220   PMID:26655900   PMID:26715742   PMID:26746789   PMID:26746790   PMID:26843644   PMID:26850657   PMID:26888934  
PMID:26932671   PMID:27006499   PMID:27006501   PMID:27019112   PMID:27025239   PMID:27053202   PMID:27147518   PMID:27264177   PMID:27273096   PMID:27441631   PMID:27479497   PMID:27631493  
PMID:28053125   PMID:28148727   PMID:28158249   PMID:28166224   PMID:28424158   PMID:28511845   PMID:28536097   PMID:28607062   PMID:28625779   PMID:28655792   PMID:28706256   PMID:28723571  
PMID:28800946   PMID:28839205   PMID:28886341   PMID:29016745   PMID:29030458   PMID:29068314   PMID:29073114   PMID:29191918   PMID:29213092   PMID:29222403   PMID:29222434   PMID:29229773  
PMID:29229982   PMID:29293958   PMID:29401310   PMID:29579167   PMID:29666270   PMID:29668850   PMID:29961578   PMID:30135513   PMID:30190546   PMID:30251381   PMID:30305289   PMID:30344048  
PMID:30447021   PMID:30673615   PMID:30765420   PMID:30846611   PMID:30887000   PMID:30926782   PMID:30926797   PMID:31051113   PMID:31218818   PMID:31451639   PMID:31480771   PMID:31484989  
PMID:31513564   PMID:31520742   PMID:31539519   PMID:31626642   PMID:31640562   PMID:31653568   PMID:31722069   PMID:31813547   PMID:31980536   PMID:32015540   PMID:32065256   PMID:32092051  
PMID:32442405   PMID:32492420   PMID:32515350   PMID:32516589   PMID:32566252   PMID:32644214   PMID:32649884   PMID:32657535   PMID:32692983   PMID:32765228   PMID:32822210   PMID:32883883  
PMID:32969477   PMID:33030203   PMID:33238123   PMID:33513603   PMID:33515576   PMID:33831348   PMID:33958373   PMID:34050709   PMID:34272903   PMID:34398873   PMID:34433040   PMID:34434167  
PMID:34463714   PMID:34499868   PMID:34504306   PMID:34516839   PMID:34762332   PMID:34893605   PMID:34910909   PMID:34931676   PMID:34932949   PMID:34977916   PMID:35081489   PMID:35090878  
PMID:35115729   PMID:35131866   PMID:35236989   PMID:35535852   PMID:35536884   PMID:35593225   PMID:35745101   PMID:35784651   PMID:35797824   PMID:35973480   PMID:36332029   PMID:36343245  
PMID:36535370   PMID:36584300   PMID:36608143   PMID:36717164   PMID:36793209   PMID:37098137   PMID:37126510   PMID:37167859   PMID:37261951   PMID:37311583   PMID:37332102   PMID:37831760  
PMID:37901434   PMID:37956053   PMID:38290089   PMID:38355793   PMID:38526616   PMID:38717426  


Genomics

Comparative Map Data
Tmem163
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391127,418,079 - 127,605,758 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1127,414,283 - 127,607,285 (-)EnsemblGRCm39 Ensembl
GRCm381127,490,342 - 127,678,021 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1127,486,546 - 127,679,548 (-)EnsemblGRCm38mm10GRCm38
MGSCv371129,386,919 - 129,574,598 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361129,314,097 - 129,505,567 (-)NCBIMGSCv36mm8
Celera1130,139,903 - 130,318,056 (-)NCBICelera
Cytogenetic Map1E3NCBI
cM Map155.77NCBI
TMEM163
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382134,455,759 - 134,719,000 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2134,455,759 - 134,719,000 (-)EnsemblGRCh38hg38GRCh38
GRCh372135,213,330 - 135,476,570 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362134,930,030 - 135,193,040 (-)NCBINCBI36Build 36hg18NCBI36
Celera2128,926,002 - 129,189,469 (-)NCBICelera
Cytogenetic Map2q21.3NCBI
HuRef2127,206,130 - 127,468,192 (-)NCBIHuRef
CHM1_12135,217,959 - 135,481,287 (-)NCBICHM1_1
T2T-CHM13v2.02134,895,326 - 135,159,268 (-)NCBIT2T-CHM13v2.0
Tmem163
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81341,520,595 - 41,693,938 (-)NCBIGRCr8
mRatBN7.21338,967,913 - 39,141,664 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1338,968,101 - 39,141,452 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1341,550,247 - 41,724,197 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01342,838,349 - 43,012,290 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01340,104,163 - 40,278,089 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01344,166,306 - 44,345,735 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1344,166,306 - 44,345,735 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01349,258,672 - 49,433,018 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41340,144,073 - 40,327,947 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11340,158,648 - 40,363,296 (-)NCBI
Celera1339,345,427 - 39,519,218 (-)NCBICelera
Cytogenetic Map13q13NCBI
Tmem163
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554402,007,097 - 2,240,275 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554402,006,152 - 2,240,209 (-)NCBIChiLan1.0ChiLan1.0
TMEM163
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21340,207,253 - 40,464,519 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B40,222,232 - 40,479,489 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B25,138,333 - 25,393,295 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B138,545,761 - 138,793,811 (-)NCBIpanpan1.1PanPan1.1panPan2
TMEM163
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11937,335,608 - 37,744,291 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1937,336,598 - 37,562,509 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1937,576,037 - 37,799,910 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01938,780,404 - 39,005,058 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1938,780,415 - 39,039,513 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11937,423,032 - 37,647,603 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01937,583,925 - 37,808,428 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01938,812,101 - 39,036,892 (-)NCBIUU_Cfam_GSD_1.0
Tmem163
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530383,520,586 - 83,735,621 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493646957,882,130 - 58,097,965 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM163
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1517,262,138 - 17,543,398 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11517,260,885 - 17,548,920 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21519,811,516 - 20,021,754 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM163
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11018,692,742 - 18,950,099 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660613,553,990 - 3,812,202 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem163
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473233,904,224 - 34,143,441 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473233,903,263 - 34,143,635 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tmem163
6868 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1126
Count of miRNA genes:511
Interacting mature miRNAs:611
Transcripts:ENSMUST00000027585, ENSMUST00000160111, ENSMUST00000160616, ENSMUST00000162406
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118099720152099816Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174991977133290937Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195527725162027569Mouse
27226714Metcl1_mmetatarsal-calcaneal length 1, 5 week (mouse)1121727729139727738Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1301979Melm1_mmelanoma modifier 1 (mouse)Not determined1109638262143638479Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112008822168186402Mouse
1301123Cd8mts2_mCD8 memory T cell subset 2 (mouse)Not determined196618386130618557Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121727729164827569Mouse
12790994Aaaq1_maortic arch angle QTL 1 (mouse)1109495943143495943Mouse
10045640Jckm4_mjuvenile cystic kidney modifier 4 (mouse)Not determined1116290836150290937Mouse
1301249Sbw1_msplenomegaly-NZB x NZW 1 (mouse)Not determined1112131005146131085Mouse
1301193Lxw3_mlupus BXSB x NZW 3 (mouse)Not determined1102968534136968667Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1122927738156927738Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
27095931Pglq1_mpelvic girdle length QTL 1, 5 week (mouse)175976637128527737Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121727729153875746Mouse
1301753Tir3a_mtrypansomiasis infection response 3a (mouse)Not determined197053986131054190Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182643189135615379Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121727729153775746Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122027729164827569Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167339159129727737Mouse
1301536Pbbcp1_mperipheral blood B cell percentage 1 (mouse)Not determined199507660133507845Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194127725148775742Mouse
1357600Obq17_mobesity QTL 17 (mouse)Not determined1110553179144553298Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
10401248Bglu12_mblood glucose level 12 (mouse)Not determined1110553179144553298Mouse

Markers in Region
28.MHAa65T_M13Rev.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381127,582,163 - 127,582,315UniSTSGRCm38
MGSCv371129,478,740 - 129,478,892UniSTSGRCm37
Celera1130,223,469 - 130,223,621UniSTS
Cytogenetic Map1E3UniSTS
Whitehead_YAC1 UniSTS
D1Mit495  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381127,625,442 - 127,625,561UniSTSGRCm38
MGSCv371129,522,019 - 129,522,138UniSTSGRCm37
Celera1130,263,762 - 130,263,875UniSTS
Cytogenetic Map1E3UniSTS
cM Map167.0UniSTS
Whitehead Genetic169.9UniSTS
Whitehead/MRC_RH11691.96UniSTS
Whitehead_YAC1 UniSTS


Sequence


Ensembl Acc Id: ENSMUST00000027585   ⟹   ENSMUSP00000027585
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1127,414,283 - 127,605,833 (-)Ensembl
GRCm38.p6 Ensembl1127,486,546 - 127,678,096 (-)Ensembl
Ensembl Acc Id: ENSMUST00000160111
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1127,419,098 - 127,428,081 (-)Ensembl
GRCm38.p6 Ensembl1127,491,361 - 127,500,344 (-)Ensembl
Ensembl Acc Id: ENSMUST00000160616   ⟹   ENSMUSP00000124307
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1127,414,295 - 127,605,758 (-)Ensembl
GRCm38.p6 Ensembl1127,486,558 - 127,678,021 (-)Ensembl
Ensembl Acc Id: ENSMUST00000162406
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1127,419,282 - 127,465,167 (-)Ensembl
GRCm38.p6 Ensembl1127,491,545 - 127,537,430 (-)Ensembl
Ensembl Acc Id: ENSMUST00000185560   ⟹   ENSMUSP00000140828
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1127,418,635 - 127,607,285 (-)Ensembl
GRCm38.p6 Ensembl1127,490,898 - 127,679,548 (-)Ensembl
RefSeq Acc Id: NM_028135   ⟹   NP_082411
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391127,418,079 - 127,605,758 (-)NCBI
GRCm381127,490,342 - 127,678,021 (-)NCBI
MGSCv371129,386,919 - 129,574,598 (-)RGD
Celera1130,139,903 - 130,318,056 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_082411   ⟸   NM_028135
- UniProtKB: Q8C8I2 (UniProtKB/Swiss-Prot),   Q9D0E0 (UniProtKB/Swiss-Prot),   Q8C996 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000027585   ⟸   ENSMUST00000027585
Ensembl Acc Id: ENSMUSP00000140828   ⟸   ENSMUST00000185560
Ensembl Acc Id: ENSMUSP00000124307   ⟸   ENSMUST00000160616

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C996-F1-model_v2 AlphaFold Q8C996 1-288 view protein structure

Promoters
RGD ID:6874788
Promoter ID:EPDNEW_M839
Type:multiple initiation site
Name:Tmem163_1
Description:Mus musculus transmembrane protein 163 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M840  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381127,677,762 - 127,677,822EPDNEW
RGD ID:6874778
Promoter ID:EPDNEW_M840
Type:initiation region
Name:Tmem163_2
Description:Mus musculus transmembrane protein 163 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M839  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381127,677,940 - 127,678,000EPDNEW
RGD ID:6818599
Promoter ID:MM_KWN:1955
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:OTTMUST00000075107
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361129,396,776 - 129,397,276 (-)MPROMDB
RGD ID:6818600
Promoter ID:MM_KWN:1956
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000075106
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361129,433,906 - 129,434,406 (-)MPROMDB
RGD ID:6818602
Promoter ID:MM_KWN:1957
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung
Transcripts:OTTMUST00000075105,   OTTMUST00000078911
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361129,574,219 - 129,574,719 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1919410 AgrOrtholog
Ensembl Genes ENSMUSG00000026347 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000027585.14 UniProtKB/Swiss-Prot
  ENSMUST00000160616.8 UniProtKB/Swiss-Prot
  ENSMUST00000185560 ENTREZGENE
  ENSMUST00000185560.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1510.10 UniProtKB/Swiss-Prot
InterPro Cation_efflux_TMD_sf UniProtKB/Swiss-Prot
  Tmem163 UniProtKB/Swiss-Prot
KEGG Report mmu:72160 UniProtKB/Swiss-Prot
MGD MGI:1919410 ENTREZGENE
NCBI Gene 72160 ENTREZGENE
PANTHER PTHR31937 UniProtKB/Swiss-Prot
  TRANSMEMBRANE PROTEIN 163 UniProtKB/Swiss-Prot
PhenoGen Tmem163 PhenoGen
Superfamily-SCOP SSF161111 UniProtKB/Swiss-Prot
UniProt Q8C8I2 ENTREZGENE
  Q8C996 ENTREZGENE
  Q9D0E0 ENTREZGENE
  TM163_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8C8I2 UniProtKB/Swiss-Prot
  Q9D0E0 UniProtKB/Swiss-Prot