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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:733206 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EXOC6 mRNA | CTD | PMID:22079256 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of EXOC6 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | RGD:733206 | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of EXOC6 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of EXOC6 mRNA | CTD | PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of EXOC6 mRNA | CTD | PMID:21570461 | 2-hydroxypropanoic acid | decreases expression | ISO | RGD:733206 | 6480464 | Lactic Acid results in decreased expression of EXOC6 mRNA | CTD | PMID:30851411 | 6-propyl-2-thiouracil | decreases expression | ISO | RGD:3653 | 6480464 | Propylthiouracil results in decreased expression of EXOC6 mRNA | CTD | PMID:24780913 | aflatoxin B1 | decreases expression | ISO | RGD:733206 | 6480464 | Aflatoxin B1 results in decreased expression of EXOC6 mRNA | CTD | PMID:22100608 | aflatoxin B1 | decreases methylation | ISO | RGD:733206 | 6480464 | Aflatoxin B1 results in decreased methylation of EXOC6 gene | CTD | PMID:27153756 | ammonium chloride | affects expression | ISO | RGD:3653 | 6480464 | Ammonium Chloride affects the expression of EXOC6 mRNA | CTD | PMID:16483693 | aristolochic acid A | decreases expression | ISO | RGD:733206 | 6480464 | aristolochic acid I results in decreased expression of EXOC6 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | RGD:733206 | 6480464 | Arsenic affects the methylation of EXOC6 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:733206 | 6480464 | Arsenic affects the methylation of EXOC6 gene | CTD | PMID:25304211 | arsenite(3-) | increases expression | ISO | RGD:3653 | 6480464 | arsenite results in increased expression of EXOC6 protein | CTD | PMID:21344382 | atrazine | affects methylation | ISO | RGD:3653 | 6480464 | Atrazine affects the methylation of EXOC6 gene | CTD | PMID:28931070 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of EXOC6 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of EXOC6 exon, Benzo(a)pyrene results in decreased methylation of EXOC6 intron | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | RGD:733206 | 6480464 | Benzo(a)pyrene results in decreased expression of EXOC6 mRNA | CTD | PMID:20064835 more ... | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:733206 | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | affects expression | ISO | RGD:3653 | 6480464 | bisphenol A affects the expression of EXOC6 mRNA | CTD | PMID:25181051 | bisphenol A | increases methylation | ISO | RGD:733206 | 6480464 | bisphenol A results in increased methylation of EXOC6 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of EXOC6 mRNA | CTD | PMID:33221593 | bisphenol A | increases methylation | ISO | RGD:3653 | 6480464 | bisphenol A results in increased methylation of EXOC6 gene | CTD | PMID:28505145 | cadmium dichloride | increases methylation | ISO | RGD:3653 | 6480464 | Cadmium Chloride results in increased methylation of EXOC6 promoter | CTD | PMID:22457795 | cisplatin | decreases expression | ISO | RGD:733206 | 6480464 | Cisplatin results in decreased expression of EXOC6 mRNA | CTD | PMID:19561079 | cobalt dichloride | decreases expression | ISO | RGD:733206 | 6480464 | cobaltous chloride results in decreased expression of EXOC6 mRNA | CTD | PMID:19320972 | copper(II) sulfate | decreases expression | ISO | RGD:733206 | 6480464 | Copper Sulfate results in decreased expression of EXOC6 mRNA | CTD | PMID:19549813 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of EXOC6 mRNA | CTD | PMID:17361019, PMID:21266533 | dicrotophos | decreases expression | ISO | RGD:733206 | 6480464 | dicrotophos results in decreased expression of EXOC6 mRNA | CTD | PMID:28302478 | dorsomorphin | multiple interactions | ISO | RGD:733206 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EXOC6 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | RGD:733206 | 6480464 | Doxorubicin results in decreased expression of EXOC6 mRNA | CTD | PMID:29803840 | flutamide | increases expression | ISO | RGD:3653 | 6480464 | Flutamide results in increased expression of EXOC6 mRNA | CTD | PMID:24136188 | formaldehyde | decreases expression | ISO | RGD:733206 | 6480464 | Formaldehyde results in decreased expression of EXOC6 mRNA | CTD | PMID:23649840 | gentamycin | increases expression | ISO | RGD:3653 | 6480464 | Gentamicins results in increased expression of EXOC6 mRNA | CTD | PMID:33387578 | iron atom | affects metabolic processing | EXP | | 6480464 | EXOC6 protein affects the metabolism of Iron | CTD | PMID:17194590 | iron(0) | affects metabolic processing | EXP | | 6480464 | EXOC6 protein affects the metabolism of Iron | CTD | PMID:17194590 | lead(0) | affects expression | ISO | RGD:733206 | 6480464 | Lead affects the expression of EXOC6 mRNA | CTD | PMID:28903495 | lead(2+) | affects expression | ISO | RGD:733206 | 6480464 | Lead affects the expression of EXOC6 mRNA | CTD | PMID:28903495 | manganese atom | decreases expression | ISO | RGD:733206 | 6480464 | Manganese results in decreased expression of EXOC6 mRNA | CTD | PMID:17175027 | manganese(0) | decreases expression | ISO | RGD:733206 | 6480464 | Manganese results in decreased expression of EXOC6 mRNA | CTD | PMID:17175027 | manganese(II) chloride | decreases expression | ISO | RGD:733206 | 6480464 | manganese chloride results in decreased expression of EXOC6 mRNA | CTD | PMID:17175027 | melphalan | decreases expression | ISO | RGD:733206 | 6480464 | Melphalan results in decreased expression of EXOC6 mRNA | CTD | PMID:22363485 | methylmercury chloride | decreases expression | ISO | RGD:733206 | 6480464 | methylmercuric chloride results in decreased expression of EXOC6 mRNA | CTD | PMID:28001369 | nickel sulfate | decreases expression | ISO | RGD:733206 | 6480464 | nickel sulfate results in decreased expression of EXOC6 mRNA | CTD | PMID:16780908 | oxaliplatin | multiple interactions | ISO | RGD:3653 | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of EXOC6 mRNA | CTD | PMID:25729387 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of EXOC6 mRNA | CTD | PMID:17562736 | potassium chromate | decreases expression | ISO | RGD:733206 | 6480464 | potassium chromate(VI) results in decreased expression of EXOC6 mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | RGD:733206 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EXOC6 mRNA | CTD | PMID:22079256 | quercetin | decreases expression | ISO | RGD:733206 | 6480464 | Quercetin results in decreased expression of EXOC6 mRNA | CTD | PMID:21632981 | rac-lactic acid | decreases expression | ISO | RGD:733206 | 6480464 | Lactic Acid results in decreased expression of EXOC6 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | RGD:733206 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of EXOC6 mRNA | CTD | PMID:23557933 | S-nitroso-N-acetyl-D-penicillamine | decreases expression | ISO | RGD:3653 | 6480464 | S-Nitroso-N-Acetylpenicillamine results in decreased expression of SEC15 mRNA | CTD | PMID:12102619 | SB 431542 | multiple interactions | ISO | RGD:733206 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EXOC6 mRNA | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | RGD:733206 | 6480464 | Silicon Dioxide analog results in decreased expression of EXOC6 mRNA | CTD | PMID:25895662 | sodium arsenite | decreases expression | ISO | RGD:733206 | 6480464 | sodium arsenite results in decreased expression of EXOC6 protein | CTD | PMID:30528433 | temozolomide | increases expression | ISO | RGD:733206 | 6480464 | Temozolomide results in increased expression of EXOC6 mRNA | CTD | PMID:31758290 | testosterone | increases expression | ISO | RGD:733206 | 6480464 | Testosterone results in increased expression of EXOC6 mRNA | CTD | PMID:33359661 | thapsigargin | decreases expression | ISO | RGD:3653 | 6480464 | Thapsigargin results in decreased expression of EXOC6 protein | CTD | PMID:35544339 | thimerosal | increases expression | ISO | RGD:733206 | 6480464 | Thimerosal results in increased expression of EXOC6 mRNA | CTD | PMID:27188386 | topotecan | multiple interactions | ISO | RGD:3653 | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of EXOC6 mRNA | CTD | PMID:25729387 | topotecan | decreases expression | ISO | RGD:3653 | 6480464 | Topotecan results in decreased expression of EXOC6 mRNA | CTD | PMID:25729387 | trichostatin A | decreases expression | ISO | RGD:733206 | 6480464 | trichostatin A results in decreased expression of EXOC6 mRNA | CTD | PMID:24935251, PMID:26272509 | trichostatin A | multiple interactions | ISO | RGD:733206 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EXOC6 mRNA | CTD | PMID:27188386 | vancomycin | decreases expression | EXP | | 6480464 | Vancomycin results in decreased expression of EXOC6 mRNA | CTD | PMID:18930951 | vinclozolin | increases methylation | ISO | RGD:3653 | 6480464 | vinclozolin results in increased methylation of EXOC6 gene | CTD | PMID:31682807 | |