Errfi1 (ERBB receptor feedback inhibitor 1) - Rat Genome Database

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Gene: Errfi1 (ERBB receptor feedback inhibitor 1) Mus musculus
Analyze
Symbol: Errfi1
Name: ERBB receptor feedback inhibitor 1
RGD ID: 1332254
MGI Page MGI
Description: Predicted to enable SH3 domain binding activity; protein kinase binding activity; and small GTPase binding activity. Involved in several processes, including lung development; negative regulation of epidermal growth factor receptor signaling pathway; and skin morphogenesis. Acts upstream of or within several processes, including bile acid biosynthetic process; cholesterol homeostasis; and response to steroid hormone. Located in cytoplasm and plasma membrane. Is expressed in alveolar system; lung; and lung epithelium. Used to study endometrial cancer and osteoarthritis. Orthologous to human ERRFI1 (ERBB receptor feedback inhibitor 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1300002F13Rik; AI788755; Mig-; Mig-6; Mig6; mitogen-inducible gene 6 protein homolog; R; RALT
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394150,938,253 - 150,953,346 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4150,938,376 - 150,953,349 (+)EnsemblGRCm39 Ensembl
GRCm384150,853,796 - 150,868,889 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4150,853,919 - 150,868,892 (+)EnsemblGRCm38mm10GRCm38
MGSCv374150,229,200 - 150,242,989 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364149,698,891 - 149,712,680 (+)NCBIMGSCv36mm8
Celera4153,132,313 - 153,145,977 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map481.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (EXP)
(S)-nicotine  (EXP)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (EXP)
2-deoxy-D-glucose  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3',5'-cyclic AMP  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
astemizole  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bleomycin A2  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chloropicrin  (ISO)
chloroprene  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (EXP)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
dioxygen  (EXP,ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
fenthion  (EXP)
finasteride  (ISO)
fluoranthene  (EXP)
formaldehyde  (ISO)
furan  (ISO)
glyphosate  (EXP)
hydrogen cyanide  (EXP)
hydroxyurea  (ISO)
Indeno[1,2,3-cd]pyrene  (EXP)
inulin  (EXP)
iron dichloride  (ISO)
isoprenaline  (EXP)
kenpaullone  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
maneb  (EXP)
manganese(II) chloride  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methidathion  (EXP)
methylisothiazolinone  (ISO)
mocetinostat  (ISO)
naphthalene  (EXP)
naproxen  (ISO)
nefazodone  (ISO)
nickel dichloride  (ISO)
nicotine  (EXP)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium cyanide  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (EXP,ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
ritodrine  (EXP)
SB 203580  (EXP)
SB 431542  (ISO)
SCH 23390  (ISO)
sodium arsenite  (ISO)
sodium chromate  (ISO)
sulforaphane  (EXP)
sulindac  (ISO)
sumatriptan  (ISO)
tacedinaline  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
Theaflavin 3,3'-digallate  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
triptonide  (EXP)
troglitazone  (EXP,ISO)
trovafloxacin  (EXP)
tunicamycin  (EXP)
tyrphostin AG 1478  (ISO)
urethane  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vanadyl sulfate  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process  (IDA,IGI,IMP)
bile acid biosynthetic process  (IMP)
cartilage development  (IMP)
cell migration  (IDA,IMP)
cellular hyperosmotic response  (ISO)
cellular response to dexamethasone stimulus  (ISO)
cellular response to epidermal growth factor stimulus  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to platelet-derived growth factor stimulus  (ISO)
cholesterol homeostasis  (IMP)
cholesterol metabolic process  (IMP)
chondrocyte proliferation  (IMP)
embryo implantation  (IMP)
epidermal growth factor receptor signaling pathway  (IDA,IMP)
epithelial cell proliferation  (IMP)
epithelium development  (IMP)
fat pad development  (IMP)
gene expression  (IGI,IMP)
glucose metabolic process  (IMP)
limb joint morphogenesis  (IMP)
lipid metabolic process  (IMP)
liver development  (IMP)
lung alveolus development  (IMP)
lung epithelium development  (IMP)
lung vasculature development  (IMP)
negative regulation of cardiac muscle hypertrophy in response to stress  (ISO)
negative regulation of collagen biosynthetic process  (ISO)
negative regulation of epidermal growth factor receptor signaling pathway  (IBA,IMP,ISO)
negative regulation of ERK1 and ERK2 cascade  (ISO)
negative regulation of interleukin-1 beta production  (ISO)
negative regulation of peptidyl-tyrosine phosphorylation  (ISO)
negative regulation of protein autophosphorylation  (ISO)
negative regulation of tumor necrosis factor production  (ISO)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IMP)
progesterone receptor signaling pathway  (IMP)
protein localization to plasma membrane  (IMP)
regulation of keratinocyte differentiation  (IBA,IMP)
regulation of type B pancreatic cell proliferation  (ISO)
response to 1-oleoyl-sn-glycerol 3-phosphate  (IDA)
response to estradiol  (IDA)
response to insulin  (IMP)
response to progesterone  (IDA,IMP)
response to steroid hormone  (IMP)
response to xenobiotic stimulus  (IDA)
skeletal system development  (IMP)
skin development  (IMP)
skin morphogenesis  (IMP)
stress-activated protein kinase signaling cascade  (ISO)
tissue homeostasis  (IMP)
uterine epithelium development  (IMP)
uterus development  (IMP)

Cellular Component
cytoplasm  (IDA)
cytosol  (ISO)
membrane  (IEA)
nucleus  (IEA)
plasma membrane  (IDA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal articular cartilage morphology  (IAGP)
abnormal bone structure  (IAGP)
abnormal cartilage morphology  (IAGP)
abnormal eating behavior  (IAGP)
abnormal endochondral bone ossification  (IAGP)
abnormal endometrium morphology  (IAGP)
abnormal femur morphology  (IAGP)
abnormal foot pad morphology  (IAGP)
abnormal gait  (IAGP)
abnormal joint morphology  (IAGP)
abnormal lung development  (IAGP)
abnormal lung interstitium morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal lung vasculature morphology  (IAGP)
abnormal respiratory epithelium morphology  (IAGP)
abnormal skin morphology  (IAGP)
abnormal uterus morphology  (IAGP)
absent gastric milk in neonates  (IAGP)
accelerated temporomandibular joint osteoarthritis  (IAGP)
bronchial epithelial hyperplasia  (IAGP)
bronchiolar epithelial hyperplasia  (IAGP)
cyanosis  (IAGP)
decreased birth weight  (IAGP)
decreased locomotor activity  (IAGP)
delayed eyelid opening  (IAGP)
endometrium hyperplasia  (IAGP)
enlarged thymus  (IAGP)
epidermal hyperplasia  (IAGP)
female infertility  (IAGP)
flaky skin  (IAGP)
impaired lung alveolus development  (IAGP)
increased adenoma incidence  (IAGP)
increased carcinoma incidence  (IAGP)
increased chondrocyte number  (IAGP)
increased endometrial carcinoma incidence  (IAGP)
increased endometrial gland number  (IAGP)
increased incidence of tumors by chemical induction  (IAGP)
increased metastatic potential  (IAGP)
increased skin papilloma incidence  (IAGP)
increased type II pneumocyte number  (IAGP)
increased uterus weight  (IAGP)
joint swelling  (IAGP)
lung epithelium hyperplasia  (IAGP)
no abnormal phenotype detected  (IAGP)
osteoarthritis  (IAGP)
overexpanded pulmonary alveolus  (IAGP)
pale lung  (IAGP)
pathological neovascularization  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
rectal prolapse  (IAGP)
small lung  (IAGP)
spontaneous skin ulceration  (IAGP)
thick pulmonary interalveolar septum  (IAGP)
thick skin  (IAGP)
uterus hyperplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Targeted expression of receptor-associated late transducer inhibits maladaptive hypertrophy via blocking epidermal growth factor receptor signaling. Cai J, etal., Hypertension. 2009 Mar;53(3):539-48. doi: 10.1161/HYPERTENSIONAHA.108.120816. Epub 2009 Feb 9.
2. Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent stress. Makkinje A, etal., J Biol Chem. 2000 Jun 9;275(23):17838-47.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11003669   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15102471  
PMID:15489334   PMID:15747579   PMID:15782199   PMID:16007071   PMID:16087873   PMID:16141072   PMID:16141073   PMID:16247031   PMID:16648858   PMID:16705022   PMID:16819504   PMID:17987665  
PMID:18799693   PMID:19439667   PMID:19683494   PMID:19710174   PMID:20018910   PMID:20044804   PMID:20351267   PMID:20418913   PMID:21113414   PMID:21267068   PMID:21873635   PMID:22136853  
PMID:22912762   PMID:22975324   PMID:23175628   PMID:23204325   PMID:23375831   PMID:23384834   PMID:23811943   PMID:24550287   PMID:24966136   PMID:24989997   PMID:25377472   PMID:25486251  
PMID:25574067   PMID:25594850   PMID:25735773   PMID:25753424   PMID:25976672   PMID:26410627   PMID:26413869   PMID:27910070   PMID:28053990   PMID:28335007   PMID:28925396   PMID:29191600  
PMID:29336487   PMID:29843645   PMID:30773264   PMID:31089135   PMID:33172478   PMID:34358969   PMID:35232969  


Genomics

Comparative Map Data
Errfi1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394150,938,253 - 150,953,346 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4150,938,376 - 150,953,349 (+)EnsemblGRCm39 Ensembl
GRCm384150,853,796 - 150,868,889 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4150,853,919 - 150,868,892 (+)EnsemblGRCm38mm10GRCm38
MGSCv374150,229,200 - 150,242,989 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364149,698,891 - 149,712,680 (+)NCBIMGSCv36mm8
Celera4153,132,313 - 153,145,977 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map481.5NCBI
ERRFI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3818,011,727 - 8,026,309 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl18,004,404 - 8,026,309 (-)EnsemblGRCh38hg38GRCh38
GRCh3718,071,787 - 8,086,369 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3617,994,381 - 8,008,943 (-)NCBINCBI36Build 36hg18NCBI36
Celera17,178,838 - 7,193,452 (-)NCBICelera
Cytogenetic Map1p36.23NCBI
HuRef17,219,226 - 7,233,836 (-)NCBIHuRef
CHM1_118,059,534 - 8,074,168 (-)NCBICHM1_1
T2T-CHM13v2.017,542,658 - 7,557,236 (-)NCBIT2T-CHM13v2.0
Errfi1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85166,606,841 - 166,620,124 (+)NCBIGRCr8
mRatBN7.25161,323,981 - 161,337,289 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5161,323,998 - 161,337,282 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5164,041,130 - 164,054,414 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05165,857,948 - 165,871,237 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05165,819,770 - 165,833,053 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05167,951,564 - 167,966,011 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5167,952,728 - 167,966,009 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05171,529,354 - 171,542,775 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45168,012,683 - 168,025,963 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15168,022,870 - 168,036,149 (+)NCBI
Celera5159,577,700 - 159,590,979 (+)NCBICelera
Cytogenetic Map5q36NCBI
Errfi1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554864,941,143 - 4,955,693 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554864,941,143 - 4,955,693 (+)NCBIChiLan1.0ChiLan1.0
ERRFI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21220,202,917 - 220,217,518 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11218,844,232 - 218,858,832 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016,771,619 - 6,786,217 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.118,019,048 - 8,033,674 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl18,011,848 - 8,033,674 (-)Ensemblpanpan1.1panPan2
ERRFI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1561,621,964 - 61,636,152 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl561,622,550 - 61,636,148 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha561,630,761 - 61,645,081 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0561,838,401 - 61,852,732 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl561,838,401 - 61,852,748 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1561,837,612 - 61,851,932 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0561,702,129 - 61,716,447 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0562,105,524 - 62,119,850 (-)NCBIUU_Cfam_GSD_1.0
Errfi1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505831,972,493 - 31,977,775 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366232,456,294 - 2,462,467 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366232,457,709 - 2,462,956 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERRFI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl668,669,153 - 68,682,623 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1668,667,651 - 68,682,629 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2663,118,704 - 63,121,787 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ERRFI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120123,738,971 - 123,753,575 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20123,738,973 - 123,755,809 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605427,772,809 - 27,787,441 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Errfi1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248183,868,814 - 3,882,960 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248183,868,089 - 3,882,960 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Errfi1
27 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:823
Count of miRNA genes:362
Interacting mature miRNAs:394
Transcripts:ENSMUST00000030811, ENSMUST00000073600, ENSMUST00000128640
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134654451156860686Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134654451156860686Mouse
1300553Athsq1_matherosclerosis susceptibility QTL 1 (mouse)Not determined4137617848151654550Mouse
1300780Cocrb16_mcocaine related behavior 16 (mouse)Not determined4138943725156860686Mouse

Markers in Region
AI788755  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384150,867,538 - 150,867,627UniSTSGRCm38
MGSCv374150,241,647 - 150,241,736UniSTSGRCm37
Celera4153,144,635 - 153,144,724UniSTS
Cytogenetic Map4E1UniSTS
Whitehead/MRC_RH41953.58UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001356323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_133753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK004851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL607084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB870611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP754554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU207371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000030811   ⟹   ENSMUSP00000030811
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4150,939,530 - 150,953,344 (+)Ensembl
GRCm38.p6 Ensembl4150,855,073 - 150,868,887 (+)Ensembl
RefSeq Acc Id: ENSMUST00000073600   ⟹   ENSMUSP00000073285
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4150,938,376 - 150,953,349 (+)Ensembl
GRCm38.p6 Ensembl4150,853,919 - 150,868,892 (+)Ensembl
RefSeq Acc Id: ENSMUST00000128640
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4150,939,530 - 150,940,271 (+)Ensembl
GRCm38.p6 Ensembl4150,855,073 - 150,855,814 (+)Ensembl
RefSeq Acc Id: NM_001356323   ⟹   NP_001343252
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394150,938,253 - 150,953,346 (+)NCBI
GRCm384150,853,796 - 150,868,889 (+)NCBI
Sequence:
RefSeq Acc Id: NM_133753   ⟹   NP_598514
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394150,939,527 - 150,953,346 (+)NCBI
GRCm384150,855,070 - 150,868,889 (+)NCBI
MGSCv374150,229,200 - 150,242,989 (+)RGD
Celera4153,132,313 - 153,145,977 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_598514   ⟸   NM_133753
- UniProtKB: Q99JZ7 (UniProtKB/Swiss-Prot),   Q3TK48 (UniProtKB/TrEMBL),   Q3TJN8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001343252   ⟸   NM_001356323
- UniProtKB: Q99JZ7 (UniProtKB/Swiss-Prot),   Q3TK48 (UniProtKB/TrEMBL),   Q3TJN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000073285   ⟸   ENSMUST00000073600
RefSeq Acc Id: ENSMUSP00000030811   ⟸   ENSMUST00000030811
Protein Domains
Cdc42 binding   Mig-6

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99JZ7-F1-model_v2 AlphaFold Q99JZ7 1-461 view protein structure

Promoters
RGD ID:6835279
Promoter ID:MM_KWN:40951
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:ENSMUST00000073600
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364150,227,821 - 150,228,321 (+)MPROMDB
RGD ID:6835306
Promoter ID:MM_KWN:40952
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000030811,   ENSMUST00000105678,   OTTMUST00000023608
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364150,228,366 - 150,229,852 (+)MPROMDB
RGD ID:6847802
Promoter ID:MM_ACW:36697
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day3,   3T3L1_Day4,   Lung
Transcripts:ERRFI1.CSEP07,   ERRFI1.ESEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364150,239,266 - 150,240,137 (+)MPROMDB
RGD ID:6885618
Promoter ID:EPDNEW_M6260
Type:multiple initiation site
Name:Errfi1_1
Description:Mus musculus ERBB receptor feedback inhibitor 1 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384150,855,073 - 150,855,133EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921405 AgrOrtholog
Ensembl Genes ENSMUSG00000028967 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000030811 ENTREZGENE
  ENSMUST00000030811.2 UniProtKB/Swiss-Prot
  ENSMUST00000073600 ENTREZGENE
  ENSMUST00000073600.9 UniProtKB/Swiss-Prot
InterPro Cdc42_binding_dom-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mig-6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:74155 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1921405 ENTREZGENE
NCBI Gene 74155 ENTREZGENE
PANTHER ERBB RECEPTOR FEEDBACK INHIBITOR 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GENE 33 POLYPEPTIDE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GTPase_binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Inhibitor_Mig-6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Errfi1 PhenoGen
UniProt ERRFI_MOUSE UniProtKB/Swiss-Prot
  Q3TJN8 ENTREZGENE, UniProtKB/TrEMBL
  Q3TK48 ENTREZGENE, UniProtKB/TrEMBL
  Q99JZ7 ENTREZGENE