Socs2 (suppressor of cytokine signaling 2) - Rat Genome Database

Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Community Projects Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Socs2 (suppressor of cytokine signaling 2) Mus musculus
Analyze
Symbol: Socs2
Name: suppressor of cytokine signaling 2
RGD ID: 1332166
MGI Page MGI
Description: Enables growth hormone receptor binding activity. Acts upstream of or within several processes, including mammary gland development; negative regulation of receptor signaling pathway via JAK-STAT; and positive regulation of neuron differentiation. Predicted to be part of phosphatidylinositol 3-kinase complex. Is expressed in several structures, including lung; retina; spleen; testis; and ureteric tip. Human ortholog(s) of this gene implicated in endometrial cancer and ovarian carcinoma. Orthologous to human SOCS2 (suppressor of cytokine signaling 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 8030460M17; AI527257; AW108012; CI; Cis; CIS-2; CIS2; Cish2; cytokine inducible SH2-containing protein 2; cytokine-inducible SH2 protein 2; D130043N08Rik; hg; JA; JAB; MGC118106; SOC; SOCS-2; SS; SSI-2; STAT-induced STAT inhibitor 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm9847  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391095,219,765 - 95,253,176 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1095,221,224 - 95,253,042 (-)EnsemblGRCm39 Ensembl
GRCm381095,383,903 - 95,417,321 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1095,385,362 - 95,417,180 (-)EnsemblGRCm38mm10GRCm38
MGSCv371094,874,124 - 94,879,491 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361094,841,730 - 94,846,509 (-)NCBIMGSCv36mm8
Celera1097,386,894 - 97,392,261 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1049.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3-methylcholanthrene  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
9-cis-retinoic acid  (ISO)
acetylsalicylic acid  (EXP)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antigen  (EXP)
antimycin A  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzoates  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chlordecone  (EXP)
choline  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
clorgyline  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyanocob(III)alamin  (EXP)
cycloheximide  (EXP)
cyclosporin A  (ISO)
cypermethrin  (EXP)
D-glucose  (EXP)
deguelin  (ISO)
deoxynivalenol  (EXP)
dexamethasone  (EXP)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
disodium selenite  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
entinostat  (ISO)
enzalutamide  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
fenpyroximate  (ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
formaldehyde  (ISO)
fructose  (EXP)
gamma-hexachlorocyclohexane  (ISO)
genistein  (EXP)
glucose  (EXP)
glycine betaine  (EXP)
glyphosate  (ISO)
hexachlorobenzene  (ISO)
hexadecanoic acid  (ISO)
isotretinoin  (ISO)
L-methionine  (EXP)
leflunomide  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
lipoxin A4  (EXP)
maneb  (EXP)
mercury dibromide  (ISO)
metacetamol  (EXP)
methapyrilene  (ISO)
methimazole  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (ISO)
monosodium L-glutamate  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
niclosamide  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (EXP)
oleic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenformin  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
protein kinase inhibitor  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sotorasib  (ISO)
starch  (ISO)
sulfadimethoxine  (ISO)
sulfasalazine  (EXP)
sunitinib  (ISO)
tamoxifen  (EXP)
tebufenpyrad  (ISO)
temozolomide  (ISO)
testosterone  (EXP,ISO)
thioacetamide  (ISO)
trametinib  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
trovafloxacin  (EXP,ISO)
tunicamycin  (EXP,ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
zinc atom  (EXP,ISO)
zinc sulfate  (ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal body weight  (IAGP)
abnormal bone trabecula morphology  (IAGP)
abnormal circulating cytokine level  (IAGP)
abnormal circulating hormone level  (IAGP)
abnormal energy expenditure  (IAGP)
abnormal fertility/fecundity  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal hepatobiliary system morphology  (IAGP)
abnormal insulin-like growth factor I level  (IAGP)
abnormal long bone epiphyseal plate proliferative zone  (IAGP)
abnormal lung morphology  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal pancreatic duct morphology  (IAGP)
abnormal salivary gland duct morphology  (IAGP)
abnormal tibia morphology  (IAGP)
abnormal urine homeostasis  (IAGP)
decreased bone trabecular spacing  (IAGP)
decreased circulating growth hormone level  (IAGP)
decreased circulating insulin-like growth factor I level  (IAGP)
decreased energy expenditure  (IAGP)
decreased grip strength  (IEA)
decreased liver triglyceride level  (IAGP)
decreased susceptibility to diet-induced hepatic steatosis  (IAGP)
impaired glucose tolerance  (IAGP)
increased body length  (IAGP)
increased body weight  (IAGP)
increased bone trabecula number  (IAGP)
increased circulating creatinine level  (IEA)
increased circulating glucose level  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating interferon-gamma level  (IAGP)
increased circulating interleukin-1 beta level  (IAGP)
increased compact bone area  (IAGP)
increased diameter of tibia  (IAGP)
increased growth rate  (IAGP)
increased interferon-gamma secretion  (IAGP)
increased interleukin-1 beta secretion  (IAGP)
increased length of long bones  (IAGP)
increased long bone epiphyseal plate size  (IAGP)
increased renal fat pad weight  (IAGP)
increased skeletal muscle triglyceride level  (IAGP)
increased spleen weight  (IEA)
increased trabecular bone thickness  (IAGP)
increased trabecular bone volume  (IAGP)
increased tumor necrosis factor secretion  (IAGP)
increased width of hypertrophic chondrocyte zone  (IAGP)
insulin resistance  (IAGP)
liver inflammation  (IAGP)
long femur  (IAGP)
long humerus  (IAGP)
long radius  (IAGP)
long tibia  (IAGP)
thick dermal layer  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Methylated DNA collected by tampons--a new tool to detect endometrial cancer. Fiegl H, etal., Cancer Epidemiol Biomarkers Prev. 2004 May;13(5):882-8.
2. Favorable prognostic value of SOCS2 and IGF-I in breast cancer. Haffner MC, etal., BMC Cancer. 2007 Jul 25;7:136.
3. Evolution of the androgen receptor pathway during progression of prostate cancer. Hendriksen PJ, etal., Cancer Res. 2006 May 15;66(10):5012-20.
4. Twenty proteins containing a C-terminal SOCS box form five structural classes. Hilton DJ, etal., Proc Natl Acad Sci U S A 1998 Jan 6;95(1):114-9.
5. Sepsis-induced muscle growth hormone resistance occurs independently of STAT5 phosphorylation. Hong-Brown LQ, etal., Am J Physiol Endocrinol Metab. 2003 Jul;285(1):E63-72. Epub 2003 Mar 18.
6. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. MGD IEA MGD IEA
9. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. Suppressor of cytokine signalling gene expression is elevated in breast carcinoma. Raccurt M, etal., Br J Cancer. 2003 Aug 4;89(3):524-32.
13. Mouse MP Annotation Import Pipeline RGD automated import pipeline
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. GeneChip analysis after acute spinal cord injury in rat. Song G, etal., J Neurochem. 2001 Nov;79(4):804-15.
16. Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1. Starr R, etal., Proc Natl Acad Sci U S A 1998 Nov 24;95(24):14395-9.
17. Differential hypermethylation of SOCS genes in ovarian and breast carcinomas. Sutherland KD, etal., Oncogene. 2004 Oct 7;23(46):7726-33.
Additional References at PubMed
PMID:1936984   PMID:1938644   PMID:3957811   PMID:5168371   PMID:5664389   PMID:6530139   PMID:7789774   PMID:7868304   PMID:8661704   PMID:8769367   PMID:8853393   PMID:8884282  
PMID:9111530   PMID:9202125   PMID:9344848   PMID:9806843   PMID:9844915   PMID:9889194   PMID:10349636   PMID:10360382   PMID:10374907   PMID:10377060   PMID:10490099   PMID:10490100  
PMID:10490101   PMID:10641589   PMID:10867663   PMID:10890450   PMID:10969883   PMID:11015596   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11309659   PMID:11401434   PMID:11445538  
PMID:12040024   PMID:12208853   PMID:12368809   PMID:12396724   PMID:12459263   PMID:12477932   PMID:12682261   PMID:14610273   PMID:15090034   PMID:15100267   PMID:15240659   PMID:15300589  
PMID:15319356   PMID:15371557   PMID:15525267   PMID:15563548   PMID:15644415   PMID:15690087   PMID:15734145   PMID:15761851   PMID:15831713   PMID:15837129   PMID:15965258   PMID:16097082  
PMID:16141072   PMID:16141073   PMID:16360125   PMID:16406727   PMID:16410303   PMID:16419040   PMID:16469767   PMID:16574995   PMID:16602821   PMID:16670015   PMID:16675518   PMID:16684815  
PMID:17110492   PMID:17666591   PMID:18287559   PMID:18439298   PMID:18566962   PMID:18799693   PMID:18803233   PMID:19336533   PMID:19385048   PMID:19554387   PMID:19884258   PMID:19919527  
PMID:20032064   PMID:20348236   PMID:20499047   PMID:20854017   PMID:21099320   PMID:21646394   PMID:21677750   PMID:21844389   PMID:21873635   PMID:21980433   PMID:22228213   PMID:22547696  
PMID:22562833   PMID:22658486   PMID:22693634   PMID:22824785   PMID:23455506   PMID:23548639   PMID:23949579   PMID:24031028   PMID:24210661   PMID:24352701   PMID:24484474   PMID:24966052  
PMID:25057888   PMID:25074853   PMID:25833299   PMID:25858143   PMID:25894659   PMID:26410627   PMID:26562042   PMID:26703468   PMID:27131881   PMID:27330188   PMID:27477504   PMID:27646480  
PMID:27655030   PMID:28009300   PMID:28122728   PMID:28383049   PMID:28666115   PMID:28705898   PMID:29343614   PMID:29361558   PMID:29445148   PMID:29881947   PMID:30778220   PMID:31578312  
PMID:31816561   PMID:32255569   PMID:32541140   PMID:32733634   PMID:32800922   PMID:32994169   PMID:33002329   PMID:33933990   PMID:34954347   PMID:35033752   PMID:35352806   PMID:36398696  
PMID:36455458   PMID:36912916  


Genomics

Comparative Map Data
Socs2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391095,219,765 - 95,253,176 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1095,221,224 - 95,253,042 (-)EnsemblGRCm39 Ensembl
GRCm381095,383,903 - 95,417,321 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1095,385,362 - 95,417,180 (-)EnsemblGRCm38mm10GRCm38
MGSCv371094,874,124 - 94,879,491 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361094,841,730 - 94,846,509 (-)NCBIMGSCv36mm8
Celera1097,386,894 - 97,392,261 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1049.35NCBI
SOCS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381293,569,969 - 93,626,236 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1293,569,814 - 93,583,487 (+)EnsemblGRCh38hg38GRCh38
GRCh371293,963,745 - 93,970,521 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361292,487,729 - 92,494,109 (+)NCBINCBI36Build 36hg18NCBI36
Build 341292,466,065 - 92,472,446NCBI
Celera1293,634,235 - 93,640,615 (+)NCBICelera
Cytogenetic Map12q22NCBI
HuRef1291,011,433 - 91,037,277 (+)NCBIHuRef
CHM1_11293,928,550 - 93,935,473 (+)NCBICHM1_1
T2T-CHM13v2.01293,551,422 - 93,607,676 (+)NCBIT2T-CHM13v2.0
Socs2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2730,006,360 - 30,045,161 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl730,008,578 - 30,043,548 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx732,027,095 - 32,029,699 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0734,201,426 - 34,204,033 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0733,970,650 - 33,973,258 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0736,495,496 - 36,500,878 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl736,495,480 - 36,499,784 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0736,558,014 - 36,560,623 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4732,605,714 - 32,608,323 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1732,625,999 - 32,628,594 (-)NCBI
Celera727,114,252 - 27,116,861 (-)NCBICelera
Cytogenetic Map7q13NCBI
Socs2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540530,366,866 - 30,375,468 (+)EnsemblChiLan1.0
ChiLan1.0 EnsemblNW_00495540530,451,887 - 30,623,230 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540530,349,956 - 30,623,849 (+)NCBIChiLan1.0ChiLan1.0
SOCS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan112101,611,649 - 101,628,420 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01291,115,319 - 91,134,191 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11294,514,455 - 94,520,748 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1294,514,455 - 94,520,748 (+)Ensemblpanpan1.1panPan2
SOCS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11533,761,434 - 33,788,973 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1533,785,545 - 33,877,869 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1534,233,462 - 34,239,473 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01534,451,284 - 34,457,258 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1534,451,551 - 34,494,605 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11533,731,935 - 33,737,949 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01533,821,213 - 33,827,198 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01534,083,449 - 34,089,425 (+)NCBIUU_Cfam_GSD_1.0
Socs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494526,219,956 - 26,221,450 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650710,012,101 - 10,014,456 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493650710,013,982 - 10,015,480 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOCS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl589,581,090 - 89,584,581 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1589,581,081 - 89,587,424 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2593,712,446 - 93,718,768 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SOCS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11188,964,805 - 88,971,147 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1188,966,940 - 88,971,515 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037156,190,952 - 156,197,857 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Socs2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475013,333,393 - 13,339,018 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Socs2
1339 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3031
Count of miRNA genes:889
Interacting mature miRNAs:1206
Transcripts:ENSMUST00000020215, ENSMUST00000119917, ENSMUST00000128363, ENSMUST00000128854, ENSMUST00000129942, ENSMUST00000130784, ENSMUST00000134918, ENSMUST00000135822, ENSMUST00000139210, ENSMUST00000145847, ENSMUST00000150432, ENSMUST00000155148, ENSMUST00000170690, ENSMUST00000172070
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1044876096115935905Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
13208560Wght9_mweight 9 (mouse)1059835822120835905Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1063935779115935905Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106549093899491121Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106549093899491121Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106549093899491121Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067335830111735905Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073506901107507047Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075338568109338767Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75338568109338767Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075338568109338767Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078381268112381268Mouse
14747004Mancz8_mmandible centroid size 8 (mouse)1082078412116078412Mouse
11059554Lmr32e_mleishmaniasis resistance 32e (mouse)1082309418116309657Mouse
11059555Lmr32f_mleishmaniasis resistance 32f (mouse)1082309418116309657Mouse
11059550Lmr32a_mleishmaniasis resistance 32a (mouse)1082309418116309657Mouse
11059551Lmr32b_mleishmaniasis resistance 32b (mouse)1082309418116309657Mouse
11059553Lmr32d_mleishmaniasis resistance 32d (mouse)1082309418116309657Mouse
1301165Lith7_mlithogenic gene 7 (mouse)Not determined1082309418116309657Mouse
10043881Adip24_madiposity 24 (mouse)Not determined1082392803116392952Mouse
4141054mwfh_mmodifier of white forlock hypopigmentation (mouse)Not determined83017003117017136Mouse
1357594Estoq3_membryo survival total QTL 3 (mouse)Not determined1084079650122041528Mouse
1357622Espq3_membryo survival preimplantation QTL 3 (mouse)Not determined1084079650122041528Mouse
4141479W10q8_mweight 10 weeks QTL 8 (mouse)Not determined84079650122041528Mouse
4142496W6q8_mweight 6 weeks QTL 8 (mouse)Not determined84079650122041528Mouse
4141387Lgaq5_mlate growth adjusted QTL 5 (mouse)Not determined84079650122041528Mouse
4142365Egq9_mearly growth QTL 9 (mouse)Not determined84079650122041528Mouse
1357779Tesq3_mtestis weight QTL 3 (mouse)Not determined1084079650122041528Mouse
1357638Cia29_mcollagen induced arthritis 29 (mouse)Not determined1085454982118497353Mouse
1300797Sluc22_msusceptibility to lung cancer 22 (mouse)Not determined1086713608120713756Mouse
1300908Insq4_minsulin QTL 4 (mouse)Not determined1086909085120909229Mouse
1301520Uvbi1_mUVB induced immunosuppression 1 (mouse)Not determined1086909085120909229Mouse
1357831Igf1sl2_mIGF-1 serum levels 2 (mouse)Not determined108769412799936278Mouse
1300921Skl4_mskeletal size (tail length) 4 (mouse)Not determined1088088254122088391Mouse
4142386Tgq20_mtriglyceride QTL 20 (mouse)Not determined88836456122836456Mouse
1301758Fcsa3_mfemoral cross-sectional area 3 (mouse)Not determined1089927651123927754Mouse
11039516Ltpr5_mLeishmania tropica response 5 (mouse)1090506901125575232Mouse
13208554Lgth11_mbody length 11 (mouse)1090835862120835905Mouse
1302162Ednrbm1_mendothelin receptor type B modifier 1 (mouse)Not determined1092127383103713756Mouse
12910821Ogrq4_moverall growth rate QTL 4 (mouse)1092169056107319989Mouse
4142074Tmevp2_mTheiler's murine encephalomyelitis virus persistence 2 (mouse)Not determined92729941111568319Mouse

Markers in Region
AW108012  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381095,412,332 - 95,412,431UniSTSGRCm38
MGSCv371094,874,966 - 94,875,065UniSTSGRCm37
Celera1576,491,892 - 76,491,962UniSTS
Celera1097,387,736 - 97,387,835UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map10C2UniSTS
cM Map1052.0UniSTS
AI527257  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381574,985,624 - 74,985,850UniSTSGRCm38
GRCm381095,411,732 - 95,411,964UniSTSGRCm38
MGSCv371094,874,366 - 94,874,598UniSTSGRCm37
MGSCv371574,816,054 - 74,816,280UniSTSGRCm37
Celera1576,491,210 - 76,491,436UniSTS
Celera1097,387,136 - 97,387,368UniSTS
Cytogenetic Map10C2UniSTS
cM Map1052.0UniSTS
Whitehead/MRC_RH101071.84UniSTS
UniSTS:236444  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381574,986,340 - 74,986,649UniSTSGRCm38
GRCm381095,412,399 - 95,412,713UniSTSGRCm38
MGSCv371094,875,033 - 94,875,347UniSTSGRCm37
MGSCv371574,816,770 - 74,817,079UniSTSGRCm37
Celera1576,491,930 - 76,492,239UniSTS
Celera1097,387,803 - 97,388,117UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map15D3UniSTS
cM Map1052.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001168655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001168656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001168657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC167222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AE016773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF292933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC106153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY069559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000020215   ⟹   ENSMUSP00000020215
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,247,352 - 95,252,719 (-)Ensembl
GRCm38.p6 Ensembl1095,411,490 - 95,416,857 (-)Ensembl
RefSeq Acc Id: ENSMUST00000119917   ⟹   ENSMUSP00000113378
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,248,478 - 95,251,145 (-)Ensembl
GRCm38.p6 Ensembl1095,412,616 - 95,415,283 (-)Ensembl
RefSeq Acc Id: ENSMUST00000128363
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,249,364 - 95,252,530 (-)Ensembl
GRCm38.p6 Ensembl1095,413,502 - 95,416,668 (-)Ensembl
RefSeq Acc Id: ENSMUST00000128854
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,224,216 - 95,248,596 (-)Ensembl
GRCm38.p6 Ensembl1095,388,354 - 95,412,734 (-)Ensembl
RefSeq Acc Id: ENSMUST00000129942   ⟹   ENSMUSP00000117576
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,248,924 - 95,252,074 (-)Ensembl
GRCm38.p6 Ensembl1095,413,062 - 95,416,212 (-)Ensembl
RefSeq Acc Id: ENSMUST00000130784
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,223,529 - 95,228,829 (-)Ensembl
GRCm38.p6 Ensembl1095,387,667 - 95,392,967 (-)Ensembl
RefSeq Acc Id: ENSMUST00000134918
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,248,282 - 95,250,689 (-)Ensembl
GRCm38.p6 Ensembl1095,412,420 - 95,414,827 (-)Ensembl
RefSeq Acc Id: ENSMUST00000135822   ⟹   ENSMUSP00000118720
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,248,872 - 95,253,042 (-)Ensembl
GRCm38.p6 Ensembl1095,413,010 - 95,417,180 (-)Ensembl
RefSeq Acc Id: ENSMUST00000139210   ⟹   ENSMUSP00000121305
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,221,224 - 95,248,971 (-)Ensembl
GRCm38.p6 Ensembl1095,385,362 - 95,413,109 (-)Ensembl
RefSeq Acc Id: ENSMUST00000145847
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,250,953 - 95,251,861 (-)Ensembl
GRCm38.p6 Ensembl1095,415,091 - 95,415,999 (-)Ensembl
RefSeq Acc Id: ENSMUST00000150432   ⟹   ENSMUSP00000117785
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,248,900 - 95,251,346 (-)Ensembl
GRCm38.p6 Ensembl1095,413,038 - 95,415,484 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155148
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,237,198 - 95,248,856 (-)Ensembl
GRCm38.p6 Ensembl1095,401,336 - 95,412,994 (-)Ensembl
RefSeq Acc Id: ENSMUST00000170690   ⟹   ENSMUSP00000129331
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,247,352 - 95,252,074 (-)Ensembl
GRCm38.p6 Ensembl1095,411,490 - 95,416,212 (-)Ensembl
RefSeq Acc Id: ENSMUST00000172070   ⟹   ENSMUSP00000131875
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1095,247,352 - 95,251,346 (-)Ensembl
GRCm38.p6 Ensembl1095,411,490 - 95,415,484 (-)Ensembl
RefSeq Acc Id: NM_001168655   ⟹   NP_001162126
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,247,352 - 95,252,074 (-)NCBI
GRCm381095,411,490 - 95,416,212 (-)NCBI
MGSCv371094,874,124 - 94,879,491 (-)RGD
Celera1097,386,894 - 97,392,261 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001168656   ⟹   NP_001162127
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,247,352 - 95,251,346 (-)NCBI
GRCm381095,411,490 - 95,415,484 (-)NCBI
MGSCv371094,874,124 - 94,879,491 (-)RGD
Celera1097,386,894 - 97,392,261 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001168657   ⟹   NP_001162128
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,247,352 - 95,251,145 (-)NCBI
GRCm381095,411,490 - 95,415,283 (-)NCBI
MGSCv371094,874,124 - 94,879,491 (-)RGD
Celera1097,386,894 - 97,392,261 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_007706   ⟹   NP_031732
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,247,352 - 95,252,719 (-)NCBI
GRCm381095,411,490 - 95,416,857 (-)NCBI
MGSCv371094,874,124 - 94,879,491 (-)RGD
Celera1097,386,894 - 97,392,261 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006513515   ⟹   XP_006513578
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,227,674 - 95,252,721 (-)NCBI
GRCm381095,391,812 - 95,417,070 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006513517   ⟹   XP_006513580
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,244,211 - 95,252,721 (-)NCBI
GRCm381095,408,349 - 95,417,069 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243406   ⟹   XP_011241708
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,219,765 - 95,252,568 (-)NCBI
GRCm381095,383,903 - 95,416,706 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243410   ⟹   XP_011241712
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,219,767 - 95,252,589 (-)NCBI
GRCm381095,411,504 - 95,416,717 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017313896   ⟹   XP_017169385
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,219,765 - 95,252,712 (-)NCBI
GRCm381095,383,903 - 95,417,077 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017313897   ⟹   XP_017169386
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,219,765 - 95,252,568 (-)NCBI
GRCm381095,383,903 - 95,416,706 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017313898   ⟹   XP_017169387
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,219,765 - 95,252,568 (-)NCBI
GRCm381095,383,903 - 95,416,706 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017313899   ⟹   XP_017169388
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,219,765 - 95,253,091 (-)NCBI
GRCm381095,383,903 - 95,417,321 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017313900   ⟹   XP_017169389
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,219,765 - 95,251,477 (-)NCBI
GRCm381095,383,903 - 95,415,615 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017313901   ⟹   XP_017169390
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,227,674 - 95,252,721 (-)NCBI
GRCm381095,391,812 - 95,417,069 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017313902   ⟹   XP_017169391
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,226,426 - 95,252,721 (-)NCBI
GRCm381095,390,564 - 95,417,068 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245028   ⟹   XP_030100888
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,227,674 - 95,252,568 (-)NCBI
GRCm381095,391,812 - 95,416,706 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245030   ⟹   XP_030100890
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,219,767 - 95,253,176 (-)NCBI
GRCm381095,411,501 - 95,417,305 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036155750   ⟹   XP_036011643
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,226,527 - 95,252,721 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036155751   ⟹   XP_036011644
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,219,767 - 95,252,934 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036155752   ⟹   XP_036011645
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,219,767 - 95,252,568 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036155753   ⟹   XP_036011646
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391095,219,767 - 95,251,477 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001162126 (Get FASTA)   NCBI Sequence Viewer  
  NP_001162127 (Get FASTA)   NCBI Sequence Viewer  
  NP_001162128 (Get FASTA)   NCBI Sequence Viewer  
  NP_031732 (Get FASTA)   NCBI Sequence Viewer  
  XP_006513578 (Get FASTA)   NCBI Sequence Viewer  
  XP_006513580 (Get FASTA)   NCBI Sequence Viewer  
  XP_011241708 (Get FASTA)   NCBI Sequence Viewer  
  XP_011241712 (Get FASTA)   NCBI Sequence Viewer  
  XP_017169385 (Get FASTA)   NCBI Sequence Viewer  
  XP_017169386 (Get FASTA)   NCBI Sequence Viewer  
  XP_017169387 (Get FASTA)   NCBI Sequence Viewer  
  XP_017169388 (Get FASTA)   NCBI Sequence Viewer  
  XP_017169389 (Get FASTA)   NCBI Sequence Viewer  
  XP_017169390 (Get FASTA)   NCBI Sequence Viewer  
  XP_017169391 (Get FASTA)   NCBI Sequence Viewer  
  XP_030100888 (Get FASTA)   NCBI Sequence Viewer  
  XP_030100890 (Get FASTA)   NCBI Sequence Viewer  
  XP_036011643 (Get FASTA)   NCBI Sequence Viewer  
  XP_036011644 (Get FASTA)   NCBI Sequence Viewer  
  XP_036011645 (Get FASTA)   NCBI Sequence Viewer  
  XP_036011646 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB62402 (Get FASTA)   NCBI Sequence Viewer  
  AAI06154 (Get FASTA)   NCBI Sequence Viewer  
  AAL76097 (Get FASTA)   NCBI Sequence Viewer  
  AAN84618 (Get FASTA)   NCBI Sequence Viewer  
  BAC28196 (Get FASTA)   NCBI Sequence Viewer  
  BAE23343 (Get FASTA)   NCBI Sequence Viewer  
  BAE35854 (Get FASTA)   NCBI Sequence Viewer  
  BAE36978 (Get FASTA)   NCBI Sequence Viewer  
  EDL21598 (Get FASTA)   NCBI Sequence Viewer  
  EDL21600 (Get FASTA)   NCBI Sequence Viewer  
  EDL21601 (Get FASTA)   NCBI Sequence Viewer  
  EDL21602 (Get FASTA)   NCBI Sequence Viewer  
  EDL21603 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000020215
  ENSMUSP00000113378
  ENSMUSP00000117576.2
  ENSMUSP00000117785.2
  ENSMUSP00000118720.2
  ENSMUSP00000121305.2
  ENSMUSP00000129331
  ENSMUSP00000131875
GenBank Protein O35717 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_031732   ⟸   NM_007706
- UniProtKB: O35717 (UniProtKB/Swiss-Prot),   Q548Q7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001162126   ⟸   NM_001168655
- UniProtKB: O35717 (UniProtKB/Swiss-Prot),   Q548Q7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001162127   ⟸   NM_001168656
- UniProtKB: O35717 (UniProtKB/Swiss-Prot),   Q548Q7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001162128   ⟸   NM_001168657
- UniProtKB: O35717 (UniProtKB/Swiss-Prot),   Q548Q7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006513578   ⟸   XM_006513515
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006513580   ⟸   XM_006513517
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_011241708   ⟸   XM_011243406
- Peptide Label: isoform X2
- UniProtKB: F6RVG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241712   ⟸   XM_011243410
- Peptide Label: isoform X7
- UniProtKB: O35717 (UniProtKB/Swiss-Prot),   Q548Q7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017169388   ⟸   XM_017313899
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017169386   ⟸   XM_017313897
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017169385   ⟸   XM_017313896
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017169387   ⟸   XM_017313898
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017169389   ⟸   XM_017313900
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017169391   ⟸   XM_017313902
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017169390   ⟸   XM_017313901
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_030100888   ⟸   XM_030245028
- Peptide Label: isoform X2
- UniProtKB: F6RVG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030100890   ⟸   XM_030245030
- Peptide Label: isoform X7
- UniProtKB: O35717 (UniProtKB/Swiss-Prot),   Q548Q7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000117785   ⟸   ENSMUST00000150432
RefSeq Acc Id: ENSMUSP00000113378   ⟸   ENSMUST00000119917
RefSeq Acc Id: ENSMUSP00000121305   ⟸   ENSMUST00000139210
RefSeq Acc Id: ENSMUSP00000131875   ⟸   ENSMUST00000172070
RefSeq Acc Id: ENSMUSP00000020215   ⟸   ENSMUST00000020215
RefSeq Acc Id: ENSMUSP00000129331   ⟸   ENSMUST00000170690
RefSeq Acc Id: ENSMUSP00000118720   ⟸   ENSMUST00000135822
RefSeq Acc Id: ENSMUSP00000117576   ⟸   ENSMUST00000129942
RefSeq Acc Id: XP_036011644   ⟸   XM_036155751
- Peptide Label: isoform X7
- UniProtKB: O35717 (UniProtKB/Swiss-Prot),   Q548Q7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036011645   ⟸   XM_036155752
- Peptide Label: isoform X7
- UniProtKB: O35717 (UniProtKB/Swiss-Prot),   Q548Q7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036011646   ⟸   XM_036155753
- Peptide Label: isoform X7
- UniProtKB: O35717 (UniProtKB/Swiss-Prot),   Q548Q7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036011643   ⟸   XM_036155750
- Peptide Label: isoform X5
Protein Domains
SH2   SOCS box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35717-F1-model_v2 AlphaFold O35717 1-198 view protein structure

Promoters
RGD ID:6818817
Promoter ID:MM_KWN:5426
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   Brain,   ES_Cell,   Kidney,   Liver,   Lung
Transcripts:AK017586_5730420D15RIK,   NM_001168655,   NM_001168656,   NM_001168657,   NM_007706,   OTTMUST00000070528,   OTTMUST00000070530,   OTTMUST00000070533,   OTTMUST00000070536
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361094,877,036 - 94,879,977 (+)MPROMDB
RGD ID:8673112
Promoter ID:EPDNEW_M14587
Type:multiple initiation site
Name:Socs2_2
Description:Mus musculus suppressor of cytokine signaling 2 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14588  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381095,415,206 - 95,415,266EPDNEW
RGD ID:8673114
Promoter ID:EPDNEW_M14588
Type:initiation region
Name:Socs2_1
Description:Mus musculus suppressor of cytokine signaling 2 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14587  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381095,416,803 - 95,416,863EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1201787 AgrOrtholog
Ensembl Genes ENSMUSG00000020027 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020215 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000119917 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000129942.2 UniProtKB/TrEMBL
  ENSMUST00000135822.8 UniProtKB/TrEMBL
  ENSMUST00000139210.8 UniProtKB/TrEMBL
  ENSMUST00000150432.8 UniProtKB/TrEMBL
  ENSMUST00000170690 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000172070 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.505.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS2_SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS_box-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:216233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1201787 ENTREZGENE
NCBI Gene 216233 ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10155:SF7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Socs2 PhenoGen
PRINTS SH2DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOCS_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF158235 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3YZ26_MOUSE UniProtKB/TrEMBL
  D3Z355_MOUSE UniProtKB/TrEMBL
  D3Z441_MOUSE UniProtKB/TrEMBL
  F6RVG2 ENTREZGENE, UniProtKB/TrEMBL
  O35717 ENTREZGENE
  Q548Q7 ENTREZGENE, UniProtKB/TrEMBL
  Q8CCG3_MOUSE UniProtKB/TrEMBL
  SOCS2_MOUSE UniProtKB/Swiss-Prot