Mrgprg (MAS-related GPR, member G) - Rat Genome Database

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Gene: Mrgprg (MAS-related GPR, member G) Mus musculus
Analyze
Symbol: Mrgprg
Name: MAS-related GPR, member G
RGD ID: 1332153
MGI Page MGI
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human MRGPRG (MAS related GPR family member G).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: evolutionary breakpoint transcript 2 protein; G protein-coupled receptor MrgG; Gm1098; mas-related G-protein coupled receptor member G; Mrg; Mrgg
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397143,317,447 - 143,320,730 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7143,317,447 - 143,320,730 (-)EnsemblGRCm39 Ensembl
GRCm387143,763,710 - 143,766,993 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7143,763,710 - 143,766,993 (-)EnsemblGRCm38mm10GRCm38
MGSCv377150,949,615 - 150,952,898 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367143,573,100 - 143,576,383 (-)NCBIMGSCv36mm8
Celera7143,520,089 - 143,523,372 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family. Zylka MJ, etal., Proc Natl Acad Sci U S A 2003 Aug 19;100(17):10043-8. Epub 2003 Aug 8.
Additional References at PubMed
PMID:11551509   PMID:12397184   PMID:12477932   PMID:16602821   PMID:21873635   PMID:38355793  


Genomics

Comparative Map Data
Mrgprg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397143,317,447 - 143,320,730 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7143,317,447 - 143,320,730 (-)EnsemblGRCm39 Ensembl
GRCm387143,763,710 - 143,766,993 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7143,763,710 - 143,766,993 (-)EnsemblGRCm38mm10GRCm38
MGSCv377150,949,615 - 150,952,898 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367143,573,100 - 143,576,383 (-)NCBIMGSCv36mm8
Celera7143,520,089 - 143,523,372 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.31NCBI
MRGPRG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38113,217,944 - 3,218,813 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl113,217,944 - 3,218,813 (-)EnsemblGRCh38hg38GRCh38
GRCh37113,239,174 - 3,240,043 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36113,195,750 - 3,198,081 (-)NCBINCBI36Build 36hg18NCBI36
Celera113,274,767 - 3,275,638 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef113,029,004 - 3,029,873 (-)NCBIHuRef
CHM1_1113,238,850 - 3,239,719 (-)NCBICHM1_1
T2T-CHM13v2.0113,308,916 - 3,309,785 (-)NCBIT2T-CHM13v2.0
Mrgprg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81208,377,008 - 208,380,916 (-)NCBIGRCr8
mRatBN7.21198,947,648 - 198,951,556 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1198,947,229 - 198,951,517 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1207,328,592 - 207,329,461 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01214,410,565 - 214,411,434 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01207,084,737 - 207,085,606 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01216,952,942 - 216,955,673 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,953,130 - 216,953,999 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01223,809,194 - 223,809,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41204,153,951 - 204,154,820 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11204,307,403 - 204,308,273 (-)NCBI
Celera1196,512,203 - 196,513,072 (-)NCBICelera
Cytogenetic Map1q42NCBI
Mrgprg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542214,962,676 - 14,967,828 (-)NCBIChiLan1.0ChiLan1.0
MRGPRG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v295,618,069 - 5,619,833 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1114,829,371 - 4,831,135 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0113,231,969 - 3,233,733 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1113,253,104 - 3,253,973 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl113,253,104 - 3,253,973 (-)Ensemblpanpan1.1panPan2
MRGPRG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11847,134,505 - 47,138,223 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1847,134,505 - 47,138,223 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1845,742,771 - 45,746,490 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01847,815,077 - 47,818,793 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1847,815,077 - 47,818,793 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11847,258,253 - 47,261,966 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01846,842,141 - 46,845,858 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01847,588,707 - 47,592,424 (-)NCBIUU_Cfam_GSD_1.0
Mrgprg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049473,362,728 - 3,364,387 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049367941,303,746 - 1,307,523 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRGPRG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.122,296,515 - 2,315,412 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MRGPRG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.113,035,191 - 3,038,635 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl13,035,455 - 3,036,324 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038100,229,634 - 100,231,252 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrgprg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476715,971,077 - 15,973,007 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mrgprg
59 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:405
Count of miRNA genes:275
Interacting mature miRNAs:318
Transcripts:ENSMUST00000058092
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7110967235144967336Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111166122144995196Mouse
1301590Pbwg3_mpostnatal body weight growth 3 (mouse)Not determined7127311241144995196Mouse
1300566Sluc8_msusceptibility to lung cancer 8 (mouse)Not determined7127398151144995196Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7109707335143707335Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111166122144995196Mouse
14746988Manh63_mmandible shape 63 (mouse)7127735437144995196Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7109707335143707335Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7109707335143707335Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112552248144995196Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7116634089144995196Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7112922733144995196Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111166122144995196Mouse
1357711Adbg1_madult body growth 1 (mouse)Not determined7118693381144398314Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7110967235144967336Mouse
1301773Stheal7_msoft tissue heal 7 (mouse)Not determined7119132573144995196Mouse


Sequence


Ensembl Acc Id: ENSMUST00000058092   ⟹   ENSMUSP00000060411
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7143,317,447 - 143,320,730 (-)Ensembl
GRCm38.p6 Ensembl7143,763,710 - 143,766,993 (-)Ensembl
Ensembl Acc Id: ENSMUST00000208986   ⟹   ENSMUSP00000146374
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7143,318,643 - 143,319,313 (-)Ensembl
GRCm38.p6 Ensembl7143,764,906 - 143,765,576 (-)Ensembl
RefSeq Acc Id: NM_203492   ⟹   NP_987077
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,317,447 - 143,320,730 (-)NCBI
GRCm387143,763,710 - 143,766,993 (-)ENTREZGENE
MGSCv377150,949,615 - 150,952,898 (-)RGD
Celera7143,520,089 - 143,523,372 (-)RGD
cM Map7 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_987077 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI00303 (Get FASTA)   NCBI Sequence Viewer  
  AAK91803 (Get FASTA)   NCBI Sequence Viewer  
  CAC86130 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000060411
  ENSMUSP00000060411.7
  ENSMUSP00000146374.2
GenBank Protein Q91ZB5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_987077   ⟸   NM_203492
- UniProtKB: Q498A2 (UniProtKB/Swiss-Prot),   Q711N2 (UniProtKB/Swiss-Prot),   Q91ZB5 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000146374   ⟸   ENSMUST00000208986
Ensembl Acc Id: ENSMUSP00000060411   ⟸   ENSMUST00000058092

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q91ZB5-F1-model_v2 AlphaFold Q91ZB5 1-289 view protein structure

Promoters
RGD ID:8666267
Promoter ID:EPDNEW_M11165
Type:initiation region
Name:Mrgprg_1
Description:Mus musculus MAS-related GPR, member G , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387143,766,922 - 143,766,982EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3033145 AgrOrtholog
Ensembl Genes ENSMUSG00000050276 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000058092 ENTREZGENE
  ENSMUST00000058092.8 UniProtKB/Swiss-Prot
  ENSMUST00000208986.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRGPCRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRGPCRG UniProtKB/Swiss-Prot
KEGG Report mmu:381974 UniProtKB/Swiss-Prot
MGD MGI:3033145 ENTREZGENE
NCBI Gene 381974 ENTREZGENE
PANTHER PTHR11334 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11334:SF32 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mrgprg PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRGPCRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140LHD7_MOUSE UniProtKB/TrEMBL
  MRGRG_MOUSE UniProtKB/Swiss-Prot
  Q498A2 ENTREZGENE
  Q711N2 ENTREZGENE
  Q91ZB5 ENTREZGENE
UniProt Secondary Q498A2 UniProtKB/Swiss-Prot
  Q711N2 UniProtKB/Swiss-Prot