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Gene: Mast1 (microtubule associated serine/threonine kinase 1) Mus musculus
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Symbol: Mast1
Name: microtubule associated serine/threonine kinase 1
RGD ID: 1332131
Description: Exhibits microtubule binding activity. Involved in brain development and cytoskeleton organization. Localizes to membrane; neuron projection; and neuronal cell body. Is expressed in nervous system; neural retina; and skeletal muscle. Used to study mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations. Human ortholog(s) of this gene implicated in mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations. Orthologous to human MAST1 (microtubule associated serine/threonine kinase 1); INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9430008B02Rik; microtubule-associated serine/threonine-protein kinase 1; S; SAST; SAST170; syntrophin associated serine/threonine kinase; syntrophin-associated serine-threonine protein kinase; syntrophin-associated serine/threonine-protein kinase
Orthologs:
Homo sapiens (human) : MAST1 (microtubule associated serine/threonine kinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : MAST1 (microtubule associated serine/threonine kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mast1 (microtubule associated serine/threonine kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MAST1 (microtubule associated serine/threonine kinase 1)
Canis lupus familiaris (dog) : MAST1 (microtubule associated serine/threonine kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mast1 (microtubule associated serine/threonine kinase 1)
Sus scrofa (pig) : MAST1 (microtubule associated serine/threonine kinase 1)
Chlorocebus sabaeus (African green monkey) : MAST1 (microtubule associated serine/threonine kinase 1)
Heterocephalus glaber (naked mole-rat) : Mast1 (microtubule associated serine/threonine kinase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39885,638,482 - 85,672,811 (-)NCBI
GRCm38884,911,853 - 84,946,177 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl884,911,903 - 84,937,359 (-)EnsemblGRCm38mm10GRCm38
MGSCv37887,435,752 - 87,461,252 (-)NCBIGRCm37mm9NCBIm37
MGSCv36887,802,010 - 87,827,443 (-)NCBImm8
Celera889,211,248 - 89,236,672 (-)NCBICelera
Cytogenetic Map8C3NCBI
cM Map841.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mast1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1332131
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.