Cyrib (CYFIP related Rac1 interactor B) - Rat Genome Database

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Gene: Cyrib (CYFIP related Rac1 interactor B) Mus musculus
Analyze
Symbol: Cyrib
Name: CYFIP related Rac1 interactor B
RGD ID: 1332100
MGI Page MGI
Description: Enables MHC class Ib protein binding, via antigen binding activity groove. Involved in several processes, including positive regulation of T cell mediated cytotoxicity; positive regulation of memory T cell activation; and positive regulation of type II interferon production. Located in cilium. Orthologous to human CYRIB (CYFIP related Rac1 interactor B).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 0910001A06Rik; AW122079; CYFIP-related Rac1 interactor B; Fam49; Fam49b; family with sequence similarity 49, member B; hypothetical protein LOC223601
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391563,800,943 - 63,932,627 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1563,800,946 - 63,932,327 (-)EnsemblGRCm39 Ensembl
GRCm381563,929,094 - 64,060,778 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1563,929,097 - 64,060,478 (-)EnsemblGRCm38mm10GRCm38
MGSCv371563,760,649 - 63,892,010 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361563,758,763 - 63,890,121 (-)NCBIMGSCv36mm8
Celera1565,431,654 - 65,563,033 (-)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1528.16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cilium  (IDA)
membrane  (IEA)
mitochondrion  (ISO,ISS)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:17967808  
PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22326026   PMID:22522492   PMID:23055941   PMID:24859337   PMID:25737280   PMID:27626380   PMID:28378742   PMID:28671696  
PMID:29059164   PMID:31285585   PMID:32325033   PMID:35131594   PMID:37142655   PMID:38355793   PMID:38391912   PMID:38712822   PMID:39158947  


Genomics

Comparative Map Data
Cyrib
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391563,800,943 - 63,932,627 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1563,800,946 - 63,932,327 (-)EnsemblGRCm39 Ensembl
GRCm381563,929,094 - 64,060,778 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1563,929,097 - 64,060,478 (-)EnsemblGRCm38mm10GRCm38
MGSCv371563,760,649 - 63,892,010 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361563,758,763 - 63,890,121 (-)NCBIMGSCv36mm8
Celera1565,431,654 - 65,563,033 (-)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1528.16NCBI
CYRIB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388129,839,593 - 130,017,129 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8129,839,593 - 130,017,504 (-)EnsemblGRCh38hg38GRCh38
GRCh378130,851,839 - 131,029,375 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368130,922,898 - 131,021,182 (-)NCBINCBI36Build 36hg18NCBI36
Build 348130,922,899 - 131,021,182NCBI
Celera8127,031,822 - 127,130,443 (-)NCBICelera
Cytogenetic Map8q24.21NCBI
HuRef8126,170,455 - 126,302,342 (-)NCBIHuRef
CHM1_18130,892,084 - 131,069,252 (-)NCBICHM1_1
T2T-CHM13v2.08130,965,555 - 131,143,607 (-)NCBIT2T-CHM13v2.0
Cyrib
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8797,524,941 - 97,649,846 (-)NCBIGRCr8
mRatBN7.2795,633,876 - 95,760,588 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl795,633,876 - 95,697,686 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx797,406,820 - 97,531,642 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0799,608,486 - 99,733,302 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0799,530,454 - 99,655,160 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07104,514,566 - 104,641,875 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7104,516,391 - 104,556,419 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0791,517,911 - 91,644,771 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47101,150,480 - 101,275,452 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17101,184,709 - 101,246,506 (-)NCBI
Celera792,233,570 - 92,357,399 (-)NCBICelera
Cytogenetic Map7q33NCBI
Cyrib
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554614,632,263 - 4,662,016 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554614,634,324 - 4,786,723 (-)NCBIChiLan1.0ChiLan1.0
CYRIB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27147,210,064 - 147,386,043 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18122,726,860 - 122,902,812 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08126,478,020 - 126,653,936 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18129,209,655 - 129,341,048 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8129,209,655 - 129,272,844 (-)Ensemblpanpan1.1panPan2
CYRIB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11326,942,036 - 27,056,547 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1326,942,229 - 27,003,644 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1326,909,797 - 27,057,242 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01327,286,332 - 27,433,998 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1327,286,332 - 27,432,203 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11327,002,963 - 27,150,335 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01327,123,335 - 27,270,680 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01327,423,241 - 27,570,947 (-)NCBIUU_Cfam_GSD_1.0
Cyrib
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530311,268,360 - 11,377,229 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647018,721,037 - 18,804,065 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647018,665,898 - 18,803,864 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYRIB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1410,476,137 - 10,643,395 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2410,736,165 - 10,859,545 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CYRIB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18124,308,911 - 124,406,261 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8124,307,049 - 124,345,548 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603915,634,158 - 15,808,284 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cyrib
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473525,820,175 - 25,894,193 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473525,752,675 - 25,894,193 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cyrib
2338 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:919
Count of miRNA genes:490
Interacting mature miRNAs:577
Transcripts:ENSMUST00000063838, ENSMUST00000164532
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301779Dpml_mdopamine loss (mouse)Not determined155100469476794493Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
27226773Tibl16_mtibia length 16, 10 week (mouse)15692948175871849Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
1357703Vtbt17_mvertebral trabecular bone trait 17 (mouse)Not determined154455331378553437Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
1558786Msq1_mMAV-1 susceptibility QTL 1 (mouse)Not determined156338964681086436Mouse
1301006Hfib1_mhepatic fibrogenesis 1 (mouse)Not determined154730633481306479Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
10755515Amzn3_manatomical modifier of Zfp423 3 (mouse)154638964680389845Mouse
26884412Bzwq10_mbi-zygomatic width QTL 10, 10 week (mouse)15612948171471849Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154846536282465496Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1357756Alaa4_malopecia areata 4 (mouse)Not determined154638964680389845Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927302279474762Mouse
27226800Scvln20_msacral vertebrae length 2, 16 week (mouse)152660008666371849Mouse
26884392Humsd8_mhumerus midshaft diameter 8, 16 week (mouse)152930014676084200Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884387Skwq8_mskull length QTL 8, 10 week (mouse)15612948168271849Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15612948175871849Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
4142459Lfnq3_mlung function QTL 3 (mouse)Not determined4017702272372580Mouse
1357661Eae2b_msusceptibility to experimental allergic encephalomyelitis 2b (mouse)Not determined155100469464944308Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1301568Tria2_mT-cell receptor induced activation 2 (mouse)Not determined154485914178859281Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
26884417Bzwq4_mbi-zygomatic width QTL 4, 5 week (mouse)15612948172471849Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
26884420Cvht6_mcranial vault height 6, 10 week (mouse)154556339669171849Mouse
1301324Cdif_mcolor difference (mouse)Not determined153597590669976019Mouse
1301580Hrq2_mheart rate quantitative locus 2 (mouse)Not determined153910039573100593Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15612948176384200Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
10401902Sicd2_mseizure-induced cell death 2 (mouse)Not determined15347438971197538Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
1300578Cd8ts3_mCD8 T cell subset 3 (mouse)Not determined153400469468004804Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
1301860Gct3_mgranulosa cell tumorigenesis 3 (mouse)Not determined154740959681409691Mouse
27226721Tibw8_mtibia width 8, proximal, 16 week (mouse)15692948175871849Mouse

Markers in Region
AW122079  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381563,929,243 - 63,929,380UniSTSGRCm38
MGSCv371563,760,798 - 63,760,935UniSTSGRCm37
Celera1565,431,803 - 65,431,940UniSTS
Cytogenetic Map15D1UniSTS
Whitehead/MRC_RH15557.35UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001360035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001360036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001360037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001360038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_144846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC140673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC156573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC174724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK029846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX527479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK633763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000063838   ⟹   ENSMUSP00000066359
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1563,800,946 - 63,932,297 (-)Ensembl
GRCm38.p6 Ensembl1563,929,097 - 64,060,448 (-)Ensembl
Ensembl Acc Id: ENSMUST00000164532   ⟹   ENSMUSP00000132486
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1563,802,791 - 63,869,818 (-)Ensembl
GRCm38.p6 Ensembl1563,930,942 - 63,997,969 (-)Ensembl
Ensembl Acc Id: ENSMUST00000226129
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1563,892,090 - 63,932,277 (-)Ensembl
GRCm38.p6 Ensembl1564,020,241 - 64,060,428 (-)Ensembl
Ensembl Acc Id: ENSMUST00000226675   ⟹   ENSMUSP00000154205
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1563,816,243 - 63,932,179 (-)Ensembl
GRCm38.p6 Ensembl1563,944,394 - 64,060,330 (-)Ensembl
Ensembl Acc Id: ENSMUST00000227024   ⟹   ENSMUSP00000153790
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1563,815,128 - 63,932,269 (-)Ensembl
GRCm38.p6 Ensembl1563,943,279 - 64,060,420 (-)Ensembl
Ensembl Acc Id: ENSMUST00000227118
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1563,828,177 - 63,833,392 (-)Ensembl
GRCm38.p6 Ensembl1563,956,328 - 63,961,543 (-)Ensembl
Ensembl Acc Id: ENSMUST00000228226   ⟹   ENSMUSP00000154320
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1563,802,793 - 63,932,192 (-)Ensembl
GRCm38.p6 Ensembl1563,930,944 - 64,060,343 (-)Ensembl
Ensembl Acc Id: ENSMUST00000228908   ⟹   ENSMUSP00000154547
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1563,811,555 - 63,932,327 (-)Ensembl
GRCm38.p6 Ensembl1563,939,706 - 64,060,478 (-)Ensembl
RefSeq Acc Id: NM_001360035   ⟹   NP_001346964
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,800,943 - 63,869,915 (-)NCBI
GRCm381563,929,094 - 63,998,066 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001360036   ⟹   NP_001346965
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,800,943 - 63,932,297 (-)NCBI
GRCm381563,929,094 - 64,060,448 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001360037   ⟹   NP_001346966
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,800,943 - 63,932,297 (-)NCBI
GRCm381563,929,094 - 64,060,448 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001360038   ⟹   NP_001346967
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,800,943 - 63,931,613 (-)NCBI
GRCm381563,929,094 - 64,059,764 (-)NCBI
Sequence:
RefSeq Acc Id: NM_144846   ⟹   NP_659095
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,800,943 - 63,932,297 (-)NCBI
GRCm381563,929,094 - 64,060,448 (-)NCBI
MGSCv371563,760,649 - 63,892,010 (-)RGD
Celera1565,431,654 - 65,563,033 (-)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006520762   ⟹   XP_006520825
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,884,958 (-)NCBI
GRCm381563,930,942 - 63,998,195 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006520763   ⟹   XP_006520826
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,932,387 (-)NCBI
GRCm381563,930,942 - 64,060,524 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006520764   ⟹   XP_006520827
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,884,958 (-)NCBI
GRCm381563,930,942 - 63,998,232 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006520765   ⟹   XP_006520828
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,869,925 (-)NCBI
GRCm381563,930,942 - 63,998,076 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006520766   ⟹   XP_006520829
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,884,958 (-)NCBI
GRCm381563,930,942 - 64,013,109 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011245564   ⟹   XP_011243866
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,932,387 (-)NCBI
GRCm381563,930,942 - 64,060,524 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248468   ⟹   XP_030104328
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,932,627 (-)NCBI
GRCm381563,930,942 - 64,060,778 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248469   ⟹   XP_030104329
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,932,627 (-)NCBI
GRCm381563,930,942 - 64,060,778 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248470   ⟹   XP_030104330
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,932,593 (-)NCBI
GRCm381563,930,942 - 64,060,769 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248471   ⟹   XP_030104331
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,932,577 (-)NCBI
GRCm381563,930,942 - 64,060,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248472   ⟹   XP_030104332
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,932,532 (-)NCBI
GRCm381563,930,942 - 64,060,683 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248473   ⟹   XP_030104333
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,884,958 (-)NCBI
GRCm381563,930,942 - 63,998,140 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248474   ⟹   XP_030104334
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,932,387 (-)NCBI
GRCm381563,930,942 - 64,060,430 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248475   ⟹   XP_030104335
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,932,623 (-)NCBI
GRCm381563,930,942 - 64,060,774 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248476   ⟹   XP_030104336
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,932,387 (-)NCBI
GRCm381563,930,942 - 64,060,518 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248477   ⟹   XP_030104337
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,932,387 (-)NCBI
GRCm381563,930,942 - 64,060,417 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248478   ⟹   XP_030104338
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,884,958 (-)NCBI
GRCm381563,930,942 - 64,013,109 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036159326   ⟹   XP_036015219
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,932,478 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036159327   ⟹   XP_036015220
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391563,802,791 - 63,932,502 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001346964 (Get FASTA)   NCBI Sequence Viewer  
  NP_001346965 (Get FASTA)   NCBI Sequence Viewer  
  NP_001346966 (Get FASTA)   NCBI Sequence Viewer  
  NP_001346967 (Get FASTA)   NCBI Sequence Viewer  
  NP_659095 (Get FASTA)   NCBI Sequence Viewer  
  XP_006520825 (Get FASTA)   NCBI Sequence Viewer  
  XP_006520826 (Get FASTA)   NCBI Sequence Viewer  
  XP_006520827 (Get FASTA)   NCBI Sequence Viewer  
  XP_006520828 (Get FASTA)   NCBI Sequence Viewer  
  XP_006520829 (Get FASTA)   NCBI Sequence Viewer  
  XP_011243866 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104328 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104329 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104330 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104331 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104332 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104333 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104334 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104335 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104336 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104337 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104338 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015219 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015220 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH11343 (Get FASTA)   NCBI Sequence Viewer  
  BAC25731 (Get FASTA)   NCBI Sequence Viewer  
  BAC35858 (Get FASTA)   NCBI Sequence Viewer  
  EDL29352 (Get FASTA)   NCBI Sequence Viewer  
  EDL29353 (Get FASTA)   NCBI Sequence Viewer  
  EDL29354 (Get FASTA)   NCBI Sequence Viewer  
  EDL29355 (Get FASTA)   NCBI Sequence Viewer  
  EDL29356 (Get FASTA)   NCBI Sequence Viewer  
  EDL29357 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000066359
  ENSMUSP00000066359.5
  ENSMUSP00000132486
  ENSMUSP00000132486.2
  ENSMUSP00000154320
  ENSMUSP00000154320.2
GenBank Protein Q921M7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_659095   ⟸   NM_144846
- Peptide Label: isoform 1
- UniProtKB: Q921M7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006520829   ⟸   XM_006520766
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_006520828   ⟸   XM_006520765
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006520825   ⟸   XM_006520762
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006520827   ⟸   XM_006520764
- Peptide Label: isoform X4
- UniProtKB: Q921M7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006520826   ⟸   XM_006520763
- Peptide Label: isoform X4
- UniProtKB: Q921M7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011243866   ⟸   XM_011245564
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: NP_001346966   ⟸   NM_001360037
- Peptide Label: isoform 1
- UniProtKB: Q921M7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001346965   ⟸   NM_001360036
- Peptide Label: isoform 1
- UniProtKB: Q921M7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001346967   ⟸   NM_001360038
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001346964   ⟸   NM_001360035
- Peptide Label: isoform 1
- UniProtKB: Q921M7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_030104329   ⟸   XM_030248469
- Peptide Label: isoform X2
RefSeq Acc Id: XP_030104328   ⟸   XM_030248468
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030104335   ⟸   XM_030248475
- Peptide Label: isoform X4
- UniProtKB: Q921M7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_030104331   ⟸   XM_030248471
- Peptide Label: isoform X4
- UniProtKB: Q921M7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_030104330   ⟸   XM_030248470
- Peptide Label: isoform X3
RefSeq Acc Id: XP_030104332   ⟸   XM_030248472
- Peptide Label: isoform X4
- UniProtKB: Q921M7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_030104336   ⟸   XM_030248476
- Peptide Label: isoform X5
RefSeq Acc Id: XP_030104334   ⟸   XM_030248474
- Peptide Label: isoform X4
- UniProtKB: Q921M7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_030104337   ⟸   XM_030248477
- Peptide Label: isoform X5
RefSeq Acc Id: XP_030104338   ⟸   XM_030248478
- Peptide Label: isoform X6
RefSeq Acc Id: XP_030104333   ⟸   XM_030248473
- Peptide Label: isoform X4
- UniProtKB: Q921M7 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSMUSP00000132486   ⟸   ENSMUST00000164532
Ensembl Acc Id: ENSMUSP00000154320   ⟸   ENSMUST00000228226
Ensembl Acc Id: ENSMUSP00000153790   ⟸   ENSMUST00000227024
Ensembl Acc Id: ENSMUSP00000154205   ⟸   ENSMUST00000226675
Ensembl Acc Id: ENSMUSP00000066359   ⟸   ENSMUST00000063838
Ensembl Acc Id: ENSMUSP00000154547   ⟸   ENSMUST00000228908
RefSeq Acc Id: XP_036015220   ⟸   XM_036159327
- Peptide Label: isoform X5
RefSeq Acc Id: XP_036015219   ⟸   XM_036159326
- Peptide Label: isoform X4
- UniProtKB: Q921M7 (UniProtKB/Swiss-Prot)
Protein Domains
CYRIA/CYRIB Rac1 binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q921M7-F1-model_v2 AlphaFold Q921M7 1-324 view protein structure

Promoters
RGD ID:6825565
Promoter ID:MM_KWN:18611
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:UC007VZE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361563,829,101 - 63,829,757 (-)MPROMDB
RGD ID:6825564
Promoter ID:MM_KWN:18614
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung
Transcripts:NM_144846,   UC007VZG.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361563,891,716 - 63,892,997 (-)MPROMDB
RGD ID:8683852
Promoter ID:EPDNEW_M19957
Type:initiation region
Name:Fam49b_1
Description:Mus musculus family with sequence similarity 49, member B , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19958  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381563,998,082 - 63,998,142EPDNEW
RGD ID:8683854
Promoter ID:EPDNEW_M19958
Type:initiation region
Name:Fam49b_2
Description:Mus musculus family with sequence similarity 49, member B , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19957  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381564,060,389 - 64,060,449EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1923520 AgrOrtholog
Ensembl Genes ENSMUSG00000022378 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000063838 ENTREZGENE
  ENSMUST00000063838.11 UniProtKB/Swiss-Prot
  ENSMUST00000164532 ENTREZGENE
  ENSMUST00000164532.3 UniProtKB/Swiss-Prot
  ENSMUST00000228226 ENTREZGENE
  ENSMUST00000228226.2 UniProtKB/Swiss-Prot
InterPro DUF1394 UniProtKB/Swiss-Prot
  FAM49 UniProtKB/Swiss-Prot
KEGG Report mmu:223601 UniProtKB/Swiss-Prot
MGD MGI:1923520 ENTREZGENE
NCBI Gene Cyrib ENTREZGENE
PANTHER PTHR12422 UniProtKB/Swiss-Prot
Pfam DUF1394 UniProtKB/Swiss-Prot
PhenoGen Cyrib PhenoGen
UniProt A0A2I3BPH9_MOUSE UniProtKB/TrEMBL
  A0A2I3BQK1_MOUSE UniProtKB/TrEMBL
  A0A2I3BRN5_MOUSE UniProtKB/TrEMBL
  FA49B_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Cyrib  CYFIP related Rac1 interactor B  0910001A06Rik  RIKEN cDNA 0910001A06 gene  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 0910001A06Rik  RIKEN cDNA 0910001A06 gene  Cyrib  CYFIP related Rac1 interactor B  Symbol and/or name change 5135510 APPROVED
2020-03-25 Cyrib  CYFIP related Rac1 interactor B  Fam49b  family with sequence similarity 49, member B  Symbol and/or name change 5135510 APPROVED