Kng1 (kininogen 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Kng1 (kininogen 1) Mus musculus
Analyze
Symbol: Kng1
Name: kininogen 1
RGD ID: 1332018
MGI Page MGI
Description: Predicted to enable cysteine-type endopeptidase inhibitor activity; hormone activity; and protease binding activity. Predicted to be involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; negative regulation of blood coagulation; and vasodilation. Located in collagen-containing extracellular matrix. Is expressed in yolk sac. Human ortholog(s) of this gene implicated in hereditary angioedema and high molecular weight kininogen deficiency. Orthologous to human KNG1 (kininogen 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: H-kin; H-kininigen; kininogen-1; Kng; L-ki; L-kininogen; MGC123437
RGD Orthologs
Human
Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391622,876,970 - 22,900,828 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1622,876,615 - 22,900,828 (+)EnsemblGRCm39 Ensembl
GRCm381623,058,220 - 23,082,078 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1623,057,865 - 23,082,078 (+)EnsemblGRCm38mm10GRCm38
MGSCv371623,058,373 - 23,082,151 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361622,973,682 - 22,997,021 (+)NCBIMGSCv36mm8
Celera1623,617,404 - 23,641,056 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1613.88NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1-naphthyl isothiocyanate  (ISO)
1-octadec-9-enoylglycero-3-phosphate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2,6-dinitrotoluene  (ISO)
3',5'-cyclic AMP  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-methylcholanthrene  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-fluorouracil  (ISO)
6-oxoprostaglandin F1alpha  (ISO)
7,12-dimethyltetraphene  (ISO)
7-ketocholesterol  (ISO)
acetylsalicylic acid  (ISO)
aconitine  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alpha-linolenic acid  (ISO)
ammonium chloride  (ISO)
arachidonic acid  (ISO)
benazepril  (ISO)
benzo[a]pyrene  (EXP,ISO)
bexarotene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bucladesine  (ISO)
cadmium atom  (ISO)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
capsaicin  (EXP,ISO)
captopril  (ISO)
carbon nanotube  (EXP)
carnosic acid  (EXP)
chlorpromazine  (ISO)
chlorpyrifos  (EXP)
chromium trinitrate  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP)
cobalt atom  (EXP)
compound 48/80  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (EXP)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP,ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
doxorubicin  (EXP,ISO)
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  (ISO)
enalapril  (ISO)
flurbiprofen  (ISO)
flutamide  (ISO)
formaldehyde  (EXP)
genistein  (EXP)
gentamycin  (ISO)
glafenine  (ISO)
GW 4064  (ISO)
Hexachloro-1,3-butadiene  (ISO)
histamine  (ISO)
icatibant  (EXP,ISO)
indometacin  (ISO)
irinotecan  (ISO)
isoflavones  (ISO)
kainic acid  (ISO)
ketamine  (EXP)
lead diacetate  (ISO)
lead(0)  (ISO)
lidocaine  (ISO)
lipopolysaccharide  (ISO)
losartan  (ISO)
m-xylene  (ISO)
manganese(II) chloride  (ISO)
meloxicam  (ISO)
menadione  (ISO)
mepyramine  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
methyltestosterone  (ISO)
N,O-dimethyltyramine  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nafamostat  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nicotine  (ISO)
nimesulide  (ISO)
nitric oxide  (EXP,ISO)
nitrofen  (ISO)
nitroprusside  (ISO)
O-methyleugenol  (ISO)
olanzapine  (ISO)
oryzalin  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
PD123319  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
perindopril  (ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP)
potassium chloride  (ISO)
potassium chromate  (EXP)
potassium dichromate  (EXP)
Pranoprofen  (EXP)
progesterone  (ISO)
propiconazole  (EXP)
propofol  (ISO)
prostaglandin E2  (ISO)
prostaglandin I2  (ISO)
quartz  (ISO)
quercetin  (ISO)
ramipril  (ISO)
ramiprilat  (ISO)
serotonin  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (EXP)
staurosporine  (ISO)
stigmasterol  (ISO)
streptozocin  (ISO)
sulforaphane  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (EXP,ISO)
tolcapone  (ISO)
tributylstannane  (EXP)
trichloroethene  (EXP)
Triptolide  (ISO)
U-73122  (ISO)
valproic acid  (EXP,ISO)
valsartan  (ISO)
vinclozolin  (ISO)
vinyl carbamate  (EXP)
wortmannin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Genetic basis of total kininogen deficiency in Williams' trait. Cheung PP, etal., J Biol Chem. 1993 Nov 5;268(31):23361-5.
2. Genetic kininogen deficiency contributes to aortic aneurysm formation but not to atherosclerosis. Kaschina E, etal., Physiol Genomics 2004 Sep 16;19(1):41-9. Epub 2004 Jul 06.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. The kallikrein-kinin system: current and future pharmacological targets. Moreau ME, etal., J Pharmacol Sci. 2005 Sep;99(1):6-38.
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Effect of Chronic Blockade of the Kallikrein-Kinin System on the Development of Hypertension in Rats. Rhaleb NE, etal., Hypertension 2001 Jan;37(1):121-128.
12. Analysis of 14 candidate genes for diabetic nephropathy on chromosome 3q in European populations: strongest evidence for association with a variant in the promoter region of the adiponectin gene. Vionnet N, etal., Diabetes. 2006 Nov;55(11):3166-74.
Additional References at PubMed
PMID:7937138   PMID:9199253   PMID:10349636   PMID:10583403   PMID:11042159   PMID:11076861   PMID:12023845   PMID:12477932   PMID:14506238   PMID:14610273   PMID:15134344   PMID:15489334  
PMID:16141072   PMID:16141073   PMID:16837654   PMID:16944957   PMID:17330941   PMID:18000168   PMID:18329172   PMID:19423573   PMID:19673938   PMID:20116414   PMID:21873635   PMID:22936657  
PMID:22936662   PMID:24688027   PMID:26153520   PMID:28071719   PMID:29122754   PMID:29540224   PMID:29618843   PMID:29771909   PMID:30358441   PMID:32325033   PMID:32707450   PMID:33706097  
PMID:33827130   PMID:37142655  


Genomics

Comparative Map Data
Kng1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391622,876,970 - 22,900,828 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1622,876,615 - 22,900,828 (+)EnsemblGRCm39 Ensembl
GRCm381623,058,220 - 23,082,078 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1623,057,865 - 23,082,078 (+)EnsemblGRCm38mm10GRCm38
MGSCv371623,058,373 - 23,082,151 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361622,973,682 - 22,997,021 (+)NCBIMGSCv36mm8
Celera1623,617,404 - 23,641,056 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1613.88NCBI
KNG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383186,717,359 - 186,744,410 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3186,717,348 - 186,744,410 (+)EnsemblGRCh38hg38GRCh38
GRCh373186,435,148 - 186,462,199 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363187,917,814 - 187,944,437 (+)NCBINCBI36Build 36hg18NCBI36
Celera3184,871,536 - 184,898,662 (+)NCBICelera
Cytogenetic Map3q27.3NCBI
HuRef3183,844,775 - 183,871,713 (+)NCBIHuRef
CHM1_13186,399,036 - 186,425,781 (+)NCBICHM1_1
T2T-CHM13v2.03189,539,122 - 189,566,165 (+)NCBIT2T-CHM13v2.0
Kng1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,317,354 - 91,340,148 (-)NCBIGRCr8
mRatBN7.21177,812,757 - 77,835,555 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1177,812,752 - 77,835,555 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1186,563,196 - 86,585,990 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01179,201,040 - 79,223,873 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01178,277,516 - 78,300,314 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01181,421,672 - 81,444,466 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1181,421,676 - 81,444,621 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01184,502,772 - 84,541,046 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41180,008,752 - 80,031,601 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11180,066,341 - 80,089,190 (-)NCBI
Celera1176,684,934 - 76,707,727 (-)NCBICelera
Cytogenetic Map11q23NCBI

Variants

.
Variants in Kng1
839 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:657
Count of miRNA genes:379
Interacting mature miRNAs:425
Transcripts:ENSMUST00000023589, ENSMUST00000039492, ENSMUST00000089902, ENSMUST00000125790, ENSMUST00000136778
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301970Heal11_mwound healing/regeneration 11 (mouse)Not determined16124263853Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
4142460Nilac10_mnicotine induced locomotor activity 10 (mouse)Not determined16713690629225471Mouse
4141179Ipng3_mimprinted postnatal growth 3 (mouse)Not determined2277525257594076Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
11565820Vasr1_mvariability in acoustic startle response 1 (mouse)161969865726368664Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16464631438646414Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined16988163143881631Mouse
1301575Tanidd3_mtally ho associated non-insulin dependednt diabetes mellitus 3 (mouse)Not determined16122897739Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162001932985600826Mouse
1301384Dice1_mdetermination of interleukin 4 commitment 1 (mouse)Not determined16128434358Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16577525239775440Mouse
10402497Lmr23_mleishmaniasis resistance 23 (mouse)Not determined16129674200Mouse
10412289Ppsl_mplasma P-selectin levels (mouse)Not determined16130814572Mouse
4141468Nhdlq10_mnon-HDL QTL 10 (mouse)Not determined16124263853Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16577525239775440Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161552290949523112Mouse
1301559Bbaa19_mB.burgdorferi-associated arthritis 19 (mouse)Not determined16130066977Mouse
1300534Bmd15_mbone mineral density 15 (mouse)Not determined162193838355938574Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16822605242226052Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16577525239775440Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16577525239775440Mouse
4141010Bbq1_mbrain and behavior QTL 1 (mouse)Not determined16647700935021216Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161480292148803032Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse

Markers in Region
D17999  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381623,081,715 - 23,081,835UniSTSGRCm38
GRCm381622,985,711 - 22,985,831UniSTSGRCm38
MGSCv371622,985,784 - 22,985,904UniSTSGRCm37
MGSCv371623,081,788 - 23,081,908UniSTSGRCm37
Celera1623,640,693 - 23,640,813UniSTS
Celera1623,545,652 - 23,545,772UniSTS
Cytogenetic Map16B1UniSTS
Whitehead_YAC16 UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001102411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001102412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001425115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_023125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA277668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK005547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY462058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY660571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC108936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY463622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D84415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D84435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000023589   ⟹   ENSMUSP00000023589
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1622,877,094 - 22,898,756 (+)Ensembl
GRCm38.p6 Ensembl1623,058,344 - 23,080,006 (+)Ensembl
Ensembl Acc Id: ENSMUST00000039492   ⟹   ENSMUSP00000040485
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1622,877,000 - 22,900,828 (+)Ensembl
GRCm38.p6 Ensembl1623,058,250 - 23,082,078 (+)Ensembl
Ensembl Acc Id: ENSMUST00000089902   ⟹   ENSMUSP00000087346
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1622,877,143 - 22,898,920 (+)Ensembl
GRCm38.p6 Ensembl1623,058,393 - 23,080,170 (+)Ensembl
Ensembl Acc Id: ENSMUST00000125790   ⟹   ENSMUSP00000121701
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1622,876,615 - 22,886,619 (+)Ensembl
GRCm38.p6 Ensembl1623,057,865 - 23,067,869 (+)Ensembl
RefSeq Acc Id: NM_001102411   ⟹   NP_001095881
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391622,877,050 - 22,898,756 (+)NCBI
GRCm381623,058,300 - 23,080,006 (+)NCBI
MGSCv371623,058,373 - 23,082,151 (+)RGD
Celera1623,617,404 - 23,641,056 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001102412   ⟹   NP_001095882
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391622,877,050 - 22,898,756 (+)NCBI
GRCm381623,058,300 - 23,080,006 (+)NCBI
MGSCv371623,058,373 - 23,082,151 (+)RGD
Celera1623,617,404 - 23,641,056 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001425115   ⟹   NP_001412044
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391622,877,085 - 22,900,442 (+)NCBI
RefSeq Acc Id: NM_023125   ⟹   NP_075614
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391622,877,050 - 22,900,828 (+)NCBI
GRCm381623,058,300 - 23,082,078 (+)NCBI
MGSCv371623,058,373 - 23,082,151 (+)RGD
Celera1623,617,404 - 23,641,056 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006521812   ⟹   XP_006521875
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391622,876,970 - 22,898,765 (+)NCBI
GRCm381623,058,220 - 23,080,015 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006521813   ⟹   XP_006521876
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391622,876,970 - 22,898,765 (+)NCBI
GRCm381623,058,220 - 23,080,015 (+)NCBI
Sequence:
RefSeq Acc Id: NP_075614   ⟸   NM_023125
- Peptide Label: isoform 2 precursor
- UniProtKB: O08677 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001095881   ⟸   NM_001102411
- Peptide Label: isoform 1 precursor
- UniProtKB: Q91XK5 (UniProtKB/Swiss-Prot),   Q6S9I1 (UniProtKB/Swiss-Prot),   Q32MX7 (UniProtKB/Swiss-Prot),   O08676 (UniProtKB/Swiss-Prot),   O08677 (UniProtKB/Swiss-Prot),   A0A0R4J038 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001095882   ⟸   NM_001102412
- Peptide Label: isoform 3 precursor
- UniProtKB: D3YTY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006521876   ⟸   XM_006521813
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006521875   ⟸   XM_006521812
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000121701   ⟸   ENSMUST00000125790
Ensembl Acc Id: ENSMUSP00000087346   ⟸   ENSMUST00000089902
Ensembl Acc Id: ENSMUSP00000040485   ⟸   ENSMUST00000039492
Ensembl Acc Id: ENSMUSP00000023589   ⟸   ENSMUST00000023589
RefSeq Acc Id: NP_001412044   ⟸   NM_001425115
- Peptide Label: isoform 4 precursor
Protein Domains
Cystatin kininogen-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08677-F1-model_v2 AlphaFold O08677 1-661 view protein structure

Promoters
RGD ID:6827196
Promoter ID:MM_KWN:20569
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:ENSMUST00000115346,   NM_001102411,   NM_001102412,   OTTMUST00000063826,   OTTMUST00000063829,   OTTMUST00000064625
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361623,058,291 - 23,058,791 (+)MPROMDB
RGD ID:8685832
Promoter ID:EPDNEW_M20946
Type:initiation region
Name:Kng1_1
Description:Mus musculus kininogen 1 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381623,058,335 - 23,058,395EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1097705 AgrOrtholog
Ensembl Genes ENSMUSG00000022875 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000023589 ENTREZGENE
  ENSMUST00000023589.15 UniProtKB/TrEMBL
  ENSMUST00000039492 ENTREZGENE
  ENSMUST00000039492.14 UniProtKB/Swiss-Prot
  ENSMUST00000089902 ENTREZGENE
  ENSMUST00000089902.8 UniProtKB/TrEMBL
  ENSMUST00000125790.8 UniProtKB/TrEMBL
Gene3D-CATH 3.10.450.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cystatin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cystatin_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kininogen UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kininogen-type_cystatin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kininogen_Fetuin_HRG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_inh_cystat_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16644 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1097705 ENTREZGENE
NCBI Gene 16644 ENTREZGENE
PANTHER FETUIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KININOGEN-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cystatin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB KNG1 RGD
PhenoGen Kng1 PhenoGen
PRINTS KININOGEN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CYSTATIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CYSTATIN_KININOGEN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00043 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54403 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J038 ENTREZGENE, UniProtKB/TrEMBL
  D3YTY9 ENTREZGENE, UniProtKB/TrEMBL
  D3Z2B2_MOUSE UniProtKB/TrEMBL
  KNG1_MOUSE UniProtKB/Swiss-Prot
  O08676 ENTREZGENE
  O08677 ENTREZGENE
  Q32MX7 ENTREZGENE
  Q6S9I1 ENTREZGENE
  Q91XK5 ENTREZGENE
UniProt Secondary O08676 UniProtKB/Swiss-Prot
  Q32MX7 UniProtKB/Swiss-Prot
  Q6S9I1 UniProtKB/Swiss-Prot
  Q91XK5 UniProtKB/Swiss-Prot