Itfg2 (integrin alpha FG-GAP repeat containing 2)

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Gene: Itfg2 (integrin alpha FG-GAP repeat containing 2) Mus musculus

Analyze

Symbol:

Itfg2

Name:

integrin alpha FG-GAP repeat containing 2

RGD ID:

1323662

MGI Page

MGI

Description:

Acts upstream of or within germinal center B cell differentiation. Located in cytosol and nucleoplasm. Orthologous to human ITFG2 (integrin alpha FG-GAP repeat containing 2).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

2700050P07Rik; AI646725; integrin-alpha FG-GAP repeat-containing protein 2; KICSTOR complex protein ITFG2

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	128,386,407 - 128,401,873 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	128,386,407 - 128,401,894 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	128,409,047 - 128,424,927 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	128,409,444 - 128,424,931 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	128,359,462 - 128,374,928 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	128,375,063 - 128,390,529 (-)	NCBI		MGSCv36	mm8
Celera	6	130,086,278 - 130,101,735 (-)	NCBI		Celera
Cytogenetic Map	6	F3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Hyperphosphatemic Familial Tumoral Calcinosis 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (ISO)

1,2-dimethylhydrazine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

CGP 52608 (ISO)

chloroacetaldehyde (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (ISO)

ethanol (EXP,ISO)

fenofibrate (ISO)

folic acid (EXP)

fulvestrant (ISO)

gentamycin (ISO)

ifosfamide (ISO)

monosodium L-glutamate (EXP)

resveratrol (ISO)

SB 431542 (ISO)

tetrachloromethane (ISO)

trichostatin A (ISO)

valproic acid (EXP,ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to amino acid starvation (ISO)

cellular response to glucose starvation (ISO)

germinal center B cell differentiation (IMP)

negative regulation of TORC1 signaling (ISO)

regulation of TOR signaling (IBA)

Cellular Component

cytosol (IDA)

KICSTOR complex (IBA,ISO)

lysosomal membrane (ISO)

lysosome (IEA)

membrane (IEA)

nucleoplasm (IDA)

Molecular Function

molecular_function (ND)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal B cell activation (IAGP)

abnormal humoral immune response (IAGP)

abnormal splenocyte physiology (IAGP)

decreased B cell number (IAGP)

decreased IgE level (IAGP)

decreased IgG1 level (IAGP)

decreased IgG2a level (IAGP)

decreased IgG2b level (IAGP)

decreased IgG3 level (IAGP)

decreased lymphocyte cell number (IAGP)

decreased spleen germinal center number (IAGP)

decreased T follicular helper cell number (IAGP)

enlarged lymph nodes (IAGP)

enlarged spleen (IAGP)

increased anti-double stranded DNA antibody level (IAGP)

increased anti-nuclear antigen antibody level (IAGP)

increased B cell number (IAGP)

increased double-negative T cell number (IAGP)

increased IgG2a level (IAGP)

increased IgM level (IAGP)

increased mean corpuscular hemoglobin concentration (IEA)

increased susceptibility to systemic lupus erythematosus (IAGP)

increased urine protein level (IAGP)

iris synechia (IEA)

preweaning lethality, incomplete penetrance (IEA)

spleen hyperplasia (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:10922068	PMID:11042159	PMID:11076861	PMID:12477932	PMID:14610273	PMID:15782199	PMID:16141072	PMID:16141073	PMID:17967808	PMID:18799693
PMID:21267068	PMID:21873635	PMID:23997217

Genomics

Comparative Map Data

Itfg2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	128,386,407 - 128,401,873 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	128,386,407 - 128,401,894 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	128,409,047 - 128,424,927 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	128,409,444 - 128,424,931 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	128,359,462 - 128,374,928 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	128,375,063 - 128,390,529 (-)	NCBI		MGSCv36	mm8
Celera	6	130,086,278 - 130,101,735 (-)	NCBI		Celera
Cytogenetic Map	6	F3	NCBI

ITFG2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	2,812,668 - 2,859,791 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	12	2,812,622 - 2,859,791 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	2,921,834 - 2,968,957 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	2,792,124 - 2,804,367 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	12	4,535,723 - 4,548,173 (+)	NCBI		Celera
Cytogenetic Map	12	p13.33	NCBI
HuRef	12	2,779,353 - 2,791,802 (+)	NCBI		HuRef
CHM1_1	12	2,921,024 - 2,933,474 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	2,818,668 - 2,865,802 (+)	NCBI		T2T-CHM13v2.0

Itfg2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	161,684,249 - 161,698,315 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	161,684,249 - 161,698,422 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	167,914,670 - 167,927,901 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	4	163,697,608 - 163,710,839 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	4	162,331,644 - 162,344,875 (-)	NCBI	Rnor_WKY
Rnor_6.0	4	161,730,643 - 161,744,281 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	161,730,641 - 161,743,896 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	226,936,184 - 226,949,437 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	165,429,677 - 165,442,930 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	165,675,379 - 165,690,062 (-)	NCBI
Celera	4	150,386,454 - 150,399,708 (-)	NCBI		Celera
Cytogenetic Map	4	q42	NCBI

Itfg2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955429	18,356,642 - 18,372,928 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955429	18,356,642 - 18,372,928 (+)	NCBI	ChiLan1.0	ChiLan1.0

ITFG2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	12	2,865,297 - 2,889,752 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	2,865,297 - 2,877,555 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	12	2,933,227 - 2,980,509 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

ITFG2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	41,933,741 - 41,944,464 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	41,934,575 - 41,944,472 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	4,739,698 - 4,750,438 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	42,291,904 - 42,302,645 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	42,291,904 - 42,302,596 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	42,233,426 - 42,244,162 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	42,203,098 - 42,213,849 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	4,099,392 - 4,110,145 (+)	NCBI		UU_Cfam_GSD_1.0

Itfg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	106,025,311 - 106,039,230 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936606	3,144,602 - 3,158,890 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936606	3,144,616 - 3,158,825 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ITFG2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	67,291,772 - 67,305,607 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	67,292,901 - 67,306,208 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	69,579,204 - 69,592,320 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ITFG2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	2,877,864 - 2,891,223 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	2,877,997 - 2,890,477 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666063	5,425,387 - 5,438,866 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Itfg2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624860	147,308 - 180,132 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624860	147,476 - 175,754 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	441
Count of miRNA genes:	355
Interacting mature miRNAs:	378
Transcripts:	ENSMUST00000001559, ENSMUST00000133994, ENSMUST00000142615
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
26884414	Bzwq12_m	bi-zygomatic width QTL 12, 16 week (mouse)					6	3400000	139076998	Mouse
10412157	Fl1n_m	fatty liver 1 in NSY (mouse)			Not determined		6	45290993	128811995	Mouse
4142259	Tabw2_m	tally ho associated body weight 2 (mouse)			Not determined			46912919	136400690	Mouse
25314320	Histh5_m	histamine hypersensitivity 5 (mouse)					6	48696934	148351498	Mouse
13506930	Recrq9_m	recombination rate in male meiosis QTL 9 (mouse)					6	73476983	134676963	Mouse
10043864	T2dm4sa_m	type 2 diabetes mellitus 4 in SMXA RI mice (mouse)			Not determined		6	83690851	146954059	Mouse
11353842	Bmiq4_m	body mass index QTL 4 (mouse)					6	92584287	146330736	Mouse
1301292	Cfbw2_m	cystic fibrosis body weight 2 (mouse)			Not determined		6	94981612	128981699	Mouse
11040599	Lmr4b_m	leishmaniasis resistance 4b (mouse)					6	96324286	130324483	Mouse
1300704	Cia3_m	collagen induced arthritis QTL 3 (mouse)			Not determined		6	96324286	130324483	Mouse
4141940	W6q5_m	weight 6 weeks QTL 5 (mouse)			Not determined			96632912	146535124	Mouse
4142416	Egq11_m	early growth QTL 11 (mouse)			Not determined			96632912	146535124	Mouse
1357555	Tesq2_m	testis weight QTL 2 (mouse)			Not determined		6	96632912	146535124	Mouse
10043923	Bhr7_m	bronchial hyperresponsiveness 7 (mouse)			Not determined		6	98219814	132219938	Mouse
1301518	Bbaa5_m	B.burgdorferi-associated arthritis 5 (mouse)			Not determined		6	98483798	145881170	Mouse
1301923	Lith6_m	lithogenic gene 6 (mouse)			Not determined		6	98694477	132694676	Mouse
1301915	Chab3_m	cholesterol absorption 3 (mouse)			Not determined		6	98908709	132916997	Mouse
1302131	Bmd8_m	bone mineral density 8 (mouse)			Not determined		6	99132089	133132228	Mouse
1300887	Pabr1_m	plasma apolipoprotein B (human) regulator 1 (mouse)			Not determined		6	103754405	136400690	Mouse
1357806	Aaj3_m	anxiety in A/J 3 (mouse)			Not determined		6	104480321	136400690	Mouse
10412207	Cypr5_m	cytokine production 5 (mouse)			Not determined		6	110815180	144815323	Mouse
13463481	Mcvq14_m	mean corpuscular volume QTL 14 (mouse)					6	111142448	145142541	Mouse
11252138	Clas1_m	carcinogen-induced lung adenoma susceptibility 1 (mouse)					6	112246918	146954059	Mouse
4140980	Mvwf2_m	modifier of von Willebrand factor 2 (mouse)			Not determined			114345693	145601739	Mouse
1301658	Radpf3_m	radiation pulmonary fibrosis 3 (mouse)			Not determined		6	115219814	146330736	Mouse
4141889	Qui_m	quinine sensitivity, taste (mouse)			Not determined			115546805	149549364	Mouse
4141194	Cyx_m	cycloheximide tasting (mouse)			Not determined			115546805	149549364	Mouse
4141295	Rua_m	raffinose acetate tasting (mouse)			Not determined			115546805	149549364	Mouse
1301927	Etohcta6_m	ethanol conditioned taste aversion 6 (mouse)			Not determined		6	115578005	149578150	Mouse
1301083	Bhr5_m	bronchial hyperresponsiveness 5 (mouse)			Not determined		6	115694477	132578150	Mouse
4141064	Ath37_m	atherosclerosis 37 (mouse)			Not determined		6	116641858	128495988	Mouse
4142079	Skmw15_m	skeletal muscle weight 15 (mouse)			Not determined		6	116829851	149588044	Mouse
1301152	Athsq2_m	atherosclerosis susceptibility QTL 2 (mouse)			Not determined		6	117059949	149588044	Mouse
1301804	Bulb2_m	bulb size 2 (mouse)			Not determined		6	120416806	149588044	Mouse
10449436	Pas17_m	pulmonary adenoma susceptibility 17 (mouse)					6	124334273	145601739	Mouse
1302089	Wta2_m	weight adult 2 (mouse)			Not determined		6	125269523	149588044	Mouse
4141611	Btts_m	bitterness tasting (mouse)			Not determined		6	125333609	134096586	Mouse
10412134	Cmv4_m	cytomegalovirus resistance 4 (mouse)			Not determined		6	127815180	136022150	Mouse
10449437	Pas15_m	pulmonary adenoma susceptibility 15 (mouse)					6	128180868	149588044	Mouse

Markers in Region

AI646725

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	128,409,741 - 128,409,840	UniSTS	GRCm38
MGSCv37	6	128,359,759 - 128,359,858	UniSTS	GRCm37
Celera	6	130,086,575 - 130,086,674	UniSTS
Cytogenetic Map	6	F3	UniSTS
Whitehead/MRC_RH	6	1294.63	UniSTS

UniSTS:224369

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	128,417,435 - 128,417,600	UniSTS	GRCm38
MGSCv37	6	128,367,453 - 128,367,618	UniSTS	GRCm37
Celera	6	130,094,315 - 130,094,480	UniSTS
Cytogenetic Map	6	F3	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133927	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC116573	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK019208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK019211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK134630	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK142721	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK147728	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK159637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK183090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK185688	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC014833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000001559 ⟹ ENSMUSP00000001559

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	128,386,407 - 128,401,894 (-)	Ensembl
GRCm38.p6 Ensembl	6	128,409,444 - 128,424,931 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000133994

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	128,392,593 - 128,401,893 (-)	Ensembl
GRCm38.p6 Ensembl	6	128,415,630 - 128,424,930 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000142615 ⟹ ENSMUSP00000145111

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	128,386,496 - 128,401,881 (-)	Ensembl
GRCm38.p6 Ensembl	6	128,409,533 - 128,424,918 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000203026 ⟹ ENSMUSP00000145388

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	128,390,603 - 128,401,876 (-)	Ensembl
GRCm38.p6 Ensembl	6	128,413,640 - 128,424,913 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000203195

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	128,388,549 - 128,391,340 (-)	Ensembl
GRCm38.p6 Ensembl	6	128,411,586 - 128,414,377 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000203374 ⟹ ENSMUSP00000145323

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	128,387,175 - 128,401,832 (-)	Ensembl
GRCm38.p6 Ensembl	6	128,410,212 - 128,424,869 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000203853 ⟹ ENSMUSP00000145282

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	128,389,970 - 128,401,875 (-)	Ensembl
GRCm38.p6 Ensembl	6	128,413,007 - 128,424,912 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000203984 ⟹ ENSMUSP00000144837

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	128,386,461 - 128,387,343 (-)	Ensembl
GRCm38.p6 Ensembl	6	128,409,498 - 128,410,380 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000204362

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	128,387,221 - 128,387,648 (-)	Ensembl
GRCm38.p6 Ensembl	6	128,410,258 - 128,410,685 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000204467

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	128,399,747 - 128,401,881 (-)	Ensembl
GRCm38.p6 Ensembl	6	128,422,784 - 128,424,918 (-)	Ensembl

RefSeq Acc Id:

NM_133927 ⟹ NP_598688

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	128,386,407 - 128,401,873 (-)	NCBI
GRCm38	6	128,409,444 - 128,424,910 (-)	NCBI
MGSCv37	6	128,359,462 - 128,374,928 (-)	RGD
Celera	6	130,086,278 - 130,101,735 (-)	RGD
cM Map	6		ENTREZGENE

Sequence:

show sequence

CTTCCGGTTCGGTGGCCTGACACGCGTGCACGGCTGTCCTGAGGGCTCGGGGGTCGTTTTGGTG
CAGTGGCCCGGCACCTCAGCCCTCCAGAGTGCCATGAGGTCGGTTAGTTATGTGCAGCGCGTGG
CGCTGGATTTCAGCGGGAGTCTCTTCCCGCACGCCATCTGCCTCGGAGACGTGGATAACGACGC
GTTAAATGAGCTAGTTGTGGGAGACACCAGCGGGAAACTGTCCGTGTATAAGAATGACGACAGC
CGGCCATGGCTTACCTGCATGTGCCAGGGAATGTTGACTTGTGTTGGGGTCGGAGATGTCTGTA
ATAAAGGGAAGAACCTGGTGGTAGCAGTCAGCGCAGAAGGCTGGCTGCACTTGTTTGACCTGAC
ACCCACCAAGGCTCTGGATGCCTCTGGGCACCATGAGACACTTGGAGAGGAGCAGCGACCTGTC
TTCAAGCAGCACATCCCGGCCAACACAAAGGTCATGCTGATCAGCGACATCGATGGAGATGGGT
GTTACGAGCTGGTGGTAGGATACACAGACCGTGTGGTGCGGGCCTTCCGCTGGGAAGAACTGGC
TGAGGGGCCTGAACACCTGGCAGGGCAGTTGGTGTCCCTCAAGAAGTGGATGCTGGAGGGTCAG
GTAGACAGTCTCTCTGTGACCCCAGGGCCTCTGGGTGTGCCTGAGTTGGTTGTGTCGCAGCCAG
GGTGTGCTTATGCAGTTCTGCTGTGCACCTGGAACAAGGACACTGGCTCCCCTCCTGCCTCTGA
GGAGGCCACAGGAGACAGTAGGGAGACCCCAGCTGCCCGAGATGTAGTCCTGCACCAGACATCT
GGCCGGATCCACAACAAGAACGTCTCCACTCACCTAATTGGCAACATCAGACAAGGTCATAACC
CTGAAGGTGGTAACGCAGGCCTCTTCGCCCTGTGCACCCTGGATGGGACACTGAAGCTGATGCA
GGAAGCAGACAAGTTGCTGTGGTCTGTGCAGGTGGATCACCAGCTTTTTGCCCTAGAGAAGCTG
GATGTCACGGGCAATGGGCTTGAGGAGGTGGTAGCTTGTGCCTGGGATGGACAGACATATATCA
TCGATCACAACCGCACCGTTGTGCGCTTCCAAGTGGATGAAAATATCCGTGCCTTCTGTGCAGG
CCAGTACGCCTGCAAAGAGGGCCGCAACAGTCCCTGCTTGGTATATGTCACCTTCAATCAGAAG
ATCTACGTGTACTGGGAGGTGCAGCTGGAGCGCATGGAGTCCACTAACCTTCTGAAGCTGCTGG
AGGCTGAGCCCGAGTACCACCGCCTACTGCAGGAGCTGCGTGTGGATCCTGAAGATCTCCCTGC
AGTCTGTACCCTGCTTCATCAGACTCTCTACCATCCGGACCAGCCACTACAGTGTACCCCCTCA
AGCTTCCAGGACCCCACCTAGCTGGGCTCGACCACTTAGCTGGTGAAGGATCCTTCCGAGCCCC
CAACCCTACCCCAGAGCGATCCATGACCTTGGAGGATGGGGAGTGTGTATTACAGAGGAAGGAG
CAGAACTGGGTTCTCAGAGAGGATGGATGTGCCCCCCCCCCCCCCCCGAGAGCCTGTGATGAAG
AGATCCATCGGTTGCCCCTCTGCTCGTGGCTCCTTCTCATGCTCCCTGCTCTCACTGCAGGAAA
CCGACTTGTGTGTGAGACAAGGCAGCAAACCTTTGCTATGTTCCAACACCTGAAAGGCTTCAGG
CCTGAGGAACTGAGGGAGCATGGGGTGAGCCCCCCTCCCCCTGCTGAGTGCCGATTTTCACAGC
ATAGCTCCAGGCAGCTGACACTCGCAGTTATTGCAGGAATGAACGGCAGAGTATTTATTCTTTT
AGGGTATTTTCCTGTCTCATCTTCCTGTGTTCTTCCATTTACTGAAGCAACTAGGTCAGGGCTT
TCTCATTTTGTCATCATCTCTCTCTGGTTTTGTTTTTGTTTGTTGGTTTTGTTTTGTATGTCTC
TGTGTGCAAAGGAGGAACCAGGGGTGTTCACACACCAGCCAAGTGCTCTGCCATTCAGCTGTAT
CCAGCACTGCCGTTCTCTAAAGTACCGTGCTGCTTGAGAGCCTCACCCACCTGCTTCCCAAACA
TGACTGCCTGTCGGAAACTAGATGCTCACAGTTTGTCTTACATGATGGTGCACCAGTGTACTCC
CAGTTCTTGAGAGAAAGATCATGAGTCCAAAGCCAGCCAAGGCTCCATAGCAAGTTTGAGACCA
GCGTGGGTCACATTTGGAGATCTGATCTCAAATAAAACAAAAAGGCGTTAACAATCTGAAAAAA
AAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_598688	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH14833	(Get FASTA)	NCBI Sequence Viewer
	BAE22217	(Get FASTA)	NCBI Sequence Viewer
	BAE28098	(Get FASTA)	NCBI Sequence Viewer
	BAE35251	(Get FASTA)	NCBI Sequence Viewer
	EDK99883	(Get FASTA)	NCBI Sequence Viewer
	EDK99884	(Get FASTA)	NCBI Sequence Viewer
	EDK99885	(Get FASTA)	NCBI Sequence Viewer
	Q91WI7	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_598688 ⟸ NM_133927

- UniProtKB:

Q8R148 (UniProtKB/Swiss-Prot), Q91WI7 (UniProtKB/Swiss-Prot), A0A6P5PUK6 (UniProtKB/TrEMBL), A0A8C6I1I8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRSVSYVQRVALDFSGSLFPHAICLGDVDNDALNELVVGDTSGKLSVYKNDDSRPWLTCMCQGM
LTCVGVGDVCNKGKNLVVAVSAEGWLHLFDLTPTKALDASGHHETLGEEQRPVFKQHIPANTKV
MLISDIDGDGCYELVVGYTDRVVRAFRWEELAEGPEHLAGQLVSLKKWMLEGQVDSLSVTPGPL
GVPELVVSQPGCAYAVLLCTWNKDTGSPPASEEATGDSRETPAARDVVLHQTSGRIHNKNVSTH
LIGNIRQGHNPEGGNAGLFALCTLDGTLKLMQEADKLLWSVQVDHQLFALEKLDVTGNGLEEVV
ACAWDGQTYIIDHNRTVVRFQVDENIRAFCAGQYACKEGRNSPCLVYVTFNQKIYVYWEVQLER
MESTNLLKLLEAEPEYHRLLQELRVDPEDLPAVCTLLHQTLYHPDQPLQCTPSSFQDPT

hide sequence

RefSeq Acc Id:

ENSMUSP00000144837 ⟸ ENSMUST00000203984

RefSeq Acc Id:

ENSMUSP00000145282 ⟸ ENSMUST00000203853

RefSeq Acc Id:

ENSMUSP00000145323 ⟸ ENSMUST00000203374

RefSeq Acc Id:

ENSMUSP00000145388 ⟸ ENSMUST00000203026

RefSeq Acc Id:

ENSMUSP00000001559 ⟸ ENSMUST00000001559

RefSeq Acc Id:

ENSMUSP00000145111 ⟸ ENSMUST00000142615

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q91WI7-F1-model_v2	AlphaFold	Q91WI7	1-443	view protein structure

Promoters

RGD ID:

6839513

Promoter ID:

MM_KWN:47790

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

ENSMUST00000001559, OTTMUST00000058632, OTTMUST00000058633, UC009EDP.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	6	128,374,576 - 128,375,377 (-)	MPROMDB

RGD ID:

6891140

Promoter ID:

EPDNEW_M9021

Type:

multiple initiation site

Name:

Itfg2_1

Description:

Mus musculus integrin alpha FG-GAP repeat containing 2 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	6	128,424,921 - 128,424,981	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1915450	AgrOrtholog
Ensembl Genes	ENSMUSG00000001518	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000001559	ENTREZGENE
	ENSMUSP00000001559.9	UniProtKB/Swiss-Prot
	ENSMUSP00000144837.2	UniProtKB/TrEMBL
	ENSMUSP00000145111.2	UniProtKB/TrEMBL
	ENSMUSP00000145282.2	UniProtKB/TrEMBL
	ENSMUSP00000145323.2	UniProtKB/TrEMBL
	ENSMUSP00000145388.2	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000001559	ENTREZGENE
	ENSMUST00000001559.11	UniProtKB/Swiss-Prot
	ENSMUST00000142615.4	UniProtKB/TrEMBL
	ENSMUST00000203026.2	UniProtKB/TrEMBL
	ENSMUST00000203374.3	UniProtKB/TrEMBL
	ENSMUST00000203853.3	UniProtKB/TrEMBL
	ENSMUST00000203984.2	UniProtKB/TrEMBL
InterPro	Integrin_alpha_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	KICSTOR_ITFG2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
KEGG Report	mmu:101142	UniProtKB/Swiss-Prot
MGD	MGI:1915450	ENTREZGENE
NCBI Gene	101142	ENTREZGENE
PANTHER	KICSTOR COMPLEX PROTEIN ITFG2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR16317	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Itfg2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Itfg2	PhenoGen
Superfamily-SCOP	SSF50978	UniProtKB/TrEMBL
	SSF69318	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0N4SUV5_MOUSE	UniProtKB/TrEMBL
	A0A0N4SVX2_MOUSE	UniProtKB/TrEMBL
	A0A0N4SW06_MOUSE	UniProtKB/TrEMBL
	A0A0N4SW62_MOUSE	UniProtKB/TrEMBL
	A0A6P5PUK6	ENTREZGENE
	A0A8C6I1I8	ENTREZGENE
	ITFG2_MOUSE	UniProtKB/Swiss-Prot
	Q3TWL5_MOUSE	UniProtKB/TrEMBL
	Q8R148	ENTREZGENE
	Q91WI7	ENTREZGENE
UniProt Secondary	Q3UYJ5	UniProtKB/Swiss-Prot
	Q8R148	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Mammalian Phenotype