Hspa9 (heat shock protein 9) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Hspa9 (heat shock protein 9) Mus musculus
Analyze
Symbol: Hspa9
Name: heat shock protein 9
RGD ID: 1323452
MGI Page MGI
Description: Enables enzyme binding activity. Involved in iron-sulfur cluster assembly; negative regulation of hematopoietic stem cell differentiation; and negative regulation of hemopoiesis. Acts upstream of or within protein export from nucleus. Located in mitochondrion. Is active in mitochondrial matrix. Is expressed in early conceptus; germ cell of gonad; heart; and liver. Human ortholog(s) of this gene implicated in Parkinson's disease and autosomal dominant sideroblastic anemia 4. Orthologous to human HSPA9 (heat shock protein family A (Hsp70) member 9).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 74kDa; 75 kDa glucose-regulated protein; C; C3H-specific antigen; Csa; GRP; GRP-75; Grp75; heat shock 70 kDa protein 9; heat shock protein 9A; heat shock protein cognate 74; heat shock protein, 74 kDa, A; heat shock protein, A; Hs; Hsc7; Hsc74; Hsp; Hsp74; Hsp74a; Hspa9a; mo; Mortalin; mot-; Mot-2; Mot2; mthsp; Mthsp70; p66 MOT; PBP; Pbp74; peptide-binding protein 74; stress-70 protein, mitochondrial
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Hspa9-ps1  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391835,070,467 - 35,087,404 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1835,070,467 - 35,087,410 (-)EnsemblGRCm39 Ensembl
GRCm381834,937,414 - 34,954,351 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1834,937,414 - 34,954,357 (-)EnsemblGRCm38mm10GRCm38
MGSCv371835,097,068 - 35,114,005 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361835,063,405 - 35,080,297 (-)NCBIMGSCv36mm8
Celera1835,391,734 - 35,408,655 (-)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1818.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-anisomycin  (ISO)
(1->4)-beta-D-glucan  (EXP)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(R)-adrenaline  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
1H-pyrazole  (EXP)
2,2,2-tetramine  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2-hydroxypropanoic acid  (ISO)
2-nitrofluorene  (ISO)
26-hydroxycholesterol  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-nitropropanoic acid  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxynon-2-enal  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
7H-xanthine  (ISO)
9H-xanthine  (ISO)
acetamide  (ISO)
acetylleucyl-leucyl-norleucinal  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP,ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-lapachone  (ISO)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (EXP)
casticin  (EXP)
chloropicrin  (ISO)
chloroprene  (ISO)
chlorpyrifos  (EXP)
chromium(6+)  (EXP)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (EXP)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dieldrin  (ISO)
diethylstilbestrol  (EXP,ISO)
dioxygen  (EXP)
disodium selenite  (ISO)
dopamine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
efavirenz  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
fenofibrate  (EXP)
fenthion  (EXP)
ferric ammonium citrate  (ISO)
finasteride  (ISO)
flufenoxuron  (EXP)
fluorescein 5-isothiocyanate  (ISO)
flutamide  (ISO)
folic acid  (EXP,ISO)
FR900359  (ISO)
gallium nitrate  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glucose  (ISO)
gold atom  (EXP)
gold(0)  (EXP)
hemin  (ISO)
homocysteine  (ISO)
hydrazine  (ISO)
indirubin-3'-monoxime  (ISO)
indometacin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isotretinoin  (ISO)
ivermectin  (EXP,ISO)
L-ascorbic acid  (ISO)
lead diacetate  (ISO)
lead nitrate  (ISO)
lead(II) chloride  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
melatonin  (ISO)
mercury dichloride  (ISO)
metformin  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methylmercury chloride  (EXP,ISO)
methylparaben  (ISO)
mevinphos  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (ISO)
nefazodone  (ISO)
nickel dichloride  (ISO)
Nutlin-3  (ISO)
ochratoxin A  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorododecanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
phlorizin  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phosgene  (EXP)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
potassium dichromate  (ISO)
pterostilbene  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP,ISO)
rotenone  (EXP,ISO)
sarin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
Soman  (ISO)
streptozocin  (ISO)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
testosterone  (EXP)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP,ISO)
thiram  (ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
troglitazone  (EXP)
tunicamycin  (EXP,ISO)
urethane  (ISO)
valproic acid  (ISO)
vanillic acid  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
withaferin A  (ISO)
Withanone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO,TAS)
mitochondrial matrix  (IDA,ISO)
mitochondrial nucleoid  (IEA,ISO)
mitochondrion  (HDA,IBA,IDA,ISO)
myelin sheath  (HDA)
nucleolus  (IEA)
nucleus  (ISO,ISS)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis. Burbulla LF, etal., Hum Mol Genet. 2010 Nov 15;19(22):4437-52. Epub 2010 Sep 2.
2. Mortalin inhibition in experimental Parkinson's disease. Chiasserini D, etal., Mov Disord. 2011 Aug 1;26(9):1639-47. doi: 10.1002/mds.23647. Epub 2011 May 3.
3. Mutational screening of the mortalin gene (HSPA9) in Parkinson's disease. De Mena L, etal., J Neural Transm. 2009 Oct;116(10):1289-93. Epub 2009 Aug 6.
4. Proteomic identification of a stress protein, mortalin/mthsp70/GRP75: relevance to Parkinson disease. Jin J, etal., Mol Cell Proteomics. 2006 Jul;5(7):1193-204. Epub 2006 Mar 24.
5. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
6. Proteomic analysis of synovial fibroblast-like synoviocytes from rheumatoid arthritis. Li XJ, etal., Clin Exp Rheumatol. 2013 Jul-Aug;31(4):552-8. Epub 2013 Jun 5.
7. Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery. Maio N and Rouault TA, Biochim Biophys Acta. 2015 Jun;1853(6):1493-512. doi: 10.1016/j.bbamcr.2014.09.009. Epub 2014 Sep 19.
8. Cloning of rat grp75, an hsp70-family member, and its expression in normal and ischemic brain. Massa SM, etal., J Neurosci Res. 1995 Apr 15;40(6):807-19.
9. MGDs mouse GO annotations MGD data from the GO Consortium
10. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
11. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
12. Mortalin is regulated by APOE in hippocampus of AD patients and by human APOE in TR mice. Osorio C, etal., Neurobiol Aging. 2007 Dec;28(12):1853-62. Epub 2006 Oct 16.
13. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
14. Mouse MP Annotation Import Pipeline RGD automated import pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Unlocking the presequence import pathway. Schulz C, etal., Trends Cell Biol. 2015 May;25(5):265-75. doi: 10.1016/j.tcb.2014.12.001. Epub 2014 Dec 23.
18. Mortalin: a protein associated with progression of Parkinson disease? Shi M, etal., J Neuropathol Exp Neurol. 2008 Feb;67(2):117-24.
Additional References at PubMed
PMID:3292542   PMID:7523108   PMID:7577442   PMID:7684501   PMID:7692847   PMID:7693662   PMID:7698336   PMID:7813609   PMID:7865888   PMID:7896880   PMID:7988674   PMID:8245417  
PMID:8262211   PMID:8344392   PMID:8454632   PMID:8586457   PMID:8806442   PMID:9780007   PMID:10087208   PMID:10087302   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861  
PMID:11092755   PMID:11850063   PMID:11900485   PMID:12377383   PMID:12477932   PMID:12520002   PMID:12646231   PMID:12904583   PMID:12931191   PMID:14610273   PMID:14728808   PMID:14993262  
PMID:15747579   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16196101   PMID:16327803   PMID:16916647   PMID:16959763   PMID:17110338   PMID:17376863   PMID:17634366   PMID:17967808  
PMID:18448421   PMID:18614015   PMID:18614564   PMID:18799693   PMID:19423573   PMID:19578372   PMID:20624969   PMID:21123823   PMID:21267068   PMID:21565611   PMID:21677750   PMID:21873635  
PMID:22673621   PMID:22794259   PMID:23395614   PMID:23665500   PMID:23937658   PMID:24243970   PMID:24324263   PMID:24457600   PMID:24491357   PMID:24614889   PMID:25330109   PMID:25550197  
PMID:25737280   PMID:26095919   PMID:26370502   PMID:26514267   PMID:26584622   PMID:26702583   PMID:27034005   PMID:27160897   PMID:27746211   PMID:28344592   PMID:28376086   PMID:28378742  
PMID:28671696   PMID:28846746   PMID:29292841   PMID:29459677   PMID:29669786   PMID:29913563   PMID:30107089   PMID:30196744   PMID:30333137   PMID:30457570   PMID:30550785   PMID:30562941  
PMID:30590033   PMID:30590615   PMID:30595499   PMID:30713523   PMID:31162944   PMID:31767755   PMID:32294449   PMID:32325033   PMID:32434143   PMID:32554809   PMID:33230847   PMID:34756890  
PMID:34810178   PMID:34943961   PMID:35012549   PMID:35344886   PMID:35988140   PMID:36108743   PMID:36114006   PMID:36293380   PMID:36417873   PMID:36427672   PMID:36656174   PMID:36822087  
PMID:36841836   PMID:37142655   PMID:37669129   PMID:38138960   PMID:38467701   PMID:38981469  


Genomics

Comparative Map Data
Hspa9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391835,070,467 - 35,087,404 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1835,070,467 - 35,087,410 (-)EnsemblGRCm39 Ensembl
GRCm381834,937,414 - 34,954,351 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1834,937,414 - 34,954,357 (-)EnsemblGRCm38mm10GRCm38
MGSCv371835,097,068 - 35,114,005 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361835,063,405 - 35,080,297 (-)NCBIMGSCv36mm8
Celera1835,391,734 - 35,408,655 (-)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1818.8NCBI
HSPA9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385138,553,756 - 138,575,401 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5138,553,756 - 138,575,675 (-)EnsemblGRCh38hg38GRCh38
GRCh375137,889,445 - 137,911,090 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365137,918,923 - 137,939,014 (-)NCBINCBI36Build 36hg18NCBI36
Build 345137,918,923 - 137,939,014NCBI
Celera5134,012,432 - 134,033,183 (-)NCBICelera
Cytogenetic Map5q31.2NCBI
HuRef5133,080,998 - 133,101,775 (-)NCBIHuRef
CHM1_15137,322,949 - 137,343,701 (-)NCBICHM1_1
T2T-CHM13v2.05139,080,003 - 139,101,647 (-)NCBIT2T-CHM13v2.0
Hspa9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81826,810,004 - 26,832,958 (-)NCBIGRCr8
mRatBN7.21826,536,131 - 26,554,294 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1826,535,798 - 26,554,292 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1826,663,496 - 26,681,657 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01827,427,270 - 27,445,422 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01826,762,158 - 26,780,315 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01827,731,072 - 27,749,235 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1827,731,072 - 27,749,235 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01827,441,164 - 27,459,327 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41827,419,614 - 27,437,031 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11827,445,403 - 27,463,728 (-)NCBI
Celera1826,272,806 - 26,290,966 (-)NCBICelera
Cytogenetic Map18p12NCBI
Hspa9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554181,915,985 - 1,931,017 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554181,915,985 - 1,931,017 (+)NCBIChiLan1.0ChiLan1.0
HSPA9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24133,830,305 - 133,851,364 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15131,969,859 - 131,990,917 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05133,934,859 - 133,955,048 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15140,064,207 - 140,084,551 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5140,064,207 - 140,084,551 (-)Ensemblpanpan1.1panPan2
HSPA9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11126,122,917 - 26,142,458 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1126,121,499 - 26,142,434 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1124,890,286 - 24,911,642 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01126,977,471 - 26,998,872 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1126,978,054 - 26,998,797 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11125,684,920 - 25,708,764 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01125,507,197 - 25,528,814 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01126,171,421 - 26,192,815 (-)NCBIUU_Cfam_GSD_1.0
Hspa9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213153,895,035 - 153,908,810 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365317,702,695 - 7,716,380 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365317,702,186 - 7,716,428 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSPA9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2140,515,253 - 140,531,857 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12140,515,239 - 140,532,164 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22146,230,077 - 146,246,697 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HSPA9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12341,230,675 - 41,251,177 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2341,231,364 - 41,251,150 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603436,634,038 - 36,655,489 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hspa9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474331,324,085 - 31,345,695 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474331,324,085 - 31,345,681 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hspa9
602 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:725
Count of miRNA genes:480
Interacting mature miRNAs:566
Transcripts:ENSMUST00000025217, ENSMUST00000172829, ENSMUST00000173701, ENSMUST00000173806
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558743Kcal1_mkilocalorie 1 (mouse)Not determined181901887453018992Mouse
1302163Bmd16_mbone mineral density 16 (mouse)Not determined182966791463668060Mouse
11532716Sluc41c_msusceptibility to lung cancer 41c (mouse)182261991456620127Mouse
11532715Sluc41b_msusceptibility to lung cancer 41b (mouse)182261991456620127Mouse
11532710Sluc41a_msusceptibility to lung cancer 41a (mouse)182261991456620127Mouse
25823171Hrsq10_mhost response to SARS QTL 10, D4% weight (mouse)182724111558827077Mouse
11532709Sluc41_msusceptibility to lung cancer 41 (mouse)182095369457590708Mouse
1301400Lmr13_mleishmaniasis resistance 13 (mouse)Not determined182810938062109518Mouse
25823174Hrsq11_mhost response to SARS QTL 11, log titer (mouse)182724111558827077Mouse
1300638Im7_mimmunoregulatory 7 (mouse)Not determined181901887453018992Mouse
1558873Hrtfm7_mheart failure modifier 7 (mouse)Not determined18808696442087106Mouse
25823173Hrsq12_mhost response to SARS QTL 12, hemorrhage (mouse)182489588178339555Mouse
1300994Pvcan3_mprotection against vaginal candidiasis 3 (mouse)Not determined181619964050199776Mouse
1301570Sluc14_msusceptibility to lung cancer 14 (mouse)Not determined182261991456620127Mouse
13504732Cath6_mcarotid atherosclerosis 6 (mouse)181363712647637126Mouse
1558849W3q15_mweight 3 weeks QTL 15 (mouse)Not determined18504111961272643Mouse
12880412V125Dq12_mvitamin D active form serum level QTL 12 (mouse)183023306764233067Mouse
1300877Adip8_madiposity 8 (mouse)Not determined182261991456620127Mouse
4141857Mhysq5_mmale hybrid sterility QTL 5 (mouse)Not determined2813060462130739Mouse
1300685Scc5_mcolon tumor susceptibility 5 (mouse)Not determined183198848065988629Mouse
1301307Phospq1_mphospholipid QTL 1 (mouse)Not determined181813970452139859Mouse
1301950Otx2m1_morthodenticle homolog 2 (Drosophila) modifier 1 (mouse)Not determined182156868236187740Mouse
1357690Vtbt19_mvertebral trabecular bone trait 19 (mouse)Not determined183309104367091221Mouse
4142031Moen1_mmodifier of engrailed QTL 1 (mouse)Not determined182411556058115730Mouse
12904950Smmq3_msoleus muscle mass QTL 3 (mouse)182605687560056875Mouse
25823167Hrsq5_mhost response to SARS QTL 5, D3% weight (mouse)182724111558827077Mouse
1357603Mom3_mmodifier of Min 3 (mouse)Not determined181403002367098962Mouse
13463476Hctq8_mhematocrit QTL 8 (mouse)182121758055217727Mouse
27226723Tibw9_mtibia width 9, proximal, 16 week (mouse)18320000060933072Mouse

Markers in Region
Hspa9a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381834,938,633 - 34,938,735UniSTSGRCm38
MGSCv371835,098,287 - 35,098,389UniSTSGRCm37
Celera1835,392,953 - 35,393,055UniSTS
Cytogenetic Map18CUniSTS
cM Map1815.0UniSTS
Hspa9  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381834,938,586 - 34,938,723UniSTSGRCm38
Celera1835,392,906 - 35,393,043UniSTS
Cytogenetic Map18CUniSTS
cM Map1815.0UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC131675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK133501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP769296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY146974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D11089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D17556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D17666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L06896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000025217   ⟹   ENSMUSP00000025217
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1835,070,467 - 35,087,410 (-)Ensembl
GRCm38.p6 Ensembl1834,937,414 - 34,954,357 (-)Ensembl
Ensembl Acc Id: ENSMUST00000235244
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1835,080,586 - 35,081,177 (-)Ensembl
GRCm38.p6 Ensembl1834,947,533 - 34,948,124 (-)Ensembl
Ensembl Acc Id: ENSMUST00000236908
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1835,071,749 - 35,073,915 (-)Ensembl
GRCm38.p6 Ensembl1834,938,696 - 34,940,862 (-)Ensembl
Ensembl Acc Id: ENSMUST00000237289
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1835,081,225 - 35,084,626 (-)Ensembl
GRCm38.p6 Ensembl1834,948,172 - 34,951,573 (-)Ensembl
Ensembl Acc Id: ENSMUST00000237399
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1835,071,320 - 35,072,363 (-)Ensembl
GRCm38.p6 Ensembl1834,938,267 - 34,939,310 (-)Ensembl
RefSeq Acc Id: NM_010481   ⟹   NP_034611
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391835,070,467 - 35,087,404 (-)NCBI
GRCm381834,937,414 - 34,954,351 (-)ENTREZGENE
MGSCv371835,097,068 - 35,114,005 (-)RGD
Celera1835,391,734 - 35,408,655 (-)RGD
cM Map18 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_034611   ⟸   NM_010481
- UniProtKB: Q7TSZ0 (UniProtKB/Swiss-Prot),   Q3V015 (UniProtKB/Swiss-Prot),   Q3UVN1 (UniProtKB/Swiss-Prot),   Q3TW93 (UniProtKB/Swiss-Prot),   Q9CQ05 (UniProtKB/Swiss-Prot),   P38647 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000025217   ⟸   ENSMUST00000025217

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P38647-F1-model_v2 AlphaFold P38647 1-679 view protein structure

Promoters
RGD ID:13677400
Promoter ID:EPDNEW_M22849
Type:initiation region
Name:Hspa9_1
Description:Mus musculus heat shock protein 9 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381834,954,344 - 34,954,404EPDNEW
RGD ID:6848706
Promoter ID:MM_TRO:4701
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4
Transcripts:MTR001282.18.454.2
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361835,105,821 - 35,106,321 (-)MPROMDB
RGD ID:6849254
Promoter ID:MM_XEF:3415
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4,   ES_Cell,   Kidney,   MEF_B4
Transcripts:NM_001001229,   NM_001018892,   NM_001042193,   NM_001054809,   NM_001055272,   NM_001073018,   NM_001086158,   NM_001086697,   NM_001136842,   NM_001158267,   NM_001159056,   NM_001159129,   NM_001160048,   NM_001176153,   NM_071890,   NM_079017,   NM_118561,   NM_119952,   NM_120996,   NM_124369,   NM_201326,   NM_211254
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361835,111,869 - 35,112,369 (-)MPROMDB
RGD ID:6829261
Promoter ID:MM_KWN:24910
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_010481,   XM_001476281_GM3300
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361835,112,866 - 35,115,612 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96245 AgrOrtholog
Ensembl Genes ENSMUSG00000024359 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000025217 ENTREZGENE
  ENSMUST00000025217.11 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1270.10 UniProtKB/Swiss-Prot
  3.30.30.30 UniProtKB/Swiss-Prot
  3.30.420.40 UniProtKB/Swiss-Prot
InterPro ATPase_NBD UniProtKB/Swiss-Prot
  Chaperone_DnaK UniProtKB/Swiss-Prot
  Heat_shock_70_CS UniProtKB/Swiss-Prot
  HSP70_C_sf UniProtKB/Swiss-Prot
  HSP70_peptide-bd_sf UniProtKB/Swiss-Prot
  Hsp_70_fam UniProtKB/Swiss-Prot
KEGG Report mmu:15526 UniProtKB/Swiss-Prot
MGD MGI:96245 ENTREZGENE
NCBI Gene 15526 ENTREZGENE
PANTHER PTHR19375 UniProtKB/Swiss-Prot
  STRESS-70 PROTEIN, MITOCHONDRIAL UniProtKB/Swiss-Prot
Pfam HSP70 UniProtKB/Swiss-Prot
PhenoGen Hspa9 PhenoGen
PRINTS HEATSHOCK70 UniProtKB/Swiss-Prot
PROSITE HSP70_1 UniProtKB/Swiss-Prot
  HSP70_2 UniProtKB/Swiss-Prot
  HSP70_3 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF100920 UniProtKB/Swiss-Prot
  SSF53067 UniProtKB/Swiss-Prot
UniProt GRP75_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TW93 ENTREZGENE
  Q3UVN1 ENTREZGENE
  Q3V015 ENTREZGENE
  Q7TSZ0 ENTREZGENE
  Q9CQ05 ENTREZGENE
UniProt Secondary Q3TW93 UniProtKB/Swiss-Prot
  Q3UVN1 UniProtKB/Swiss-Prot
  Q3V015 UniProtKB/Swiss-Prot
  Q7TSZ0 UniProtKB/Swiss-Prot
  Q9CQ05 UniProtKB/Swiss-Prot