Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sik3 | Mouse | Spondyloepimetaphyseal Dysplasia, Krakow Type | | ISO | SIK3 (Homo sapiens) | 7240710 | | OMIM | | |
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sik3 | Mouse | Spondyloepimetaphyseal Dysplasia, Krakow Type | | ISO | SIK3 (Homo sapiens) | 7240710 | | OMIM | | |
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# | Reference Title | Reference Citation |
1. | MGDs mouse GO annotations | MGD data from the GO Consortium |
2. | Mouse MP Annotation Import Pipeline | RGD automated import pipeline |
3. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
4. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:8889548 | PMID:10349636 | PMID:11042159 | PMID:11076861 | PMID:11217851 | PMID:12466851 | PMID:12477932 | PMID:12520002 | PMID:14610273 | PMID:14621295 | PMID:15489334 | PMID:16141072 |
PMID:16141073 | PMID:16959763 | PMID:18799693 | PMID:20564261 | PMID:21267068 | PMID:21565611 | PMID:21873635 | PMID:22318228 | PMID:22662228 | PMID:23033494 | PMID:23393134 | PMID:24061540 |
PMID:24743732 | PMID:25060954 | PMID:25088745 | PMID:25513882 | PMID:25619259 | PMID:27009967 | PMID:27806374 | PMID:27920213 | PMID:28671696 | PMID:28706196 | PMID:29227248 | PMID:29941929 |
PMID:30254177 | PMID:30550785 | PMID:30973865 | PMID:31280862 | PMID:31350328 | PMID:31430259 | PMID:31636950 | PMID:31927188 | PMID:32325033 | PMID:32343771 | PMID:33063669 | PMID:33558433 |
PMID:33600797 | PMID:34160349 | PMID:34196217 | PMID:34732767 | PMID:34856199 | PMID:35864266 | PMID:35997995 | PMID:36477539 | PMID:36862513 | PMID:36877841 | PMID:37321371 | PMID:37356786 |
PMID:37477881 | PMID:37715891 | PMID:38355793 | PMID:39030684 |
Sik3 (Mus musculus - house mouse) |
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SIK3 (Homo sapiens - human) |
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Sik3 (Rattus norvegicus - Norway rat) |
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Sik3 (Chinchilla lanigera - long-tailed chinchilla) |
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SIK3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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SIK3 (Canis lupus familiaris - dog) |
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Sik3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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SIK3 (Sus scrofa - pig) |
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SIK3 (Chlorocebus sabaeus - green monkey) |
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Sik3 (Heterocephalus glaber - naked mole-rat) |
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Variants in Sik3
6150 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH126838 |
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AI447252 |
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RH126001 |
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AI846254 |
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AI849445 |
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D9Jpk1 |
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REN72864 |
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AI059153 |
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RefSeq Transcripts | NM_027498 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006510590 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AC116503 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AC122273 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK017789 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK128893 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK129257 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK160324 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC033915 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC058975 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC063268 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC080688 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC082313 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BG229919 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH466522 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CJ171970 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Ensembl Acc Id: | ENSMUST00000120247 ⟹ ENSMUSP00000112859 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSMUST00000120463 ⟹ ENSMUSP00000112749 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSMUST00000122865 ⟹ ENSMUSP00000115981 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSMUST00000126865 ⟹ ENSMUSP00000121032 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSMUST00000138338 ⟹ ENSMUSP00000115805 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSMUST00000153152 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSMUST00000215954 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_027498 ⟹ NP_081774 | ||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006510590 ⟹ XP_006510653 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
Protein RefSeqs | NP_081774 | (Get FASTA) | NCBI Sequence Viewer |
XP_006510653 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAH33915 | (Get FASTA) | NCBI Sequence Viewer |
AAH63268 | (Get FASTA) | NCBI Sequence Viewer | |
AAH80688 | (Get FASTA) | NCBI Sequence Viewer | |
AAH82313 | (Get FASTA) | NCBI Sequence Viewer | |
BAB30934 | (Get FASTA) | NCBI Sequence Viewer | |
BAC98067 | (Get FASTA) | NCBI Sequence Viewer | |
EDL25675 | (Get FASTA) | NCBI Sequence Viewer | |
EDL25676 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSMUSP00000112749 | ||
ENSMUSP00000112749.3 | |||
ENSMUSP00000112859.2 | |||
ENSMUSP00000115805.2 | |||
ENSMUSP00000115981.2 | |||
ENSMUSP00000121032 | |||
ENSMUSP00000121032.2 | |||
GenBank Protein | Q6P4S6 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_081774 ⟸ NM_027498 |
- UniProtKB: | Q8K075 (UniProtKB/Swiss-Prot), Q6ZQ09 (UniProtKB/Swiss-Prot), Q6P4S6 (UniProtKB/Swiss-Prot), Q66JZ5 (UniProtKB/Swiss-Prot), Q641L5 (UniProtKB/Swiss-Prot), E9PU87 (UniProtKB/Swiss-Prot), Q9CYD5 (UniProtKB/Swiss-Prot), F6S7W6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006510653 ⟸ XM_006510590 |
- Peptide Label: | isoform X1 |
- UniProtKB: | F6S7W6 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSMUSP00000115805 ⟸ ENSMUST00000138338 |
Ensembl Acc Id: | ENSMUSP00000121032 ⟸ ENSMUST00000126865 |
Ensembl Acc Id: | ENSMUSP00000112749 ⟸ ENSMUST00000120463 |
Ensembl Acc Id: | ENSMUSP00000112859 ⟸ ENSMUST00000120247 |
Ensembl Acc Id: | ENSMUSP00000115981 ⟸ ENSMUST00000122865 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q6P4S6-F1-model_v2 | AlphaFold | Q6P4S6 | 1-1369 | view protein structure |
RGD ID: | 6845068 | ||||||||
Promoter ID: | MM_KWN:57213 | ||||||||
Type: | CpG-Island | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | MPROMDB | ||||||||
Tissues & Cell Lines: | BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Lung | ||||||||
Transcripts: | ENSMUST00000120247, NM_027498, OTTMUST00000071083 | ||||||||
Position: |
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RGD ID: | 6848384 | ||||||||
Promoter ID: | MM_ACW:50411 | ||||||||
Type: | Non-CpG | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | MPROMDB | ||||||||
Tissues & Cell Lines: | BoneMarrow_2Hour, Brain | ||||||||
Transcripts: | BC033915.CSEP07 | ||||||||
Position: |
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RGD ID: | 8669474 | ||||||||
Promoter ID: | EPDNEW_M12768 | ||||||||
Type: | multiple initiation site | ||||||||
Name: | Sik3_1 | ||||||||
Description: | Mus musculus SIK family kinase 3 , mRNA. | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | MGI:2446296 | AgrOrtholog |
Ensembl Genes | ENSMUSG00000034135 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Ensembl Transcript | ENSMUST00000120247.8 | UniProtKB/TrEMBL |
ENSMUST00000120463 | ENTREZGENE | |
ENSMUST00000120463.9 | UniProtKB/TrEMBL | |
ENSMUST00000122865.2 | UniProtKB/TrEMBL | |
ENSMUST00000126865 | ENTREZGENE | |
ENSMUST00000126865.8 | UniProtKB/Swiss-Prot | |
ENSMUST00000138338.2 | UniProtKB/TrEMBL | |
Gene3D-CATH | Transferase(Phosphotransferase) domain 1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
InterPro | Kinase-like_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Prot_kinase_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Protein_kinase_ATP_BS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Ser/Thr_kinase_AS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SIK | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UBA | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | mmu:70661 | UniProtKB/Swiss-Prot |
MGD | MGI:2446296 | ENTREZGENE |
NCBI Gene | Sik3 | ENTREZGENE |
PANTHER | MAP/MICROTUBULE AFFINITY-REGULATING KINASE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SERINE/THREONINE-PROTEIN KINASE SIK3 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Pkinase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PhenoGen | Sik3 | PhenoGen |
PROSITE | PROTEIN_KINASE_ATP | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PROTEIN_KINASE_DOM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PROTEIN_KINASE_ST | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UBA | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SMART | S_TKc | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Superfamily-SCOP | SSF56112 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | E9PU87 | ENTREZGENE |
F6S7W6 | ENTREZGENE, UniProtKB/TrEMBL | |
F6SBP3_MOUSE | UniProtKB/TrEMBL | |
F6U6U5_MOUSE | UniProtKB/TrEMBL | |
F6U8X4_MOUSE | UniProtKB/TrEMBL | |
Q641L5 | ENTREZGENE | |
Q66JZ5 | ENTREZGENE | |
Q6P4S6 | ENTREZGENE | |
Q6ZQ09 | ENTREZGENE | |
Q8K075 | ENTREZGENE | |
Q9CYD5 | ENTREZGENE | |
SIK3_MOUSE | UniProtKB/Swiss-Prot | |
UniProt Secondary | E9PU87 | UniProtKB/Swiss-Prot |
Q641L5 | UniProtKB/Swiss-Prot | |
Q66JZ5 | UniProtKB/Swiss-Prot | |
Q6ZQ09 | UniProtKB/Swiss-Prot | |
Q8K075 | UniProtKB/Swiss-Prot | |
Q9CYD5 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2024-08-26 | Sik3 | SIK family kinase 3 | BC033915 | cDNA sequence BC033915 | Symbol and/or name updated | 27372883 | PROVISIONAL |
2024-08-21 | BC033915 | cDNA sequence BC033915 | AI849445 | expressed sequence AI849445 | Symbol and/or name change | 5135510 | APPROVED |
2024-08-21 | AI849445 | expressed sequence AI849445 | Sik3 | SIK family kinase 3 | Symbol and/or name change | 5135510 | APPROVED |
2024-08-21 | Sik3 | SIK family kinase 3 | BC033915 | cDNA sequence BC033915 | Symbol and/or name change | 5135510 | APPROVED |
2024-08-21 | BC033915 | cDNA sequence BC033915 | Sik3 | SIK family kinase 3 | Symbol and/or name change | 5135510 | APPROVED |
2016-04-05 | Sik3 | SIK family kinase 3 | 9030204A07Rik | RIKEN cDNA 9030204A07 gene | Data merged from RGD:1607169 | 737654 | PROVISIONAL |