Il17f (interleukin 17F) - Rat Genome Database

Name: Il17f
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Advanced Search (OLGA)

Gene: Il17f (interleukin 17F) Mus musculus

Analyze

Symbol:

Il17f

Name:

interleukin 17F

RGD ID:

1322841

MGI Page

MGI

Description:

Enables cytokine receptor binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in defense response to bacterium and positive regulation of gene expression. Acts upstream of or within positive regulation of cytokine production involved in inflammatory response and positive regulation of transcription by RNA polymerase II. Located in extracellular space. Human ortholog(s) of this gene implicated in chronic mucocutaneous candidiasis. Orthologous to human IL17F (interleukin 17F).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

C87042; expressed sequence C87042; IL-17F; interleukin-17F

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IL17F (interleukin 17F)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Il17f (interleukin 17F)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Il17f (interleukin 17F)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IL17F (interleukin 17F)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	IL17F (interleukin 17F)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Il17f (interleukin 17F)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IL17F (interleukin 17F)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IL17F (interleukin 17F)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Il17f (interleukin 17F)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	IL17A (interleukin 17A)	HGNC	OrthoDB
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Il17f (interleukin 17F)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	IL17F (interleukin 17F)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	il17a/f3 (interleukin 17a/f3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Danio rerio (zebrafish):	il17a/f1 (interleukin 17a/f1)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PhylomeDB)
Caenorhabditis elegans (roundworm):	F25D1.3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	20,847,370 - 20,855,498 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	20,847,370 - 20,860,841 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	20,777,146 - 20,785,274 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	20,777,146 - 20,790,617 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	20,767,227 - 20,774,351 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	20,762,918 - 20,764,663 (-)	NCBI		MGSCv36	mm8
Celera	1	20,651,214 - 20,658,338 (-)	NCBI		Celera
Cytogenetic Map	1	A4	NCBI
cM Map	1	6.49	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Candidiasis, Familial, 6 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,4-phenylenediamine (EXP)

1-fluoro-2,4-dinitrobenzene (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (EXP)

3,4-methylenedioxymethamphetamine (EXP)

4,4'-diaminodiphenylmethane (EXP)

5-aza-2'-deoxycytidine (EXP)

benzalkonium chloride (EXP)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

butanal (ISO)

cadmium atom (EXP)

CGP 52608 (ISO)

digoxigenin (ISO)

dihydroouabain (ISO)

diisononyl phthalate (EXP)

erlotinib hydrochloride (EXP,ISO)

formaldehyde (EXP)

fragrance (ISO)

gentamycin (ISO)

nickel atom (ISO)

paraquat (EXP)

pentachlorophenol (ISO)

prostaglandin E2 (ISO)

resveratrol (ISO)

silicon dioxide (EXP)

silver atom (EXP)

silver(0) (EXP)

simvastatin (ISO)

strophanthidin (ISO)

trichloroethene (ISO)

triptonide (EXP)

Tryptanthrine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adaptive immune response (IEA)

cartilage development (ISO)

defense response to Gram-negative bacterium (IMP)

defense response to Gram-positive bacterium (IMP)

immune system process (IEA)

inflammatory response (IEA)

innate immune response (IEA)

interleukin-17-mediated signaling pathway (ISO)

negative regulation of angiogenesis (ISO)

positive regulation of antimicrobial peptide production (IDA)

positive regulation of chemokine (C-X-C motif) ligand 1 production (ISO)

positive regulation of cytokine production (ISO)

positive regulation of cytokine production involved in inflammatory response (IDA,IGI)

positive regulation of interleukin-6 production (IMP,ISO)

positive regulation of lymphotoxin A production (ISO)

positive regulation of transcription by RNA polymerase II (IDA,IGI)

regulation of granulocyte macrophage colony-stimulating factor production (ISO)

regulation of interleukin-2 production (ISO)

regulation of interleukin-6 production (ISO)

regulation of interleukin-8 production (ISO)

regulation of transforming growth factor beta receptor signaling pathway (ISO)

Cellular Component

extracellular region (IEA)

extracellular space (IDA)

Molecular Function

cytokine activity (ISO)

cytokine binding (ISO)

cytokine receptor binding (IPI)

protein binding (IPI)

protein heterodimerization activity (IDA)

protein homodimerization activity (IDA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

interleukin-23 signaling pathway (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal effector T cell morphology (IAGP)

abnormal immune system physiology (IAGP)

absent gamma-delta T cells (IAGP)

chronic inflammation (IAGP)

decreased acute inflammation (IAGP)

decreased IgG3 level (IAGP)

decreased interleukin-17 secretion (IAGP)

decreased susceptibility to experimental autoimmune encephalomyelitis (IAGP)

decreased susceptibility to induced colitis (IAGP)

enlarged submandibular lymph nodes (IAGP)

increased gamma-delta T cell number (IAGP)

increased IgG1 level (IAGP)

increased IgG2a level (IAGP)

increased IgG2b level (IAGP)

increased susceptibility to bacterial infection (IAGP)

increased susceptibility to infection induced morbidity/mortality (IAGP)

increased T cell proliferation (IAGP)

mouth mucosal ulcer (IAGP)

nasal inflammation (IAGP)

no abnormal phenotype detected (IAGP)

rheumatoid arthritis (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
2.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
3.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10349636	PMID:10725249	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12077275	PMID:12466851	PMID:12477932	PMID:15477493	PMID:16141072	PMID:16141073	PMID:16785495
PMID:16982811	PMID:17218320	PMID:17452998	PMID:17541285	PMID:17911633	PMID:17982105	PMID:18025225	PMID:18411338	PMID:18585065	PMID:18599325	PMID:18723265	PMID:18830271
PMID:18992745	PMID:19017936	PMID:19075395	PMID:19119024	PMID:19144317	PMID:19429865	PMID:19542376	PMID:19596803	PMID:19818650	PMID:19879162	PMID:20042461	PMID:20176744
PMID:20471290	PMID:20493731	PMID:20515925	PMID:20554964	PMID:20562862	PMID:21178015	PMID:21267068	PMID:21278738	PMID:21674483	PMID:21677750	PMID:21703407	PMID:21859896
PMID:21939640	PMID:21982598	PMID:22025514	PMID:22144493	PMID:22179267	PMID:22195749	PMID:22219321	PMID:22244845	PMID:22319003	PMID:22509371	PMID:22723523	PMID:22768215
PMID:22770884	PMID:22942422	PMID:22960222	PMID:22987803	PMID:23285134	PMID:23325004	PMID:23499051	PMID:23686497	PMID:23853597	PMID:23959575	PMID:24040208	PMID:24068935
PMID:24259505	PMID:24530058	PMID:24600029	PMID:24663215	PMID:24706787	PMID:25204502	PMID:25531830	PMID:25642823	PMID:25780043	PMID:25862091	PMID:26038559	PMID:26079807
PMID:26272906	PMID:26377898	PMID:26431948	PMID:26895034	PMID:26965320	PMID:26982366	PMID:27030744	PMID:27141060	PMID:27332731	PMID:27365293	PMID:27369778	PMID:27956525
PMID:28012161	PMID:28430185	PMID:28468969	PMID:28709803	PMID:28813677	PMID:28848043	PMID:29023599	PMID:29050947	PMID:29120743	PMID:29120744	PMID:29453398	PMID:29571944
PMID:29651155	PMID:29915298	PMID:30010083	PMID:30364284	PMID:30703249	PMID:30791982	PMID:31088972	PMID:31132747	PMID:31284344	PMID:31405974	PMID:32076265	PMID:32251446
PMID:32601099	PMID:32673565	PMID:32753746	PMID:33547052	PMID:33798492	PMID:34075087	PMID:34274026	PMID:34504008	PMID:34587561	PMID:35144998	PMID:35298525	PMID:36002023
PMID:36982506	PMID:37285421	PMID:37463881	PMID:37483624	PMID:37923768	PMID:38531177	PMID:38905308

Genomics

Comparative Map Data

Il17f
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	20,847,370 - 20,855,498 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	20,847,370 - 20,860,841 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	20,777,146 - 20,785,274 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	20,777,146 - 20,790,617 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	20,767,227 - 20,774,351 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	20,762,918 - 20,764,663 (-)	NCBI		MGSCv36	mm8
Celera	1	20,651,214 - 20,658,338 (-)	NCBI		Celera
Cytogenetic Map	1	A4	NCBI
cM Map	1	6.49	NCBI

IL17F
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	52,236,681 - 52,245,689 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	52,236,681 - 52,245,689 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	52,101,479 - 52,109,298 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	52,209,443 - 52,217,257 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	52,209,442 - 52,217,257	NCBI
Celera	6	53,762,606 - 53,770,421 (-)	NCBI		Celera
Cytogenetic Map	6	p12.2	NCBI
HuRef	6	51,932,711 - 51,940,522 (-)	NCBI		HuRef
CHM1_1	6	52,103,743 - 52,111,557 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	52,075,437 - 52,084,442 (-)	NCBI		T2T-CHM13v2.0

Il17f
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	30,686,532 - 30,697,918 (-)	NCBI		GRCr8
mRatBN7.2	9	23,190,094 - 23,201,482 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	23,190,100 - 23,201,482 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	31,687,255 - 31,698,635 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	36,807,980 - 36,819,360 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	35,123,245 - 35,134,625 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	26,885,702 - 26,897,219 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	26,885,708 - 26,897,219 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	25,742,088 - 25,753,605 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	19,507,952 - 19,519,338 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	19,505,279 - 19,516,660 (-)	NCBI
Celera	9	20,765,976 - 20,777,363 (-)	NCBI		Celera
Cytogenetic Map	9	q13	NCBI

Il17f
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	5,852,767 - 5,859,208 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955411	5,852,767 - 5,859,208 (+)	NCBI	ChiLan1.0	ChiLan1.0

IL17F
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	66,704,846 - 66,713,100 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	62,581,667 - 62,589,927 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	51,789,210 - 51,797,470 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	53,057,313 - 53,065,124 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	53,057,318 - 53,065,124 (-)	Ensembl	panpan1.1		panPan2

IL17F
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	19,904,283 - 19,908,497 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	19,904,126 - 19,908,619 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	19,801,660 - 19,805,553 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	20,403,156 - 20,407,042 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	12	19,909,305 - 19,913,193 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	20,012,473 - 20,016,364 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	20,150,933 - 20,154,815 (-)	NCBI		UU_Cfam_GSD_1.0

Il17f
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	55,379,286 - 55,380,920 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	8,574,387 - 8,580,916 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	8,579,282 - 8,580,916 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IL17F
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	46,059,002 - 46,077,048 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	46,058,371 - 46,066,039 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	52,508,706 - 52,516,123 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IL17F
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	20,263,252 - 20,272,234 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	20,264,481 - 20,271,982 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	52,133,830 - 52,147,127 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Il17f
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624855	3,848,409 - 3,867,175 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624855	3,865,559 - 3,867,175 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Il17f
455 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	149
Count of miRNA genes:	136
Interacting mature miRNAs:	141
Transcripts:	ENSMUST00000039046
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
11039528	Ccc3_m	colitis susceptibility in the Collaborative Cross 3 (mouse)					1	3680142	195051546	Mouse
1301011	Cplaq4_m	circadian period of locomotor activity 4 (mouse)			Not determined		1	9673442	43673601	Mouse
1301073	Orch5_m	autoimmune orchitis resistance 5 (mouse)			Not determined		1	19065351	53065454	Mouse
1301275	Sle10_m	systematic lupus erythematosus susceptibility 10 (mouse)			Not determined		1	2882194	36882352	Mouse
15092046	Wngrme1_m	week nine growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
1301370	Adip1_m	adiposity 1 (mouse)			Not determined		1	2882194	36882352	Mouse
13824984	Twq5_m	testis weight QTL 5 (mouse)					1	3069992	184732197	Mouse
15092044	Wtgrme1_m	week ten growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
1301240	Sluc15_m	susceptibility to lung cancer 15 (mouse)			Not determined		1	19065351	53065454	Mouse
1301471	Obq2_m	obesity QTL 2 (mouse)			Not determined		1	3941620	37941887	Mouse
14700685	Civq2_m	cerebral infarct volume QTL 2 (mouse)					1	11340482	45340482	Mouse
1301756	Pgia1_m	proteoglycan induced arthritis 1 (mouse)			Not determined		1	19065351	53065454	Mouse
1301891	Alcp25_m	alcohol preference locus 25 (mouse)			Not determined		1	1	25203185	Mouse
1300834	Cia20_m	collagen induced arthritis 20 (mouse)			Not determined		1	1	25203185	Mouse
15092055	Lgrme1_m	late growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
4141646	Fecq3_m	fecundity QTL 3 (mouse)			Not determined		1	12916920	26517685	Mouse
12880407	V125Dq2_m	vitamin D active form serum level QTL 2 (mouse)					1	19339081	53339081	Mouse
15092050	Wsegrme1_m	week seven growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
15092051	Wegrme1_m	week eight growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
15092048	Wsigrme1_m	week six growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
1301482	Morph1_m	morphine antinociception 1 (mouse)			Not determined		1	1	30367747	Mouse
10043970	Obq23_m	obesity QTL 23 (mouse)			Not determined		1	5012665	39012665	Mouse
10412226	Alpq4_m	alcohol preference QTL 4 (mouse)			Not determined		1	1	22976684	Mouse

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_145856	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006495523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB116259	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC159614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF458064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK157101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY380822	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC145977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GM832044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000039046 ⟹ ENSMUSP00000046960

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	1	20,847,370 - 20,854,494 (-)	Ensembl
GRCm38.p6 Ensembl	1	20,777,146 - 20,784,270 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000189301 ⟹ ENSMUSP00000140122

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	1	20,848,007 - 20,860,841 (-)	Ensembl
GRCm38.p6 Ensembl	1	20,777,783 - 20,790,617 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000190692

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	1	20,857,703 - 20,860,809 (-)	Ensembl
GRCm38.p6 Ensembl	1	20,787,479 - 20,790,585 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000191111

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	1	20,847,903 - 20,849,778 (-)	Ensembl
GRCm38.p6 Ensembl	1	20,777,679 - 20,779,554 (-)	Ensembl

RefSeq Acc Id:

NM_145856 ⟹ NP_665855

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	1	20,847,370 - 20,854,494 (-)	NCBI
GRCm38	1	20,777,146 - 20,784,270 (-)	NCBI
MGSCv37	1	20,767,227 - 20,774,351 (-)	RGD
Celera	1	20,651,214 - 20,658,338 (-)	RGD
cM Map	1		ENTREZGENE

Sequence:

show sequence

GACATACCCAGGAAGACATACTTAGAAGAAAGTACTTCCTGAGGGAAGAAGCAGCCATTGGAGA
AACCAGCATGAAGTGCACCCGTGAAACAGCCATGGTCAAGTCTTTGCTACTGTTGATGTTGGGA
CTTGCCATTCTGAGGGAGGTAGCAGCTCGGAAGAACCCCAAAGCAGGGGTTCCTGCCTTGCAGA
AGGCTGGGAACTGTCCTCCCCTGGAGGATAACACTGTGAGAGTTGACATTCGAATCTTCAACCA
AAACCAGGGCATTTCTGTCCCACGTGAATTCCAGAACCGCTCCAGTTCCCCATGGGATTACAAC
ATCACTCGAGACCCCCACCGGTTCCCCTCAGAGATCGCTGAGGCCCAGTGCAGACACTCAGGCT
GCATCAATGCCCAGGGTCAGGAAGACAGCACCATGAACTCCGTCGCCATTCAGCAAGAAATCCT
GGTCCTTCGGAGGGAGCCCCAGGGCTGTTCTAATTCCTTCAGGTTGGAGAAGATGCTCCTAAAA
GTTGGCTGCACCTGTGTCAAGCCCATTGTCCACCAAGCGGCCTGACAACGCTGCATACAAAAAT
CAGTTGAAGACTTCCACTGAGAAAAAGCCTCCTTTTATCCAGAGCTCTGTGTGAAGCCCGATCT
CCAAGTCTTTATGCTTTCTAGGACTCTCAGTAAGGTGTGCATGGCATTCTTGCAGCTCTGCAGT
AGATATAGCTTGAACTTTCTGGCTTGCTTTAGAATTGTTACCAGTCCTGGTGTGTTCCCAATGC
CTCACTTAAACTCCTAAAAACAAAGGTAAATGAAGGCACCCTTGGCCCAGTCTCTTTGTGTTAG
ATGATGACCACAGTTCTTGTCTGTCAAGACTGTCACTTTGATGCAGTACCATTCTTGTAGAGTT
CAATGAAATGCTCATATTTGTGATGGAAAGAAAACAAACATAATCAGAATGCATGGGAGGAGGC
CTGTGTAGCAGGGGCTGGACTGGCAAGGAAGAAGCACACATGGTATGTGTGTTTTTAGAGAAAA
ATTTGGTAAATATAAATGAAGTTGGCATAAACTATTATATATTTATGTTGGTAGGGGAACTATA
CATATATTTATGACCTATTGATTATATATCAATTTAGTAGAAAATTAATATATCCATTAATTAT
ATAATAAAATATTTTTAATTCAAAAA

hide sequence

RefSeq Acc Id:

XM_006495523 ⟹ XP_006495586

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	1	20,847,383 - 20,855,498 (-)	NCBI
GRCm38	1	20,777,159 - 20,785,274 (-)	NCBI

Sequence:

show sequence

TAGCACAGCCAAGGCTACAGAAACCCTGTCTAGAAAAATTTTAAAAACGATAAGAAAACCAACA
AAAGTTTACTGTTATAGAATTGTATACACGAATATATAGTTTTGATCAAATTCTTACACTTGGG
GAAACTTCGTTTTGTAGATTGATACAAATTCACAATGGGACAATGTATAGAAGTTTTACCTGAT
CAAAATTGAGATTTTTTTAAGAAGTAAAGTACTGGTGTTTTTGAGGAACGGGGAATGAAATTAT
TTCCCTAGTATAAATGGGTGTGCTTAACAAATGCTTACTGCCTGGATCTAAACTGAGACAAATG
ATTTTGTTTTCTTTTTATTTTTCCTTTTGTTCCCTTTCTATATTTTTTTCAAGTCTACAAACTG
CACATGAACATTTCAATTTTCTATTTACTAATTCACTTTGGCTAACAAGAATGCTCCCAAATCA
GAGATAGCCAAGGAAATAGCCACTTATACCATGTGAATGGCACGATAGGGTCCTGTCATAGCGT
TAAAATAATTAGTCTAGAGAAACCACAAAAGACCCCGGGGATGTAATTTCTGAATTTCTCACTG
ATGTCACCCGTTTCTCTTATTTTATTTTCCCATCCACAGTGTTTAAAACCAAGTCTAGGCCAGG
ATGACTTACCCCCATTCACTGGATTCTACTGCATGACCCGAAAGCAGAACCCACACGCAGAGCA
TGACAAGAGTGTTGCTTTGTGGGGGAATTAAAGATCATGACAGTAATCTGTGACTCGGTTCATA
TCTGTAGTAAAGGAAGACATACTTAGAAGAAAGTACTTCCTGAGGGAAGAAGCAGCCATTGGAG
AAACCAGCATGAAGTGCACCCGTGAAACAGCCATGGTCAAGTCTTTGCTACTGTTGATGTTGGG
ACTTGCCATTCTGAGGGAGGTAGCAGCTCGGAAGAACCCCAAAGCAGGGGTTCCTGCCTTGCAG
AAGGCTGGGAACTGTCCTCCCCTGGAGGATAACACTGTGAGAGTTGACATTCGAATCTTCAACC
AAAACCAGGGCATTTCTGTCCCACGTGAATTCCAGAACCGCTCCAGTTCCCCATGGGATTACAA
CATCACTCGAGACCCCCACCGGTTCCCCTCAGAGATCGCTGAGGCCCAGTGCAGACACTCAGGC
TGCATCAATGCCCAGGGTCAGGAAGACAGCACCATGAACTCCGTCGCCATTCAGCAAGAAATCC
TGGTCCTTCGGAGGGAGCCCCAGGGCTGTTCTAATTCCTTCAGGTTGGAGAAGATGCTCCTAAA
AGTTGGCTGCACCTGTGTCAAGCCCATTGTCCACCAAGCGGCCTGACAACGCTGCATACAAAAA
TCAGTTGAAGACTTCCACTGAGAAAAAGCCTCCTTTTATCCAGAGCTCTGTGTGAAGCCCGATC
TCCAAGTCTTTATGCTTTCTAGGACTCTCAGTAAGGTGTGCATGGCATTCTTGCAGCTCTGCAG
TAGATATAGCTTGAACTTTCTGGCTTGCTTTAGAATTGTTACCAGTCCTGGTGTGTTCCCAATG
CCTCACTTAAACTCCTAAAAACAAAGGTAAATGAAGGCACCCTTGGCCCAGTCTCTTTGTGTTA
GATGATGACCACAGTTCTTGTCTGTCAAGACTGTCACTTTGATGCAGTACCATTCTTGTAGAGT
TCAATGAAATGCTCATATTTGTGATGGAAAGAAAACAAACATAATCAGAATGCATGGGAGGAGG
CCTGTGTAGCAGGGGCTGGACTGGCAAGGAAGAAGCACACATGGTATGTGTGTTTTTAGAGAAA
AATTTGGTAAATATAAATGAAGTTGGCATAAACTATTATATATTTATGTTGGTAGGGGAACTAT
ACATATATTTATGACCTATTGATTATATATCAATTTAGTAGAAAATTAATATATCCATTAATTA
TATAATAAAATATT

hide sequence

Protein Sequences


Protein RefSeqs	NP_665855	(Get FASTA)	NCBI Sequence Viewer
	XP_006495586	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAM77568	(Get FASTA)	NCBI Sequence Viewer
	AAQ88439	(Get FASTA)	NCBI Sequence Viewer
	BAC81535	(Get FASTA)	NCBI Sequence Viewer
	BAE33962	(Get FASTA)	NCBI Sequence Viewer
	CAV28592	(Get FASTA)	NCBI Sequence Viewer
	EDL14379	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000046960
	ENSMUSP00000046960.4
	ENSMUSP00000140122
	ENSMUSP00000140122.2
GenBank Protein	Q7TNI7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_665855 ⟸ NM_145856
- Peptide Label:	precursor
- UniProtKB:	Q8K4C3 (UniProtKB/Swiss-Prot), Q7TNI7 (UniProtKB/Swiss-Prot), A0A087WQB4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKCTRETAMVKSLLLLMLGLAILREVAARKNPKAGVPALQKAGNCPPLEDNTVRVDIRIFNQNQ GISVPREFQNRSSSPWDYNITRDPHRFPSEIAEAQCRHSGCINAQGQEDSTMNSVAIQQEILVL RREPQGCSNSFRLEKMLLKVGCTCVKPIVHQAA hide sequence

RefSeq Acc Id:	XP_006495586 ⟸ XM_006495523
- Peptide Label:	isoform X1
- UniProtKB:	Q8K4C3 (UniProtKB/Swiss-Prot), Q7TNI7 (UniProtKB/Swiss-Prot), A0A087WQB4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKCTRETAMVKSLLLLMLGLAILREVAARKNPKAGVPALQKAGNCPPLEDNTVRVDIRIFNQNQ GISVPREFQNRSSSPWDYNITRDPHRFPSEIAEAQCRHSGCINAQGQEDSTMNSVAIQQEILVL RREPQGCSNSFRLEKMLLKVGCTCVKPIVHQAA hide sequence

Ensembl Acc Id:

ENSMUSP00000046960 ⟸ ENSMUST00000039046

Ensembl Acc Id:

ENSMUSP00000140122 ⟸ ENSMUST00000189301

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q7TNI7-F1-model_v2	AlphaFold	Q7TNI7	1-161	view protein structure

Promoters

RGD ID:

6873268

Promoter ID:

EPDNEW_M85

Type:

single initiation site

Name:

Il17f_1

Description:

Mus musculus interleukin 17F , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	1	20,784,267 - 20,784,327	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2676631	AgrOrtholog
Ensembl Genes	ENSMUSG00000041872	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000039046	ENTREZGENE
	ENSMUST00000039046.10	UniProtKB/Swiss-Prot
	ENSMUST00000189301	ENTREZGENE
	ENSMUST00000189301.2	UniProtKB/TrEMBL
Gene3D-CATH	2.10.90.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Cystine-knot_cytokine	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL-17_chr	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL-17_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:257630	UniProtKB/Swiss-Prot
MGD	MGI:2676631	ENTREZGENE
NCBI Gene	257630	ENTREZGENE
Pfam	IL17	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Il17f	PhenoGen
PRINTS	INTRLEUKIN17	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF57501	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A087WQB4	ENTREZGENE, UniProtKB/TrEMBL
	IL17F_MOUSE	UniProtKB/Swiss-Prot
	Q3U093_MOUSE	UniProtKB/TrEMBL
	Q7TNI7	ENTREZGENE
	Q8K4C3	ENTREZGENE
UniProt Secondary	Q8K4C3	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-04-05	Il17f	interleukin 17F	C87042	expressed sequence C87042	Data merged from RGD:1610117	737654	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

Mammalian Phenotype

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

Mammalian Phenotype