Bcl11b (B cell leukemia/lymphoma 11B) - Rat Genome Database

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Gene: Bcl11b (B cell leukemia/lymphoma 11B) Mus musculus
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Symbol: Bcl11b
Name: B cell leukemia/lymphoma 11B
RGD ID: 1322423
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including T cell differentiation; epithelial cell development; and neuron differentiation. Located in neuron projection and nucleus. Part of SWI/SNF complex. Is expressed in several structures, including alimentary system; central nervous system; cranium; nose; and skin. Human ortholog(s) of this gene implicated in immunodeficiency 49. Orthologous to human BCL11B (BCL11 transcription factor B).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 9130430L19Rik; AI604821; B-cell CLL/lymphoma 11B; B-cell leukemia/lymphoma 11B; B-cell lymphoma/leukaemia 11B; B-cell lymphoma/leukemia 11B; B630002E05Rik; BCL-11B; COUP-TF interacting protein 2; COUP-TF-interacting protein 2; CTI; Ctip2; mRit1; radiation-induced tumor suppressor gene 1 protein; Ri; Rit1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912107,876,662 - 107,970,404 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12107,876,662 - 107,969,861 (-)EnsemblGRCm39 Ensembl
GRCm3812107,910,403 - 108,004,145 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12107,910,403 - 108,003,602 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712109,148,613 - 109,241,624 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612108,363,030 - 108,451,028 (-)NCBIMGSCv36mm8
Celera12109,151,974 - 109,245,238 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1259.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
neuron projection  (IDA)
nucleus  (IBA,IDA)
SWI/SNF complex  (IDA,ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal ameloblast differentiation  (IAGP)
abnormal ameloblast morphology  (IAGP)
abnormal bone structure  (IEA)
abnormal cell cycle  (IAGP)
abnormal corneocyte morphology  (IAGP)
abnormal enamel cord morphology  (IAGP)
abnormal enamel knot morphology  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal epidermis stratum corneum morphology  (IAGP)
abnormal epidermis stratum granulosum morphology  (IAGP)
abnormal eyelid fusion  (IEA)
abnormal facial morphology  (IEA)
abnormal incisor morphology  (IAGP)
abnormal leukocyte morphology  (IAGP)
abnormal NK cell differentiation  (IAGP)
abnormal odontoblast morphology  (IAGP)
abnormal outer dental epithelium morphology  (IAGP)
abnormal positive T cell selection  (IAGP)
abnormal stellate reticulum morphology  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal T cell differentiation  (IAGP)
abnormal T cell morphology  (IAGP)
abnormal T cell number  (IAGP)
abnormal T cell receptor beta chain V(D)J recombination  (IAGP)
abnormal thymocyte activation  (IAGP)
abnormal thymus cortex morphology  (IAGP)
abnormal thymus medulla morphology  (IAGP)
abnormal tooth development  (IAGP)
absent gastric milk in neonates  (IAGP)
absent T cells  (IAGP)
absent thymus corticomedullary boundary  (IAGP)
decreased birth body size  (IAGP)
decreased birth weight  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased double-negative T cell number  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased metastatic potential  (IAGP)
decreased thymocyte number  (IAGP)
enlarged mesenteric lymph nodes  (IAGP)
eyelids open at birth  (IAGP)
impaired skin barrier function  (IAGP)
increased B cell number  (IAGP)
increased bone mineral content  (IEA)
increased CD8-positive, alpha-beta T cell number  (IAGP)
increased dendritic cell number  (IAGP)
increased double-negative T cell number  (IAGP)
increased fasting circulating glucose level  (IEA)
increased gamma-delta T cell number  (IAGP)
increased lymphoma incidence  (IAGP)
increased NK cell number  (IAGP)
increased spleen weight  (IAGP)
increased thymocyte apoptosis  (IAGP)
increased vertical activity  (IEA)
lethality at weaning, complete penetrance  (IAGP)
long incisors  (IAGP)
midface hypoplasia  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
short basicranium  (IAGP)
short maxilla  (IAGP)
small incisors  (IAGP)
small molars  (IAGP)
spleen hyperplasia  (IAGP)
thin epidermis  (IAGP)
thymus hypoplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
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PMID:36996816   PMID:37054704   PMID:37071993   PMID:37074186   PMID:37085665   PMID:37115913   PMID:37125418   PMID:37139782   PMID:37171286   PMID:37171961   PMID:37172586   PMID:37237015  
PMID:37238632   PMID:37272771   PMID:37291945   PMID:37327344   PMID:37348506   PMID:37360696   PMID:37389991   PMID:37463454   PMID:37506696   PMID:37540708   PMID:37553426   PMID:37561632  
PMID:37584256   PMID:37590085   PMID:37610874   PMID:37612280   PMID:37665322   PMID:37738575   PMID:37758766   PMID:37838801   PMID:37900274   PMID:37906993   PMID:37995181   PMID:38019816  
PMID:38019906   PMID:38020907   PMID:38025769   PMID:38086370   PMID:38101002   PMID:38101413   PMID:38238293   PMID:38288355   PMID:38320000   PMID:38324473   PMID:38355793   PMID:38367882  
PMID:38383780   PMID:38402586   PMID:38429579   PMID:38488687   PMID:38489388   PMID:38512724   PMID:38574132   PMID:38636614   PMID:38697111   PMID:38713624   PMID:38760361   PMID:38816354  
PMID:38849354   PMID:38886378   PMID:39095712   PMID:39250533   PMID:39271675  


Genomics

Comparative Map Data
Bcl11b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912107,876,662 - 107,970,404 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12107,876,662 - 107,969,861 (-)EnsemblGRCm39 Ensembl
GRCm3812107,910,403 - 108,004,145 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12107,910,403 - 108,003,602 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712109,148,613 - 109,241,624 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612108,363,030 - 108,451,028 (-)NCBIMGSCv36mm8
Celera12109,151,974 - 109,245,238 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1259.1NCBI
BCL11B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381499,169,287 - 99,272,197 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1499,169,287 - 99,272,197 (-)EnsemblGRCh38hg38GRCh38
GRCh371499,635,624 - 99,738,534 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361498,705,377 - 98,807,575 (-)NCBINCBI36Build 36hg18NCBI36
Build 341498,705,376 - 98,807,575NCBI
Celera1479,691,368 - 79,793,512 (-)NCBICelera
Cytogenetic Map14q32.2NCBI
HuRef1479,819,226 - 79,921,464 (-)NCBIHuRef
CHM1_11499,573,389 - 99,675,578 (-)NCBICHM1_1
T2T-CHM13v2.01493,400,844 - 93,503,767 (-)NCBIT2T-CHM13v2.0
Bcl11b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86132,598,968 - 132,692,123 (-)NCBIGRCr8
mRatBN7.26126,834,531 - 126,927,720 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6126,834,531 - 126,928,224 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6126,958,692 - 127,050,867 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06127,253,714 - 127,345,900 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06126,612,161 - 126,704,296 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06131,834,097 - 131,927,251 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6131,834,097 - 131,926,272 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06141,004,477 - 141,097,643 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46132,292,671 - 132,384,572 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16132,296,789 - 132,389,378 (-)NCBI
Celera6124,393,881 - 124,486,186 (-)NCBICelera
Cytogenetic Map6q32NCBI
Bcl11b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543820,564,449 - 20,637,103 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543820,562,345 - 20,637,662 (-)NCBIChiLan1.0ChiLan1.0
BCL11B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215100,325,797 - 100,429,008 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11499,542,293 - 99,645,444 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01479,795,262 - 79,898,472 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11499,122,231 - 99,205,962 (-)NCBIpanpan1.1PanPan1.1panPan2
BCL11B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1867,622,592 - 67,713,922 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl867,622,708 - 67,714,404 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha867,145,953 - 67,237,226 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0867,909,299 - 68,000,574 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl867,909,387 - 68,001,543 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1867,570,743 - 67,661,895 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0867,636,646 - 67,728,187 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0868,033,837 - 68,125,174 (-)NCBIUU_Cfam_GSD_1.0
Bcl11b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086406,972,307 - 7,063,288 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366043,023,844 - 3,110,083 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366043,023,781 - 3,110,104 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCL11B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7120,205,008 - 120,295,936 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17120,205,008 - 120,295,737 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27127,759,537 - 127,855,267 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BCL11B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12477,122,591 - 77,222,562 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2477,122,689 - 77,221,454 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605364,224,342 - 64,347,710 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bcl11b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247344,560,699 - 4,647,858 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247344,560,362 - 4,649,219 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bcl11b
3162 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1802
Count of miRNA genes:750
Interacting mature miRNAs:962
Transcripts:ENSMUST00000066060, ENSMUST00000109887, ENSMUST00000109891
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300883Ath21_matherosclerosis 21 (mouse)Not determined1285961579119961683Mouse
39128213Lwq23_mliver weight QTL 10 (mouse)1280956708113383533Mouse
12910532Nrq10a_mnoise-induced hearing loss resistant QTL 10a (mouse)1292750025120092757Mouse
12910533Nrq10_mnoise-induced hearing loss resistant QTL 10 (mouse)1292750025120092757Mouse
1357463Vtbt14_mvertebral trabecular bone trait 14 (mouse)Not determined1292936097120092757Mouse
12910790Pwgrq7_mpre-weaning growth rate QTL 7 (mouse)1290937367108645308Mouse
1301269Sluc12_msusceptibility to lung cancer 12 (mouse)Not determined1296860337120092757Mouse
4142007Chlq17_mcirculating hormone level QTL 17 (mouse)Not determined1288052874120092757Mouse
25823169Hrsq8_mhost response to SARS QTL 8, log titer (mouse)1281696245108495368Mouse
4142002Tbqt3_mtibia bone quality traits 3 (mouse)Not determined1235285496109936243Mouse
11039526Ccc1_mcolitis susceptibility in the Collaborative Cross 1 (mouse)1293528334111028223Mouse
1300545Lifespan3_mlife span 3 (mouse)Not determined1288052874120092757Mouse
4141610Tailaq1_mtail length adjusted QTL 1 (mouse)Not determined80956708113383533Mouse
1301836Heal5_mwound healing/regeneration 5 (mouse)Not determined1289939031120092757Mouse
13524846Ppiq11_mprepulse inhibition QTL 11 (mouse)1282666396116666396Mouse
10412156Nociq3_mnociceptive sensitivity inflammatory QTL 3 (mouse)Not determined1286396075114831653Mouse
1301879Insq10_minsulin QTL 10 (mouse)Not determined1283532075117532224Mouse
13524842Ppiq10a_mprepulse inhibition QTL 10a (mouse)1277512220111512220Mouse
10402491Dipa4_mdrug induced psychomotor activation 4 (mouse)Not determined1291222515120092757Mouse
1301492Dbsty3_mdiabesity 3 (mouse)Not determined1283532075117532224Mouse
4141335W6q10_mweight 6 weeks QTL 10 (mouse)Not determined80956708113383533Mouse
1302138Im6_mimmunoregulatory 6 (mouse)Not determined1296860337120092757Mouse
5491194Mobq3_mmultigenic obesity QTL 3 (mouse)Not determined1289664071120092757Mouse
1301689Skull18_mskull morphology 18 (mouse)Not determined1273887422107887526Mouse
1301308Prdt4_mprion disease incubation time 4 (mouse)Not determined1288308354120092757Mouse
1301922Bbaa6_mB.burgdorferi-associated arthritis 6 (mouse)Not determined1290308268120092757Mouse
1302177Dps2_mdelta power in slow-wave sleep 2 (mouse)Not determined1294146064120092757Mouse
1301926Adip6_madiposity 6 (mouse)Not determined1273887422107887526Mouse
10412075Nils1_mneointima lesion size 1 (mouse)Not determined12102024665120092757Mouse
27226793Feml10_mfemur length 10, 5 week (mouse)1268346774113363620Mouse
1300973Abmm_mantibody mediated myocarditis (mouse)Not determined1293264461120092757Mouse
4142401Egq10_mearly growth QTL 10 (mouse)Not determined80956708113383533Mouse
13524849Ppiq11a_mprepulse inhibition QTL 11a (mouse)1280989143114989143Mouse

Markers in Region
AI604821  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,910,647 - 107,910,753UniSTSGRCm38
MGSCv3712109,148,857 - 109,148,963UniSTSGRCm37
Celera12109,152,218 - 109,152,324UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.0UniSTS
Whitehead/MRC_RH121011.83UniSTS
Bcl11b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,915,469 - 107,915,868UniSTSGRCm38
MGSCv3712109,153,679 - 109,154,078UniSTSGRCm37
Celera12109,157,046 - 109,157,445UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.0UniSTS
cM Map12 UniSTS
REN47699  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,913,789 - 107,914,022UniSTSGRCm38
MGSCv3712109,151,999 - 109,152,232UniSTSGRCm37
Celera12109,155,364 - 109,155,597UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.0UniSTS
REN47704  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,914,895 - 107,915,176UniSTSGRCm38
MGSCv3712109,153,105 - 109,153,386UniSTSGRCm37
Celera12109,156,471 - 109,156,752UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.0UniSTS
REN47709  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,916,496 - 107,916,752UniSTSGRCm38
MGSCv3712109,154,706 - 109,154,962UniSTSGRCm37
Celera12109,158,073 - 109,158,329UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.0UniSTS
REN47882  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,952,266 - 107,952,506UniSTSGRCm38
MGSCv3712109,190,476 - 109,190,716UniSTSGRCm37
Celera12109,193,965 - 109,194,205UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.0UniSTS
REN47927  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,960,077 - 107,960,360UniSTSGRCm38
MGSCv3712109,198,287 - 109,198,570UniSTSGRCm37
Celera12109,201,942 - 109,202,223UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.0UniSTS
REN47976  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,970,678 - 107,970,957UniSTSGRCm38
MGSCv3712109,208,888 - 109,209,167UniSTSGRCm37
Celera12109,212,535 - 109,212,814UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.0UniSTS
REN48002  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,976,111 - 107,976,367UniSTSGRCm38
MGSCv3712109,214,321 - 109,214,577UniSTSGRCm37
Celera12109,217,963 - 109,218,219UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.0UniSTS
ECD13810  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,937,868 - 107,938,366UniSTSGRCm38
MGSCv3712109,176,078 - 109,176,576UniSTSGRCm37
Celera12109,179,484 - 109,179,982UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.0UniSTS
ECD17061  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,916,617 - 107,917,028UniSTSGRCm38
MGSCv3712109,154,827 - 109,155,238UniSTSGRCm37
Celera12109,158,194 - 109,158,605UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.0UniSTS
stSG632080  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,913,856 - 107,915,262UniSTSGRCm38
MGSCv3712109,152,066 - 109,153,472UniSTSGRCm37
Celera12109,155,431 - 109,156,839UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.0UniSTS
stSG632129  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,965,708 - 107,966,711UniSTSGRCm38
MGSCv3712109,203,918 - 109,204,921UniSTSGRCm37
Celera12109,207,566 - 109,208,569UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.0UniSTS
B2N(I)  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,986,574 - 107,986,781UniSTSGRCm38
MGSCv3712109,224,784 - 109,224,991UniSTSGRCm37
Celera12109,228,451 - 109,228,658UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.48UniSTS
MCA1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,923,581 - 107,923,795UniSTSGRCm38
MGSCv3712109,161,791 - 109,162,005UniSTSGRCm37
Celera12109,165,142 - 109,165,378UniSTS
Cytogenetic Map12F1UniSTS
cM Map1252.36UniSTS
Bcl11b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812107,915,452 - 107,915,676UniSTSGRCm38
MGSCv3712109,153,662 - 109,153,886UniSTSGRCm37
Celera12109,157,029 - 109,157,253UniSTS
Cytogenetic Map12F1UniSTS
cM Map12 UniSTS
Bcl11b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12F1UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001079883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006516110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006516111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006516113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006516114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006516115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006516116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011244152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011244153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB043551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB043553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB043583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC119219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC119921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF186019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK020296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM950501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ442983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ745012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV563304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000066060   ⟹   ENSMUSP00000068258
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12107,876,662 - 107,969,861 (-)Ensembl
GRCm38.p6 Ensembl12107,910,403 - 108,003,602 (-)Ensembl
Ensembl Acc Id: ENSMUST00000109887   ⟹   ENSMUSP00000105513
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12107,881,481 - 107,969,673 (-)Ensembl
GRCm38.p6 Ensembl12107,915,222 - 108,003,414 (-)Ensembl
Ensembl Acc Id: ENSMUST00000109891   ⟹   ENSMUSP00000105517
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12107,881,481 - 107,969,673 (-)Ensembl
GRCm38.p6 Ensembl12107,915,222 - 108,003,414 (-)Ensembl
RefSeq Acc Id: NM_001079883   ⟹   NP_001073352
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,969,673 (-)NCBI
GRCm3812107,910,403 - 108,003,414 (-)NCBI
MGSCv3712109,148,613 - 109,241,624 (-)RGD
Celera12109,151,974 - 109,245,238 (-)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001286343   ⟹   NP_001273272
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,969,673 (-)NCBI
GRCm3812107,910,403 - 108,003,414 (-)NCBI
Celera12109,151,974 - 109,245,238 (-)NCBI
Sequence:
RefSeq Acc Id: NM_021399   ⟹   NP_067374
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,969,673 (-)NCBI
GRCm3812107,910,403 - 108,003,414 (-)NCBI
MGSCv3712109,148,613 - 109,241,624 (-)RGD
Celera12109,151,974 - 109,245,238 (-)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006516110   ⟹   XP_006516173
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,959,269 (-)NCBI
GRCm3812107,910,403 - 107,993,009 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006516111   ⟹   XP_006516174
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,970,404 (-)NCBI
GRCm3812107,910,403 - 108,004,145 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006516113   ⟹   XP_006516176
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,959,244 (-)NCBI
GRCm3812107,910,403 - 107,992,984 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006516114   ⟹   XP_006516177
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,970,392 (-)NCBI
GRCm3812107,910,403 - 108,004,133 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006516115   ⟹   XP_006516178
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,899,098 (-)NCBI
GRCm3812107,910,403 - 107,931,283 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006516116   ⟹   XP_006516179
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,947,376 (-)NCBI
GRCm3812107,910,403 - 107,981,118 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011244152   ⟹   XP_011242454
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,959,269 (-)NCBI
GRCm3812107,910,403 - 107,993,009 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011244153   ⟹   XP_011242455
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,970,395 (-)NCBI
GRCm3812107,910,403 - 108,004,136 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315143   ⟹   XP_017170632
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,968,264 (-)NCBI
GRCm3812107,910,403 - 108,001,784 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315144   ⟹   XP_017170633
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,968,264 (-)NCBI
GRCm3812107,910,403 - 108,001,832 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315145   ⟹   XP_017170634
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,968,264 (-)NCBI
GRCm3812107,910,403 - 108,001,937 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036157546   ⟹   XP_036013439
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,970,395 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036157547   ⟹   XP_036013440
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,957,830 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036157548   ⟹   XP_036013441
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,968,264 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036157549   ⟹   XP_036013442
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912107,876,662 - 107,957,830 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001073352 (Get FASTA)   NCBI Sequence Viewer  
  NP_001273272 (Get FASTA)   NCBI Sequence Viewer  
  NP_067374 (Get FASTA)   NCBI Sequence Viewer  
  XP_006516173 (Get FASTA)   NCBI Sequence Viewer  
  XP_006516174 (Get FASTA)   NCBI Sequence Viewer  
  XP_006516176 (Get FASTA)   NCBI Sequence Viewer  
  XP_006516177 (Get FASTA)   NCBI Sequence Viewer  
  XP_006516178 (Get FASTA)   NCBI Sequence Viewer  
  XP_006516179 (Get FASTA)   NCBI Sequence Viewer  
  XP_011242454 (Get FASTA)   NCBI Sequence Viewer  
  XP_011242455 (Get FASTA)   NCBI Sequence Viewer  
  XP_017170632 (Get FASTA)   NCBI Sequence Viewer  
  XP_017170633 (Get FASTA)   NCBI Sequence Viewer  
  XP_017170634 (Get FASTA)   NCBI Sequence Viewer  
  XP_036013439 (Get FASTA)   NCBI Sequence Viewer  
  XP_036013440 (Get FASTA)   NCBI Sequence Viewer  
  XP_036013441 (Get FASTA)   NCBI Sequence Viewer  
  XP_036013442 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF63683 (Get FASTA)   NCBI Sequence Viewer  
  AAH19503 (Get FASTA)   NCBI Sequence Viewer  
  BAB32728 (Get FASTA)   NCBI Sequence Viewer  
  BAB32729 (Get FASTA)   NCBI Sequence Viewer  
  BAB32730 (Get FASTA)   NCBI Sequence Viewer  
  BAC40438 (Get FASTA)   NCBI Sequence Viewer  
  BAE41279 (Get FASTA)   NCBI Sequence Viewer  
  EDL18728 (Get FASTA)   NCBI Sequence Viewer  
  EDL18729 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000068258
  ENSMUSP00000068258.5
  ENSMUSP00000105513
  ENSMUSP00000105513.2
  ENSMUSP00000105517
  ENSMUSP00000105517.3
GenBank Protein Q99PV8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_067374   ⟸   NM_021399
- Peptide Label: isoform b
- UniProtKB: Q99PV8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001073352   ⟸   NM_001079883
- Peptide Label: isoform a
- UniProtKB: Q99PV7 (UniProtKB/Swiss-Prot),   Q99PV6 (UniProtKB/Swiss-Prot),   Q8C2I1 (UniProtKB/Swiss-Prot),   Q9JLF8 (UniProtKB/Swiss-Prot),   Q99PV8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001273272   ⟸   NM_001286343
- Peptide Label: isoform c
- UniProtKB: A0A0R4J1E1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006516174   ⟸   XM_006516111
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006516177   ⟸   XM_006516114
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_006516173   ⟸   XM_006516110
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006516176   ⟸   XM_006516113
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_006516179   ⟸   XM_006516116
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_006516178   ⟸   XM_006516115
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_011242455   ⟸   XM_011244153
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011242454   ⟸   XM_011244152
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017170634   ⟸   XM_017315145
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_017170633   ⟸   XM_017315144
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_017170632   ⟸   XM_017315143
- Peptide Label: isoform X7
- Sequence:
Ensembl Acc Id: ENSMUSP00000068258   ⟸   ENSMUST00000066060
Ensembl Acc Id: ENSMUSP00000105513   ⟸   ENSMUST00000109887
Ensembl Acc Id: ENSMUSP00000105517   ⟸   ENSMUST00000109891
RefSeq Acc Id: XP_036013439   ⟸   XM_036157546
- Peptide Label: isoform X5
RefSeq Acc Id: XP_036013441   ⟸   XM_036157548
- Peptide Label: isoform X8
RefSeq Acc Id: XP_036013442   ⟸   XM_036157549
- Peptide Label: isoform X8
RefSeq Acc Id: XP_036013440   ⟸   XM_036157547
- Peptide Label: isoform X7
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99PV8-F1-model_v2 AlphaFold Q99PV8 1-884 view protein structure

Promoters
RGD ID:6822772
Promoter ID:MM_KWN:12673
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   Brain
Transcripts:ENSMUST00000066047,   ENSMUST00000109887,   NM_021399,   OTTMUST00000046516
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3612109,241,989 - 109,242,489 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1929913 AgrOrtholog
Ensembl Genes ENSMUSG00000048251 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000066060 ENTREZGENE
  ENSMUST00000066060.11 UniProtKB/Swiss-Prot
  ENSMUST00000109887 ENTREZGENE
  ENSMUST00000109887.8 UniProtKB/TrEMBL
  ENSMUST00000109891 ENTREZGENE
  ENSMUST00000109891.3 UniProtKB/Swiss-Prot
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Dev/Hematopoietic_TF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:58208 UniProtKB/Swiss-Prot
MGD MGI:1929913 ENTREZGENE
NCBI Gene 58208 ENTREZGENE
PANTHER B-CELL LYMPHOMA/LEUKEMIA 11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B-CELL LYMPHOMA/LEUKEMIA 11B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bcl11b PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J1E1 ENTREZGENE, UniProtKB/TrEMBL
  BC11B_MOUSE UniProtKB/Swiss-Prot
  Q3TEG9_MOUSE UniProtKB/TrEMBL
  Q8C2I1 ENTREZGENE
  Q99PV6 ENTREZGENE
  Q99PV7 ENTREZGENE
  Q99PV8 ENTREZGENE
  Q9JLF8 ENTREZGENE
UniProt Secondary Q8C2I1 UniProtKB/Swiss-Prot
  Q99PV6 UniProtKB/Swiss-Prot
  Q99PV7 UniProtKB/Swiss-Prot
  Q9JLF8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-02-07 Bcl11b  B cell leukemia/lymphoma 11B  Bcl11b  B-cell leukemia/lymphoma 11B  Symbol and/or name change 5135510 APPROVED