Ctps1 (cytidine 5'-triphosphate synthase 1) - Rat Genome Database

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Gene: Ctps1 (cytidine 5'-triphosphate synthase 1) Mus musculus
Analyze
Symbol: Ctps1
Name: cytidine 5'-triphosphate synthase 1
RGD ID: 1322316
MGI Page MGI
Description: Enables protein asparagine deamidase activity. Involved in negative regulation of type I interferon production. Predicted to be located in cytosol. Predicted to be active in several cellular components, including chromatin; cytoophidium; and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and respiratory system. Human ortholog(s) of this gene implicated in immunodeficiency 24. Orthologous to human CTPS1 (CTP synthase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CTP synthase 1; CTP synthetase 1; Ctps; UTP--ammonia ligase 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm16465  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394120,397,065 - 120,427,473 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4120,397,065 - 120,427,473 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384120,539,868 - 120,570,276 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4120,539,868 - 120,570,276 (-)Ensemblmm10GRCm38
MGSCv374120,212,473 - 120,242,881 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364120,037,501 - 120,067,899 (-)NCBIMGSCv36mm8
Celera4119,256,495 - 119,286,990 (-)NCBICelera
Cytogenetic Map4D2.1NCBI
cM Map456.52NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2-butoxyethanol  (EXP)
2-palmitoylglycerol  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
aconitine  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
beauvericin  (ISO)
belinostat  (ISO)
benzalkonium chloride  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
choline  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dichloroacetic acid  (EXP)
diclofenac  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (EXP,ISO)
enniatin  (ISO)
enzyme inhibitor  (ISO)
erianin  (EXP)
fenpyroximate  (ISO)
flutamide  (ISO)
folic acid  (EXP)
FR900359  (ISO)
furan  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
glutathione  (ISO)
GSK-J4  (ISO)
indole-3-methanol  (ISO)
indometacin  (ISO)
inulin  (EXP)
ivermectin  (ISO)
L-methionine  (EXP)
lead diacetate  (EXP)
lipopolysaccharide  (ISO)
menadione  (ISO)
methimazole  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
orphenadrine  (ISO)
ozone  (EXP,ISO)
paracetamol  (ISO)
paraquat  (ISO)
pentachlorophenol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
phosgene  (EXP)
pirinixic acid  (EXP)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propanal  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sulfadimethoxine  (ISO)
tamoxifen  (EXP)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
theophylline  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
tremolite asbestos  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
Triptolide  (EXP)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA,ISO,ISS)
cytoophidium  (IBA,IEA,ISO)
cytoplasm  (IBA,IEA,ISO)
cytosol  (IEA)
nucleus  (IEA,ISO,ISS)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal intestinal epithelium morphology  (IAGP)
abnormal skin morphology  (IEA)
abnormal small intestinal villus morphology  (IAGP)
abnormal small intestine crypts of Lieberkuhn morphology  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal thymus physiology  (IAGP)
anemia  (IAGP)
decreased B cell number  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased effector memory T-helper cell number  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased germinal center B cell number  (IAGP)
decreased hematopoietic stem cell number  (IAGP)
decreased hemoglobin content  (IAGP)
decreased IgM level  (IAGP)
decreased inflammatory response  (IAGP)
decreased lymphocyte cell number  (IAGP)
decreased megakaryocyte-erythroid progenitor cell number  (IAGP)
decreased NK cell number  (IAGP)
decreased regulatory T cell number  (IAGP)
decreased small intestinal villus height  (IAGP)
decreased T cell number  (IAGP)
decreased T cell proliferation  (IAGP)
decreased T follicular helper cell number  (IAGP)
embryonic growth arrest  (IAGP)
embryonic lethality prior to organogenesis  (IEA)
embryonic lethality prior to organogenesis, complete penetrance  (IAGP)
enlarged lymph nodes  (IEA)
enlarged spleen  (IAGP)
enlarged urinary bladder  (IEA)
impaired humoral immune response  (IAGP)
increased CD4-positive, alpha-beta T cell number  (IAGP)
increased CD8-positive, alpha-beta T cell number  (IAGP)
increased CD8-positive, naive alpha-beta T cell number  (IAGP)
no abnormal phenotype detected  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
reticulocytopenia  (IAGP)
small thymus  (IAGP)
thymus hypoplasia  (IAGP)
weight loss  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Identification of novel cellular targets in biliary tract cancers using global gene expression technology. Hansel DE, etal., Am J Pathol. 2003 Jul;163(1):217-29.
2. De novo synthesis of pyrimidine nucleotides; emerging interfaces with signal transduction pathways. Huang M and Graves LM, Cell Mol Life Sci. 2003 Feb;60(2):321-36.
3. Alteration of gene expression during nasopharyngeal carcinogenesis revealed by oligonucleotide microarray after microdissection of tumor tissue and normal epithelia from nasopharynx. Liu ZQ, etal., Chin Med J (Engl). 2009 Feb 20;122(4):437-43.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:14681479   PMID:15489334  
PMID:16141072   PMID:16141073   PMID:16602821   PMID:17967808   PMID:18307411   PMID:18799693   PMID:21677750   PMID:21873635   PMID:22730407   PMID:22922362   PMID:24008161   PMID:24457600  
PMID:26365490   PMID:26370502   PMID:28378742   PMID:30457570   PMID:30550785   PMID:32325033   PMID:32560809   PMID:34022203   PMID:36114006   PMID:37442135   PMID:38355793   PMID:38438357  
PMID:39719712  


Genomics

Comparative Map Data
Ctps1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394120,397,065 - 120,427,473 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4120,397,065 - 120,427,473 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384120,539,868 - 120,570,276 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4120,539,868 - 120,570,276 (-)Ensemblmm10GRCm38
MGSCv374120,212,473 - 120,242,881 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364120,037,501 - 120,067,899 (-)NCBIMGSCv36mm8
Celera4119,256,495 - 119,286,990 (-)NCBICelera
Cytogenetic Map4D2.1NCBI
cM Map456.52NCBI
CTPS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38140,979,696 - 41,012,565 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl140,979,300 - 41,012,565 (+)Ensemblhg38GRCh38
GRCh37141,445,368 - 41,478,237 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36141,217,594 - 41,250,822 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34141,114,535 - 41,147,321NCBI
Celera139,727,935 - 39,761,156 (+)NCBICelera
Cytogenetic Map1p34.2NCBI
HuRef139,562,096 - 39,595,318 (+)NCBIHuRef
CHM1_1141,560,914 - 41,594,145 (+)NCBICHM1_1
T2T-CHM13v2.0140,849,069 - 40,881,929 (+)NCBIT2T-CHM13v2.0
Ctps1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85139,372,349 - 139,440,441 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5139,410,249 - 139,440,465 (-)EnsemblGRCr8
mRatBN7.25134,125,022 - 134,154,155 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5134,125,025 - 134,154,180 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5136,853,019 - 136,882,151 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05138,609,477 - 138,638,609 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05138,630,096 - 138,659,228 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05139,475,934 - 139,505,065 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5139,475,934 - 139,505,065 (-)Ensemblrn6Rnor6.0
Rnor_5.05143,259,189 - 143,288,320 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45141,136,686 - 141,165,817 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5132,680,893 - 132,710,010 (-)NCBICelera
RGSC_v3.15141,141,913 - 141,189,364 (-)NCBI
Cytogenetic Map5q36NCBI
Ctps1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955537774,002 - 813,254 (+)Ensembl
ChiLan1.0NW_004955537773,664 - 811,084 (+)NCBIChiLan1.0ChiLan1.0
CTPS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21185,803,413 - 185,836,251 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11184,945,025 - 184,978,125 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0140,275,581 - 40,308,421 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1141,592,069 - 41,624,455 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl141,592,509 - 41,624,455 (+)EnsemblpanPan2panpan1.1
CTPS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1152,067,767 - 2,093,014 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl152,067,763 - 2,093,014 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha152,326,992 - 2,356,330 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0152,158,160 - 2,187,539 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl152,158,162 - 2,187,530 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1152,063,812 - 2,093,145 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0152,123,983 - 2,153,311 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0152,139,372 - 2,168,710 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ctps1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505856,777,925 - 56,808,428 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647422,602,800 - 22,633,169 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647422,611,037 - 22,633,208 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTPS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6170,201,751 - 170,233,016 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16170,201,749 - 170,233,105 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26157,249,352 - 157,280,709 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CTPS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12091,905,452 - 91,938,188 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2091,901,771 - 91,937,819 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603324,943,247 - 24,976,031 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctps1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624892376,800 - 421,850 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ctps1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1136,418,001 - 36,447,006 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ctps1
1389 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:652
Count of miRNA genes:400
Interacting mature miRNAs:453
Transcripts:ENSMUST00000030381, ENSMUST00000140891, ENSMUST00000147980
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123127211Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
12904002Opfaq9_mopen field activity QTL 9 (mouse)492975790126975790Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
14696689Gdq2_mgrooming duration QTL 2, females (mouse)4100857197124893793Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1300918Stheal4_msoft tissue heal 4 (mouse)Not determined489969627123969747Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
4141330Iva1_misovaleric acid smelling 1 (mouse)Not determined117071971120723203Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
10412072Ssen1_msuseptibility to Sendai virus 1 (mouse)Not determined4109658132133154782Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
13208565Bmiq6_mbody mass index QTL 6 (mouse)4110857197125893793Mouse
1300655Nidds_mnon-insulin-dependent diabetes mellitus in SJL (mouse)Not determined4115030777129465915Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
1300689Dob1_mDietary obesity 1 (mouse)Body weight4101574601123127211Mouse
1301847Fecq2_mfecundity QTL 2 (mouse)Not determined4100071971134072206Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
1301597Anxty_manxiety (mouse)Not determined474137574128009280Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
1301106Skts7_mskin tumor susceptibility 7 (mouse)Not determined4100071971134072206Mouse
1301233Sbw2_msplenomegaly-NZB x NZW 2 (mouse)Not determined494957579128009280Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
27095924Pglq2_mpelvic girdle length QTL 2, 5 week (mouse)469118237130727311Mouse
15039368Nmrs19_mNAFLD-associated magnetic resonance shift 19 (mouse)490882780124882780Mouse
27095917Scvln14_msacral vertebrae length 2, 16 week (mouse)468018237130277062Mouse
1301731Cafq2_mcaffeine metabolism QTL 2 (mouse)Not determined494732255128732454Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124055180Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
12880433Fgf23lq1_mFGF23 serum level QTL 1 (mouse)4101157197135157197Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
1300580Lbw2_mlupus NZB x NZW 2 (mouse)Not determined498545539128009280Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000128993793Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse
12903992Opfaq6_mopen field activity QTL 6 (mouse)4119064995121366497Mouse
11553870Cmmm_mcarcinoma modifier of MSM (mouse)490590668124590781Mouse
1301996Mmtg2_mmodifier of mammary tumor growth 2 (mouse)Not determined4116270979124055180Mouse

Markers in Region
Ctps  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D2.2UniSTS
cM Map457.0UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000030381   ⟹   ENSMUSP00000030381
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4120,397,065 - 120,427,473 (-)Ensembl
GRCm38.p6 Ensembl4120,539,868 - 120,570,276 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140891
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4120,399,166 - 120,405,298 (-)Ensembl
GRCm38.p6 Ensembl4120,541,969 - 120,548,101 (-)Ensembl
Ensembl Acc Id: ENSMUST00000147980
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4120,399,108 - 120,402,264 (-)Ensembl
GRCm38.p6 Ensembl4120,541,911 - 120,545,067 (-)Ensembl
RefSeq Acc Id: NM_001355491   ⟹   NP_001342420
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394120,397,065 - 120,426,656 (-)NCBI
GRCm384120,539,868 - 120,569,459 (-)NCBI
Sequence:
RefSeq Acc Id: NM_016748   ⟹   NP_058028
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394120,397,065 - 120,427,473 (-)NCBI
GRCm384120,539,868 - 120,570,276 (-)NCBI
MGSCv374120,212,473 - 120,242,881 (-)RGD
Celera4119,256,495 - 119,286,990 (-)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_058028   ⟸   NM_016748
- UniProtKB: Q922Y4 (UniProtKB/Swiss-Prot),   P70698 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001342420   ⟸   NM_001355491
- UniProtKB: P70698 (UniProtKB/Swiss-Prot),   Q922Y4 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSMUSP00000030381   ⟸   ENSMUST00000030381
Protein Domains
CTP synthase N-terminal   Glutamine amidotransferase type-1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70698-F1-model_v2 AlphaFold P70698 1-591 view protein structure

Promoters
RGD ID:6835099
Promoter ID:MM_KWN:39403
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B4,   MEF_B6
Transcripts:UC008UNI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364120,240,426 - 120,240,977 (-)MPROMDB
RGD ID:6835097
Promoter ID:MM_KWN:39404
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:UC008UNJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364120,242,446 - 120,243,077 (-)MPROMDB
RGD ID:6884486
Promoter ID:EPDNEW_M5694
Type:initiation region
Name:Ctps_1
Description:Mus musculus cytidine 5'-triphosphate synthase , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384120,570,224 - 120,570,284EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1858304 AgrOrtholog
Ensembl Genes ENSMUSG00000028633 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000030381 ENTREZGENE
  ENSMUST00000030381.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
  3.40.50.880 UniProtKB/Swiss-Prot
InterPro Class_I_gatase-like UniProtKB/Swiss-Prot
  CTP_synthase UniProtKB/Swiss-Prot
  CTP_synthase_N UniProtKB/Swiss-Prot
  GATASE UniProtKB/Swiss-Prot
  GATase1_CTP_Synthase UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report mmu:51797 UniProtKB/Swiss-Prot
MGD MGI:1858304 ENTREZGENE
NCBI Gene 51797 ENTREZGENE
PANTHER CTP SYNTHASE 1 UniProtKB/Swiss-Prot
  PTHR11550 UniProtKB/Swiss-Prot
Pfam CTP_synth_N UniProtKB/Swiss-Prot
  GATase UniProtKB/Swiss-Prot
PhenoGen Ctps1 PhenoGen
PROSITE GATASE_TYPE_1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52317 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
UniProt P70698 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3TPP2_MOUSE UniProtKB/TrEMBL
  Q922Y4 ENTREZGENE
UniProt Secondary Q922Y4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-05 Ctps1  cytidine 5'-triphosphate synthase 1  Ctps  cytidine 5'-triphosphate synthase  Symbol and/or name updated 27372883 PROVISIONAL