Mecom (MDS1 and EVI1 complex locus) - Rat Genome Database

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Gene: Mecom (MDS1 and EVI1 complex locus) Mus musculus
Analyze
Symbol: Mecom
Name: MDS1 and EVI1 complex locus
RGD ID: 1322217
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and histone H3K9 methyltransferase activity. Involved in hematopoietic stem cell proliferation; heterochromatin organization; and negative regulation of DNA-templated transcription. Acts upstream of or within several processes, including embryonic limb morphogenesis; positive regulation of brown fat cell differentiation; and ureter morphogenesis. Located in nucleus. Is expressed in several structures, including brain; embryo mesenchyme; genitourinary system; respiratory system; and sensory organ. Used to study otitis media. Human ortholog(s) of this gene implicated in myeloid neoplasm. Orthologous to human MECOM (MDS1 and EVI1 complex locus).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D630039M04Rik; ecotropic viral integration site 1; ecotropic virus integration site 1 protein; Ev; Evi; Evi-1; Evi1; histone-lysine N-methyltransferase MECOM; Jb; Jbo; Mds; Mds1; MDS1 and EVI1 complex locus protein EVI1; MDS1 and EVI1 complex locus protein MDS1; MDS1-E; Mds1-Evi1; MGC183337; MGC184568; myelodysplasia syndrome 1 homolog; myelodysplasia syndrome 1 homolog (human); myelodysplasia syndrome 1 protein homolog; Prd; Prdm3; ZNFPR; Znfpr1b1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39330,005,445 - 30,563,937 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl330,005,445 - 30,602,157 (-)EnsemblGRCm39 Ensembl
GRCm38329,951,296 - 30,509,759 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl329,951,296 - 30,548,008 (-)EnsemblGRCm38mm10GRCm38
MGSCv37329,850,218 - 30,408,409 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36330,143,789 - 30,188,737 (-)NCBIMGSCv36mm8
Celera329,872,412 - 30,423,227 (-)NCBICelera
Cytogenetic Map3A3NCBI
cM Map312.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1,4-benzoquinone  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2-palmitoylglycerol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
acetaldehyde  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (EXP)
carmustine  (ISO)
casticin  (EXP)
chlordecone  (EXP)
chlorpyrifos  (EXP)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
diclofenac  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
flusilazole  (EXP,ISO)
formaldehyde  (ISO)
gentamycin  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
hydroxyurea  (ISO)
iron dichloride  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
pirinixic acid  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
Soman  (ISO)
succimer  (EXP)
temozolomide  (ISO)
testosterone  (ISO)
tetraphene  (EXP)
thapsigargin  (ISO)
theophylline  (ISO)
thimerosal  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal amnion morphology  (IAGP)
abnormal bone collagen fibril morphology  (IAGP)
abnormal bone marrow cell morphology/development  (IAGP)
abnormal common myeloid progenitor cell morphology  (IAGP)
abnormal cranial ganglia morphology  (IAGP)
abnormal craniofacial morphology  (IEA)
abnormal diencephalon morphology  (IAGP)
abnormal fetal liver hematopoietic progenitor cell morphology  (IAGP)
abnormal forebrain morphology  (IAGP)
abnormal heart looping  (IAGP)
abnormal heart morphology  (IAGP)
abnormal hematopoietic stem cell morphology  (IAGP)
abnormal hematopoietic stem cell physiology  (IAGP)
abnormal immune system organ morphology  (IAGP)
abnormal interscapular fat pad morphology  (IAGP)
abnormal intervertebral disk morphology  (IAGP)
abnormal ligament morphology  (IAGP)
abnormal limb development  (IAGP)
abnormal limb posture  (IAGP)
abnormal liver bud morphology  (IAGP)
abnormal lumbar vertebrae morphology  (IAGP)
abnormal mesonephros morphology  (IAGP)
abnormal myotome development  (IAGP)
abnormal neutrophil differentiation  (IAGP)
abnormal pharyngeal arch morphology  (IAGP)
abnormal pinna reflex  (IAGP)
abnormal platelet morphology  (IAGP)
abnormal sacrum morphology  (IAGP)
abnormal spinal nerve morphology  (IAGP)
abnormal spine curvature  (IAGP)
abnormal superior glossopharyngeal ganglion morphology  (IAGP)
abnormal superior vagus ganglion morphology  (IAGP)
abnormal tail position or orientation  (IAGP)
abnormal tendon collagen fibril morphology  (IAGP)
abnormal tympanic membrane morphology  (IAGP)
abnormal vertebral articular process morphology  (IAGP)
abnormal vertebral transverse process morphology  (IAGP)
abnormal vitelline vasculature morphology  (IAGP)
absent hindlimb buds  (IAGP)
absent myotome  (IAGP)
absent nucleus pulposus  (IAGP)
absent paraxial mesoderm  (IAGP)
absent sclerotome  (IAGP)
brachydactyly  (IAGP)
caudal vertebral fusion  (IAGP)
deafness  (IAGP)
decreased B cell number  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral density  (IAGP)
decreased bone strength  (IAGP)
decreased bone trabecula number  (IAGP)
decreased common myeloid progenitor cell number  (IAGP)
decreased embryo size  (IAGP)
decreased hematopoietic precursor cell number  (IAGP)
decreased hematopoietic stem cell number  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased trabecular bone connectivity density  (IAGP)
decreased trabecular bone thickness  (IAGP)
decreased trabecular bone volume  (IAGP)
delayed endochondral bone ossification  (IAGP)
distended pericardium  (IAGP)
double outlet right ventricle  (IAGP)
edema  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
enlarged pericardium  (IAGP)
exostosis  (IAGP)
hemorrhage  (IAGP)
impaired hearing  (IAGP)
incomplete somite formation  (IAGP)
increased bone trabecular spacing  (IAGP)
increased brown fat cell lipid droplet size  (IAGP)
increased leukocyte cell number  (IAGP)
increased miscarriage rate  (IAGP)
increased susceptibility to otitis media  (IAGP)
increased susceptibility to xenobiotic induced morbidity/mortality  (IAGP)
interrupted aortic arch  (IAGP)
intervertebral disk degeneration  (IAGP)
kyphoscoliosis  (IAGP)
kyphosis  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
lethality, complete penetrance  (IAGP)
lordokyphosis  (IAGP)
lordosis  (IAGP)
lumbar vertebral fusion  (IAGP)
malocclusion  (IAGP)
middle ear effusion  (IAGP)
middle ear polyps  (IAGP)
no abnormal phenotype detected  (IAGP)
overriding aortic valve  (IAGP)
pale placenta  (IAGP)
pale yolk sac  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
persistent truncus arteriosus  (IAGP)
pharyngeal arch hypoplasia  (IAGP)
polydactyly  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
pulmonary vascular congestion  (IAGP)
reduced female fertility  (IAGP)
reduced fertility  (IAGP)
reduced male fertility  (IAGP)
respiratory system inflammation  (IAGP)
sacral vertebral fusion  (IAGP)
skin edema  (IAGP)
slow postnatal weight gain  (IAGP)
small embryonic telencephalon  (IAGP)
small forelimb buds  (IAGP)
small trigeminal ganglion  (IAGP)
thrombocytopenia  (IAGP)
trabecula carnea hypoplasia  (IAGP)
tympanic membrane perforation  (IAGP)
ventricular septal defect  (IAGP)
vertebral fusion  (IAGP)
weakness  (IAGP)
weight loss  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse. Hood D, etal., Dis Model Mech. 2016 Jan 1;9(1):69-79. doi: 10.1242/dmm.021659. Epub 2015 Nov 26.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Fusion of ETV6 to MDS1/EVI1 as a result of t(3;12)(q26;p13) in myeloproliferative disorders. Peeters P, etal., Cancer Res. 1997 Feb 15;57(4):564-9.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1370341   PMID:1374101   PMID:1535334   PMID:1542575   PMID:1676977   PMID:1765007   PMID:1797234   PMID:1893871   PMID:2105003   PMID:2106070   PMID:2113669   PMID:2115646  
PMID:2542863   PMID:2565740   PMID:2574151   PMID:2676841   PMID:2827004   PMID:2842066   PMID:2897103   PMID:2902233   PMID:6255464   PMID:7749229   PMID:7929053   PMID:7949740  
PMID:8108138   PMID:8183551   PMID:8188294   PMID:8288240   PMID:8390965   PMID:8557637   PMID:8563752   PMID:8661061   PMID:8824796   PMID:9256345   PMID:9307024   PMID:9434954  
PMID:9786996   PMID:9837768   PMID:10349636   PMID:10641791   PMID:10867128   PMID:10903917   PMID:11042159   PMID:11069022   PMID:11076861   PMID:11217851   PMID:11328817   PMID:11568182  
PMID:12477932   PMID:14555651   PMID:14681479   PMID:14996723   PMID:15618518   PMID:15849193   PMID:15889140   PMID:16006653   PMID:16109773   PMID:16141072   PMID:16141073   PMID:16602821  
PMID:16761014   PMID:16979153   PMID:17014970   PMID:17029558   PMID:17339028   PMID:17507183   PMID:17635584   PMID:17913523   PMID:18287559   PMID:18303859   PMID:18496560   PMID:18500823  
PMID:18619962   PMID:18682242   PMID:19767769   PMID:20015077   PMID:20057387   PMID:20448201   PMID:20647008   PMID:20980401   PMID:21190993   PMID:21267068   PMID:21289308   PMID:21397932  
PMID:21666053   PMID:21695170   PMID:21731775   PMID:21873635   PMID:22028672   PMID:22084405   PMID:22161860   PMID:22308434   PMID:22421546   PMID:22473998   PMID:22474389   PMID:22553314  
PMID:22558218   PMID:22560297   PMID:22581859   PMID:22939622   PMID:23547050   PMID:23776681   PMID:23920117   PMID:24021671   PMID:24316420   PMID:24550112   PMID:24586749   PMID:24703692  
PMID:24747972   PMID:24903482   PMID:25298035   PMID:25773539   PMID:25843711   PMID:25907616   PMID:26234679   PMID:26525672   PMID:26967394   PMID:27129260   PMID:27378689   PMID:27568519  
PMID:27748374   PMID:28391050   PMID:28630119   PMID:29379870   PMID:29449589   PMID:29688375   PMID:30315161   PMID:30898767   PMID:31076455   PMID:31822659   PMID:32025033   PMID:32044379  
PMID:32169905   PMID:32179733   PMID:32325033   PMID:32330245   PMID:32437910   PMID:33003409   PMID:33762742   PMID:34363719   PMID:34407416   PMID:34709266   PMID:34995520   PMID:35107126  
PMID:35132438   PMID:35177643   PMID:35364055   PMID:35709354   PMID:36104564   PMID:36246635   PMID:36269819   PMID:36384171   PMID:36596814   PMID:36906847   PMID:37099686   PMID:37524711  
PMID:38355793  


Genomics

Comparative Map Data
Mecom
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39330,005,445 - 30,563,937 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl330,005,445 - 30,602,157 (-)EnsemblGRCm39 Ensembl
GRCm38329,951,296 - 30,509,759 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl329,951,296 - 30,548,008 (-)EnsemblGRCm38mm10GRCm38
MGSCv37329,850,218 - 30,408,409 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36330,143,789 - 30,188,737 (-)NCBIMGSCv36mm8
Celera329,872,412 - 30,423,227 (-)NCBICelera
Cytogenetic Map3A3NCBI
cM Map312.66NCBI
MECOM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383169,083,507 - 169,663,712 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3169,083,499 - 169,663,775 (-)EnsemblGRCh38hg38GRCh38
GRCh373168,801,295 - 169,381,500 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363170,283,981 - 170,348,216 (-)NCBINCBI36Build 36hg18NCBI36
Build 343170,285,251 - 170,346,795NCBI
Celera3167,199,811 - 167,780,346 (-)NCBICelera
Cytogenetic Map3q26.2NCBI
HuRef3166,172,067 - 166,751,440 (-)NCBIHuRef
CHM1_13168,763,814 - 169,344,623 (-)NCBICHM1_1
T2T-CHM13v2.03171,867,472 - 172,447,663 (-)NCBIT2T-CHM13v2.0
Mecom
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82114,837,815 - 115,393,052 (+)NCBIGRCr8
mRatBN7.22112,909,353 - 113,464,583 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2112,909,321 - 113,464,590 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2119,556,006 - 120,111,375 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02117,668,580 - 118,223,966 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02112,665,046 - 112,939,546 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02117,396,084 - 117,993,604 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2117,396,007 - 117,454,769 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02137,080,581 - 137,665,758 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42114,814,409 - 114,882,676 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12114,759,366 - 114,831,177 (-)NCBI
Celera2108,052,044 - 108,638,470 (+)NCBICelera
Cytogenetic Map2q24NCBI
Mecom
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544818,259,083 - 18,439,646 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544818,259,847 - 18,542,085 (-)NCBIChiLan1.0ChiLan1.0
MECOM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22166,979,626 - 167,557,973 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13166,984,499 - 167,562,688 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03166,099,530 - 166,677,739 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13174,154,814 - 174,731,344 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3174,154,814 - 174,731,252 (-)Ensemblpanpan1.1panPan2
MECOM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13433,747,495 - 34,299,389 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3433,748,843 - 34,299,276 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3442,824,121 - 43,375,991 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03433,824,972 - 34,377,968 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3433,826,305 - 34,377,648 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13433,772,569 - 34,324,831 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03433,739,669 - 34,292,140 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03434,003,272 - 34,556,327 (-)NCBIUU_Cfam_GSD_1.0
Mecom
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602100,339,369 - 100,879,677 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365933,106,202 - 3,282,596 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365932,742,236 - 3,282,596 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MECOM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13107,754,482 - 108,335,702 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113107,753,207 - 108,336,136 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213116,467,012 - 117,101,295 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MECOM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11519,726,423 - 20,320,832 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1520,256,384 - 20,320,834 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606328,540,228 - 29,135,736 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mecom
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473047,104,319 - 47,284,839 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473047,104,929 - 47,693,885 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mecom
18048 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5214
Count of miRNA genes:928
Interacting mature miRNAs:1316
Transcripts:ENSMUST00000061088, ENSMUST00000108270, ENSMUST00000108271, ENSMUST00000166001, ENSMUST00000170212, ENSMUST00000172694, ENSMUST00000172697, ENSMUST00000172754, ENSMUST00000173022, ENSMUST00000173059, ENSMUST00000173411, ENSMUST00000173495, ENSMUST00000173899, ENSMUST00000174406, ENSMUST00000174413, ENSMUST00000174428
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1024922183184946Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1024922183184946Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31024922183184946Mouse
1301114Ssial2_msusceptibility to sialadenitis 2 (mouse)Not determined32017486254180103Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
12904010Cfq8_mconditioned fear QTL 8 (mouse)32476823231332103Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
4142092Tgq13_mtriglyceride QTL 13 (mouse)Not determined1828816852288168Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31024922183184946Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1024922183184946Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3758617468716946Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31024922183184946Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1300559Thypr3_mthymocyte proliferative response 3 (mouse)Not determined3452541938525519Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1301358Eae20_mexperimental allergic encephalomyelitis 20 (mouse)Not determined31163045345630591Mouse

Markers in Region
AI503489  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38330,350,317 - 30,350,407UniSTSGRCm38
MGSCv37330,249,239 - 30,249,329UniSTSGRCm37
Celera330,262,356 - 30,262,446UniSTS
Cytogenetic Map3A3UniSTS
cM Map314.4UniSTS
Whitehead/MRC_RH3331.33UniSTS
D3Mit178  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38330,393,206 - 30,393,398UniSTSGRCm38
MGSCv37330,292,128 - 30,292,320UniSTSGRCm37
Celera330,305,207 - 30,305,399UniSTS
Cytogenetic Map3A3UniSTS
cM Map313.8UniSTS
Whitehead Genetic312.0UniSTS
Whitehead/MRC_RH3329.39UniSTS
D3Mit271  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38330,225,831 - 30,225,935UniSTSGRCm38
MGSCv37330,124,753 - 30,124,857UniSTSGRCm37
Celera330,138,820 - 30,138,928UniSTS
Cytogenetic Map3A3UniSTS
cM Map313.8UniSTS
Whitehead Genetic312.0UniSTS
D3Mit46  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38330,013,439 - 30,013,604UniSTSGRCm38
MGSCv37329,912,361 - 29,912,526UniSTSGRCm37
Celera329,934,453 - 29,934,612UniSTS
Cytogenetic Map3A3UniSTS
cM Map313.8UniSTS
Whitehead Genetic312.0UniSTS
D3Mit46.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38330,013,610 - 30,013,725UniSTSGRCm38
MGSCv37329,912,532 - 29,912,647UniSTSGRCm37
Celera329,934,618 - 29,934,733UniSTS
Cytogenetic Map3A3UniSTS
cM Map313.8UniSTS
cM Map3 UniSTS
Whitehead_YAC3 UniSTS
AU019034  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38330,350,140 - 30,350,375UniSTSGRCm38
MGSCv37330,249,062 - 30,249,297UniSTSGRCm37
Celera330,262,181 - 30,262,414UniSTS
Cytogenetic Map3A3UniSTS
cM Map314.4UniSTS
Whitehead/MRC_RH3331.28UniSTS
Evi1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3A3UniSTS
cM Map314.4UniSTS
cM Map314.4UniSTS
cM Map314.4UniSTS
UniSTS:234651  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38330,350,138 - 30,350,344UniSTSGRCm38
MGSCv37330,249,060 - 30,249,266UniSTSGRCm37
Celera330,262,179 - 30,262,383UniSTS
Cytogenetic Map3A3UniSTS
cM Map314.4UniSTS
AJ010015  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3A3UniSTS
cM Map314.4UniSTS
Whitehead/MRC_RH3331.28UniSTS
D3Mit46.3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38330,013,333 - 30,013,475UniSTSGRCm38
MGSCv37329,912,255 - 29,912,397UniSTSGRCm37
Celera329,934,347 - 29,934,489UniSTS
Cytogenetic Map3A3UniSTS
cM Map313.8UniSTS
cM Map3 UniSTS
Evi1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3A3UniSTS
cM Map314.4UniSTS
Evi1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3A3UniSTS
cM Map314.4UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001361034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001370768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001370769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011249656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011249659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011249660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011249661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011249662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011249663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011249664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017319454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC119995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI551247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ001482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ010015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ010016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL683891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL691419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL772145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL929377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC076620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC139762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ665270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M21829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M64494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000061088   ⟹   ENSMUSP00000051057
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,292,121 - 30,292,468 (-)Ensembl
GRCm38.p6 Ensembl330,237,972 - 30,238,319 (-)Ensembl
Ensembl Acc Id: ENSMUST00000108270   ⟹   ENSMUSP00000103905
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,005,455 - 30,067,654 (-)Ensembl
GRCm38.p6 Ensembl329,951,306 - 30,013,505 (-)Ensembl
Ensembl Acc Id: ENSMUST00000108271   ⟹   ENSMUSP00000103906
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,005,456 - 30,194,572 (-)Ensembl
GRCm38.p6 Ensembl329,951,307 - 30,140,423 (-)Ensembl
Ensembl Acc Id: ENSMUST00000166001   ⟹   ENSMUSP00000128563
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,006,931 - 30,051,851 (-)Ensembl
GRCm38.p6 Ensembl329,952,782 - 29,997,702 (-)Ensembl
Ensembl Acc Id: ENSMUST00000170212
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,038,110 - 30,067,210 (-)Ensembl
GRCm38.p6 Ensembl329,983,961 - 30,013,061 (-)Ensembl
Ensembl Acc Id: ENSMUST00000172694   ⟹   ENSMUSP00000134303
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,005,445 - 30,067,305 (-)Ensembl
GRCm38.p6 Ensembl329,951,296 - 30,013,156 (-)Ensembl
Ensembl Acc Id: ENSMUST00000172697   ⟹   ENSMUSP00000134117
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,019,605 - 30,563,971 (-)Ensembl
GRCm38.p6 Ensembl329,965,456 - 30,509,822 (-)Ensembl
Ensembl Acc Id: ENSMUST00000172754   ⟹   ENSMUSP00000134152
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,031,493 - 30,602,157 (-)Ensembl
GRCm38.p6 Ensembl329,977,344 - 30,548,008 (-)Ensembl
Ensembl Acc Id: ENSMUST00000173022
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,290,718 - 30,563,636 (-)Ensembl
GRCm38.p6 Ensembl330,236,569 - 30,509,487 (-)Ensembl
Ensembl Acc Id: ENSMUST00000173059   ⟹   ENSMUSP00000133310
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,006,716 - 30,292,311 (-)Ensembl
GRCm38.p6 Ensembl329,952,567 - 30,238,162 (-)Ensembl
Ensembl Acc Id: ENSMUST00000173411
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,069,123 - 30,563,882 (-)Ensembl
GRCm38.p6 Ensembl330,014,974 - 30,509,733 (-)Ensembl
Ensembl Acc Id: ENSMUST00000173495   ⟹   ENSMUSP00000134626
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,005,448 - 30,563,882 (-)Ensembl
GRCm38.p6 Ensembl329,951,299 - 30,509,733 (-)Ensembl
Ensembl Acc Id: ENSMUST00000173899   ⟹   ENSMUSP00000133410
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,017,223 - 30,563,663 (-)Ensembl
GRCm38.p6 Ensembl329,963,074 - 30,509,514 (-)Ensembl
Ensembl Acc Id: ENSMUST00000174406   ⟹   ENSMUSP00000133942
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,051,878 - 30,065,588 (-)Ensembl
GRCm38.p6 Ensembl329,997,729 - 30,011,439 (-)Ensembl
Ensembl Acc Id: ENSMUST00000174413   ⟹   ENSMUSP00000134278
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,006,865 - 30,051,812 (-)Ensembl
GRCm38.p6 Ensembl329,952,716 - 29,997,663 (-)Ensembl
Ensembl Acc Id: ENSMUST00000174428
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,038,110 - 30,067,353 (-)Ensembl
GRCm38.p6 Ensembl329,983,961 - 30,013,204 (-)Ensembl
Ensembl Acc Id: ENSMUST00000195690
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl330,289,592 - 30,292,109 (-)Ensembl
GRCm38.p6 Ensembl330,235,443 - 30,237,960 (-)Ensembl
RefSeq Acc Id: NM_001361034   ⟹   NP_001347963
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,563,908 (-)NCBI
GRCm38329,951,296 - 30,509,759 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001370768   ⟹   NP_001357697
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,563,908 (-)NCBI
GRCm38329,951,296 - 30,509,759 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001370769   ⟹   NP_001357698
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,563,908 (-)NCBI
GRCm38329,951,296 - 30,509,759 (-)NCBI
Sequence:
RefSeq Acc Id: NM_007963   ⟹   NP_031989
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,067,353 (-)NCBI
GRCm38329,951,296 - 30,013,204 (-)NCBI
MGSCv37329,850,218 - 30,408,409 (-)RGD
Celera329,872,412 - 30,423,227 (-)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_021442   ⟹   NP_067417
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,290,718 - 30,563,824 (-)NCBI
GRCm38330,236,569 - 30,509,675 (-)NCBI
MGSCv37329,850,218 - 30,408,409 (-)RGD
Celera329,872,412 - 30,423,227 (-)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006535393   ⟹   XP_006535456
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,067,651 (-)NCBI
GRCm38329,951,296 - 30,013,505 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006535394   ⟹   XP_006535457
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,067,651 (-)NCBI
GRCm38329,951,296 - 30,013,505 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011249656   ⟹   XP_011247958
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,292,470 (-)NCBI
GRCm38329,951,296 - 30,238,321 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011249659   ⟹   XP_011247961
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,292,470 (-)NCBI
GRCm38329,951,296 - 30,238,321 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011249660   ⟹   XP_011247962
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,292,470 (-)NCBI
GRCm38329,951,296 - 30,238,321 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011249661   ⟹   XP_011247963
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,103,274 (-)NCBI
GRCm38329,951,296 - 30,049,133 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011249662   ⟹   XP_011247964
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,292,470 (-)NCBI
GRCm38329,951,296 - 30,238,321 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011249663   ⟹   XP_011247965
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,292,470 (-)NCBI
GRCm38329,951,296 - 30,238,321 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011249664   ⟹   XP_011247966
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,316,999 (-)NCBI
GRCm38329,951,296 - 30,262,858 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017319454   ⟹   XP_017174943
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,033,746 - 30,317,021 (-)NCBI
GRCm38329,979,597 - 30,262,951 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030252416   ⟹   XP_030108276
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,067,652 (-)NCBI
GRCm38329,951,296 - 30,013,504 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162888   ⟹   XP_036018781
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,563,937 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162889   ⟹   XP_036018782
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,067,651 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162890   ⟹   XP_036018783
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,067,651 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162891   ⟹   XP_036018784
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,067,671 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162892   ⟹   XP_036018785
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39330,005,445 - 30,067,652 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001347963 (Get FASTA)   NCBI Sequence Viewer  
  NP_001357697 (Get FASTA)   NCBI Sequence Viewer  
  NP_001357698 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415374 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415375 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415376 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415377 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415378 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415379 (Get FASTA)   NCBI Sequence Viewer  
  NP_031989 (Get FASTA)   NCBI Sequence Viewer  
  NP_067417 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535456 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535457 (Get FASTA)   NCBI Sequence Viewer  
  XP_011247958 (Get FASTA)   NCBI Sequence Viewer  
  XP_011247961 (Get FASTA)   NCBI Sequence Viewer  
  XP_011247962 (Get FASTA)   NCBI Sequence Viewer  
  XP_011247963 (Get FASTA)   NCBI Sequence Viewer  
  XP_011247964 (Get FASTA)   NCBI Sequence Viewer  
  XP_011247965 (Get FASTA)   NCBI Sequence Viewer  
  XP_011247966 (Get FASTA)   NCBI Sequence Viewer  
  XP_017174943 (Get FASTA)   NCBI Sequence Viewer  
  XP_030108276 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018781 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018782 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018783 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018784 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018785 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40581 (Get FASTA)   NCBI Sequence Viewer  
  AAI39763 (Get FASTA)   NCBI Sequence Viewer  
  AFG17061 (Get FASTA)   NCBI Sequence Viewer  
  BAC28336 (Get FASTA)   NCBI Sequence Viewer  
  BAC34525 (Get FASTA)   NCBI Sequence Viewer  
  CAA04777 (Get FASTA)   NCBI Sequence Viewer  
  CAA08971 (Get FASTA)   NCBI Sequence Viewer  
  EDL34954 (Get FASTA)   NCBI Sequence Viewer  
  EDL34955 (Get FASTA)   NCBI Sequence Viewer  
  EDL34956 (Get FASTA)   NCBI Sequence Viewer  
  EDL34957 (Get FASTA)   NCBI Sequence Viewer  
  EDL34958 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000051057.7
  ENSMUSP00000103905
  ENSMUSP00000103905.4
  ENSMUSP00000103906.4
  ENSMUSP00000128563
  ENSMUSP00000128563.2
  ENSMUSP00000133310
  ENSMUSP00000133310.2
  ENSMUSP00000133410
  ENSMUSP00000133410.2
  ENSMUSP00000133942.2
  ENSMUSP00000134117.2
  ENSMUSP00000134152.2
  ENSMUSP00000134278.2
  ENSMUSP00000134303
  ENSMUSP00000134303.2
  ENSMUSP00000134626
  ENSMUSP00000134626.2
GenBank Protein P14404 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_067417   ⟸   NM_021442
- Peptide Label: isoform 2
- UniProtKB: F6SZX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_031989   ⟸   NM_007963
- Peptide Label: isoform 1
- UniProtKB: G3UZ13 (UniProtKB/TrEMBL),   Q8CCA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006535457   ⟸   XM_006535394
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006535456   ⟸   XM_006535393
- Peptide Label: isoform X5
- UniProtKB: O35700 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247965   ⟸   XM_011249663
- Peptide Label: isoform X13
- UniProtKB: G3UWJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247958   ⟸   XM_011249656
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011247964   ⟸   XM_011249662
- Peptide Label: isoform X12
- UniProtKB: G3UWJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247963   ⟸   XM_011249661
- Peptide Label: isoform X7
- UniProtKB: O35700 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247966   ⟸   XM_011249664
- Peptide Label: isoform X15
- UniProtKB: G3UWJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247962   ⟸   XM_011249660
- Peptide Label: isoform X3
- UniProtKB: O35700 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247961   ⟸   XM_011249659
- Peptide Label: isoform X2
- UniProtKB: O35700 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017174943   ⟸   XM_017319454
- Peptide Label: isoform X14
- UniProtKB: G3UYK2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001357698   ⟸   NM_001370769
- Peptide Label: isoform 5
- UniProtKB: P14404 (UniProtKB/Swiss-Prot),   G3UWT0 (UniProtKB/Swiss-Prot),   Q9Z1L8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001357697   ⟸   NM_001370768
- Peptide Label: isoform 4
RefSeq Acc Id: NP_001347963   ⟸   NM_001361034
- Peptide Label: isoform 3
RefSeq Acc Id: XP_030108276   ⟸   XM_030252416
- Peptide Label: isoform X8
Ensembl Acc Id: ENSMUSP00000103905   ⟸   ENSMUST00000108270
Ensembl Acc Id: ENSMUSP00000103906   ⟸   ENSMUST00000108271
Ensembl Acc Id: ENSMUSP00000134152   ⟸   ENSMUST00000172754
Ensembl Acc Id: ENSMUSP00000134303   ⟸   ENSMUST00000172694
Ensembl Acc Id: ENSMUSP00000134117   ⟸   ENSMUST00000172697
Ensembl Acc Id: ENSMUSP00000128563   ⟸   ENSMUST00000166001
Ensembl Acc Id: ENSMUSP00000134278   ⟸   ENSMUST00000174413
Ensembl Acc Id: ENSMUSP00000133942   ⟸   ENSMUST00000174406
Ensembl Acc Id: ENSMUSP00000134626   ⟸   ENSMUST00000173495
Ensembl Acc Id: ENSMUSP00000133310   ⟸   ENSMUST00000173059
Ensembl Acc Id: ENSMUSP00000051057   ⟸   ENSMUST00000061088
Ensembl Acc Id: ENSMUSP00000133410   ⟸   ENSMUST00000173899
RefSeq Acc Id: XP_036018781   ⟸   XM_036162888
- Peptide Label: isoform X4
RefSeq Acc Id: XP_036018784   ⟸   XM_036162891
- Peptide Label: isoform X10
RefSeq Acc Id: XP_036018785   ⟸   XM_036162892
- Peptide Label: isoform X11
RefSeq Acc Id: XP_036018783   ⟸   XM_036162890
- Peptide Label: isoform X9
RefSeq Acc Id: XP_036018782   ⟸   XM_036162889
- Peptide Label: isoform X6
- UniProtKB: O35700 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type   SET

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P14404-F1-model_v2 AlphaFold P14404 1-1232 view protein structure

Promoters
RGD ID:6833768
Promoter ID:MM_KWN:33951
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:UC008OUM.1,   UC008OUN.1,   UC008OUO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36329,896,816 - 29,897,316 (-)MPROMDB
RGD ID:6880396
Promoter ID:EPDNEW_M3649
Type:multiple initiation site
Name:Mecom_2
Description:Mus musculus MDS1 and EVI1 complex locus , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3650  EPDNEW_M3651  EPDNEW_M3652  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38330,013,142 - 30,013,202EPDNEW
RGD ID:6880398
Promoter ID:EPDNEW_M3650
Type:multiple initiation site
Name:Mecom_3
Description:Mus musculus MDS1 and EVI1 complex locus , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3649  EPDNEW_M3651  EPDNEW_M3652  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38330,140,423 - 30,140,483EPDNEW
RGD ID:6880400
Promoter ID:EPDNEW_M3651
Type:single initiation site
Name:Mecom_1
Description:Mus musculus MDS1 and EVI1 complex locus , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3649  EPDNEW_M3650  EPDNEW_M3652  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38330,491,538 - 30,491,598EPDNEW
RGD ID:6880402
Promoter ID:EPDNEW_M3652
Type:multiple initiation site
Name:Mecom_4
Description:Mus musculus MDS1 and EVI1 complex locus , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3649  EPDNEW_M3650  EPDNEW_M3651  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38330,509,497 - 30,509,557EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95457 AgrOrtholog
Ensembl Genes ENSMUSG00000027684 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSMUSG00000051636
Ensembl Transcript ENSMUST00000061088.7 UniProtKB/TrEMBL
  ENSMUST00000108270 ENTREZGENE
  ENSMUST00000108270.10 UniProtKB/Swiss-Prot
  ENSMUST00000108271.10 UniProtKB/TrEMBL
  ENSMUST00000166001 ENTREZGENE
  ENSMUST00000166001.8 UniProtKB/TrEMBL
  ENSMUST00000172694 ENTREZGENE
  ENSMUST00000172694.8 UniProtKB/TrEMBL
  ENSMUST00000172697.8 UniProtKB/TrEMBL
  ENSMUST00000172754.8 UniProtKB/TrEMBL
  ENSMUST00000173022 ENTREZGENE
  ENSMUST00000173059 ENTREZGENE
  ENSMUST00000173059.8 UniProtKB/TrEMBL
  ENSMUST00000173495 ENTREZGENE
  ENSMUST00000173495.8 UniProtKB/TrEMBL
  ENSMUST00000173899 ENTREZGENE
  ENSMUST00000173899.8 UniProtKB/TrEMBL
  ENSMUST00000174406.2 UniProtKB/TrEMBL
  ENSMUST00000174413.8 UniProtKB/TrEMBL
Gene3D-CATH 2.170.270.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C2H2-ZF_domain UniProtKB/TrEMBL
  SET_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zinc_finger UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14013 UniProtKB/Swiss-Prot
MGD MGI:95457 ENTREZGENE
NCBI Gene 14013 ENTREZGENE
PANTHER DEFORMED WINGS-RELATED UniProtKB/TrEMBL
  FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE MECOM UniProtKB/TrEMBL
  IP01201P-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LOW QUALITY PROTEIN: MDS1 AND EVI1 COMPLEX LOCUS PROTEIN EVI1-RELATED UniProtKB/TrEMBL
  PR DOMAIN ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 711 UniProtKB/TrEMBL
Pfam PRDM2_PR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mecom PhenoGen
PROSITE SET UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SET UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF82199 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A5H1ZRN1 ENTREZGENE, UniProtKB/TrEMBL
  A4QPC8_MOUSE UniProtKB/TrEMBL
  F6SZX1 ENTREZGENE, UniProtKB/TrEMBL
  G3UWJ0 ENTREZGENE, UniProtKB/TrEMBL
  G3UWT0 ENTREZGENE
  G3UY46_MOUSE UniProtKB/TrEMBL
  G3UYK2 ENTREZGENE, UniProtKB/TrEMBL
  G3UYN3_MOUSE UniProtKB/TrEMBL
  G3UYY9_MOUSE UniProtKB/TrEMBL
  G3UZ13 ENTREZGENE, UniProtKB/TrEMBL
  G3UZT5 ENTREZGENE, UniProtKB/TrEMBL
  H9T841 ENTREZGENE, UniProtKB/TrEMBL
  MECOM_MOUSE UniProtKB/Swiss-Prot
  O35700 ENTREZGENE, UniProtKB/TrEMBL
  P14404 ENTREZGENE
  Q8BQB3_MOUSE UniProtKB/TrEMBL
  Q8C763_MOUSE UniProtKB/TrEMBL
  Q8CCA6 ENTREZGENE, UniProtKB/TrEMBL
  Q9Z1L8 ENTREZGENE
UniProt Secondary G3UWT0 UniProtKB/Swiss-Prot
  Q9Z1L8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-22 Mecom  MDS1 and EVI1 complex locus  Mds1  myelodysplasia syndrome 1 homolog (human)  Data merged from RGD:1319409 737654 PROVISIONAL