Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Hvcn1 | Mouse | 1,1-dichloroethene | increases expression | EXP | | 6480464 | vinylidene chloride results in increased expression of HVCN1 mRNA | CTD | PMID:26682919 | Hvcn1 | Mouse | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of HVCN1 mRNA | CTD | PMID:22206623 | Hvcn1 | Mouse | 17beta-estradiol | multiple interactions | ISO | Hvcn1 (Rattus norvegicus) | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of HVCN1 mRNA | CTD | PMID:32741896 | Hvcn1 | Mouse | 17beta-estradiol 3-benzoate | multiple interactions | ISO | Hvcn1 (Rattus norvegicus) | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of HVCN1 mRNA | CTD | PMID:32741896 | Hvcn1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of HVCN1 mRNA | CTD | PMID:22574217 | Hvcn1 | Mouse | 4,4'-sulfonyldiphenol | decreases methylation | EXP | | 6480464 | bisphenol S results in decreased methylation of HVCN1 exon | CTD | PMID:33297965 | Hvcn1 | Mouse | 4-hydroxyphenyl retinamide | decreases expression | EXP | | 6480464 | Fenretinide results in decreased expression of HVCN1 mRNA | CTD | PMID:28973697 | Hvcn1 | Mouse | 5-aza-2'-deoxycytidine | increases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Decitabine results in increased expression of HVCN1 mRNA | CTD | PMID:21856257 | Hvcn1 | Mouse | all-trans-retinoic acid | decreases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of HVCN1 mRNA | CTD | PMID:33167477 | Hvcn1 | Mouse | alpha-Zearalanol | increases expression | ISO | Hvcn1 (Rattus norvegicus) | 6480464 | Zeranol results in increased expression of HVCN1 mRNA | CTD | PMID:35163327 | Hvcn1 | Mouse | amphetamine | decreases expression | ISO | Hvcn1 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of HVCN1 mRNA | CTD | PMID:30779732 | Hvcn1 | Mouse | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of HVCN1 mRNA] | CTD | PMID:22228805 | Hvcn1 | Mouse | benzo[a]pyrene | increases methylation | ISO | HVCN1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of HVCN1 exon and Benzo(a)pyrene results in increased methylation of HVCN1 promoter | CTD | PMID:27901495 | Hvcn1 | Mouse | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of HVCN1 mRNA | CTD | PMID:22228805 and PMID:32417428 | Hvcn1 | Mouse | bis(2-ethylhexyl) phthalate | decreases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of HVCN1 mRNA | CTD | PMID:31163220 | Hvcn1 | Mouse | bisphenol A | decreases expression | ISO | Hvcn1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of HVCN1 mRNA | CTD | PMID:25181051 | Hvcn1 | Mouse | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of HVCN1 mRNA | CTD | PMID:35479511 | Hvcn1 | Mouse | cadmium dichloride | decreases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of HVCN1 mRNA | CTD | PMID:38382870 | Hvcn1 | Mouse | carbon nanotube | affects expression | EXP | | 6480464 | Nanotubes and Carbon affects the expression of HVCN1 mRNA | CTD | PMID:25554681 | Hvcn1 | Mouse | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in increased expression of HVCN1 mRNA | CTD | PMID:25554681 | Hvcn1 | Mouse | CGP 52608 | multiple interactions | ISO | HVCN1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to HVCN1 gene] | CTD | PMID:28238834 | Hvcn1 | Mouse | chlordecone | increases expression | EXP | | 6480464 | Chlordecone results in increased expression of HVCN1 mRNA | CTD | PMID:33711761 | Hvcn1 | Mouse | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of HVCN1 mRNA | CTD | PMID:20938992 | Hvcn1 | Mouse | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of HVCN1 mRNA | CTD | PMID:28472532 | Hvcn1 | Mouse | cisplatin | increases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of HVCN1 mRNA | CTD | PMID:27594783 | Hvcn1 | Mouse | cocaine | decreases expression | ISO | Hvcn1 (Rattus norvegicus) | 6480464 | Cocaine results in decreased expression of HVCN1 mRNA | CTD | PMID:27899881 | Hvcn1 | Mouse | crocidolite asbestos | decreases expression | EXP | | 6480464 | Asbestos and Crocidolite results in decreased expression of HVCN1 mRNA | CTD | PMID:29279043 | Hvcn1 | Mouse | Cuprizon | increases expression | ISO | Hvcn1 (Rattus norvegicus) | 6480464 | Cuprizone results in increased expression of HVCN1 mRNA | CTD | PMID:27523638 | Hvcn1 | Mouse | dimethylarsinic acid | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of HVCN1 mRNA | CTD | PMID:34876320 | Hvcn1 | Mouse | dioxygen | multiple interactions | EXP | | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of HVCN1 mRNA | CTD | PMID:30529165 | Hvcn1 | Mouse | endosulfan | increases expression | ISO | Hvcn1 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of HVCN1 mRNA | CTD | PMID:29391264 | Hvcn1 | Mouse | ethyl methanesulfonate | decreases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of HVCN1 mRNA | CTD | PMID:23649840 | Hvcn1 | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of HVCN1 mRNA | CTD | PMID:20938992 | Hvcn1 | Mouse | formaldehyde | decreases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of HVCN1 mRNA | CTD | PMID:23649840 | Hvcn1 | Mouse | genistein | increases expression | EXP | | 6480464 | Genistein results in increased expression of HVCN1 mRNA | CTD | PMID:32186404 | Hvcn1 | Mouse | gentamycin | increases expression | ISO | Hvcn1 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of HVCN1 mRNA | CTD | PMID:33387578 | Hvcn1 | Mouse | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of HVCN1 mRNA | CTD | PMID:20938992 | Hvcn1 | Mouse | lidocaine | increases expression | ISO | Hvcn1 (Rattus norvegicus) | 6480464 | Lidocaine results in increased expression of HVCN1 mRNA | CTD | PMID:35283115 | Hvcn1 | Mouse | methyl methanesulfonate | decreases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of HVCN1 mRNA | CTD | PMID:23649840 | Hvcn1 | Mouse | methylarsonic acid | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of HVCN1 mRNA | CTD | PMID:34876320 | Hvcn1 | Mouse | nickel atom | decreases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Nickel results in decreased expression of HVCN1 mRNA | CTD | PMID:23195993 | Hvcn1 | Mouse | niclosamide | increases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Niclosamide results in increased expression of HVCN1 mRNA | CTD | PMID:36318118 | Hvcn1 | Mouse | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of HVCN1 mRNA | CTD | PMID:34911549 | Hvcn1 | Mouse | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of HVCN1 mRNA | CTD | PMID:17562736 | Hvcn1 | Mouse | paracetamol | increases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of HVCN1 mRNA | CTD | PMID:26690555 | Hvcn1 | Mouse | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of HVCN1 mRNA | CTD | PMID:29203145 | Hvcn1 | Mouse | sodium arsenate | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of HVCN1 mRNA | CTD | PMID:34876320 | Hvcn1 | Mouse | sodium arsenite | affects methylation | ISO | HVCN1 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of HVCN1 gene | CTD | PMID:28589171 | Hvcn1 | Mouse | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of HVCN1 mRNA | CTD | PMID:37682722 | Hvcn1 | Mouse | sodium arsenite | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of HVCN1 mRNA | CTD | PMID:34876320 | Hvcn1 | Mouse | sodium arsenite | increases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of HVCN1 mRNA | CTD | PMID:38568856 | Hvcn1 | Mouse | testosterone | multiple interactions | ISO | Hvcn1 (Rattus norvegicus) | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of HVCN1 mRNA | CTD | PMID:32741896 | Hvcn1 | Mouse | testosterone | decreases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of HVCN1 mRNA | CTD | PMID:33359661 | Hvcn1 | Mouse | thioacetamide | increases expression | ISO | Hvcn1 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of HVCN1 mRNA | CTD | PMID:34492290 | Hvcn1 | Mouse | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of HVCN1 mRNA | CTD | PMID:23557971 | Hvcn1 | Mouse | trichloroethene | increases expression | ISO | Hvcn1 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of HVCN1 mRNA | CTD | PMID:33387578 | Hvcn1 | Mouse | triclosan | increases expression | ISO | HVCN1 (Homo sapiens) | 6480464 | Triclosan results in increased expression of HVCN1 mRNA | CTD | PMID:30510588 | Hvcn1 | Mouse | triphenyl phosphate | affects expression | ISO | HVCN1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of HVCN1 mRNA | CTD | PMID:37042841 | Hvcn1 | Mouse | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of HVCN1 mRNA | CTD | PMID:21427059 | Hvcn1 | Mouse | valproic acid | increases methylation | ISO | HVCN1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of HVCN1 gene | CTD | PMID:29154799 | |