Vmn2r81 (vomeronasal 2, receptor 81) - Rat Genome Database

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Gene: Vmn2r81 (vomeronasal 2, receptor 81) Mus musculus
Analyze
No known orthologs.
Symbol: Vmn2r81
Name: vomeronasal 2, receptor 81
RGD ID: 1321564
MGI Page MGI
Description: Enables G protein-coupled olfactory receptor activity. Acts upstream of or within neuron differentiation and phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AJ543404; cDNA sequence AJ543403; cdna sequence aj543404; EC1-V; EC1-V2R; EC1-V2R pheromone receptor; EC1-VR2; pheromone recepter; V2r; V2rf2
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,083,611 - 79,130,369 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1079,083,526 - 79,130,369 (+)EnsemblGRCm39 Ensembl
GRCm381079,247,777 - 79,294,535 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,247,692 - 79,294,535 (+)EnsemblGRCm38mm10GRCm38
MGSCv371078,710,522 - 78,757,280 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361078,650,904 - 78,697,664 (+)NCBIMGSCv36mm8
Celera1080,266,765 - 80,313,483 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12628182   PMID:14610273   PMID:17382427   PMID:18322080   PMID:21112400   PMID:21267068   PMID:21873635   PMID:23006775   PMID:24719092   PMID:29465786  


Genomics

Variants

.
Variants in Vmn2r81
1638 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:171
Count of miRNA genes:151
Interacting mature miRNAs:154
Transcripts:ENSMUST00000020547
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106684818792258673Mouse
1300882Ath17_matherosclerosis 17 (mouse)Not determined105109149085091639Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75338568109338767Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105851696992517096Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
14746991Manh68_mmandible shape 68 (mouse)105228049786280497Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1302150Bbaa18_mB.burgdorferi-associated arthritis 18 (mouse)Not determined104933801283338157Mouse
1301380Cia8_mcollagen induced arthritis QTL 8 (mouse)Not determined105149340082491121Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1044876096115935905Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073506901107507047Mouse
4142107Obrq12_mobesity resistance QTL 12 (mouse)Not determined7398721682491121Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106549093899491121Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078381268112381268Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
13208560Wght9_mweight 9 (mouse)1059835822120835905Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
1357737Hpcr2_mhepatocarcinogen resistance 2 (mouse)Not determined104984822283848397Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106549093899491121Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067335830111735905Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
10045641Jckm3_mjuvenile cystic kidney modifier 3 (mouse)Not determined104984818783848412Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1063935779115935905Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075338568109338767Mouse
4142313Angvq1_mangiogenesis by VEGF QTL 1 (mouse)Not determined4672040382491121Mouse
1301966Lifespan2_mlife span 2 (mouse)Not determined104984822283848397Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse
1300597Skull14_mskull morphology 14 (mouse)Not determined104984818783848412Mouse
4142169Pbwg16_mpostnatal body weight growth 16 (mouse)Not determined104984818783848412Mouse
1301502Eae17_msusceptibility to experimental allergic encephalomyelitis 17 (mouse)Not determined105109149085091639Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106549093899491121Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075338568109338767Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000020547   ⟹   ENSMUSP00000020547
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1079,083,526 - 79,130,369 (+)Ensembl
GRCm38.p6 Ensembl1079,247,692 - 79,294,535 (+)Ensembl
RefSeq Acc Id: NM_175936   ⟹   NP_787950
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391079,083,611 - 79,130,369 (+)NCBI
GRCm381079,247,777 - 79,294,535 (+)ENTREZGENE
MGSCv371078,710,522 - 78,757,280 (+)RGD
Celera1080,266,765 - 80,313,483 (+)RGD
cM Map10 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_787950 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAD65886 (Get FASTA)   NCBI Sequence Viewer  
  EDL31704 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000020547
  ENSMUSP00000020547.9
RefSeq Acc Id: NP_787950   ⟸   NM_175936
- Peptide Label: precursor
- UniProtKB: Q80Z09 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000020547   ⟸   ENSMUST00000020547
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80Z09-F1-model_v2 AlphaFold Q80Z09 1-865 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2684056 AgrOrtholog
Ensembl Genes ENSMUSG00000055515 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020547 ENTREZGENE
  ENSMUST00000020547.10 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_Ca_sens_rcpt-rel UniProtKB/TrEMBL
  GPCR_3_vmron_rcpt_2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
KEGG Report mmu:216144 UniProtKB/TrEMBL
MGD MGI:2684056 ENTREZGENE
NCBI Gene Vmn2r81 ENTREZGENE
PANTHER EC1-V2R PHEROMONE RECEPTOR PROTEIN-RELATED UniProtKB/TrEMBL
  PTHR24061 UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PhenoGen Vmn2r81 PhenoGen
PRINTS GPCRMGR UniProtKB/TrEMBL
  VOMERONASL2R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt Q80Z09 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Vmn2r81  vomeronasal 2, receptor 81  AJ543404  cDNA sequence AJ543404  Symbol and/or name change 5135510 APPROVED
2024-08-21 AJ543404  cDNA sequence AJ543404  Vmn2r81  vomeronasal 2, receptor 81  Symbol and/or name change 5135510 APPROVED