Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Frmd8 | Mouse | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of FRMD8 mRNA | CTD | PMID:22206623 | Frmd8 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FRMD8 mRNA | CTD | PMID:21570461 | Frmd8 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FRMD8 mRNA | CTD | PMID:33387578 | Frmd8 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of FRMD8 mRNA | CTD | PMID:25975270 | Frmd8 | Mouse | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of FRMD8 mRNA | CTD | PMID:20188158 | Frmd8 | Mouse | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of FRMD8 mRNA | CTD | PMID:18648102 | Frmd8 | Mouse | 5-aza-2'-deoxycytidine | affects expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Decitabine affects the expression of FRMD8 mRNA | CTD | PMID:23300844 | Frmd8 | Mouse | acetamide | increases expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | acetamide results in increased expression of FRMD8 mRNA | CTD | PMID:31881176 | Frmd8 | Mouse | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of FRMD8 mRNA | CTD | PMID:19770486 | Frmd8 | Mouse | aflatoxin B1 | decreases methylation | ISO | FRMD8 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of FRMD8 3' UTR | CTD | PMID:30157460 | Frmd8 | Mouse | aflatoxin B1 | increases expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | Aflatoxin B1 results in increased expression of FRMD8 mRNA | CTD | PMID:22484513 | Frmd8 | Mouse | aristolochic acid A | increases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of FRMD8 mRNA | CTD | PMID:33212167 | Frmd8 | Mouse | atrazine | decreases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of FRMD8 mRNA | CTD | PMID:22378314 | Frmd8 | Mouse | benzo[a]pyrene | increases methylation | ISO | FRMD8 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of FRMD8 promoter | CTD | PMID:27901495 | Frmd8 | Mouse | benzo[a]pyrene | increases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of FRMD8 mRNA | CTD | PMID:32234424 | Frmd8 | Mouse | benzo[e]pyrene | decreases methylation | ISO | FRMD8 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of FRMD8 intron | CTD | PMID:30157460 | Frmd8 | Mouse | beta-lapachone | decreases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of FRMD8 mRNA | CTD | PMID:38218311 | Frmd8 | Mouse | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FRMD8 mRNA | CTD | PMID:21932408 and PMID:33221593 | Frmd8 | Mouse | bisphenol A | decreases expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of FRMD8 mRNA | CTD | PMID:34947998 | Frmd8 | Mouse | bisphenol A | affects expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of FRMD8 mRNA | CTD | PMID:25181051 | Frmd8 | Mouse | butanal | increases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of FRMD8 mRNA | CTD | PMID:26079696 | Frmd8 | Mouse | cadmium atom | increases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Cadmium results in increased expression of FRMD8 mRNA | CTD | PMID:24376830 | Frmd8 | Mouse | cadmium dichloride | decreases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of FRMD8 mRNA | CTD | PMID:38568856 | Frmd8 | Mouse | caffeine | decreases phosphorylation | ISO | FRMD8 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of FRMD8 protein | CTD | PMID:35688186 | Frmd8 | Mouse | CGP 52608 | multiple interactions | ISO | FRMD8 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to FRMD8 gene] | CTD | PMID:28238834 | Frmd8 | Mouse | chlordecone | increases expression | EXP | | 6480464 | Chlordecone results in increased expression of FRMD8 mRNA | CTD | PMID:29980752 | Frmd8 | Mouse | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of FRMD8 mRNA | CTD | PMID:37019170 | Frmd8 | Mouse | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of FRMD8 mRNA | CTD | PMID:28472532 | Frmd8 | Mouse | cisplatin | affects expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Cisplatin affects the expression of FRMD8 mRNA | CTD | PMID:23300844 | Frmd8 | Mouse | cisplatin | multiple interactions | ISO | FRMD8 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of FRMD8 mRNA | CTD | PMID:27392435 | Frmd8 | Mouse | cisplatin | increases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of FRMD8 mRNA | CTD | PMID:27392435 | Frmd8 | Mouse | clobetasol | increases expression | EXP | | 6480464 | Clobetasol results in increased expression of FRMD8 mRNA | CTD | PMID:27462272 | Frmd8 | Mouse | clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of FRMD8 mRNA | CTD | PMID:23811191 | Frmd8 | Mouse | crocidolite asbestos | increases expression | EXP | | 6480464 | Asbestos and Crocidolite results in increased expression of FRMD8 mRNA | CTD | PMID:29279043 | Frmd8 | Mouse | Cuprizon | increases expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | Cuprizone results in increased expression of FRMD8 mRNA | CTD | PMID:26577399 and PMID:27523638 | Frmd8 | Mouse | Dibutyl phosphate | affects expression | ISO | FRMD8 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of FRMD8 mRNA | CTD | PMID:37042841 | Frmd8 | Mouse | dibutyl phthalate | decreases expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in decreased expression of FRMD8 mRNA | CTD | PMID:21266533 | Frmd8 | Mouse | dibutyl phthalate | increases expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in increased expression of FRMD8 mRNA | CTD | PMID:21266533 | Frmd8 | Mouse | diquat | decreases expression | EXP | | 6480464 | Diquat results in decreased expression of FRMD8 protein | CTD | PMID:36851058 | Frmd8 | Mouse | diuron | decreases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Diuron results in decreased expression of FRMD8 mRNA | CTD | PMID:35967413 | Frmd8 | Mouse | doxorubicin | decreases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of FRMD8 mRNA | CTD | PMID:29803840 | Frmd8 | Mouse | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of FRMD8 mRNA | CTD | PMID:30319688 | Frmd8 | Mouse | ethyl methanesulfonate | increases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of FRMD8 mRNA | CTD | PMID:23649840 | Frmd8 | Mouse | fenamidone | increases expression | EXP | | 6480464 | fenamidone results in increased expression of FRMD8 mRNA | CTD | PMID:27029645 | Frmd8 | Mouse | formaldehyde | increases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of FRMD8 mRNA | CTD | PMID:23649840 | Frmd8 | Mouse | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of FRMD8 mRNA | CTD | PMID:36331819 | Frmd8 | Mouse | iron dichloride | decreases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of FRMD8 mRNA | CTD | PMID:35984750 | Frmd8 | Mouse | leflunomide | decreases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of FRMD8 mRNA | CTD | PMID:28988120 | Frmd8 | Mouse | methapyrilene | decreases methylation | ISO | FRMD8 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of FRMD8 intron | CTD | PMID:30157460 | Frmd8 | Mouse | methotrexate | decreases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Methotrexate results in decreased expression of FRMD8 mRNA | CTD | PMID:24449571 | Frmd8 | Mouse | methoxychlor | affects methylation | ISO | Frmd8 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of FRMD8 gene | CTD | PMID:35440735 | Frmd8 | Mouse | methyl methanesulfonate | increases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of FRMD8 mRNA | CTD | PMID:23649840 | Frmd8 | Mouse | ozone | multiple interactions | ISO | FRMD8 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of FRMD8 mRNA | CTD | PMID:35430440 | Frmd8 | Mouse | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of FRMD8 mRNA | CTD | PMID:17562736 | Frmd8 | Mouse | paracetamol | increases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of FRMD8 mRNA | CTD | PMID:22230336 | Frmd8 | Mouse | paraquat | increases expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | Paraquat results in increased expression of FRMD8 mRNA | CTD | PMID:32680482 | Frmd8 | Mouse | pentanal | increases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | pentanal results in increased expression of FRMD8 mRNA | CTD | PMID:26079696 | Frmd8 | Mouse | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of FRMD8 mRNA | CTD | PMID:36331819 | Frmd8 | Mouse | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of FRMD8 mRNA | CTD | PMID:23811191 | Frmd8 | Mouse | propanal | increases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of FRMD8 mRNA | CTD | PMID:26079696 | Frmd8 | Mouse | resveratrol | multiple interactions | ISO | FRMD8 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of FRMD8 mRNA | CTD | PMID:23557933 | Frmd8 | Mouse | silicon dioxide | increases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of FRMD8 mRNA | CTD | PMID:25895662 | Frmd8 | Mouse | Soman | increases expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | Soman results in increased expression of FRMD8 mRNA | CTD | PMID:19281266 | Frmd8 | Mouse | tamoxifen | increases expression | EXP | | 6480464 | Tamoxifen results in increased expression of FRMD8 mRNA | CTD | PMID:25123088 | Frmd8 | Mouse | thioacetamide | increases expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of FRMD8 mRNA | CTD | PMID:23411599 and PMID:34492290 | Frmd8 | Mouse | triphenyl phosphate | affects expression | ISO | FRMD8 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of FRMD8 mRNA | CTD | PMID:37042841 | Frmd8 | Mouse | urethane | decreases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Urethane results in decreased expression of FRMD8 mRNA | CTD | PMID:28818685 | Frmd8 | Mouse | valproic acid | increases expression | ISO | FRMD8 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of FRMD8 mRNA | CTD | PMID:23179753 and PMID:24935251 | Frmd8 | Mouse | vinclozolin | increases expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of FRMD8 mRNA | CTD | PMID:22570695 | Frmd8 | Mouse | vinclozolin | decreases expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased expression of FRMD8 mRNA | CTD | PMID:23034163 | Frmd8 | Mouse | vinclozolin | affects expression | ISO | Frmd8 (Rattus norvegicus) | 6480464 | vinclozolin affects the expression of FRMD8 mRNA | CTD | PMID:19015723 | Frmd8 | Mouse | zinc atom | multiple interactions | ISO | FRMD8 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of FRMD8 mRNA | CTD | PMID:18593933 | Frmd8 | Mouse | zinc(0) | multiple interactions | ISO | FRMD8 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of FRMD8 mRNA | CTD | PMID:18593933 | |