Tfap2a (transcription factor AP-2, alpha) - Rat Genome Database

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Gene: Tfap2a (transcription factor AP-2, alpha) Mus musculus
Analyze
Symbol: Tfap2a
Name: transcription factor AP-2, alpha
RGD ID: 1321068
MGI Page MGI
Description: Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; transcription coactivator activity; and transcription corepressor activity. Involved in several processes, including cranial nerve development; embryonic morphogenesis; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including camera-type eye development; face morphogenesis; and nervous system development. Located in clathrin-coated pit and nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; jaw; nervous system; and sensory organ. Used to study orofacial cleft. Human ortholog(s) of this gene implicated in branchiooculofacial syndrome. Orthologous to human TFAP2A (transcription factor AP-2 alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: A; activating enhancer-binding protein 2 alpha; activating enhancer-binding protein 2-alpha; activator protein 2; AP; AP-2; Ap-2 (a); AP-2 alpha; AP-2 transcription factor; Ap2; AP2-alpha; AP2alpha; Ap2tf; Tcfa; Tcfap2a; transcription factor AP-2; transcription factor AP-2-alpha
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391340,867,278 - 40,891,715 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1340,868,778 - 40,891,852 (-)EnsemblGRCm39 Ensembl
GRCm381340,713,802 - 40,738,238 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1340,715,302 - 40,738,376 (-)EnsemblGRCm38mm10GRCm38
MGSCv371340,811,044 - 40,829,192 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361340,727,706 - 40,745,894 (-)NCBIMGSCv36mm8
Celera1341,797,334 - 41,815,714 (-)NCBICelera
Cytogenetic Map13A3.3NCBI
cM Map1320.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (EXP)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
15-acetyldeoxynivalenol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
arotinoid acid  (ISO)
arsenite(3-)  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP)
bisphenol F  (EXP)
butan-1-ol  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (EXP)
calcitriol  (ISO)
cannabidiol  (EXP)
carboplatin  (ISO)
CHIR 99021  (ISO)
chlorpyrifos  (EXP)
choline  (EXP)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
clomiphene  (ISO)
cortisol  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
cytarabine  (EXP)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP)
dibutyl phthalate  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
erlotinib hydrochloride  (ISO)
ethanol  (ISO)
etoposide  (ISO)
fenpropidin  (EXP)
flusilazole  (EXP)
folic acid  (EXP)
fulvestrant  (ISO)
furan  (ISO)
gefitinib  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
hexestrol  (ISO)
ifosfamide  (ISO)
indinavir  (EXP)
kahweol  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
L-methionine  (EXP)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
mercury dibromide  (ISO)
mestranol  (ISO)
methamphetamine  (ISO)
methotrexate  (EXP)
methylmercury chloride  (ISO)
methylparaben  (ISO)
mitomycin C  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
nickel subsulfide  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paclitaxel  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
paroxetine  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
rottlerin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sertraline  (ISO)
spiroxamine  (EXP)
stavudine  (EXP)
streptozocin  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
Tetrachlorobisphenol A  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
troglitazone  (ISO)
tyrphostin AG 1478  (ISO)
valproic acid  (EXP,ISO)
vincristine  (ISO)
vorinostat  (ISO)
XAV939  (ISO)
zidovudine  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anatomical structure development  (IBA)
anterior neuropore closure  (IMP)
basement membrane organization  (IMP)
bone morphogenesis  (IMP)
cell population proliferation  (IMP)
cellular response to iron ion  (ISO)
cornea development in camera-type eye  (IMP)
embryonic body morphogenesis  (IMP)
embryonic camera-type eye morphogenesis  (IMP)
embryonic cranial skeleton morphogenesis  (IMP)
embryonic forelimb morphogenesis  (IMP)
embryonic pattern specification  (IMP)
epidermal growth factor receptor signaling pathway  (IMP)
epidermis morphogenesis  (IMP)
eyelid development in camera-type eye  (IMP)
face morphogenesis  (IMP)
fibroblast migration  (IMP)
forebrain neuron development  (IMP)
forelimb morphogenesis  (IMP)
inner ear morphogenesis  (ISO)
keratinocyte development  (IGI)
kidney development  (ISO)
lens induction in camera-type eye  (IMP)
lens morphogenesis in camera-type eye  (IMP)
metanephric nephron development  (IEP)
negative regulation of apoptotic process  (ISO)
negative regulation of cell population proliferation  (IMP,ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of epidermal growth factor receptor signaling pathway  (IMP)
negative regulation of neuron apoptotic process  (IGI)
negative regulation of reactive oxygen species metabolic process  (ISO)
negative regulation of transcription by competitive promoter binding  (ISO)
negative regulation of transcription by RNA polymerase II  (IDA,ISO)
nervous system development  (IEP)
neural crest cell development  (IMP)
neural tube closure  (IMP)
neuron apoptotic process  (IGI)
oculomotor nerve formation  (IMP)
optic cup structural organization  (IMP)
optic vesicle morphogenesis  (IMP)
outflow tract morphogenesis  (IMP)
positive regulation of bone mineralization  (ISO)
positive regulation of DNA-templated transcription  (IDA,ISO)
positive regulation of fibroblast migration  (IMP)
positive regulation of gene expression  (IDA)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of tooth mineralization  (ISO)
positive regulation of transcription by RNA polymerase II  (IDA,ISO)
regulation of cell differentiation  (ISO)
regulation of cell population proliferation  (IBA)
regulation of DNA-templated transcription  (IDA)
regulation of neuron differentiation  (IMP)
regulation of transcription by RNA polymerase II  (IBA,IDA)
response to lipopolysaccharide  (ISO)
response to organic substance  (ISO)
retina layer formation  (ISO)
roof of mouth development  (ISO)
Schwann cell development  (ISO)
sensory organ development  (IEP)
sensory perception of sound  (ISO)
skeletal system morphogenesis  (IMP)
skin development  (IEP,IGI)
sympathetic nervous system development  (IGI)
transcription by RNA polymerase II  (IDA)
trigeminal nerve development  (IMP)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
aberrant origin of the right subclavian artery  (IAGP)
abnormal adrenal gland secretion  (IAGP)
abnormal aortic arch development  (IAGP)
abnormal aortic arch morphology  (IAGP)
abnormal apoptosis  (IAGP)
abnormal axial skeleton morphology  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal cardiac neural crest cell morphology  (IAGP)
abnormal cardiac outflow tract development  (IAGP)
abnormal cartilage morphology  (IAGP)
abnormal cell death  (IAGP)
abnormal cochlear ganglion morphology  (IAGP)
abnormal cornea morphology  (IAGP)
abnormal coronary artery morphology  (IAGP)
abnormal cranial ganglia morphology  (IAGP)
abnormal cranial nerve morphology  (IAGP)
abnormal craniofacial development  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal dorsal-ventral axis patterning  (IAGP)
abnormal embryonic tissue morphology  (IAGP)
abnormal extraembryonic tissue morphology  (IAGP)
abnormal facial morphology  (IAGP)
abnormal facial nerve morphology  (IAGP)
abnormal facial skin morphology  (IAGP)
abnormal foot pigmentation  (IAGP)
abnormal forebrain morphology  (IAGP)
abnormal fourth pharyngeal arch artery morphology  (IAGP)
abnormal frontonasal suture morphology  (IAGP)
abnormal glossopharyngeal ganglion morphology  (IAGP)
abnormal head morphology  (IAGP)
abnormal heart valve morphology  (IAGP)
abnormal heart ventricle outflow tract morphology  (IAGP)
abnormal hyoid bone morphology  (IAGP)
abnormal incus morphology  (IAGP)
abnormal iris morphology  (IAGP)
abnormal lateral nasal prominence morphology  (IAGP)
abnormal lens induction  (IAGP)
abnormal lens morphology  (IAGP)
abnormal lens vesicle development  (IAGP)
abnormal malleus morphology  (IAGP)
abnormal mandible morphology  (IAGP)
abnormal maxilla morphology  (IAGP)
abnormal maxillary prominence morphology  (IAGP)
abnormal medial nasal prominence morphology  (IAGP)
abnormal middle ear ossicle morphology  (IAGP)
abnormal midface morphology  (IAGP)
abnormal nasal bone morphology  (IAGP)
abnormal nasal pit morphology  (IAGP)
abnormal nasal septum cartilage morphology  (IAGP)
abnormal neural crest cell apoptosis  (IAGP)
abnormal neural fold elevation formation  (IAGP)
abnormal neural tube closure  (IAGP)
abnormal neurocranium morphology  (IAGP)
abnormal optic fissure closure  (IAGP)
abnormal optic stalk morphology  (IAGP)
abnormal otic capsule morphology  (IAGP)
abnormal palatal shelf fusion at midline  (IAGP)
abnormal palate morphology  (IAGP)
abnormal parietal bone morphology  (IAGP)
abnormal periorbital skin morphology  (IAGP)
abnormal pharyngeal arch artery morphology  (IAGP)
abnormal pinna reflex  (IAGP)
abnormal premaxilla morphology  (IAGP)
abnormal retina pigment epithelium morphology  (IAGP)
abnormal secondary palate morphology  (IAGP)
abnormal stapes morphology  (IAGP)
abnormal subclavian artery morphology  (IAGP)
abnormal tail pigmentation  (IAGP)
abnormal thoracic cage morphology  (IAGP)
abnormal tongue muscle morphology  (IAGP)
abnormal trigeminal nerve morphology  (IAGP)
abnormal truncus arteriosus septation  (IAGP)
abnormal vagus ganglion morphology  (IAGP)
abnormal ventral body wall morphology  (IAGP)
abnormal vestibular ganglion morphology  (IAGP)
abnormal vestibulocochlear nerve morphology  (IAGP)
abnormal zygomatic bone morphology  (IAGP)
absent clavicle  (IAGP)
absent eyelids  (IAGP)
absent fourth pharyngeal arch artery  (IAGP)
absent interparietal bone  (IAGP)
absent maxilla  (IAGP)
absent middle ear ossicles  (IAGP)
absent mouth  (IAGP)
absent nasal bone  (IAGP)
absent oculomotor nerve  (IAGP)
absent outer ear  (IAGP)
absent parietal bone  (IAGP)
absent pericardium  (IAGP)
absent pinna reflex  (IAGP)
absent radius  (IAGP)
absent retina ganglion layer  (IAGP)
absent sixth pharyngeal arch artery  (IAGP)
absent snout  (IAGP)
absent startle reflex  (IAGP)
absent sternum  (IAGP)
absent tympanic ring  (IAGP)
acrania  (IAGP)
anencephaly  (IAGP)
aniridia  (IAGP)
anophthalmia  (IAGP)
athymia  (IAGP)
belly spot  (IAGP)
broad nasal bone  (IAGP)
cleft palate  (IAGP)
cleft primary palate  (IAGP)
conductive hearing loss  (IAGP)
cranioschisis  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased cochlear nerve compound action potential  (IAGP)
decreased cornea thickness  (IAGP)
decreased embryo size  (IAGP)
decreased motor neuron number  (IAGP)
decreased tongue size  (IAGP)
double outlet right ventricle  (IAGP)
embryonic lethality between implantation and somite formation, incomplete penetrance  (IAGP)
enlarged third pharyngeal arch artery  (IAGP)
exencephaly  (IAGP)
facial cleft  (IAGP)
failure of eyelid fusion  (IAGP)
fourth pharyngeal arch artery hypoplasia  (IAGP)
incomplete rostral neuropore closure  (IAGP)
interrupted aortic arch  (IAGP)
malocclusion  (IAGP)
midline facial cleft  (IAGP)
narrow snout  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
ocular hypertelorism  (IAGP)
open neural tube  (IAGP)
perinatal lethality  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
persistent right dorsal aorta  (IAGP)
persistent truncus arteriosis  (IAGP)
pharyngeal arch hypoplasia  (IAGP)
polydactyly  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
pulmonary valve atresia  (IAGP)
pulmonary valve stenosis  (IAGP)
pup cannibalization  (IAGP)
respiratory distress  (IAGP)
retina fold  (IAGP)
retroesophageal right subclavian artery  (IAGP)
right aortic arch  (IAGP)
scoliosis  (IAGP)
short frontal bone  (IAGP)
short mandible  (IAGP)
short maxilla  (IAGP)
short nasal bone  (IAGP)
short snout  (IAGP)
small frontal bone  (IAGP)
small lens  (IAGP)
small orbits  (IAGP)
small trigeminal ganglion  (IAGP)
small zygomatic bone  (IAGP)
splayed ribs  (IAGP)
thoracoabdominoschisis  (IAGP)
thymus hypoplasia  (IAGP)
unilateral cleft palate  (IAGP)
ventricular septal defect  (IAGP)
wide frontal bone  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Transcription factor AP-2alpha triggers apoptosis in cardiac myocytes. Muller FU, etal., Cell Death Differ. 2004 May;11(5):485-93.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1295734   PMID:1989904   PMID:3063603   PMID:7477375   PMID:7525178   PMID:7555706   PMID:7729687   PMID:7750631   PMID:8233835   PMID:8622765   PMID:8622766   PMID:8692702  
PMID:8808408   PMID:8824807   PMID:8885715   PMID:8989526   PMID:9006062   PMID:9271117   PMID:9284043   PMID:9353119   PMID:9463359   PMID:9758708   PMID:9765260   PMID:9811866  
PMID:9858544   PMID:9918694   PMID:10068641   PMID:10079226   PMID:10079236   PMID:10349636   PMID:10529420   PMID:10571739   PMID:10588870   PMID:10625532   PMID:10655590   PMID:10662648  
PMID:10803593   PMID:10842061   PMID:10932192   PMID:10946068   PMID:11042159   PMID:11076861   PMID:11118892   PMID:11137286   PMID:11319856   PMID:11406614   PMID:11518511   PMID:11522791  
PMID:11553286   PMID:11598925   PMID:11688971   PMID:11694877   PMID:11741941   PMID:11744375   PMID:11784076   PMID:11967920   PMID:11969252   PMID:12062896   PMID:12223415   PMID:12223417  
PMID:12438097   PMID:12466851   PMID:12477932   PMID:12504852   PMID:12514106   PMID:12522767   PMID:12586840   PMID:12619893   PMID:12654297   PMID:12694203   PMID:12711551   PMID:12749383  
PMID:12839558   PMID:12878728   PMID:14572467   PMID:14623825   PMID:14651926   PMID:14969394   PMID:14975718   PMID:14975722   PMID:15013802   PMID:15063181   PMID:15070745   PMID:15136147  
PMID:15148302   PMID:15181535   PMID:15198977   PMID:15328019   PMID:15475956   PMID:15489334   PMID:15581866   PMID:15618518   PMID:15663482   PMID:15680353   PMID:15936751   PMID:15996652  
PMID:16024294   PMID:16102745   PMID:16141072   PMID:16141073   PMID:16186342   PMID:16207751   PMID:16221730   PMID:16368932   PMID:16399079   PMID:16449191   PMID:16672719   PMID:16720880  
PMID:16836994   PMID:16839542   PMID:16887830   PMID:16894609   PMID:16919269   PMID:17042795   PMID:17067568   PMID:17107998   PMID:17344228   PMID:17428831   PMID:17442300   PMID:17519332  
PMID:17670746   PMID:17676634   PMID:17679940   PMID:17724084   PMID:17728348   PMID:17984226   PMID:18224708   PMID:18243171   PMID:18287559   PMID:18330926   PMID:18334251   PMID:18424435  
PMID:18594783   PMID:18653562   PMID:18723448   PMID:18816854   PMID:18824566   PMID:18832392   PMID:18832393   PMID:18836445   PMID:18987029   PMID:19000842   PMID:19141316   PMID:19198652  
PMID:19376641   PMID:19387074   PMID:19420345   PMID:19463168   PMID:19474320   PMID:19509466   PMID:19570848   PMID:19666824   PMID:19685247   PMID:19692620   PMID:19700620   PMID:19700621  
PMID:19705442   PMID:19749747   PMID:19750005   PMID:19782674   PMID:19842069   PMID:19855134   PMID:19943855   PMID:20016822   PMID:20035084   PMID:20059953   PMID:20079728   PMID:20110535  
PMID:20122914   PMID:20144606   PMID:20150232   PMID:20171203   PMID:20175189   PMID:20211142   PMID:20215350   PMID:20412781   PMID:20457670   PMID:20459789   PMID:20459791   PMID:20500056  
PMID:20501333   PMID:20525283   PMID:20529123   PMID:20660060   PMID:20807571   PMID:20847311   PMID:20932939   PMID:20962249   PMID:21070765   PMID:21123999   PMID:21138975   PMID:21157040  
PMID:21177346   PMID:21233129   PMID:21246653   PMID:21256960   PMID:21303954   PMID:21364285   PMID:21377456   PMID:21394823   PMID:21539825   PMID:21543621   PMID:21600894   PMID:21829553  
PMID:21873635   PMID:21978078   PMID:21982646   PMID:22020075   PMID:22040872   PMID:22083510   PMID:22110056   PMID:22116936   PMID:22138056   PMID:22215812   PMID:22240097   PMID:22274697  
PMID:22275127   PMID:22411557   PMID:22451343   PMID:22503753   PMID:22609278   PMID:22848431   PMID:22966238   PMID:22972697   PMID:22988430   PMID:23112163   PMID:23126661   PMID:23171847  
PMID:23201579   PMID:23292680   PMID:23307637   PMID:23307821   PMID:23351706   PMID:23361844   PMID:23393395   PMID:23436026   PMID:23437302   PMID:23592779   PMID:23595746   PMID:23907538  
PMID:23942202   PMID:24068957   PMID:24073291   PMID:24086166   PMID:24125957   PMID:24140542   PMID:24170322   PMID:24198279   PMID:24307298   PMID:24336726   PMID:24374663   PMID:24421398  
PMID:24451200   PMID:24453340   PMID:24590292   PMID:24650709   PMID:24732798   PMID:24753151   PMID:24821700   PMID:24952961   PMID:24996922   PMID:25038041   PMID:25128028   PMID:25166858  
PMID:25242040   PMID:25299188   PMID:25313862   PMID:25381013   PMID:25561690   PMID:25661788   PMID:25758223   PMID:25794677   PMID:25794678   PMID:25800090   PMID:25848030   PMID:25964075  
PMID:25966682   PMID:25989023   PMID:25995483   PMID:26284287   PMID:26287463   PMID:26288816   PMID:26434918   PMID:26437238   PMID:26545946   PMID:26552887   PMID:26722124   PMID:26746790  
PMID:26755698   PMID:26822476   PMID:26839363   PMID:26884322   PMID:26949938   PMID:26968737   PMID:27184845   PMID:27210758   PMID:27259519   PMID:27302397   PMID:27362800   PMID:27385012  
PMID:27391154   PMID:27605619   PMID:27697904   PMID:27777416   PMID:27783871   PMID:27820600   PMID:27906176   PMID:27984181   PMID:28049691   PMID:28179583   PMID:28199486   PMID:28249010  
PMID:28291836   PMID:28346501   PMID:28412966   PMID:28625870   PMID:28714851   PMID:28754980   PMID:28818950   PMID:28898113   PMID:28912684   PMID:28931923   PMID:28982131   PMID:29053761  
PMID:29137925   PMID:29229773   PMID:29258872   PMID:29262337   PMID:29409032   PMID:29467543   PMID:29502204   PMID:29523871   PMID:29539416   PMID:29611808   PMID:29715367   PMID:29913133  
PMID:29922981   PMID:29975682   PMID:30093671   PMID:30127719   PMID:30208054   PMID:30220568   PMID:30242109   PMID:30408103   PMID:30424580   PMID:30630826   PMID:30689861   PMID:30783126  
PMID:30991053   PMID:31087513   PMID:31142747   PMID:31175693   PMID:31232685   PMID:31465887   PMID:31724774   PMID:31924792   PMID:31942002   PMID:32259372   PMID:32296015   PMID:32319178  
PMID:32427396   PMID:32511952   PMID:32546759   PMID:32717817   PMID:32769099   PMID:32784053   PMID:32901292   PMID:32968282   PMID:32986815   PMID:33302058   PMID:33322598   PMID:33414188  
PMID:33454003   PMID:33460639   PMID:33711282   PMID:33723039   PMID:33892704   PMID:33899511   PMID:34061953   PMID:34093128   PMID:34383890   PMID:34508581   PMID:34576009   PMID:34615475  
PMID:35179492   PMID:35333176   PMID:35781329   PMID:35781558   PMID:35946435   PMID:36039295   PMID:36154671   PMID:36351424   PMID:36430853   PMID:36497119   PMID:36724256   PMID:36924502  
PMID:36941270  


Genomics

Comparative Map Data
Tfap2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391340,867,278 - 40,891,715 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1340,868,778 - 40,891,852 (-)EnsemblGRCm39 Ensembl
GRCm381340,713,802 - 40,738,238 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1340,715,302 - 40,738,376 (-)EnsemblGRCm38mm10GRCm38
MGSCv371340,811,044 - 40,829,192 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361340,727,706 - 40,745,894 (-)NCBIMGSCv36mm8
Celera1341,797,334 - 41,815,714 (-)NCBICelera
Cytogenetic Map13A3.3NCBI
cM Map1320.01NCBI
TFAP2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38610,396,677 - 10,419,659 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl610,393,186 - 10,419,659 (-)EnsemblGRCh38hg38GRCh38
GRCh37610,396,910 - 10,419,892 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36610,504,902 - 10,527,783 (-)NCBINCBI36Build 36hg18NCBI36
Build 34610,506,384 - 10,523,252NCBI
Celera611,625,394 - 11,648,276 (-)NCBICelera
Cytogenetic Map6p24.3NCBI
HuRef610,272,671 - 10,295,552 (-)NCBIHuRef
CHM1_1610,399,160 - 10,422,046 (-)NCBICHM1_1
T2T-CHM13v2.0610,264,407 - 10,287,386 (-)NCBIT2T-CHM13v2.0
Tfap2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21724,028,716 - 24,047,507 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1724,024,432 - 24,047,507 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1723,913,439 - 23,929,006 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01725,516,916 - 25,532,497 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01723,854,421 - 23,869,994 (+)NCBIRnor_WKY
Rnor_6.01724,653,342 - 24,670,457 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1724,654,902 - 24,670,457 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01726,596,839 - 26,634,214 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41730,017,580 - 30,034,852 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11730,020,346 - 30,035,192 (+)NCBI
Celera1723,700,225 - 23,715,767 (+)NCBICelera
Cytogenetic Map17p12NCBI
Tfap2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554653,882,549 - 3,898,929 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554653,877,896 - 3,900,259 (+)NCBIChiLan1.0ChiLan1.0
TFAP2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1621,036,711 - 21,053,926 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0610,237,834 - 10,260,843 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1610,519,625 - 10,541,898 (-)NCBIpanpan1.1PanPan1.1panPan2
TFAP2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13510,157,043 - 10,180,484 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3510,157,882 - 10,180,270 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3510,170,458 - 10,197,631 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03510,260,835 - 10,284,005 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3510,261,674 - 10,283,869 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13510,091,163 - 10,114,276 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03510,131,471 - 10,154,557 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03511,458,363 - 11,481,509 (-)NCBIUU_Cfam_GSD_1.0
Tfap2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494614,212,794 - 14,243,177 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365342,481,806 - 2,499,317 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365342,481,804 - 2,518,573 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFAP2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl77,221,656 - 7,244,612 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.177,221,654 - 7,244,626 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.277,534,956 - 7,556,586 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TFAP2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11761,750,757 - 61,769,041 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604410,406,413 - 10,425,011 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tfap2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475615,418,260 - 15,436,379 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475615,413,950 - 15,436,037 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tfap2a
876 total Variants
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir27bmmu-miR-27b-3pOncomiRDBexternal_infoNANA21922148

Predicted Target Of
Summary Value
Count of predictions:942
Count of miRNA genes:327
Interacting mature miRNAs:399
Transcripts:ENSMUST00000021787, ENSMUST00000110193
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
1558898Hpi1_mhapatic PMN infiltration 1 (mouse)Not determined13441402553101640Mouse
10402494Igmsc1_mimmunoglobulin M secreting cells 1 (mouse)Not determined131716854544918560Mouse
1301880Hypt_mhypertension (mouse)Not determined131815679252156924Mouse
13463469Gssq1_mglomerulosclerosis severity QTL 1 (mouse)131906090853061050Mouse
12880423V25Dq7_mvitamin D inactive form serum level QTL 7 (mouse)131958398353583983Mouse
1301015Sysbp2_msystolic blood pressure 2 (mouse)Not determined132047761259821605Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
1357591Tesq1_mtestis weight QTL 1 (mouse)Not determined132061551255720517Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
10045618Heal17_mwound healing/regeneration 17 (mouse)Not determined132074693954747056Mouse
4142489Ath25_matherosclerosis 25 (mouse)Not determined2583652959836529Mouse
10401111Pgia40_mproteoglycan induced arthritis 40 (mouse)Not determined132791846961918560Mouse
1300710Pcd4ts2_mp-glycoprotein positive CD4 T cell subset 2 (mouse)Not determined132821044262210544Mouse
1357802Vtbt15_mvertebral trabecular bone trait 15 (mouse)Not determined132821737962217515Mouse
10045621Heal21_mwound healing/regeneration 21 (mouse)Not determined132821737962217515Mouse
10755533Chol18_mcholesterol 18 (mouse)133096946764969467Mouse
10755517Chol15_mcholesterol 15 (mouse)133096946764969467Mouse
12738439Twq4_mtestis weight QTL 4 (mouse)133112911065129110Mouse
14696729Kidlq2_mkidney weight, left QTL 2 (mouse)133134473665344736Mouse
1301299Sluc23_msusceptibility to lung cancer 23 (mouse)Not determined133492194368922081Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133610153070101640Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133610153070101640Mouse
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133614482070144904Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133872035872720517Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133962924973629397Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133962924973629397Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133962924973629397Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse

Markers in Region
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
cM Map1325.0UniSTS
cM Map1325.0UniSTS
cM Map1325.0UniSTS
cM Map1325.0UniSTS
cM Map1325.0UniSTS
cM Map1325.0UniSTS
cM Map1325.0UniSTS
cM Map1320.01UniSTS
TFAP2A  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381340,730,331 - 40,730,648UniSTSGRCm38
MGSCv371340,825,700 - 40,826,017UniSTSGRCm37
Celera1341,811,992 - 41,812,309UniSTS
Cytogenetic Map13A5-B1UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
cM Map1325.0UniSTS
cM Map1320.01UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
cM Map1325.0UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
cM Map1325.0UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
cM Map1325.0UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
cM Map1325.0UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
cM Map1325.0UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
cM Map1325.0UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
Tcfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
Tfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
Tfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS
Tfap2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A5-B1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001122948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001301674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006516902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006516903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030247224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB221578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC123834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC159205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH003320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI195964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV233420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB543575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB652847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC007471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY731472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U17285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U17286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U17287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U17288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X57012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X74216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X95236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000021787   ⟹   ENSMUSP00000021787
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1340,868,778 - 40,883,919 (-)Ensembl
GRCm38.p6 Ensembl1340,715,302 - 40,730,443 (-)Ensembl
RefSeq Acc Id: ENSMUST00000110193   ⟹   ENSMUSP00000105822
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1340,869,151 - 40,887,299 (-)Ensembl
GRCm38.p6 Ensembl1340,715,675 - 40,733,823 (-)Ensembl
RefSeq Acc Id: ENSMUST00000223869   ⟹   ENSMUSP00000153149
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1340,870,081 - 40,891,852 (-)Ensembl
GRCm38.p6 Ensembl1340,716,605 - 40,738,376 (-)Ensembl
RefSeq Acc Id: ENSMUST00000223908
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1340,874,580 - 40,887,254 (-)Ensembl
GRCm38.p6 Ensembl1340,721,104 - 40,733,778 (-)Ensembl
RefSeq Acc Id: ENSMUST00000224319
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1340,869,498 - 40,885,083 (-)Ensembl
GRCm38.p6 Ensembl1340,716,022 - 40,731,607 (-)Ensembl
RefSeq Acc Id: ENSMUST00000224665   ⟹   ENSMUSP00000153667
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1340,870,208 - 40,887,451 (-)Ensembl
GRCm38.p6 Ensembl1340,716,732 - 40,733,975 (-)Ensembl
RefSeq Acc Id: ENSMUST00000224700
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1340,878,606 - 40,882,879 (-)Ensembl
GRCm38.p6 Ensembl1340,725,130 - 40,729,403 (-)Ensembl
RefSeq Acc Id: ENSMUST00000224999   ⟹   ENSMUSP00000153522
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1340,870,200 - 40,888,396 (-)Ensembl
GRCm38.p6 Ensembl1340,716,724 - 40,734,920 (-)Ensembl
RefSeq Acc Id: ENSMUST00000225180   ⟹   ENSMUSP00000153271
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1340,870,200 - 40,882,420 (-)Ensembl
GRCm38.p6 Ensembl1340,716,724 - 40,728,944 (-)Ensembl
RefSeq Acc Id: NM_001122948   ⟹   NP_001116420
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391340,868,779 - 40,883,933 (-)NCBI
GRCm381340,715,303 - 40,730,457 (-)NCBI
MGSCv371340,811,044 - 40,829,192 (-)RGD
Celera1341,796,962 - 41,816,812 (-)NCBI
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001301674   ⟹   NP_001288603
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391340,868,778 - 40,888,396 (-)NCBI
GRCm381340,715,302 - 40,734,920 (-)NCBI
Celera1341,796,962 - 41,816,812 (-)NCBI
Sequence:
RefSeq Acc Id: NM_011547   ⟹   NP_035677
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391340,868,778 - 40,887,271 (-)NCBI
GRCm381340,715,302 - 40,733,795 (-)NCBI
MGSCv371340,811,044 - 40,829,192 (-)RGD
Celera1341,796,962 - 41,816,812 (-)NCBI
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006516902   ⟹   XP_006516965
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391340,867,278 - 40,891,715 (-)NCBI
GRCm381340,713,802 - 40,738,238 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006516903   ⟹   XP_006516966
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391340,867,278 - 40,882,965 (-)NCBI
GRCm381340,713,802 - 40,729,478 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315479   ⟹   XP_017170968
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391340,867,278 - 40,882,684 (-)NCBI
GRCm381340,713,802 - 40,729,210 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030247224   ⟹   XP_030103084
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391340,868,778 - 40,884,970 (-)NCBI
GRCm381340,715,302 - 40,731,494 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001116420 (Get FASTA)   NCBI Sequence Viewer  
  NP_001288603 (Get FASTA)   NCBI Sequence Viewer  
  NP_035677 (Get FASTA)   NCBI Sequence Viewer  
  XP_006516965 (Get FASTA)   NCBI Sequence Viewer  
  XP_006516966 (Get FASTA)   NCBI Sequence Viewer  
  XP_017170968 (Get FASTA)   NCBI Sequence Viewer  
  XP_030103084 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA85677 (Get FASTA)   NCBI Sequence Viewer  
  AAA85678 (Get FASTA)   NCBI Sequence Viewer  
  AAA85679 (Get FASTA)   NCBI Sequence Viewer  
  AAA85680 (Get FASTA)   NCBI Sequence Viewer  
  AAA85681 (Get FASTA)   NCBI Sequence Viewer  
  AAA85682 (Get FASTA)   NCBI Sequence Viewer  
  AAA85683 (Get FASTA)   NCBI Sequence Viewer  
  AAA85684 (Get FASTA)   NCBI Sequence Viewer  
  AAH07471 (Get FASTA)   NCBI Sequence Viewer  
  AAH18226 (Get FASTA)   NCBI Sequence Viewer  
  BAB29047 (Get FASTA)   NCBI Sequence Viewer  
  BAC35484 (Get FASTA)   NCBI Sequence Viewer  
  BAE26642 (Get FASTA)   NCBI Sequence Viewer  
  CAA40331 (Get FASTA)   NCBI Sequence Viewer  
  CAA52292 (Get FASTA)   NCBI Sequence Viewer  
  CAA64523 (Get FASTA)   NCBI Sequence Viewer  
  EDL40950 (Get FASTA)   NCBI Sequence Viewer  
  EDL40951 (Get FASTA)   NCBI Sequence Viewer  
  EDL40952 (Get FASTA)   NCBI Sequence Viewer  
  EDL40953 (Get FASTA)   NCBI Sequence Viewer  
  EDL40954 (Get FASTA)   NCBI Sequence Viewer  
  EDL40955 (Get FASTA)   NCBI Sequence Viewer  
  P34056 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_035677   ⟸   NM_011547
- Peptide Label: isoform 1
- UniProtKB: A0A286YDR3 (UniProtKB/TrEMBL),   A0A6P5QYT8 (UniProtKB/TrEMBL),   A0A8C6MQE9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001116420   ⟸   NM_001122948
- Peptide Label: isoform 3
- UniProtKB: Q8BPN4 (UniProtKB/TrEMBL),   A0A6P5QPG8 (UniProtKB/TrEMBL),   A0A8C6GBP3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006516965   ⟸   XM_006516902
- Peptide Label: isoform X3
- UniProtKB: A0A286YCU0 (UniProtKB/TrEMBL),   A0A6P5QW94 (UniProtKB/TrEMBL),   A0A8C6GCG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006516966   ⟸   XM_006516903
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: NP_001288603   ⟸   NM_001301674
- Peptide Label: isoform 1
- UniProtKB: A0A286YDR3 (UniProtKB/TrEMBL),   A0A6P5QYT8 (UniProtKB/TrEMBL),   A0A8C6MQE9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017170968   ⟸   XM_017315479
- Peptide Label: isoform X2
- UniProtKB: A0A286YD43 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030103084   ⟸   XM_030247224
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000153149   ⟸   ENSMUST00000223869
RefSeq Acc Id: ENSMUSP00000105822   ⟸   ENSMUST00000110193
RefSeq Acc Id: ENSMUSP00000153271   ⟸   ENSMUST00000225180
RefSeq Acc Id: ENSMUSP00000153522   ⟸   ENSMUST00000224999
RefSeq Acc Id: ENSMUSP00000153667   ⟸   ENSMUST00000224665
RefSeq Acc Id: ENSMUSP00000021787   ⟸   ENSMUST00000021787
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P34056-F1-model_v2 AlphaFold P34056 1-437 view protein structure

Promoters
RGD ID:8680192
Promoter ID:EPDNEW_M18102
Type:multiple initiation site
Name:Tfap2a_3
Description:Mus musculus transcription factor AP-2, alpha , transcript variant1a, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18103  EPDNEW_M18104  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381340,730,427 - 40,730,487EPDNEW
RGD ID:8680144
Promoter ID:EPDNEW_M18103
Type:initiation region
Name:Tfap2a_2
Description:Mus musculus transcription factor AP-2, alpha , transcript variant1a, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18104  EPDNEW_M18102  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381340,731,004 - 40,731,064EPDNEW
RGD ID:8680146
Promoter ID:EPDNEW_M18104
Type:initiation region
Name:Tfap2a_1
Description:Mus musculus transcription factor AP-2, alpha , transcript variant1a, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18103  EPDNEW_M18102  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381340,733,793 - 40,733,853EPDNEW
RGD ID:6847082
Promoter ID:MM_ACW:12978
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0
Transcripts:TCFAP2A.KSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361340,813,776 - 40,814,276 (-)MPROMDB
RGD ID:6824440
Promoter ID:MM_KWN:13873
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0
Transcripts:UC007QED.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361340,820,191 - 40,820,691 (-)MPROMDB
RGD ID:6824444
Promoter ID:MM_KWN:13875
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   Kidney,   Lung
Transcripts:UC007QEI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361340,823,751 - 40,825,257 (-)MPROMDB
RGD ID:6824437
Promoter ID:MM_KWN:13876
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_2Hour,   Kidney,   Lung,   MEF_B4
Transcripts:NM_001122948
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361340,825,436 - 40,826,782 (-)MPROMDB
RGD ID:6824441
Promoter ID:MM_KWN:13877
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   Lung
Transcripts:UC007QEF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361340,826,846 - 40,827,697 (-)MPROMDB
RGD ID:6824436
Promoter ID:MM_KWN:13878
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   Kidney
Transcripts:ENSMUST00000110192,   NM_011547,   UC007QEJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361340,828,899 - 40,829,399 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104671 AgrOrtholog
Ensembl Genes ENSMUSG00000021359 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000021787 ENTREZGENE
  ENSMUSP00000021787.5 UniProtKB/TrEMBL
  ENSMUSP00000105822 ENTREZGENE
  ENSMUSP00000105822.3 UniProtKB/TrEMBL
  ENSMUSP00000153149 ENTREZGENE
  ENSMUSP00000153149.2 UniProtKB/TrEMBL
  ENSMUSP00000153271 ENTREZGENE
  ENSMUSP00000153271.2 UniProtKB/TrEMBL
  ENSMUSP00000153522 ENTREZGENE
  ENSMUSP00000153522.2 UniProtKB/TrEMBL
  ENSMUSP00000153667.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000021787 ENTREZGENE
  ENSMUST00000021787.7 UniProtKB/TrEMBL
  ENSMUST00000110193 ENTREZGENE
  ENSMUST00000110193.9 UniProtKB/TrEMBL
  ENSMUST00000223869 ENTREZGENE
  ENSMUST00000223869.2 UniProtKB/TrEMBL
  ENSMUST00000224665.2 UniProtKB/TrEMBL
  ENSMUST00000224999 ENTREZGENE
  ENSMUST00000224999.2 UniProtKB/TrEMBL
  ENSMUST00000225180 ENTREZGENE
  ENSMUST00000225180.2 UniProtKB/TrEMBL
InterPro TF_AP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_AP2_alpha_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_AP2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21418 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:104671 ENTREZGENE
NCBI Gene 21418 ENTREZGENE
PANTHER PTHR10812 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR AP-2-ALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TF_AP-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tfap2a PhenoGen
PRINTS AP2ATNSCPFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AP2TNSCPFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J1E6_MOUSE UniProtKB/TrEMBL
  A0A286YCU0 ENTREZGENE, UniProtKB/TrEMBL
  A0A286YD43 ENTREZGENE, UniProtKB/TrEMBL
  A0A286YDR3 ENTREZGENE, UniProtKB/TrEMBL
  A0A6P5QPG8 ENTREZGENE
  A0A6P5QW94 ENTREZGENE
  A0A6P5QYT8 ENTREZGENE
  A0A8C6GBP3 ENTREZGENE
  A0A8C6GCG3 ENTREZGENE
  A0A8C6MQE9 ENTREZGENE
  AP2A_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UL09_MOUSE UniProtKB/TrEMBL
  Q8BPN4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q60740 UniProtKB/Swiss-Prot
  Q60741 UniProtKB/Swiss-Prot
  Q60742 UniProtKB/Swiss-Prot
  Q60743 UniProtKB/Swiss-Prot
  Q62067 UniProtKB/Swiss-Prot
  Q62068 UniProtKB/Swiss-Prot
  Q62069 UniProtKB/Swiss-Prot
  Q91VX0 UniProtKB/Swiss-Prot
  Q9CRY4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-10-25 Tfap2a  transcription factor AP-2, alpha  Tcfap2a  transcription factor AP-2, alpha  Symbol and/or name change 5135510 APPROVED