MRPL21 (mitochondrial ribosomal protein L21) - Rat Genome Database

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Gene: MRPL21 (mitochondrial ribosomal protein L21) Homo sapiens
Analyze
Symbol: MRPL21
Name: mitochondrial ribosomal protein L21
RGD ID: 1320967
HGNC Page HGNC:14479
Description: Enables RNA binding activity. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 39S ribosomal protein L21, mitochondrial; bL21m; L21mt; large ribosomal subunit protein bL21m; MGC62013; mitochondrial large ribosomal subunit protein bL21m; MRP-L21
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381168,891,278 - 68,903,832 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1168,891,276 - 68,903,835 (-)EnsemblGRCh38hg38GRCh38
GRCh371168,658,746 - 68,671,300 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361168,415,322 - 68,427,879 (-)NCBINCBI36Build 36hg18NCBI36
Build 341168,415,322 - 68,427,879NCBI
Celera1165,998,605 - 66,010,817 (-)NCBICelera
Cytogenetic Map11q13.3NCBI
HuRef1164,997,532 - 65,010,064 (-)NCBIHuRef
CHM1_11168,542,411 - 68,554,742 (-)NCBICHM1_1
T2T-CHM13v2.01168,900,447 - 68,912,961 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11551941   PMID:11943462   PMID:12477932   PMID:12706105   PMID:14702039   PMID:15489334   PMID:17207965   PMID:20877624   PMID:21145461   PMID:21653829   PMID:21873635   PMID:22681889  
PMID:22904065   PMID:22939629   PMID:23473034   PMID:24981860   PMID:25278503   PMID:25609649   PMID:25900982   PMID:26186194   PMID:26406417   PMID:26496610   PMID:26725010   PMID:27023846  
PMID:27432908   PMID:27499296   PMID:27503909   PMID:27591049   PMID:28514442   PMID:28892042   PMID:29229926   PMID:29395067   PMID:29568061   PMID:29802200   PMID:31056398   PMID:31059266  
PMID:31091453   PMID:31617661   PMID:31722399   PMID:31871319   PMID:32628020   PMID:32694731   PMID:32877691   PMID:33545068   PMID:33957083   PMID:33961781   PMID:34079125   PMID:34800366  
PMID:35013218   PMID:35140242   PMID:35271311   PMID:35545034   PMID:35748872   PMID:35944360   PMID:36114006   PMID:36215168   PMID:37267103   PMID:37827155   PMID:38181584   PMID:38803224  


Genomics

Comparative Map Data
MRPL21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381168,891,278 - 68,903,832 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1168,891,276 - 68,903,835 (-)EnsemblGRCh38hg38GRCh38
GRCh371168,658,746 - 68,671,300 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361168,415,322 - 68,427,879 (-)NCBINCBI36Build 36hg18NCBI36
Build 341168,415,322 - 68,427,879NCBI
Celera1165,998,605 - 66,010,817 (-)NCBICelera
Cytogenetic Map11q13.3NCBI
HuRef1164,997,532 - 65,010,064 (-)NCBIHuRef
CHM1_11168,542,411 - 68,554,742 (-)NCBICHM1_1
T2T-CHM13v2.01168,900,447 - 68,912,961 (-)NCBIT2T-CHM13v2.0
Mrpl21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,332,997 - 3,342,837 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl193,332,901 - 3,342,837 (+)EnsemblGRCm39 Ensembl
GRCm38193,282,997 - 3,292,837 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,282,901 - 3,292,837 (+)EnsemblGRCm38mm10GRCm38
MGSCv37193,283,047 - 3,292,837 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36193,283,047 - 3,292,837 (+)NCBIMGSCv36mm8
Celera193,152,481 - 3,162,270 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map193.05NCBI
Mrpl21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81209,958,693 - 209,987,393 (+)NCBIGRCr8
mRatBN7.21200,529,416 - 200,542,568 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1200,529,416 - 200,537,896 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1208,902,768 - 208,911,245 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01215,991,356 - 215,999,834 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01208,665,564 - 208,674,042 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01218,532,045 - 218,545,428 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1218,532,045 - 218,540,523 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01225,399,844 - 225,412,818 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41205,815,335 - 205,823,813 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11205,968,951 - 205,977,263 (+)NCBI
Celera1198,084,305 - 198,092,783 (+)NCBICelera
Cytogenetic Map1q42NCBI
Mrpl21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542217,047,782 - 17,061,913 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542217,047,782 - 17,060,963 (+)NCBIChiLan1.0ChiLan1.0
MRPL21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21076,158,418 - 76,159,534 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11276,154,815 - 76,155,931 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01265,651,607 - 65,652,723 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11268,436,722 - 68,437,838 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1167,282,341 - 67,294,289 (-)Ensemblpanpan1.1panPan2
MRPL21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11849,090,521 - 49,104,052 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1849,090,689 - 49,104,051 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1847,697,942 - 47,711,118 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01849,896,022 - 49,909,219 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1849,740,644 - 50,014,473 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11849,224,951 - 49,236,886 (+)NCBIUMICH_Zoey_3.1
UU_Cfam_GSD_1.01849,544,129 - 49,557,318 (+)NCBIUU_Cfam_GSD_1.0
Mrpl21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049474,997,858 - 5,006,075 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365991,440,156 - 1,448,472 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365991,440,207 - 1,448,424 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRPL21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.115,655,043 - 5,667,452 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl15,654,387 - 5,669,290 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038102,933,478 - 102,945,899 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in MRPL21
19 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q13.2-13.3(chr11:67217264-69448598)x1 copy number loss See cases [RCV000135609] Chr11:67217264..69448598 [GRCh38]
Chr11:66984735..69263366 [GRCh37]
Chr11:66741311..68972547 [NCBI36]
Chr11:11q13.2-13.3		 likely pathogenic
GRCh38/hg38 11q13.2-13.3(chr11:68205963-69580475)x3 copy number gain See cases [RCV000137992] Chr11:68205963..69580475 [GRCh38]
Chr11:67973430..69395243 [GRCh37]
Chr11:67730006..69104424 [NCBI36]
Chr11:11q13.2-13.3		 likely benign
GRCh38/hg38 11q13.2-13.4(chr11:68031693-71593495)x1 copy number loss See cases [RCV000142138] Chr11:68031693..71593495 [GRCh38]
Chr11:67799160..71304541 [GRCh37]
Chr11:67555736..70982189 [NCBI36]
Chr11:11q13.2-13.4		 likely pathogenic
NC_000011.10:g.68903737G>A single nucleotide variant not provided [RCV001566323] Chr11:68903737 [GRCh38]
Chr11:68671205 [GRCh37]
Chr11:11q13.3		 likely benign
GRCh37/hg19 11q13.2-13.4(chr11:67799160-70701268)x1 copy number loss See cases [RCV000510219] Chr11:67799160..70701268 [GRCh37]
Chr11:11q13.2-13.4		 likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
NM_181514.2(MRPL21):c.581G>A (p.Arg194Gln) single nucleotide variant not specified [RCV004285917] Chr11:68891368 [GRCh38]
Chr11:68658836 [GRCh37]
Chr11:11q13.3		 uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
NM_181514.2(MRPL21):c.245A>T (p.Lys82Met) single nucleotide variant not specified [RCV004300115] Chr11:68896666 [GRCh38]
Chr11:68664134 [GRCh37]
Chr11:11q13.3		 uncertain significance
NM_002180.2(IGHMBP2):c.-317A>G single nucleotide variant not provided [RCV000827871] Chr11:68903636 [GRCh38]
Chr11:68671104 [GRCh37]
Chr11:11q13.3		 benign
NM_181514.2(MRPL21):c.584T>G (p.Ile195Arg) single nucleotide variant not specified [RCV004298532] Chr11:68891365 [GRCh38]
Chr11:68658833 [GRCh37]
Chr11:11q13.3		 uncertain significance
NC_000011.9:g.(?_64973914)_(70052579_?)dup duplication Aicardi-Goutieres syndrome 3 [RCV003113322]|FADD-related immunodeficiency [RCV003107753] Chr11:64973914..70052579 [GRCh37]
Chr11:11q13.1-13.3		 uncertain significance
NC_000011.10:g.68903809A>G single nucleotide variant not provided [RCV001677017] Chr11:68903809 [GRCh38]
Chr11:68671277 [GRCh37]
Chr11:11q13.3		 benign
NC_000011.10:g.68903633A>G single nucleotide variant not provided [RCV001539638] Chr11:68903633 [GRCh38]
Chr11:68671101 [GRCh37]
Chr11:11q13.3		 likely benign
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3		 pathogenic
NC_000011.9:g.(?_59596957)_(68707199_?)dup duplication Familial temporal lobe epilepsy 8 [RCV001372442] Chr11:59596957..68707199 [GRCh37]
Chr11:11q12.1-13.3		 uncertain significance
NC_000011.10:g.68903813_68903816CCG[2]CCATCTTCCCGC[1] microsatellite not provided [RCV001654025] Chr11:68903812..68903813 [GRCh38]
Chr11:68671280..68671281 [GRCh37]
Chr11:11q13.3		 benign
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25		 pathogenic
NM_181514.2(MRPL21):c.125A>G (p.Gln42Arg) single nucleotide variant not specified [RCV004235704] Chr11:68900569 [GRCh38]
Chr11:68668037 [GRCh37]
Chr11:11q13.3		 uncertain significance
NM_181514.2(MRPL21):c.149A>G (p.Tyr50Cys) single nucleotide variant not specified [RCV004100527] Chr11:68898010 [GRCh38]
Chr11:68665478 [GRCh37]
Chr11:11q13.3		 uncertain significance
NM_181514.2(MRPL21):c.223C>G (p.His75Asp) single nucleotide variant not specified [RCV004122749] Chr11:68897936 [GRCh38]
Chr11:68665404 [GRCh37]
Chr11:11q13.3		 uncertain significance
NM_181514.2(MRPL21):c.386G>A (p.Arg129Gln) single nucleotide variant not specified [RCV004083300] Chr11:68896525 [GRCh38]
Chr11:68663993 [GRCh37]
Chr11:11q13.3		 uncertain significance
NM_181514.2(MRPL21):c.175C>T (p.Pro59Ser) single nucleotide variant not specified [RCV004131756] Chr11:68897984 [GRCh38]
Chr11:68665452 [GRCh37]
Chr11:11q13.3		 uncertain significance
NM_181514.2(MRPL21):c.205C>G (p.Pro69Ala) single nucleotide variant not specified [RCV004261080] Chr11:68897954 [GRCh38]
Chr11:68665422 [GRCh37]
Chr11:11q13.3		 uncertain significance
NM_181514.2(MRPL21):c.368C>T (p.Ala123Val) single nucleotide variant not specified [RCV004252816] Chr11:68896543 [GRCh38]
Chr11:68664011 [GRCh37]
Chr11:11q13.3		 uncertain significance
NM_181514.2(MRPL21):c.112A>G (p.Arg38Gly) single nucleotide variant not specified [RCV004357911] Chr11:68900582 [GRCh38]
Chr11:68668050 [GRCh37]
Chr11:11q13.3		 uncertain significance
GRCh37/hg19 11q12.2-13.5(chr11:59923608-76272324)x3 copy number gain not provided [RCV003484842] Chr11:59923608..76272324 [GRCh37]
Chr11:11q12.2-13.5		 pathogenic
GRCh37/hg19 11q12.1-13.3(chr11:56895955-69295402)x3 copy number gain not specified [RCV003986944] Chr11:56895955..69295402 [GRCh37]
Chr11:11q12.1-13.3		 likely pathogenic
NM_181514.2(MRPL21):c.137A>G (p.Tyr46Cys) single nucleotide variant not specified [RCV004504498] Chr11:68900557 [GRCh38]
Chr11:68668025 [GRCh37]
Chr11:11q13.3		 uncertain significance
NM_181514.2(MRPL21):c.216G>T (p.Glu72Asp) single nucleotide variant not specified [RCV004504509] Chr11:68897943 [GRCh38]
Chr11:68665411 [GRCh37]
Chr11:11q13.3		 uncertain significance
NM_181514.2(MRPL21):c.50G>C (p.Cys17Ser) single nucleotide variant not specified [RCV004631645] Chr11:68903761 [GRCh38]
Chr11:68671229 [GRCh37]
Chr11:11q13.3		 uncertain significance
NM_181514.2(MRPL21):c.79C>T (p.Pro27Ser) single nucleotide variant not specified [RCV004638157] Chr11:68903732 [GRCh38]
Chr11:68671200 [GRCh37]
Chr11:11q13.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2484
Count of miRNA genes:788
Interacting mature miRNAs:925
Transcripts:ENST00000362034, ENST00000450904, ENST00000536637, ENST00000541265, ENST00000541279, ENST00000544567, ENST00000565125, ENST00000567045
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357380BW64_HBody weight QTL 64 (human)2.2Body weightpercent fat after exercise training116097893786978937Human
596961389GWAS1080908_Hmetabolic syndrome QTL GWAS1080908 (human)1e-09metabolic syndrome116889202068892021Human
597018217GWAS1114291_Hmetabolic syndrome QTL GWAS1114291 (human)1e-09metabolic syndrome116889202068892021Human

Markers in Region
RH15743  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371168,658,798 - 68,660,428UniSTSGRCh37
Celera1165,998,657 - 65,999,928UniSTS
Cytogenetic Map11q13.3UniSTS
HuRef1164,997,584 - 64,999,176UniSTS
GeneMap99-GB4 RH Map12288.48UniSTS
NCBI RH Map12507.5UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1951 465 2270 7306 6472 53 3734 1 852 1744 1617 175 1

Sequence


Ensembl Acc Id: ENST00000362034   ⟹   ENSP00000354580
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1168,891,278 - 68,903,832 (-)Ensembl
Ensembl Acc Id: ENST00000450904   ⟹   ENSP00000389400
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1168,891,276 - 68,903,786 (-)Ensembl
Ensembl Acc Id: ENST00000536637
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1168,897,594 - 68,903,802 (-)Ensembl
Ensembl Acc Id: ENST00000541265   ⟹   ENSP00000445009
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1168,892,969 - 68,903,832 (-)Ensembl
Ensembl Acc Id: ENST00000541279   ⟹   ENSP00000442243
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1168,891,283 - 68,903,827 (-)Ensembl
Ensembl Acc Id: ENST00000544567   ⟹   ENSP00000438837
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1168,892,895 - 68,903,814 (-)Ensembl
Ensembl Acc Id: ENST00000565125   ⟹   ENSP00000456520
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1168,891,279 - 68,903,835 (-)Ensembl
Ensembl Acc Id: ENST00000567045   ⟹   ENSP00000457859
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1168,892,492 - 68,903,778 (-)Ensembl
RefSeq Acc Id: NM_181514   ⟹   NP_852615
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381168,891,278 - 68,903,832 (-)NCBI
GRCh371168,658,744 - 68,671,303 (-)NCBI
Build 361168,415,322 - 68,427,879 (-)NCBI Archive
Celera1165,998,605 - 66,010,817 (-)RGD
HuRef1164,997,532 - 65,010,064 (-)ENTREZGENE
CHM1_11168,542,411 - 68,554,742 (-)NCBI
T2T-CHM13v2.01168,900,447 - 68,912,961 (-)NCBI
Sequence:
RefSeq Acc Id: NM_181515   ⟹   NP_852616
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381168,891,278 - 68,903,832 (-)NCBI
GRCh371168,658,744 - 68,671,303 (-)NCBI
Build 361168,415,322 - 68,427,879 (-)NCBI Archive
Celera1165,998,605 - 66,010,817 (-)RGD
HuRef1164,997,532 - 65,010,064 (-)ENTREZGENE
CHM1_11168,542,411 - 68,554,742 (-)NCBI
T2T-CHM13v2.01168,900,447 - 68,912,961 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005273823   ⟹   XP_005273880
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381168,891,308 - 68,903,832 (-)NCBI
GRCh371168,658,744 - 68,671,303 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054367991   ⟹   XP_054223966
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01168,900,588 - 68,912,961 (-)NCBI
RefSeq Acc Id: XR_008488360
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01168,902,031 - 68,912,961 (-)NCBI
RefSeq Acc Id: XR_247190
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381168,892,898 - 68,903,832 (-)NCBI
GRCh371168,658,744 - 68,671,303 (-)NCBI
Sequence:
RefSeq Acc Id: NP_852615   ⟸   NM_181514
- Peptide Label: isoform d
- UniProtKB: Q7Z2W9 (UniProtKB/Swiss-Prot),   C9JPR2 (UniProtKB/Swiss-Prot),   A6NKU0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_852616   ⟸   NM_181515
- Peptide Label: isoform a
- Sequence:
RefSeq Acc Id: XP_005273880   ⟸   XM_005273823
- Peptide Label: isoform X1
- UniProtKB: B4DXI4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000445009   ⟸   ENST00000541265
Ensembl Acc Id: ENSP00000442243   ⟸   ENST00000541279
Ensembl Acc Id: ENSP00000389400   ⟸   ENST00000450904
Ensembl Acc Id: ENSP00000438837   ⟸   ENST00000544567
Ensembl Acc Id: ENSP00000354580   ⟸   ENST00000362034
Ensembl Acc Id: ENSP00000456520   ⟸   ENST00000565125
Ensembl Acc Id: ENSP00000457859   ⟸   ENST00000567045
RefSeq Acc Id: XP_054223966   ⟸   XM_054367991
- Peptide Label: isoform X1
- UniProtKB: B4DXI4 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7Z2W9-F1-model_v2 AlphaFold Q7Z2W9 1-205 view protein structure

Promoters
RGD ID:6789006
Promoter ID:HG_KWN:13529
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_002180,   NM_181514,   NM_181515,   UC001OOJ.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361168,427,674 - 68,428,174 (+)MPROMDB
RGD ID:7221337
Promoter ID:EPDNEW_H16414
Type:initiation region
Name:MRPL21_1
Description:mitochondrial ribosomal protein L21
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381168,903,832 - 68,903,892EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:14479 AgrOrtholog
COSMIC MRPL21 COSMIC
Ensembl Genes ENSG00000197345 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000362034 ENTREZGENE
  ENST00000362034.7 UniProtKB/Swiss-Prot
  ENST00000450904 ENTREZGENE
  ENST00000450904.6 UniProtKB/Swiss-Prot
  ENST00000541265.1 UniProtKB/TrEMBL
  ENST00000541279 ENTREZGENE
  ENST00000541279.1 UniProtKB/TrEMBL
  ENST00000544567.5 UniProtKB/TrEMBL
  ENST00000565125.5 UniProtKB/TrEMBL
  ENST00000567045.5 UniProtKB/TrEMBL
GTEx ENSG00000197345 GTEx
HGNC ID HGNC:14479 ENTREZGENE
Human Proteome Map MRPL21 Human Proteome Map
InterPro L21-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  L21p-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_L21 UniProtKB/Swiss-Prot
KEGG Report hsa:219927 UniProtKB/Swiss-Prot
NCBI Gene MRPL21 ENTREZGENE
OMIM 611834 OMIM
PANTHER 39S RIBOSOMAL PROTEIN L21, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR21349 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ribosomal_L21p UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA30951 PharmGKB
Superfamily-SCOP SSF141091 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6NKU0 ENTREZGENE
  B4DXI4 ENTREZGENE, UniProtKB/TrEMBL
  C9JPR2 ENTREZGENE
  F5H3L0_HUMAN UniProtKB/TrEMBL
  F5H4R5_HUMAN UniProtKB/TrEMBL
  F5H7V8_HUMAN UniProtKB/TrEMBL
  H3BUY0_HUMAN UniProtKB/TrEMBL
  Q7Z2W9 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A6NKU0 UniProtKB/Swiss-Prot
  C9JPR2 UniProtKB/Swiss-Prot