Atp6v1g1 (ATPase, H+ transporting, lysosomal V1 subunit G1) - Rat Genome Database

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Gene: Atp6v1g1 (ATPase, H+ transporting, lysosomal V1 subunit G1) Mus musculus
Analyze
Symbol: Atp6v1g1
Name: ATPase, H+ transporting, lysosomal V1 subunit G1
RGD ID: 1320794
MGI Page MGI
Description: Enables ATP hydrolysis activity and proton-transporting ATPase activity, rotational mechanism. Involved in synaptic vesicle lumen acidification. Located in cytosol; lysosomal membrane; and plasma membrane. Part of proton-transporting V-type ATPase, V1 domain and vacuolar proton-transporting V-type ATPase complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human ATP6V1G1 (ATPase H+ transporting V1 subunit G1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1810024D14Rik; AA960677; ATP; Atp6; Atp6g1; ATP6J; ATPase, H+ transporting, lysosomal (vacuolar proton pump); ATPase, H+ transporting, lysosomal 13kD, V1 subunit G; ATPase, H+ transporting, V1 subunit G; lysosomal 13kDa; V-ATPase 13 kDa subunit 1; V-ATPase subunit G 1; V-type proton ATPase subunit G 1; VA; vacuolar proton pump subunit G 1; VAG1; Vma; Vma10
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm12344   Gm13453   Gm17812   Gm17813   Gm2517   Gm5283   Gm6308   Gm7898  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39463,463,002 - 63,468,938 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl463,463,009 - 63,468,987 (+)EnsemblGRCm39 Ensembl
GRCm38463,544,765 - 63,550,701 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl463,544,772 - 63,550,750 (+)EnsemblGRCm38mm10GRCm38
MGSCv37463,205,799 - 63,211,735 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36463,031,198 - 63,037,062 (+)NCBIMGSCv36mm8
Celera462,204,906 - 62,210,851 (+)NCBICelera
Cytogenetic Map4B3NCBI
cM Map434.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunits. Sun-Wada GH, etal., Gene 2003 Jan 2;302(1-2):147-53.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11812828   PMID:12133826   PMID:12477932   PMID:14610273   PMID:14681479   PMID:15489334   PMID:15782199  
PMID:16141072   PMID:16141073   PMID:16177003   PMID:21267068   PMID:21677750   PMID:21873635   PMID:26442671   PMID:27085457   PMID:28793259   PMID:30418981   PMID:30595499   PMID:30713523  
PMID:32325033   PMID:32513711   PMID:36417873   PMID:38702933  


Genomics

Comparative Map Data
Atp6v1g1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39463,463,002 - 63,468,938 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl463,463,009 - 63,468,987 (+)EnsemblGRCm39 Ensembl
GRCm38463,544,765 - 63,550,701 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl463,544,772 - 63,550,750 (+)EnsemblGRCm38mm10GRCm38
MGSCv37463,205,799 - 63,211,735 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36463,031,198 - 63,037,062 (+)NCBIMGSCv36mm8
Celera462,204,906 - 62,210,851 (+)NCBICelera
Cytogenetic Map4B3NCBI
cM Map434.01NCBI
ATP6V1G1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389114,587,769 - 114,598,879 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9114,587,706 - 114,598,915 (+)EnsemblGRCh38hg38GRCh38
GRCh379117,350,049 - 117,361,159 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369116,389,815 - 116,400,973 (+)NCBINCBI36Build 36hg18NCBI36
Build 349114,429,579 - 114,440,206NCBI
Celera987,997,647 - 88,008,806 (+)NCBICelera
Cytogenetic Map9q32NCBI
HuRef986,955,148 - 86,966,307 (+)NCBIHuRef
CHM1_19117,496,680 - 117,507,848 (+)NCBICHM1_1
T2T-CHM13v2.09126,780,187 - 126,791,297 (+)NCBIT2T-CHM13v2.0
Atp6v1g1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8581,976,959 - 81,983,139 (+)NCBIGRCr8
mRatBN7.2576,961,462 - 76,967,642 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl576,961,499 - 76,969,463 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx579,360,978 - 79,367,187 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0581,178,134 - 81,184,345 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0581,153,632 - 81,159,843 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0579,367,663 - 79,373,843 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl579,367,663 - 79,373,843 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0583,481,867 - 83,488,047 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4580,515,635 - 80,521,815 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1580,520,811 - 80,526,974 (+)NCBI
Celera575,895,498 - 75,901,678 (+)NCBICelera
Cytogenetic Map5q24NCBI
Atp6v1g1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541913,047,755 - 13,056,221 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541913,047,755 - 13,056,113 (-)NCBIChiLan1.0ChiLan1.0
ATP6V1G1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21124,779,040 - 24,790,744 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1924,781,400 - 24,792,708 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0985,685,910 - 85,696,255 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19114,048,387 - 114,058,878 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9114,048,387 - 114,058,878 (+)Ensemblpanpan1.1panPan2
ATP6V1G1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11168,755,586 - 68,760,863 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1167,153,026 - 67,162,490 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01169,874,857 - 69,884,359 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1169,741,009 - 69,882,907 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11168,389,934 - 68,399,413 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01168,430,341 - 68,439,666 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01169,161,079 - 69,170,540 (+)NCBIUU_Cfam_GSD_1.0
Atp6v1g1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947184,033,200 - 184,041,470 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364873,801,665 - 3,811,293 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364873,801,745 - 3,809,997 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC102165256
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1719,272,032 - 19,272,926 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2720,421,533 - 20,423,014 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATP6V1G1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11224,994,480 - 25,004,618 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1224,994,051 - 25,004,668 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603517,826,004 - 17,836,791 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp6v1g1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476020,624,624 - 20,636,631 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476020,627,985 - 20,636,670 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atp6v1g1
337 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:546
Count of miRNA genes:345
Interacting mature miRNAs:382
Transcripts:ENSMUST00000035301
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25394561Skmw53_mskeletal muscle weight 53, TA (mouse)46213829369838031Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123127211Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
25314308Mlh1fc1_mMLH1 foci count 1 (mouse)44850000076918237Mouse
26884434Zlq1_mzygomatic length QTL 1, 5 week (mouse)453700000103257197Mouse
1301786Bpq3_mblood pressure QTL 3 (mouse)Not determined44240224076402381Mouse
1301213Lgth3_mbody length 3 (mouse)Not determined45010026284100408Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
1301190Cd4ts2_mCD4 T cell subset 2 (mouse)Not determined46014527794145424Mouse
1357507Synch2_msynechia 2 (mouse)Not determined46014527794145424Mouse
1357443Lhyp_mlung hyperpermeability (mouse)Not determined46045401166764818Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse
13207572Spir2_mStreptococcus pneumoniae infection resistance 2 (mouse)45068279588510637Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
10449022Aanq1_maristolochic acid nephrotoxicity QTL 1 (mouse)44660382680603826Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
27095934Ulnl2_mulna length 2, 5 week (mouse)45770000094788237Mouse
10043964Obq26_mobesity QTL 26 (mouse)Not determined45904725193047251Mouse
1301941Mmtg1_mmodifier of mammary tumor growth 1 (mouse)Not determined44565844283099157Mouse
13524841Hbasrq1_mhabituation of the acoustic startle response QTL 1 (mouse)45447158988471589Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
13524838Hbasrq1a_mhabituation of the acoustic startle response QTL 1a (mouse)45447158988471589Mouse
12879977Bod2_mbone length and organs 2 (mouse)44628353180283678Mouse
10043880Adip23_madiposity 23 (mouse)Not determined44628353180283678Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1558948Ath8_matherosclerosis 8 (mouse)Not determined445658442105156995Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124055180Mouse
1300966Pabr2_mplasma apolipoprotein B (human) regulator 2 (mouse)Not determined446332646105801860Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
1301995Lprm1_mlymphoproliferation modifier 1 (mouse)Not determined45010026284100408Mouse
1301033Abbp2_mA/J and C57BL/6 blood pressure 2 (mouse)Not determined45355083993763305Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
27226724Tibw2_mtibia width 2, proximal, 10 week (mouse)443000000108357197Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000128993793Mouse
11532688Mh_mmodifier of hemostasis (mouse)44830477582304775Mouse

Markers in Region
AA960677  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Whitehead/MRC_RH2634.61UniSTS
RH125303  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C1UniSTS
Atp6v1g1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38463,548,600 - 63,550,006UniSTSGRCm38
GRCm38240,127,616 - 40,127,763UniSTSGRCm38
MGSCv37463,209,634 - 63,211,040UniSTSGRCm37
MGSCv37239,983,136 - 39,983,283UniSTSGRCm37
Celera462,208,745 - 62,210,155UniSTS
Celera241,849,086 - 41,849,233UniSTS
Cytogenetic Map4C1UniSTS
Cytogenetic Map2BUniSTS
cM Map4 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_024173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB076406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI836426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK007596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL691484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC088836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN838691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000035301   ⟹   ENSMUSP00000048770
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl463,463,009 - 63,468,987 (+)Ensembl
GRCm38.p6 Ensembl463,544,772 - 63,550,750 (+)Ensembl
RefSeq Acc Id: NM_024173   ⟹   NP_077135
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39463,463,002 - 63,468,938 (+)NCBI
GRCm38463,544,765 - 63,550,701 (+)ENTREZGENE
MGSCv37463,205,799 - 63,211,735 (+)RGD
Celera462,204,906 - 62,210,851 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_077135   ⟸   NM_024173
- UniProtKB: Q9CR51 (UniProtKB/Swiss-Prot),   Q3U7E0 (UniProtKB/TrEMBL),   Q5HZY7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000048770   ⟸   ENSMUST00000035301

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CR51-F1-model_v2 AlphaFold Q9CR51 1-118 view protein structure

Promoters
RGD ID:6834921
Promoter ID:MM_KWN:38007
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_024173_ATP6V1G1,   OTTMUST00000000798
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36463,205,749 - 63,206,249 (+)MPROMDB
RGD ID:6883652
Promoter ID:EPDNEW_M5277
Type:initiation region
Name:Atp6v1g1_1
Description:Mus musculus ATPase, H+ transporting, lysosomal V1 subunit G1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38463,544,842 - 63,544,902EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913540 AgrOrtholog
Ensembl Genes ENSMUSG00000039105 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000035301 ENTREZGENE
  ENSMUST00000035301.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.2950 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro V-ATPase_G UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:66290 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1913540 ENTREZGENE
NCBI Gene 66290 ENTREZGENE
PANTHER PTHR12713 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V-TYPE PROTON ATPASE SUBUNIT G 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam V-ATPase_G UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Atp6v1g1 PhenoGen
UniProt Q3U7E0 ENTREZGENE, UniProtKB/TrEMBL
  Q5HZY7 ENTREZGENE, UniProtKB/TrEMBL
  Q9CR51 ENTREZGENE, UniProtKB/Swiss-Prot