Cr2 (complement receptor 2) - Rat Genome Database

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Gene: Cr2 (complement receptor 2) Mus musculus
Analyze
Symbol: Cr2
Name: complement receptor 2
RGD ID: 1320754
MGI Page MGI
Description: Enables complement receptor activity. Acts upstream of or within with a negative effect on complement activation, alternative pathway. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; immunoglobulin mediated immune response; and skeletal system development. Located in external side of plasma membrane. Is expressed in several structures, including brain; hemolymphoid system; liver; placenta; and yolk sac. Human ortholog(s) of this gene implicated in common variable immunodeficiency 7; nasopharynx carcinoma; and systemic lupus erythematosus. Orthologous to human CR2 (complement C3d receptor 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C3D; C3DR; CD21; CD35; complement C3d receptor; complement receptor type 1; complement receptor type 2; Cr; Cr-; Cr-1; Cr-2; Cr1; expressed in B lymphocytes; MGC130295
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391194,819,120 - 194,859,096 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1194,819,119 - 194,859,024 (-)EnsemblGRCm39 Ensembl
GRCm381195,136,811 - 195,176,880 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1195,136,811 - 195,176,716 (-)EnsemblGRCm38mm10GRCm38
MGSCv371196,963,005 - 197,002,909 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361196,840,394 - 196,877,439 (-)NCBIMGSCv36mm8
Celera1202,035,969 - 202,075,750 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map198.44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional polymorphism in the 5'-UTR of CR2 is associated with susceptibility to nasopharyngeal carcinoma. Fan Q, etal., Oncol Rep. 2013 Jul;30(1):11-6. doi: 10.3892/or.2013.2421. Epub 2013 Apr 23.
2. Complement and natural antibody are required in the long-term memory response to influenza virus. Fernandez Gonzalez S, etal., Vaccine. 2008 Dec 30;26 Suppl 8:I86-93. doi: 10.1016/j.vaccine.2008.11.057.
3. Relative Impact of Complement Receptors CD21/35 (Cr2/1) on Scrapie Pathogenesis in Mice. Kane SJ, etal., mSphere. 2017 Nov 22;2(6). pii: mSphere00493-17. doi: 10.1128/mSphereDirect.00493-17. eCollection 2017 Nov-Dec.
4. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
5. Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response. Lindblom RP, etal., J Neuroinflammation. 2015 Oct 26;12:192. doi: 10.1186/s12974-015-0413-6.
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Molecular cloning of rat and mouse membrane cofactor protein (MCP, CD46): preferential expression in testis and close linkage between the mouse Mcp and Cr2 genes on distal chromosome 1. Miwa T, etal., Immunogenetics 1998 Nov-Dec;48(6):363-71.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. In vivo decrease in the expression of complement receptor 2 on B-cells in HIV infection. Scott ME, etal., AIDS. 1993 Jan;7(1):37-41. doi: 10.1097/00002030-199301000-00006.
15. Mouse complement receptors type 1 (CR1;CD35) and type 2 (CR2;CD21): expression on normal B cell subpopulations and decreased levels during the development of autoimmunity in MRL/lpr mice. Takahashi K, etal., J Immunol. 1997 Aug 1;159(3):1557-69.
Additional References at PubMed
PMID:1358803   PMID:1431091   PMID:1534100   PMID:1543915   PMID:2139457   PMID:2139460   PMID:2145366   PMID:2528587   PMID:2564419   PMID:2783485   PMID:2966205   PMID:6363792  
PMID:7528766   PMID:7693486   PMID:8001974   PMID:8041705   PMID:8138038   PMID:8144890   PMID:8509145   PMID:8622941   PMID:8624815   PMID:9021164   PMID:9144490   PMID:9278336  
PMID:9314499   PMID:9323135   PMID:9396768   PMID:9794381   PMID:9846493   PMID:10349636   PMID:10477568   PMID:10497278   PMID:10523614   PMID:10779753   PMID:10946257   PMID:10946263  
PMID:10975825   PMID:11042159   PMID:11067882   PMID:11076861   PMID:11120817   PMID:11283678   PMID:11371362   PMID:11423567   PMID:11435465   PMID:11477411   PMID:11544305   PMID:11728339  
PMID:11739537   PMID:11857338   PMID:11869678   PMID:11907091   PMID:11927943   PMID:12008031   PMID:12067757   PMID:12121667   PMID:12133988   PMID:12165541   PMID:12244142   PMID:12417629  
PMID:12421918   PMID:12421939   PMID:12466851   PMID:12477932   PMID:12479818   PMID:12496386   PMID:12517942   PMID:12732659   PMID:12925675   PMID:14662849   PMID:14743001   PMID:15004151  
PMID:15128761   PMID:15186779   PMID:15192652   PMID:15477230   PMID:15505215   PMID:15585877   PMID:15693014   PMID:15749857   PMID:15767369   PMID:15804286   PMID:15808537   PMID:15905540  
PMID:15909309   PMID:15919902   PMID:16002709   PMID:16082726   PMID:16116172   PMID:16127466   PMID:16141072   PMID:16141073   PMID:16210644   PMID:16322460   PMID:16339538   PMID:16413924  
PMID:16517720   PMID:16733062   PMID:16781728   PMID:16880262   PMID:16893077   PMID:16906534   PMID:16920928   PMID:16943797   PMID:17023586   PMID:17082645   PMID:17140663   PMID:17283093  
PMID:17446933   PMID:17513746   PMID:17579038   PMID:17660822   PMID:17892214   PMID:17947689   PMID:18037889   PMID:18059271   PMID:18180309   PMID:18243341   PMID:18295335   PMID:18354231  
PMID:18374982   PMID:18713965   PMID:19017934   PMID:19060331   PMID:19185517   PMID:19201479   PMID:19359041   PMID:19380783   PMID:19414760   PMID:19494269   PMID:19503106   PMID:19630912  
PMID:19706534   PMID:19710450   PMID:19710459   PMID:19740539   PMID:19815275   PMID:19828624   PMID:19965666   PMID:20439480   PMID:20962256   PMID:21187447   PMID:21267068   PMID:21411641  
PMID:21873635   PMID:21987785   PMID:22000720   PMID:22427639   PMID:22566568   PMID:22848677   PMID:23002439   PMID:23263181   PMID:23382219   PMID:23440418   PMID:23601687   PMID:23733878  
PMID:23770227   PMID:24012440   PMID:24129162   PMID:24636730   PMID:24885042   PMID:25457881   PMID:26619292   PMID:27644882   PMID:28710441   PMID:29581196   PMID:30217731   PMID:30573546  
PMID:30636035   PMID:30988302   PMID:32142650   PMID:32424104   PMID:32907542   PMID:33707780   PMID:33912182   PMID:34031614   PMID:34249009   PMID:35021101   PMID:35143312   PMID:35358427  
PMID:36454023   PMID:39226900  


Genomics

Comparative Map Data
Cr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391194,819,120 - 194,859,096 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1194,819,119 - 194,859,024 (-)EnsemblGRCm39 Ensembl
GRCm381195,136,811 - 195,176,880 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1195,136,811 - 195,176,716 (-)EnsemblGRCm38mm10GRCm38
MGSCv371196,963,005 - 197,002,909 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361196,840,394 - 196,877,439 (-)NCBIMGSCv36mm8
Celera1202,035,969 - 202,075,750 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map198.44NCBI
CR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381207,454,328 - 207,489,892 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1207,453,024 - 207,489,895 (+)EnsemblGRCh38hg38GRCh38
GRCh371207,627,673 - 207,663,237 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361205,694,293 - 205,729,863 (+)NCBINCBI36Build 36hg18NCBI36
Build 341204,016,064 - 204,051,633NCBI
Celera1180,876,666 - 180,912,267 (+)NCBICelera
Cytogenetic Map1q32.2NCBI
HuRef1178,320,710 - 178,356,313 (+)NCBIHuRef
CHM1_11208,900,385 - 208,935,976 (+)NCBICHM1_1
T2T-CHM13v2.01206,719,629 - 206,755,209 (+)NCBIT2T-CHM13v2.0
Cr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813109,207,034 - 109,244,980 (-)NCBIGRCr8
mRatBN7.213106,678,579 - 106,716,595 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13106,685,413 - 106,716,235 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13109,202,762 - 109,233,397 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013110,586,602 - 110,617,233 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013107,811,075 - 107,841,707 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013113,890,274 - 113,927,824 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13113,890,272 - 113,927,877 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013118,580,480 - 118,618,039 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413111,078,338 - 111,113,667 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113111,281,069 - 111,300,233 (-)NCBI
Celera13106,107,601 - 106,138,227 (-)NCBICelera
Cytogenetic Map13q27NCBI
Cr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540642,876,966 - 42,911,564 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540642,877,041 - 42,910,970 (+)NCBIChiLan1.0ChiLan1.0
CR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2141,889,483 - 41,926,416 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1141,855,514 - 41,892,457 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01183,052,798 - 183,088,385 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11187,330,483 - 187,366,069 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1187,330,483 - 187,366,069 (+)Ensemblpanpan1.1panPan2
Cr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934468,006,478 - 68,043,276 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365575,246,770 - 5,256,608 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12521,914,690 - 21,954,244 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2521,919,393 - 21,953,659 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605522,536,015 - 22,575,130 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248074,152,230 - 4,179,211 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248074,149,472 - 4,179,269 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:962
Count of miRNA genes:519
Interacting mature miRNAs:633
Transcripts:ENSMUST00000082321
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1558802Skmw6_mskeletal muscle weight 6 (mouse)Not determined1167954584195154279Mouse
1559024Zit1_mzinc induced tolerance 1 (mouse)Not determined1167462514195154279Mouse
1301652Cpfd2_mcerebellum pattern fissures (mouse)Not determined1172303451195154279Mouse
1301339Hdlq15_mHDL QTL 15 (mouse)Not determined1165873675195154279Mouse
12880429V25Dq1_mvitamin D inactive form serum level QTL 1 (mouse)1172632197195154279Mouse
10043863Swrl5_mSWR lupus locus 5 (mouse)Not determined1172303451195154279Mouse
12880426V25Dq2_mvitamin D inactive form serum level QTL 2 (mouse)1172532197195154279Mouse
11049575Lmr8b_mleishmaniasis resistance 8b (mouse)1172303451195154279Mouse
1301251Scc3_mcolon tumor susceptibility 3 (mouse)Not determined1168213823195154279Mouse
1357732Tbbmd1_mtotal body bone mineral density 1 (mouse)Not determined1171983110195154279Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161201261195154279Mouse
4141483Femwf7_mfemur work to failure 7 (mouse)Not determined167462514195154279Mouse
1302023Orch4_mautoimmune orchitis resistance 4 (mouse)Not determined1175211318195154279Mouse
1302158Fembrs5_mfemur breaking strength 5 (mouse)Not determined1167462514195154279Mouse
1301132Mors1_mmodifier of obesity related sterility 1 (mouse)Not determined1170379500195154279Mouse

Markers in Region
Cr2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381195,149,988 - 195,150,044UniSTSGRCm38
MGSCv371196,976,182 - 196,976,238UniSTSGRCm37
Celera1202,049,150 - 202,049,206UniSTS
Cytogenetic Map1H6UniSTS
cM Map1106.6UniSTS
Cr2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H6UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001368765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006497222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006497224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006497225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017314050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_865893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC109145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC139206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF168683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH003209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK007487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC109344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC109345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M29281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M35684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M35685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M36470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M61132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M81083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M81084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X98171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000043104   ⟹   ENSMUSP00000044261
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1194,848,053 - 194,853,476 (-)Ensembl
GRCm38.p6 Ensembl1195,165,745 - 195,171,168 (-)Ensembl
Ensembl Acc Id: ENSMUST00000082321   ⟹   ENSMUSP00000080938
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1194,819,119 - 194,859,023 (-)Ensembl
GRCm38.p6 Ensembl1195,136,811 - 195,176,715 (-)Ensembl
Ensembl Acc Id: ENSMUST00000192604
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1194,821,627 - 194,836,545 (-)Ensembl
GRCm38.p6 Ensembl1195,139,319 - 195,154,237 (-)Ensembl
Ensembl Acc Id: ENSMUST00000193356   ⟹   ENSMUSP00000141706
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1194,819,125 - 194,842,060 (-)Ensembl
GRCm38.p6 Ensembl1195,136,817 - 195,159,752 (-)Ensembl
Ensembl Acc Id: ENSMUST00000193436   ⟹   ENSMUSP00000142147
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1194,821,977 - 194,833,898 (-)Ensembl
GRCm38.p6 Ensembl1195,139,669 - 195,151,590 (-)Ensembl
Ensembl Acc Id: ENSMUST00000193801   ⟹   ENSMUSP00000141276
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1194,821,997 - 194,858,956 (-)Ensembl
GRCm38.p6 Ensembl1195,139,689 - 195,176,648 (-)Ensembl
Ensembl Acc Id: ENSMUST00000194149
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1194,845,506 - 194,850,725 (-)Ensembl
GRCm38.p6 Ensembl1195,163,198 - 195,168,417 (-)Ensembl
Ensembl Acc Id: ENSMUST00000195120   ⟹   ENSMUSP00000141538
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1194,819,119 - 194,859,024 (-)Ensembl
GRCm38.p6 Ensembl1195,136,811 - 195,176,716 (-)Ensembl
Ensembl Acc Id: ENSMUST00000195347
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1194,848,140 - 194,859,023 (-)Ensembl
GRCm38.p6 Ensembl1195,165,832 - 195,176,715 (-)Ensembl
Ensembl Acc Id: ENSMUST00000195722
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1194,852,953 - 194,859,023 (-)Ensembl
GRCm38.p6 Ensembl1195,170,645 - 195,176,715 (-)Ensembl
Ensembl Acc Id: ENSMUST00000195737
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1194,823,072 - 194,836,636 (-)Ensembl
GRCm38.p6 Ensembl1195,140,764 - 195,154,328 (-)Ensembl
Ensembl Acc Id: ENSMUST00000210219   ⟹   ENSMUSP00000147804
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1194,823,498 - 194,858,918 (-)Ensembl
GRCm38.p6 Ensembl1195,141,190 - 195,176,610 (-)Ensembl
Ensembl Acc Id: ENSMUST00000238929
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1194,821,976 - 194,845,926 (-)Ensembl
GRCm38.p6 Ensembl1195,139,668 - 195,163,618 (-)Ensembl
RefSeq Acc Id: NM_001368765   ⟹   NP_001355694
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391194,819,120 - 194,859,027 (-)NCBI
GRCm381195,136,812 - 195,176,719 (-)NCBI
Sequence:
RefSeq Acc Id: NM_007758   ⟹   NP_031784
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391194,819,120 - 194,859,027 (-)NCBI
GRCm381195,136,812 - 195,176,719 (-)NCBI
MGSCv371196,963,005 - 197,002,909 (-)RGD
Celera1202,035,969 - 202,075,750 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006497222   ⟹   XP_006497285
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391194,819,555 - 194,858,918 (-)NCBI
GRCm381195,137,242 - 195,176,880 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006497224   ⟹   XP_006497287
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391194,819,555 - 194,858,956 (-)NCBI
GRCm381195,136,811 - 195,176,877 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006497225   ⟹   XP_006497288
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391194,819,555 - 194,859,096 (-)NCBI
GRCm381195,136,811 - 195,176,875 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017314050   ⟹   XP_017169539
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391194,819,555 - 194,850,725 (-)NCBI
GRCm381195,136,811 - 195,168,417 (-)NCBI
Sequence:
RefSeq Acc Id: XR_865893
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391194,819,125 - 194,858,918 (-)NCBI
GRCm381195,136,817 - 195,176,880 (-)NCBI
Sequence:
RefSeq Acc Id: NP_031784   ⟸   NM_007758
- Peptide Label: isoform 2 precursor
- UniProtKB: P19070 (UniProtKB/Swiss-Prot),   Q9DC83 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006497287   ⟸   XM_006497224
- Peptide Label: isoform X2
- UniProtKB: P19070 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006497288   ⟸   XM_006497225
- Peptide Label: isoform X3
- UniProtKB: P19070 (UniProtKB/Swiss-Prot),   Q9DC83 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006497285   ⟸   XM_006497222
- Peptide Label: isoform X1
- UniProtKB: A0A1B0GS59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017169539   ⟸   XM_017314050
- Peptide Label: isoform X4
- UniProtKB: P19070 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001355694   ⟸   NM_001368765
- Peptide Label: isoform 1 precursor
- UniProtKB: A0A1B0GS59 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000147804   ⟸   ENSMUST00000210219
Ensembl Acc Id: ENSMUSP00000141276   ⟸   ENSMUST00000193801
Ensembl Acc Id: ENSMUSP00000141706   ⟸   ENSMUST00000193356
Ensembl Acc Id: ENSMUSP00000142147   ⟸   ENSMUST00000193436
Ensembl Acc Id: ENSMUSP00000141538   ⟸   ENSMUST00000195120
Ensembl Acc Id: ENSMUSP00000080938   ⟸   ENSMUST00000082321
Ensembl Acc Id: ENSMUSP00000044261   ⟸   ENSMUST00000043104
Protein Domains
Sushi

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P19070-F1-model_v2 AlphaFold P19070 1-1025 view protein structure

Promoters
RGD ID:6876200
Promoter ID:EPDNEW_M1551
Type:single initiation site
Name:Cr2_1
Description:Mus musculus complement receptor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M1552  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381195,151,542 - 195,151,602EPDNEW
RGD ID:6876202
Promoter ID:EPDNEW_M1552
Type:multiple initiation site
Name:Cr2_2
Description:Mus musculus complement receptor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M1551  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381195,176,719 - 195,176,779EPDNEW
RGD ID:6817556
Promoter ID:MM_KWN:3387
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Spleen
Transcripts:ENSMUST00000027917,   ENSMUST00000043104,   NM_007758,   UC007EFA.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361197,002,686 - 197,003,186 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88489 AgrOrtholog
Ensembl Genes ENSMUSG00000026616 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000043104.9 UniProtKB/TrEMBL
  ENSMUST00000082321 ENTREZGENE
  ENSMUST00000082321.9 UniProtKB/TrEMBL
  ENSMUST00000193356.2 UniProtKB/TrEMBL
  ENSMUST00000193436.2 UniProtKB/TrEMBL
  ENSMUST00000193801.2 UniProtKB/TrEMBL
  ENSMUST00000195120.6 UniProtKB/TrEMBL
  ENSMUST00000210219 ENTREZGENE
  ENSMUST00000210219.2 UniProtKB/TrEMBL
Gene3D-CATH Complement Module, domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Compl-Cell_Adhes-Reg UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi/SCR/CCP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi_SCR_CCP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:88489 ENTREZGENE
NCBI Gene 12902 ENTREZGENE
PANTHER COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  COMPLEMENT RECEPTOR TYPE 1 UniProtKB/TrEMBL
  COMPLEMENT RECEPTOR TYPE 2 UniProtKB/TrEMBL
  SUSHI DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sushi UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cr2 PhenoGen
PROSITE SUSHI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CCP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57535 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A6YWG3_MOUSE UniProtKB/TrEMBL
  A0A0A6YWU7_MOUSE UniProtKB/TrEMBL
  A0A0A6YXU7_MOUSE UniProtKB/TrEMBL
  A0A1B0GS59 ENTREZGENE, UniProtKB/TrEMBL
  CR2_MOUSE UniProtKB/Swiss-Prot
  E9Q3S5_MOUSE UniProtKB/TrEMBL
  P19070 ENTREZGENE
  Q32M14_MOUSE UniProtKB/TrEMBL
  Q6LAP4_MOUSE UniProtKB/TrEMBL
  Q99254_MOUSE UniProtKB/TrEMBL
  Q9CVM1_MOUSE UniProtKB/TrEMBL
  Q9DC83 ENTREZGENE, UniProtKB/TrEMBL