Fli1 (Friend leukemia integration 1) - Rat Genome Database

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Gene: Fli1 (Friend leukemia integration 1) Mus musculus
Analyze
Symbol: Fli1
Name: Friend leukemia integration 1
RGD ID: 1320395
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including blood circulation; megakaryocyte development; and regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study systemic scleroderma. Human ortholog(s) of this gene implicated in blood platelet disease and thrombocytopenia. Orthologous to human FLI1 (Fli-1 proto-oncogene, ETS transcription factor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EWS; EWSR2; Fli; Fli-1; Friend leukemia integration 1 transcription factor; retroviral integration site protein Fli-1; Si; SIC; SIC-1; Sic1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39932,333,500 - 32,454,292 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl932,333,500 - 32,454,157 (-)EnsemblGRCm39 Ensembl
GRCm38932,422,204 - 32,543,432 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl932,422,204 - 32,542,861 (-)EnsemblGRCm38mm10GRCm38
MGSCv37932,229,793 - 32,348,953 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36932,171,773 - 32,290,933 (-)NCBIMGSCv36mm8
Celera929,685,381 - 29,804,572 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map917.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
anagrelide  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium dichloride  (ISO)
choline  (EXP)
chromium(6+)  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
dimethylarsinic acid  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
finasteride  (ISO)
flutamide  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
gentamycin  (ISO)
indometacin  (ISO)
L-methionine  (EXP)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (EXP)
N-nitrosodimethylamine  (ISO)
nickel sulfate  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
romidepsin  (ISO)
SB 431542  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
Soman  (ISO)
succimer  (EXP)
sulindac  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
tributylstannane  (ISO)
trichostatin A  (ISO)
valproic acid  (EXP,ISO)
vincaleukoblastine  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal arteriole morphology  (IAGP)
abnormal B cell differentiation  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal brain meninges morphology  (IAGP)
abnormal class switch recombination  (IAGP)
abnormal erythropoiesis  (IAGP)
abnormal humoral immune response  (IAGP)
abnormal leukocyte morphology  (IAGP)
abnormal megakaryocyte differentiation  (IAGP)
abnormal megakaryocyte morphology  (IAGP)
abnormal megakaryocyte progenitor cell morphology  (IAGP)
abnormal pericyte morphology  (IAGP)
abnormal proerythroblast morphology  (IAGP)
abnormal splenic cell ratio  (IAGP)
abnormal thrombopoiesis  (IAGP)
abnormal vascular development  (IAGP)
abnormal vascular smooth muscle morphology  (IAGP)
abnormal venule morphology  (IAGP)
anemia  (IAGP)
aneurysm  (IAGP)
decreased B cell number  (IAGP)
decreased B cell proliferation  (IAGP)
decreased body weight  (IAGP)
decreased embryo size  (IAGP)
decreased follicular B cell number  (IAGP)
decreased granulocyte number  (IAGP)
decreased hematocrit  (IAGP)
decreased IgG1 level  (IAGP)
decreased IgG3 level  (IAGP)
decreased megakaryocyte cell number  (IAGP)
decreased thymocyte number  (IAGP)
dilated capillary  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
enlarged spleen  (IAGP)
hemorrhage  (IAGP)
impaired hematopoiesis  (IAGP)
increased erythrocyte cell number  (IAGP)
increased erythroid progenitor cell number  (IAGP)
increased leukemia incidence  (IAGP)
increased marginal zone B cell number  (IAGP)
increased monocyte cell number  (IAGP)
increased NK cell number  (IAGP)
increased transitional stage B cell number  (IAGP)
increased vascular endothelial cell number  (IAGP)
increased vascular permeability  (IAGP)
intracranial hemorrhage  (IAGP)
intraventricular hemorrhage  (IAGP)
pale liver  (IAGP)
pale yolk sac  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
small liver  (IAGP)
spinal hemorrhage  (IAGP)
spleen hyperplasia  (IAGP)
thrombocytopenia  (IAGP)
vascular stenosis  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. MGD IEA MGD IEA
3. FLI1 monoallelic expression combined with its hemizygous loss underlies Paris-Trousseau/Jacobsen thrombopenia. Raslova H, etal., J Clin Invest. 2004 Jul;114(1):77-84.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1445800   PMID:1522903   PMID:1845910   PMID:1916807   PMID:2044959   PMID:2304901   PMID:7558020   PMID:8439553   PMID:8439730   PMID:8474456   PMID:8502483   PMID:8524263  
PMID:8570653   PMID:8649378   PMID:8679708   PMID:8838310   PMID:8987796   PMID:10095055   PMID:10199918   PMID:10349636   PMID:10523830   PMID:10640707   PMID:10704859   PMID:10757781  
PMID:10891501   PMID:10981960   PMID:11042159   PMID:11076861   PMID:11118632   PMID:11217851   PMID:11503960   PMID:12065417   PMID:12200699   PMID:12379474   PMID:12466851   PMID:12466854  
PMID:12477932   PMID:12509448   PMID:12527908   PMID:14570912   PMID:14635793   PMID:14647452   PMID:15367440   PMID:15528390   PMID:15557108   PMID:15592502   PMID:15618518   PMID:16141072  
PMID:16141073   PMID:16484587   PMID:16757682   PMID:17606295   PMID:17907201   PMID:17962413   PMID:18084326   PMID:18287559   PMID:18500345   PMID:18641300   PMID:18648544   PMID:18692443  
PMID:18805961   PMID:19001092   PMID:19023080   PMID:19289502   PMID:19470763   PMID:19666492   PMID:19829305   PMID:20015093   PMID:20059953   PMID:20103643   PMID:20228226   PMID:20368343  
PMID:20400501   PMID:20430747   PMID:20445019   PMID:20517297   PMID:20731671   PMID:20733157   PMID:20823267   PMID:20887958   PMID:21148317   PMID:21267068   PMID:21451544   PMID:21677750  
PMID:21867929   PMID:21873635   PMID:21911838   PMID:22056786   PMID:22325351   PMID:22639370   PMID:23056458   PMID:23108091   PMID:23320737   PMID:23667468   PMID:24040398   PMID:24146773  
PMID:24375017   PMID:24580413   PMID:24708674   PMID:24727028   PMID:24935715   PMID:24952961   PMID:25084151   PMID:25098295   PMID:25108845   PMID:25155007   PMID:25504335   PMID:25591392  
PMID:25739401   PMID:25748132   PMID:25802403   PMID:25870111   PMID:26055516   PMID:26093983   PMID:26097038   PMID:26538397   PMID:26764384   PMID:26900987   PMID:27239041   PMID:27457419  
PMID:27471260   PMID:27570068   PMID:27777101   PMID:28232470   PMID:28248553   PMID:29038846   PMID:29415756   PMID:29945296   PMID:29947047   PMID:30739075   PMID:31898537   PMID:32508810  
PMID:33051146   PMID:33238123   PMID:33636129   PMID:33964960   PMID:34544261   PMID:35038582   PMID:35288713   PMID:35649376   PMID:36045707   PMID:37094946   PMID:37790939  


Genomics

Comparative Map Data
Fli1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39932,333,500 - 32,454,292 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl932,333,500 - 32,454,157 (-)EnsemblGRCm39 Ensembl
GRCm38932,422,204 - 32,543,432 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl932,422,204 - 32,542,861 (-)EnsemblGRCm38mm10GRCm38
MGSCv37932,229,793 - 32,348,953 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36932,171,773 - 32,290,933 (-)NCBIMGSCv36mm8
Celera929,685,381 - 29,804,572 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map917.74NCBI
FLI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811128,685,351 - 128,813,267 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11128,686,535 - 128,813,267 (+)EnsemblGRCh38hg38GRCh38
GRCh3711128,556,430 - 128,683,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611128,069,199 - 128,187,521 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411128,069,198 - 128,187,520NCBI
Celera11125,728,561 - 125,849,286 (+)NCBICelera
Cytogenetic Map11q24.3NCBI
HuRef11124,504,750 - 124,631,960 (+)NCBIHuRef
CHM1_111128,442,436 - 128,569,169 (+)NCBICHM1_1
T2T-CHM13v2.011128,719,763 - 128,845,984 (+)NCBIT2T-CHM13v2.0
Fli1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2830,831,422 - 30,950,468 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl830,832,753 - 30,950,433 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx834,903,577 - 35,021,956 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0833,197,989 - 33,316,402 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0831,060,872 - 31,179,270 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0833,541,932 - 33,661,111 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl833,543,258 - 33,661,049 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0833,586,162 - 33,704,455 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4832,187,952 - 32,309,782 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1832,196,722 - 32,318,548 (-)NCBI
Celera832,284,160 - 32,401,673 (-)NCBICelera
Cytogenetic Map8q21NCBI
Fli1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541229,654,459 - 29,775,903 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541229,653,621 - 29,773,412 (+)NCBIChiLan1.0ChiLan1.0
FLI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan111130,484,068 - 130,602,419 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011123,506,859 - 123,626,024 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111127,409,301 - 127,527,521 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11127,409,301 - 127,530,312 (+)Ensemblpanpan1.1panPan2
FLI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.155,841,533 - 5,968,329 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl55,843,023 - 5,966,822 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha55,899,065 - 6,025,150 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.055,799,196 - 5,922,120 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl55,799,200 - 5,920,609 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.155,858,425 - 5,981,002 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.055,836,777 - 5,962,717 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.055,870,453 - 5,993,208 (-)NCBIUU_Cfam_GSD_1.0
Fli1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947110,872,609 - 111,001,492 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365723,448,862 - 3,577,836 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365723,448,870 - 3,576,406 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FLI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl955,612,901 - 55,749,778 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1955,612,905 - 55,749,784 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2961,707,515 - 61,810,415 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FLI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11119,817,987 - 119,945,378 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1119,827,222 - 119,946,662 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660436,144,187 - 6,261,677 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fli1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248123,004,628 - 3,139,101 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248123,004,631 - 3,138,901 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fli1
4384 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:735
Count of miRNA genes:436
Interacting mature miRNAs:571
Transcripts:ENSMUST00000016231, ENSMUST00000183767
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300849Sles4_msystemic lupus erythmatosus suppressor 4 (mouse)Not determined9910756237306370Mouse
13504833Bglu19_mblood glucose level 19 (mouse)9991076843910768Mouse
1300532Tbs2_mtuberculosis severity 2 (mouse)Not determined91236997046370114Mouse
10043917Obq37_mobesity QTL 37 (mouse)Not determined91339117547391175Mouse
1357637Si5lq2_mserum IGFBP-5 level QTL 2 (mouse)Not determined91541175149411890Mouse
4141591Cq4_mcholesterol QTL 4 (mouse)Not determined91541175149411890Mouse
1301421Lgth4_mbody length 4 (mouse)Not determined91541175149411890Mouse
4141447Cfmq2_mcystic fibrosis modifier QTL 2 (mouse)Not determined91541175149411890Mouse
12790993Adq1_maortic diameter QTL 1 (mouse)91574962749749627Mouse
11354951Pdcc3_mplasmacytoid dentritic cell compartment 3 (mouse)91574962749749627Mouse
12790997Adq2_maortic diameter QTL 2 (mouse)91574962749749627Mouse
12880415V125Dq7_mvitamin D active form serum level QTL 7 (mouse)91601129650011296Mouse
12880416V125Dq8_mvitamin D active form serum level QTL 8 (mouse)91601129650011296Mouse
13504834Hdlq109_mHDL QTL 109 (mouse)91670964150709641Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91697884050978943Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined91994340653943525Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92015336254153492Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92030619754306370Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92030619754306370Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92030619754306370Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92030619754306370Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92085274054852740Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92491129668907282Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92558748559587581Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92558748559587581Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92558748559587581Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92558748559587581Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92679642160796552Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92679642160796552Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92679642160796552Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92725119461251323Mouse
14700787Ncdq1_mnevus cell density QTL 1 (mouse)92811129636111296Mouse
1301000Obq5_mobesity QTL 5 (mouse)Not determined92850333341799326Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92929292963293072Mouse
1301782Chol11_mcholesterol 11 (mouse)Not determined92929292963293072Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93005316464053277Mouse
1558949Igan3_mIgA nephropathy 3 (mouse)Not determined93041469440565914Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93073991564740021Mouse
4142455Elnv_mepilepsy naive (mouse)Not determined93127155837306370Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93243456366434857Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93245242166452546Mouse

Markers in Region
X59421  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38932,423,653 - 32,423,727UniSTSGRCm38
MGSCv37932,231,238 - 32,231,312UniSTSGRCm37
Celera929,686,826 - 29,686,900UniSTS
Cytogenetic Map9A4UniSTS
cM Map916.0UniSTS
Whitehead/MRC_RH9322.81UniSTS
Whitehead_YAC9 UniSTS
07.MMHAP31FLC1.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38932,534,180 - 32,534,345UniSTSGRCm38
MGSCv37932,341,765 - 32,341,930UniSTSGRCm37
Celera929,797,574 - 29,797,739UniSTS
Cytogenetic Map9A4UniSTS
cM Map916.0UniSTS
Whitehead_YAC9 UniSTS
D9Mit90  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38932,500,455 - 32,500,594UniSTSGRCm38
MGSCv37932,308,040 - 32,308,179UniSTSGRCm37
Celera929,763,796 - 29,763,945UniSTS
Cytogenetic Map9A4UniSTS
cM Map99.0UniSTS
Whitehead Genetic97.7UniSTS
Whitehead/MRC_RH9338.13UniSTS
Whitehead_YAC9 UniSTS
PMC86032P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38932,423,914 - 32,424,223UniSTSGRCm38
MGSCv37932,231,499 - 32,231,808UniSTSGRCm37
Celera929,687,087 - 29,687,396UniSTS
Cytogenetic Map9A4UniSTS
cM Map916.0UniSTS
Fli1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38932,423,739 - 32,423,883UniSTSGRCm38
MGSCv37932,231,324 - 32,231,468UniSTSGRCm37
Celera929,686,912 - 29,687,056UniSTS
Cytogenetic Map9A4UniSTS
cM Map916.0UniSTS
X59421  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38932,423,657 - 32,423,755UniSTSGRCm38
MGSCv37932,231,242 - 32,231,340UniSTSGRCm37
Celera929,686,830 - 29,686,928UniSTS
Cytogenetic Map9A4UniSTS
Whitehead/MRC_RH9322.81UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000016231   ⟹   ENSMUSP00000016231
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl932,333,500 - 32,452,891 (-)Ensembl
GRCm38.p6 Ensembl932,422,204 - 32,541,595 (-)Ensembl
RefSeq Acc Id: ENSMUST00000183767   ⟹   ENSMUSP00000138984
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl932,339,355 - 32,454,157 (-)Ensembl
GRCm38.p6 Ensembl932,428,059 - 32,542,861 (-)Ensembl
RefSeq Acc Id: NM_001410251   ⟹   NP_001397180
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39932,333,503 - 32,452,693 (-)NCBI
RefSeq Acc Id: NM_001410252   ⟹   NP_001397181
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39932,333,503 - 32,454,292 (-)NCBI
RefSeq Acc Id: NM_008026   ⟹   NP_032052
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39932,333,503 - 32,452,693 (-)NCBI
GRCm38932,422,204 - 32,541,452 (-)NCBI
MGSCv37932,229,793 - 32,348,953 (-)RGD
Celera929,685,377 - 29,804,656 (-)NCBI
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006510009   ⟹   XP_006510072
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39932,333,500 - 32,453,945 (-)NCBI
GRCm38932,422,204 - 32,542,632 (-)NCBI
Sequence:
RefSeq Acc Id: NP_032052   ⟸   NM_008026
- Peptide Label: isoform 1
- UniProtKB: P26323 (UniProtKB/Swiss-Prot),   Q544B3 (UniProtKB/TrEMBL),   Q8BZ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006510072   ⟸   XM_006510009
- Peptide Label: isoform X2
- UniProtKB: Q8BZ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000138984   ⟸   ENSMUST00000183767
RefSeq Acc Id: ENSMUSP00000016231   ⟸   ENSMUST00000016231
RefSeq Acc Id: NP_001397181   ⟸   NM_001410252
- Peptide Label: isoform 3
- UniProtKB: Q8BZ56 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397180   ⟸   NM_001410251
- Peptide Label: isoform 2
- UniProtKB: Q8BZ56 (UniProtKB/TrEMBL)
Protein Domains
ETS   PNT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P26323-F1-model_v2 AlphaFold P26323 1-452 view protein structure

Promoters
RGD ID:6844533
Promoter ID:MM_KWN:56759
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Lung,   MEF_B6,   Spleen
Transcripts:ENSMUST00000016231
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36932,348,511 - 32,349,552 (-)MPROMDB
RGD ID:8669130
Promoter ID:EPDNEW_M12596
Type:initiation region
Name:Fli1_1
Description:Mus musculus Friend leukemia integration 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38932,541,397 - 32,541,457EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95554 AgrOrtholog
Ensembl Genes ENSMUSG00000016087 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000016231 ENTREZGENE
  ENSMUST00000016231.14 UniProtKB/Swiss-Prot
  ENSMUST00000183767.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.150.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ets_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ETS_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pointed_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_PNT-FLI-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14247 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95554 ENTREZGENE
NCBI Gene 14247 ENTREZGENE
PANTHER PTHR11849 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11849:SF161 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ets UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_PNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fli1 PhenoGen
PRINTS ETSDOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ETS_DOMAIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ETS_DOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ETS_DOMAIN_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ETS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_PNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47769 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt FLI1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q544B3 ENTREZGENE, UniProtKB/TrEMBL
  Q8BJH6_MOUSE UniProtKB/TrEMBL
  Q8BZ56 ENTREZGENE, UniProtKB/TrEMBL
  V9GX50_MOUSE UniProtKB/TrEMBL