Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ate1 | Mouse | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | ATE1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ATE1 mRNA | CTD | PMID:22079256 | Ate1 | Mouse | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of ATE1 mRNA | CTD | PMID:17555576 | Ate1 | Mouse | 17alpha-ethynylestradiol | increases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in increased expression of ATE1 mRNA | CTD | PMID:29097150 | Ate1 | Mouse | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of ATE1 mRNA | CTD | PMID:17942748 | Ate1 | Mouse | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATE1 mRNA | CTD | PMID:17942748 | Ate1 | Mouse | 17beta-estradiol | affects expression | ISO | ATE1 (Homo sapiens) | 6480464 | Estradiol affects the expression of ATE1 mRNA | CTD | PMID:22574217 | Ate1 | Mouse | 17beta-estradiol | multiple interactions | ISO | Ate1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of ATE1 mRNA | CTD | PMID:26496021 | Ate1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATE1 mRNA | CTD | PMID:17942748 | Ate1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ATE1 mRNA | CTD | PMID:33387578 | Ate1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ATE1 mRNA | CTD | PMID:34747641 | Ate1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ATE1 mRNA | CTD | PMID:21570461 | Ate1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ATE1 mRNA | CTD | PMID:19465110 | Ate1 | Mouse | 3H-1,2-dithiole-3-thione | decreases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | 1 and 2-dithiol-3-thione results in decreased expression of ATE1 mRNA | CTD | PMID:19162173 | Ate1 | Mouse | 4,4'-sulfonyldiphenol | multiple interactions | ISO | ATE1 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in increased methylation of ATE1 gene | CTD | PMID:31601247 | Ate1 | Mouse | 4-amino-2,6-dinitrotoluene | affects expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of ATE1 mRNA | CTD | PMID:21346803 | Ate1 | Mouse | acetamide | decreases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | acetamide results in decreased expression of ATE1 mRNA | CTD | PMID:31881176 | Ate1 | Mouse | acrolein | multiple interactions | ISO | ATE1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ATE1 mRNA more ... | CTD | PMID:32699268 and PMID:32845096 | Ate1 | Mouse | acrylamide | decreases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | Acrylamide results in decreased expression of ATE1 mRNA | CTD | PMID:28959563 | Ate1 | Mouse | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of ATE1 mRNA | CTD | PMID:19770486 | Ate1 | Mouse | all-trans-retinoic acid | decreases expression | ISO | ATE1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ATE1 mRNA | CTD | PMID:33167477 | Ate1 | Mouse | alpha-pinene | multiple interactions | ISO | ATE1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ATE1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ATE1 mRNA | CTD | PMID:32699268 | Ate1 | Mouse | amitrole | increases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of ATE1 mRNA | CTD | PMID:38685447 | Ate1 | Mouse | aristolochic acid A | decreases expression | ISO | ATE1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ATE1 mRNA | CTD | PMID:33212167 | Ate1 | Mouse | arsenite(3-) | multiple interactions | ISO | ATE1 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to ATE1 mRNA] | CTD | PMID:32406909 | Ate1 | Mouse | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of ATE1 mRNA | CTD | PMID:19770486 | Ate1 | Mouse | benzo[a]pyrene | affects methylation | ISO | ATE1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ATE1 promoter | CTD | PMID:27901495 | Ate1 | Mouse | benzo[a]pyrene | increases methylation | ISO | ATE1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ATE1 3' UTR | CTD | PMID:27901495 | Ate1 | Mouse | benzo[a]pyrene | increases expression | ISO | ATE1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of ATE1 mRNA | CTD | PMID:26238291 | Ate1 | Mouse | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ATE1 mRNA | CTD | PMID:22228805 | Ate1 | Mouse | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ATE1 mRNA | CTD | PMID:26063408 and PMID:33221593 | Ate1 | Mouse | bisphenol A | affects expression | ISO | ATE1 (Homo sapiens) | 6480464 | bisphenol A affects the expression of ATE1 protein | CTD | PMID:34186270 | Ate1 | Mouse | bisphenol A | increases expression | ISO | ATE1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of ATE1 mRNA | CTD | PMID:32028606 | Ate1 | Mouse | bisphenol A | increases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of ATE1 mRNA | CTD | PMID:29097150 | Ate1 | Mouse | bisphenol A | affects expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of ATE1 mRNA | CTD | PMID:25181051 | Ate1 | Mouse | bisphenol A | multiple interactions | ISO | Ate1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of ATE1 mRNA | CTD | PMID:26496021 | Ate1 | Mouse | Bisphenol B | increases expression | ISO | ATE1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of ATE1 protein | CTD | PMID:34186270 | Ate1 | Mouse | bortezomib | increases expression | ISO | ATE1 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of ATE1 mRNA | CTD | PMID:20977926 | Ate1 | Mouse | C60 fullerene | decreases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | fullerene C60 results in decreased expression of ATE1 mRNA | CTD | PMID:19167457 | Ate1 | Mouse | caffeine | decreases phosphorylation | ISO | ATE1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of ATE1 protein | CTD | PMID:35688186 | Ate1 | Mouse | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ATE1 gene | CTD | PMID:20938992 | Ate1 | Mouse | cocaine | increases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | Cocaine results in increased expression of ATE1 mRNA | CTD | PMID:17898221 | Ate1 | Mouse | cyclosporin A | increases expression | ISO | ATE1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of ATE1 mRNA | CTD | PMID:25562108 | Ate1 | Mouse | doxorubicin | decreases expression | ISO | ATE1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ATE1 mRNA | CTD | PMID:29803840 | Ate1 | Mouse | ethyl methanesulfonate | decreases expression | ISO | ATE1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of ATE1 mRNA | CTD | PMID:23649840 | Ate1 | Mouse | fenofibrate | increases expression | EXP | | 6480464 | Fenofibrate results in increased expression of ATE1 mRNA | CTD | PMID:21318169 | Ate1 | Mouse | fenofibrate | multiple interactions | EXP | | 6480464 | PPARA protein affects the reaction [Fenofibrate results in increased expression of ATE1 mRNA] | CTD | PMID:21318169 | Ate1 | Mouse | finasteride | increases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | Finasteride results in increased expression of ATE1 mRNA | CTD | PMID:24136188 | Ate1 | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ATE1 gene | CTD | PMID:20938992 | Ate1 | Mouse | formaldehyde | decreases expression | ISO | ATE1 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of ATE1 mRNA | CTD | PMID:23649840 | Ate1 | Mouse | fulvestrant | multiple interactions | ISO | ATE1 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in increased methylation of ATE1 gene | CTD | PMID:31601247 | Ate1 | Mouse | ivermectin | decreases expression | ISO | ATE1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ATE1 protein | CTD | PMID:32959892 | Ate1 | Mouse | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ATE1 gene | CTD | PMID:20938992 | Ate1 | Mouse | methapyrilene | decreases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | Methapyrilene results in decreased expression of ATE1 mRNA | CTD | PMID:30467583 | Ate1 | Mouse | methidathion | decreases expression | EXP | | 6480464 | methidathion results in decreased expression of ATE1 mRNA | CTD | PMID:34813904 | Ate1 | Mouse | methimazole | increases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of ATE1 mRNA | CTD | PMID:38685447 | Ate1 | Mouse | N(4)-hydroxycytidine | decreases expression | EXP | | 6480464 | N(4)-hydroxycytidine results in decreased expression of ATE1 mRNA | CTD | PMID:37748715 | Ate1 | Mouse | ozone | multiple interactions | ISO | ATE1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ATE1 mRNA more ... | CTD | PMID:32699268 and PMID:32845096 | Ate1 | Mouse | paracetamol | decreases expression | ISO | ATE1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ATE1 mRNA | CTD | PMID:21420995 | Ate1 | Mouse | paracetamol | multiple interactions | EXP | | 6480464 | PANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of ATE1 mRNA] | CTD | PMID:29246445 | Ate1 | Mouse | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ATE1 mRNA | CTD | PMID:29246445 | Ate1 | Mouse | PCB138 | decreases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:23829299 | Ate1 | Mouse | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of ATE1 mRNA | CTD | PMID:23892564 | Ate1 | Mouse | pirinixic acid | multiple interactions | EXP | | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ATE1 mRNA more ... | CTD | PMID:19710929 more ... | Ate1 | Mouse | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of ATE1 mRNA | CTD | PMID:17426115 more ... | Ate1 | Mouse | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of ATE1 mRNA | CTD | PMID:20059764 | Ate1 | Mouse | potassium chromate | multiple interactions | ISO | ATE1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ATE1 mRNA | CTD | PMID:22079256 | Ate1 | Mouse | potassium chromate | decreases expression | ISO | ATE1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of ATE1 mRNA | CTD | PMID:22079256 | Ate1 | Mouse | resveratrol | decreases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | resveratrol results in decreased expression of ATE1 mRNA | CTD | PMID:25905778 | Ate1 | Mouse | sodium arsenite | increases expression | ISO | ATE1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ATE1 mRNA | CTD | PMID:38568856 | Ate1 | Mouse | sulindac | decreases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | Sulindac results in decreased expression of ATE1 mRNA | CTD | PMID:24136188 | Ate1 | Mouse | sunitinib | increases expression | ISO | ATE1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of ATE1 mRNA | CTD | PMID:31533062 | Ate1 | Mouse | tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of ATE1 mRNA | CTD | PMID:17555576 | Ate1 | Mouse | thioacetamide | increases expression | ISO | Ate1 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of ATE1 mRNA | CTD | PMID:23411599 and PMID:34492290 | Ate1 | Mouse | triphenyl phosphate | affects expression | ISO | ATE1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ATE1 mRNA | CTD | PMID:37042841 | Ate1 | Mouse | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of ATE1 mRNA | CTD | PMID:33045310 | Ate1 | Mouse | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of ATE1 mRNA | CTD | PMID:17292431 | |