Gli2 (GLI-Kruppel family member GLI2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Gli2 (GLI-Kruppel family member GLI2) Mus musculus
Analyze
Symbol: Gli2
Name: GLI-Kruppel family member GLI2
RGD ID: 1319523
MGI Page MGI
Description: Enables DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and promoter-specific chromatin binding activity. Involved in gene expression and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including embryonic morphogenesis; nervous system development; and tube morphogenesis. Located in several cellular components, including axoneme; ciliary tip; and nuclear speck. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; genitourinary system; and jaw. Human ortholog(s) of this gene implicated in Culler-Jones syndrome; holoprosencephaly 9; and spina bifida. Orthologous to human GLI2 (GLI family zinc finger 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AW546128; Tax helper protein; zinc finger protein GLI2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391118,761,791 - 118,987,578 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1118,761,862 - 118,981,349 (-)EnsemblGRCm39 Ensembl
GRCm381118,834,061 - 119,054,405 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1118,834,132 - 119,053,619 (-)EnsemblGRCm38mm10GRCm38
MGSCv371120,730,638 - 120,950,196 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361120,661,607 - 120,881,165 (-)NCBIMGSCv36mm8
Celera1121,494,112 - 121,713,823 (-)NCBICelera
Cytogenetic Map1E2.3NCBI
cM Map152.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dichloroethane  (EXP)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-D  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
4-hydroperoxycyclophosphamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
Ac-Ser-Asp-Lys-Pro-OH  (ISO)
acetaldehyde  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenous acid  (ISO)
aspartame  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
captopril  (ISO)
carbamazepine  (EXP)
CGP 52608  (ISO)
chromium(6+)  (EXP)
cisplatin  (ISO)
cocaine  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crotonaldehyde  (ISO)
curcumin  (ISO)
Cyclopamine  (ISO)
cyproconazole  (EXP)
D-glucose  (EXP,ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diethyl malate  (EXP)
disodium selenite  (EXP)
dorsomorphin  (ISO)
elemental selenium  (ISO)
embelin  (EXP,ISO)
endosulfan  (ISO)
ethanol  (EXP)
flusilazole  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
fructose  (EXP)
furan  (ISO)
gallic acid  (ISO)
gemcitabine  (ISO)
gentamycin  (ISO)
glucose  (EXP,ISO)
goralatide  (ISO)
lipopolysaccharide  (EXP)
LY294002  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methoxychlor  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
nitrofen  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
PCB138  (EXP)
potassium chromate  (ISO)
potassium dichromate  (EXP)
progesterone  (EXP)
quercetin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
sodium arsenite  (EXP)
Soman  (ISO)
sonidegib  (EXP,ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
triptonide  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vismodegib  (EXP,ISO)
vitamin E  (ISO)
zinc oxide  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anatomical structure formation involved in morphogenesis  (IGI)
anterior/posterior pattern specification  (IGI)
axon guidance  (IMP)
branching morphogenesis of an epithelial tube  (IMP)
cell differentiation  (IMP)
cell population proliferation  (IGI,IMP)
cellular response to organic cyclic compound  (IDA)
cellular response to virus  (ISO)
cerebellar cortex morphogenesis  (IGI,IMP)
chondrocyte differentiation  (IGI)
cochlea morphogenesis  (IMP)
developmental growth  (IMP)
dorsal/ventral neural tube patterning  (IDA,IMP)
dorsal/ventral pattern formation  (IGI)
embryonic digestive tract development  (IMP)
embryonic digit morphogenesis  (IMP)
epidermal cell differentiation  (ISO)
epithelial cell proliferation  (IGI,IMP)
floor plate formation  (IMP)
gene expression  (IMP)
hair follicle morphogenesis  (ISO)
head development  (IMP)
heart development  (IGI)
hindbrain development  (IGI,IMP)
hindgut morphogenesis  (IGI,IMP)
in utero embryonic development  (IMP)
kidney development  (IGI)
lung development  (IGI,IMP)
mammary gland development  (IMP)
mammary gland duct morphogenesis  (IMP)
morphogenesis of an epithelium  (IMP)
negative regulation of apoptotic process  (IDA)
negative regulation of chondrocyte differentiation  (IMP)
negative regulation of smoothened signaling pathway  (IGI)
negative regulation of transcription by RNA polymerase II  (IGI,ISO)
neural tube development  (IMP)
neuron development  (IMP)
neuron differentiation  (IGI)
notochord regression  (IGI)
odontogenesis of dentin-containing tooth  (IGI,IMP)
osteoblast development  (IDA,IMP)
osteoblast differentiation  (IGI,ISO)
pattern specification process  (IGI,IMP)
pituitary gland development  (IGI)
positive regulation of cell population proliferation  (IGI,IMP)
positive regulation of collagen biosynthetic process  (ISO)
positive regulation of DNA replication  (ISO)
positive regulation of DNA-templated transcription  (IDA,IMP,ISO)
positive regulation of epithelial cell proliferation  (IGI,IMP)
positive regulation of neuron differentiation  (IGI)
positive regulation of stem cell proliferation  (IMP)
positive regulation of transcription by RNA polymerase II  (IDA,IGI,ISO)
prostate gland development  (ISO)
prostatic bud formation  (IMP)
proximal/distal pattern formation  (IGI)
regulation of DNA-templated transcription  (ISS)
regulation of smoothened signaling pathway  (IGI)
regulation of transcription by RNA polymerase II  (IBA)
response to mechanical stimulus  (ISO)
skeletal system development  (IMP)
smoothened signaling pathway  (IBA,IGI,IMP,ISO)
smoothened signaling pathway involved in dorsal/ventral neural tube patterning  (IGI)
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification  (IGI)
smoothened signaling pathway involved in ventral spinal cord interneuron specification  (IGI)
spinal cord dorsal/ventral patterning  (IGI,IMP)
spinal cord motor neuron differentiation  (IMP)
spinal cord ventral commissure morphogenesis  (IMP)
stem cell proliferation  (IMP)
tube development  (IGI)
ventral midline development  (IGI,IMP)
ventral spinal cord development  (IMP)

Cellular Component
axoneme  (IDA)
cell projection  (IEA)
ciliary tip  (IDA)
cilium  (IDA)
cytoplasm  (IDA,IGI)
cytosol  (TAS)
membrane  (IDA)
motile cilium  (IDA)
nuclear speck  (IDA)
nucleolus  (IEA,ISO)
nucleoplasm  (ISO,TAS)
nucleus  (IBA,IDA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal basioccipital bone morphology  (IAGP)
abnormal basisphenoid bone morphology  (IAGP)
abnormal brain development  (IAGP)
abnormal bronchioalveolar stem cell morphology  (IAGP)
abnormal cartilage development  (IAGP)
abnormal cerebellar foliation  (IAGP)
abnormal cerebellar granule layer morphology  (IAGP)
abnormal cerebellar lobule formation  (IAGP)
abnormal cerebellar molecular layer  (IAGP)
abnormal cerebellar Purkinje cell layer  (IAGP)
abnormal cerebellum anterior vermis morphology  (IAGP)
abnormal cerebellum development  (IAGP)
abnormal cerebellum external granule cell layer morphology  (IAGP)
abnormal cerebellum morphology  (IAGP)
abnormal cerebellum vermis morphology  (IAGP)
abnormal developmental patterning  (IAGP)
abnormal diencephalon morphology  (IAGP)
abnormal digestive system morphology  (IAGP)
abnormal digit morphology  (IAGP)
abnormal dorsal-ventral axis patterning  (IAGP)
abnormal embryonic neuroepithelial layer differentiation  (IAGP)
abnormal endoderm development  (IAGP)
abnormal epiphyseal plate morphology  (IAGP)
abnormal esophageal smooth muscle morphology  (IAGP)
abnormal esophagus development  (IAGP)
abnormal external male genitalia morphology  (IAGP)
abnormal floor plate morphology  (IAGP)
abnormal foregut morphology  (IAGP)
abnormal frontal bone morphology  (IAGP)
abnormal gait  (IAGP)
abnormal head shape  (IAGP)
abnormal left lung morphology  (IAGP)
abnormal long bone morphology  (IAGP)
abnormal lung bud morphology  (IAGP)
abnormal lung development  (IAGP)
abnormal lung morphology  (IAGP)
abnormal mammary gland bud morphology  (IAGP)
abnormal maxillary dental arch morphology  (IAGP)
abnormal maxillary frontal process morphology  (IAGP)
abnormal motor neuron morphology  (IAGP)
abnormal neural tube closure  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal neuron differentiation  (IAGP)
abnormal neuron specification  (IAGP)
abnormal neuronal precursor cell number  (IAGP)
abnormal neuronal precursor proliferation  (IAGP)
abnormal notochord morphology  (IAGP)
abnormal palatal shelf elevation  (IAGP)
abnormal palatal shelf fusion at midline  (IAGP)
abnormal parietal bone morphology  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal right lung accessory lobe morphology  (IAGP)
abnormal right lung cranial lobe morphology  (IAGP)
abnormal right lung morphology  (IAGP)
abnormal rostral-caudal axis patterning  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal spinal cord interneuron morphology  (IAGP)
abnormal spinal cord morphology  (IAGP)
abnormal spine curvature  (IAGP)
abnormal telencephalon development  (IAGP)
abnormal telencephalon morphology  (IAGP)
abnormal trachea development  (IAGP)
abnormal tracheal cartilage morphology  (IAGP)
abnormal ventral interneuron 0 morphology  (IAGP)
abnormal ventral interneuron 1 morphology  (IAGP)
abnormal ventral interneuron 2 morphology  (IAGP)
abnormal ventral interneuron 3 morphology  (IAGP)
abnormal ventral interneuron morphology  (IAGP)
abnormal vertebrae development  (IAGP)
abnormal vertebral body morphology  (IAGP)
absent esophagus  (IAGP)
absent floor plate  (IAGP)
absent intervertebral disk  (IAGP)
absent lower incisors  (IAGP)
absent lungs  (IAGP)
absent maxillary shelf  (IAGP)
absent palatine bone horizontal plate  (IAGP)
absent pituitary gland  (IAGP)
absent presphenoid bone  (IAGP)
absent right lung accessory lobe  (IAGP)
absent temporomandibular joint disk  (IAGP)
absent trachea  (IAGP)
absent tympanic ring  (IAGP)
absent upper incisors  (IAGP)
bowed radius  (IAGP)
bradykinesia  (IAGP)
cleft secondary palate  (IAGP)
cryptorchism  (IAGP)
cyclopia  (IAGP)
decreased body size  (IAGP)
decreased chondrocyte number  (IAGP)
decreased embryo size  (IAGP)
decreased lung weight  (IAGP)
decreased mesenchymal cell proliferation involved in lung development  (IAGP)
decreased motor neuron number  (IAGP)
decreased type II pneumocyte number  (IAGP)
delayed bone ossification  (IAGP)
edema  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic lethality prior to organogenesis  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
emphysema  (IAGP)
esophageal atresia  (IAGP)
esophagus hypoplasia  (IAGP)
esophagus stenosis  (IAGP)
exencephaly  (IAGP)
fusion of vertebral arches  (IAGP)
hydrocephaly  (IAGP)
impaired balance  (IAGP)
impaired limb coordination  (IAGP)
impaired lung lobe morphogenesis  (IAGP)
impaired righting response  (IAGP)
incomplete rostral neuropore closure  (IAGP)
increased motor neuron number  (IAGP)
increased neuronal precursor cell number  (IAGP)
increased rib number  (IAGP)
increased type II pneumocyte number  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
male infertility  (IAGP)
mandible hypoplasia  (IAGP)
megacephaly  (IAGP)
microcephaly  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
overexpanded pulmonary alveolus  (IAGP)
perinatal lethality  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
persistence of notochord tissue  (IAGP)
polydactyly  (IAGP)
polyphalangy  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IAGP)
progressive hair loss  (IAGP)
pulmonary hypoplasia  (IAGP)
reduced cerebellar foliation  (IAGP)
short femur  (IAGP)
short fibula  (IAGP)
short humerus  (IAGP)
short limbs  (IAGP)
short maxilla  (IAGP)
short radius  (IAGP)
short sternum  (IAGP)
short tibia  (IAGP)
short ulna  (IAGP)
small cerebellum  (IAGP)
small lung  (IAGP)
small lung saccule  (IAGP)
small mandible  (IAGP)
small mandibular condyloid process  (IAGP)
split sternum  (IAGP)
thick lung-associated mesenchyme  (IAGP)
thin external granule cell layer  (IAGP)
trachea hypoplasia  (IAGP)
trachea stenosis  (IAGP)
tracheoesophageal fistula  (IAGP)
tremors  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Hedgehog signaling update. Cohen MM, Am J Med Genet A. 2010 Aug;152A(8):1875-914. doi: 10.1002/ajmg.a.32909.
2. Sonic hedgehog (SHH) and glioblastoma-2 (Gli-2) expressions are associated with poor jaundice-free survival in biliary atresia. Jung HY, etal., J Pediatr Surg. 2015 Mar;50(3):371-6. doi: 10.1016/j.jpedsurg.2014.08.025. Epub 2014 Dec 20.
3. Murine models of VACTERL syndrome: Role of sonic hedgehog signaling pathway. Kim PC, etal., J Pediatr Surg. 2001 Feb;36(2):381-4. doi: 10.1053/jpsu.2001.20722.
4. Genetic research and structural dysplasia assessment of anorectal malformations in neonatal male rats induced by di(n-butyl) phthalate. Liu ZH, etal., Environ Toxicol. 2016 Mar;31(3):261-8. doi: 10.1002/tox.22040. Epub 2014 Sep 12.
5. Sonic Hedgehog Signaling Affected by Promoter Hypermethylation Induces Aberrant Gli2 Expression in Spina Bifida. Lu XL, etal., Mol Neurobiol. 2016 Oct;53(8):5413-24. doi: 10.1007/s12035-015-9447-0. Epub 2015 Oct 7.
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies. Mimeault M and Batra SK, Pharmacol Rev. 2010 Sep;62(3):497-524.
9. Anorectal malformations caused by defects in sonic hedgehog signaling. Mo R, etal., Am J Pathol. 2001 Aug;159(2):765-74.
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
13. Mouse MP Annotation Import Pipeline RGD automated import pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Defective sonic hedgehog signaling in esophageal atresia with tracheoesophageal fistula. Spilde TL, etal., Surgery. 2003 Aug;134(2):345-50.
17. Down-regulation of SHH/BMP4 signalling in human anorectal malformations. Zhang J, etal., J Int Med Res. 2009 Nov-Dec;37(6):1842-50.
Additional References at PubMed
PMID:8150204   PMID:8387379   PMID:8575294   PMID:9006072   PMID:9027508   PMID:9118802   PMID:9152005   PMID:9178901   PMID:9216996   PMID:9247260   PMID:9268579   PMID:9438426  
PMID:9636069   PMID:9655799   PMID:9655803   PMID:9671585   PMID:9731531   PMID:9768360   PMID:9768363   PMID:9988217   PMID:10027293   PMID:10098408   PMID:10330024   PMID:10349636  
PMID:10375501   PMID:10409510   PMID:10512189   PMID:10512203   PMID:10529434   PMID:10531011   PMID:10534616   PMID:10564661   PMID:10572046   PMID:10631181   PMID:10693670   PMID:10700170  
PMID:10725236   PMID:10806483   PMID:10888606   PMID:10922068   PMID:10981962   PMID:11023872   PMID:11042159   PMID:11044393   PMID:11044609   PMID:11076861   PMID:11118884   PMID:11217851  
PMID:11238441   PMID:11389830   PMID:11472847   PMID:11472848   PMID:11684660   PMID:11748151   PMID:11748155   PMID:11781239   PMID:11783999   PMID:11943666   PMID:12051813   PMID:12076333  
PMID:12142027   PMID:12221011   PMID:12361967   PMID:12385751   PMID:12403705   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12533516   PMID:12679031   PMID:12752768   PMID:12812795  
PMID:12837627   PMID:12904583   PMID:14568100   PMID:14602680   PMID:14610273   PMID:14633591   PMID:14681189   PMID:14723851   PMID:14973295   PMID:14980515   PMID:15039437   PMID:15215207  
PMID:15315762   PMID:15315763   PMID:15496441   PMID:15604102   PMID:15614767   PMID:15618518   PMID:15647317   PMID:15668330   PMID:15741177   PMID:15793308   PMID:15806168   PMID:15811134  
PMID:15840001   PMID:15841179   PMID:16054035   PMID:16141072   PMID:16141073   PMID:16168717   PMID:16247775   PMID:16254602   PMID:16267219   PMID:16284117   PMID:16316410   PMID:16342201  
PMID:16364285   PMID:16396903   PMID:16459298   PMID:16510500   PMID:16543460   PMID:16553965   PMID:16571352   PMID:16571625   PMID:16571630   PMID:16602821   PMID:16611981   PMID:16651270  
PMID:16678815   PMID:16707121   PMID:16880529   PMID:16914490   PMID:16916379   PMID:16950124   PMID:16958114   PMID:17026983   PMID:17035233   PMID:17187775   PMID:17191253   PMID:17199044  
PMID:17202190   PMID:17257418   PMID:17283082   PMID:17328886   PMID:17395647   PMID:17442891   PMID:17638910   PMID:17721996   PMID:17967808   PMID:18083924   PMID:18262513   PMID:18272593  
PMID:18279667   PMID:18287559   PMID:18298960   PMID:18417110   PMID:18590716   PMID:18632939   PMID:18676816   PMID:18688029   PMID:18710724   PMID:18728187   PMID:18799693   PMID:18832395  
PMID:18927156   PMID:18927476   PMID:19049965   PMID:19056373   PMID:19103752   PMID:19116665   PMID:19124651   PMID:19168680   PMID:19223390   PMID:19273836   PMID:19286674   PMID:19287388  
PMID:19325126   PMID:19325248   PMID:19445942   PMID:19474320   PMID:19487286   PMID:19505455   PMID:19536807   PMID:19549984   PMID:19574535   PMID:19581591   PMID:19632216   PMID:19647223  
PMID:19654211   PMID:19666503   PMID:19684112   PMID:19686689   PMID:19783738   PMID:19815519   PMID:19842175   PMID:19906844   PMID:19906864   PMID:19955409   PMID:19996169   PMID:20008041  
PMID:20059953   PMID:20081843   PMID:20154143   PMID:20159594   PMID:20430747   PMID:20463034   PMID:20479231   PMID:20503377   PMID:20516201   PMID:20637749   PMID:20668186   PMID:20711444  
PMID:20934421   PMID:20943901   PMID:20956384   PMID:20962855   PMID:21045211   PMID:21093585   PMID:21151991   PMID:21194568   PMID:21209331   PMID:21209421   PMID:21209912   PMID:21211521  
PMID:21267068   PMID:21289193   PMID:21303853   PMID:21307096   PMID:21337666   PMID:21339645   PMID:21364421   PMID:21451052   PMID:21454528   PMID:21549329   PMID:21552265   PMID:21559470  
PMID:21586556   PMID:21653639   PMID:21664576   PMID:21703454   PMID:21731673   PMID:21775418   PMID:21803035   PMID:21873635   PMID:21884692   PMID:21935430   PMID:21937600   PMID:22007132  
PMID:22083510   PMID:22178118   PMID:22182519   PMID:22228100   PMID:22232070   PMID:22265416   PMID:22275805   PMID:22281533   PMID:22342522   PMID:22371696   PMID:22402963   PMID:22465667  
PMID:22493482   PMID:22547067   PMID:22549777   PMID:22595669   PMID:22659622   PMID:22689656   PMID:22698544   PMID:22711520   PMID:22771375   PMID:22841643   PMID:22869526   PMID:22889265  
PMID:22935613   PMID:22987640   PMID:22988430   PMID:23034632   PMID:23110168   PMID:23166838   PMID:23177959   PMID:23201579   PMID:23201751   PMID:23249739   PMID:23266329   PMID:23308271  
PMID:23332756   PMID:23333501   PMID:23371063   PMID:23383082   PMID:23423383   PMID:23482494   PMID:23530031   PMID:23604909   PMID:23618354   PMID:23645682   PMID:23650387   PMID:23754280  
PMID:23762415   PMID:23872071   PMID:23872235   PMID:23877428   PMID:23916850   PMID:23988578   PMID:24016759   PMID:24036067   PMID:24073291   PMID:24076664   PMID:24121003   PMID:24146773  
PMID:24174682   PMID:24194188   PMID:24198274   PMID:24217340   PMID:24218555   PMID:24260306   PMID:24302887   PMID:24373970   PMID:24463817   PMID:24498290   PMID:24586787   PMID:24617895  
PMID:24693967   PMID:24726283   PMID:24780629   PMID:24813615   PMID:24886827   PMID:24948802   PMID:24952464   PMID:25083987   PMID:25150496   PMID:25224227   PMID:25268479   PMID:25366972  
PMID:25448692   PMID:25458012   PMID:25581370   PMID:25609427   PMID:25631042   PMID:25644602   PMID:25652406   PMID:25695606   PMID:25753732   PMID:25760946   PMID:25804738   PMID:25808752  
PMID:25833741   PMID:25834022   PMID:25848030   PMID:25859222   PMID:25908851   PMID:25910616   PMID:26001200   PMID:26010061   PMID:26015562   PMID:26057579   PMID:26094741   PMID:26193634  
PMID:26238488   PMID:26257608   PMID:26387942   PMID:26439398   PMID:26439735   PMID:26697723   PMID:26745185   PMID:26795056   PMID:26884322   PMID:26959361   PMID:27320915   PMID:27414999  
PMID:27494603   PMID:27543868   PMID:27585885   PMID:27657450   PMID:27760825   PMID:27802276   PMID:27814383   PMID:27849569   PMID:27893742   PMID:27930311   PMID:28027321   PMID:28069795  
PMID:28127049   PMID:28264835   PMID:28280246   PMID:28286175   PMID:28344083   PMID:28379358   PMID:28380258   PMID:28412462   PMID:28432216   PMID:28434801   PMID:28461568   PMID:28533268  
PMID:28560839   PMID:28673820   PMID:28688895   PMID:28778798   PMID:28793255   PMID:28794157   PMID:28799057   PMID:28800946   PMID:28817564   PMID:28916710   PMID:28939119   PMID:29038301  
PMID:29166577   PMID:29202464   PMID:29205155   PMID:29311969   PMID:29342244   PMID:29386106   PMID:29487109   PMID:29487191   PMID:29532549   PMID:29659575   PMID:29729398   PMID:29879378  
PMID:29967343   PMID:29999500   PMID:30001532   PMID:30111653   PMID:30153454   PMID:30250269   PMID:30301781   PMID:30352686   PMID:30389913   PMID:30463852   PMID:30554998   PMID:30764875  
PMID:30791390   PMID:30814516   PMID:30843071   PMID:30914320   PMID:31000813   PMID:31036156   PMID:31167144   PMID:31226309   PMID:31264977   PMID:31436046   PMID:31604927   PMID:31883643  
PMID:31964774   PMID:32001436   PMID:32169553   PMID:32234482   PMID:32253237   PMID:32325033   PMID:32332736   PMID:32497091   PMID:32662771   PMID:32674056   PMID:32702291   PMID:32747435  
PMID:32758357   PMID:32855417   PMID:32938678   PMID:33006313   PMID:33103996   PMID:33125874   PMID:33530552   PMID:33728992   PMID:33895473   PMID:34062094   PMID:34169076   PMID:34210780  
PMID:34242585   PMID:34267186   PMID:34321999   PMID:34346313   PMID:34433966   PMID:34767969   PMID:34772739   PMID:35048440   PMID:35112129   PMID:35145123   PMID:35377797   PMID:35418691  
PMID:35652338   PMID:35682694   PMID:36218069   PMID:36252002   PMID:36272934   PMID:36395107   PMID:36459481   PMID:36916392   PMID:37228654   PMID:37478645   PMID:37497597   PMID:37516749  
PMID:37541211   PMID:37943875   PMID:38117649   PMID:38358805   PMID:38385859   PMID:38466355   PMID:38602877   PMID:38750698   PMID:38848388   PMID:39001875   PMID:39029571   PMID:39125754  


Genomics

Comparative Map Data
Gli2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391118,761,791 - 118,987,578 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1118,761,862 - 118,981,349 (-)EnsemblGRCm39 Ensembl
GRCm381118,834,061 - 119,054,405 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1118,834,132 - 119,053,619 (-)EnsemblGRCm38mm10GRCm38
MGSCv371120,730,638 - 120,950,196 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361120,661,607 - 120,881,165 (-)NCBIMGSCv36mm8
Celera1121,494,112 - 121,713,823 (-)NCBICelera
Cytogenetic Map1E2.3NCBI
cM Map152.17NCBI
GLI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382120,735,868 - 120,992,653 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2120,735,623 - 120,992,653 (+)EnsemblGRCh38hg38GRCh38
GRCh372121,493,444 - 121,750,229 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362121,266,327 - 121,466,321 (+)NCBINCBI36Build 36hg18NCBI36
Celera2114,879,848 - 115,075,199 (+)NCBICelera
Cytogenetic Map2q14.2NCBI
HuRef2113,876,969 - 114,072,693 (+)NCBIHuRef
CHM1_12121,559,011 - 121,754,271 (+)NCBICHM1_1
T2T-CHM13v2.02121,171,586 - 121,428,571 (+)NCBIT2T-CHM13v2.0
Gli2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81332,499,678 - 32,716,418 (-)NCBIGRCr8
mRatBN7.21329,946,882 - 30,163,589 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1329,946,809 - 30,163,574 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1332,529,564 - 32,585,620 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01333,817,400 - 33,873,458 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01331,093,715 - 31,149,850 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01334,829,021 - 35,049,172 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1334,829,139 - 35,048,444 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01339,955,094 - 40,170,750 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41331,551,089 - 31,607,264 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11331,555,563 - 31,574,381 (-)NCBI
Celera1329,844,054 - 29,900,050 (-)NCBICelera
Cytogenetic Map13q11NCBI
Gli2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554598,892,869 - 9,118,499 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554598,892,917 - 9,124,672 (-)NCBIChiLan1.0ChiLan1.0
GLI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21322,735,243 - 22,992,365 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B22,750,199 - 23,007,333 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B7,665,403 - 7,922,840 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B121,242,932 - 121,499,411 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B121,303,831 - 121,497,442 (+)Ensemblpanpan1.1panPan2
GLI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11929,128,401 - 29,383,324 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1929,130,227 - 29,383,658 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1929,385,203 - 29,640,495 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01930,500,404 - 30,754,986 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1930,501,230 - 30,755,556 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11929,191,227 - 29,444,875 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01929,361,839 - 29,547,733 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01930,542,746 - 30,798,466 (-)NCBIUU_Cfam_GSD_1.0
Gli2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530391,769,648 - 92,002,404 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646949,617,095 - 49,673,213 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646949,616,552 - 49,788,760 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLI2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1530,313,817 - 30,579,306 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11530,312,528 - 30,580,272 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21535,267,097 - 35,303,278 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GLI2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1109,302,890 - 9,561,287 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl109,304,645 - 9,369,115 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606113,127,973 - 13,388,785 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gli2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473224,159,312 - 24,328,452 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473224,159,407 - 24,381,495 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gli2
7417 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2524
Count of miRNA genes:648
Interacting mature miRNAs:814
Transcripts:ENSMUST00000062483, ENSMUST00000159678, ENSMUST00000159839, ENSMUST00000160991, ENSMUST00000161056, ENSMUST00000161301, ENSMUST00000161451, ENSMUST00000162552, ENSMUST00000162607
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
15039333Nmrs1_mNAFLD-associated magnetic resonance shift 1 (mouse)189786512123786512Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
12879492Ecgnq1_meccrine gland number QTL 1 (mouse)1103278062120535225Mouse
10045976Tir6_mtrypanosome infection response 6 (mouse)Not determined193536855120529678Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118099720152099816Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174991977133290937Mouse
4141627Bwq7_mbody weight, QTL 7 (mouse)Not determined192940909124497796Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195527725162027569Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
12879491Hfnq1_mhair follicle number QTL 1 (mouse)193310310123636759Mouse
1301979Melm1_mmelanoma modifier 1 (mouse)Not determined1109638262143638479Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
12790991Aath1_maortic arch atherosclerosis 1 (mouse)186483929120483929Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139132808126445310Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112008822168186402Mouse
1301123Cd8mts2_mCD8 memory T cell subset 2 (mouse)Not determined196618386130618557Mouse
12790994Aaaq1_maortic arch angle QTL 1 (mouse)1109495943143495943Mouse
10045640Jckm4_mjuvenile cystic kidney modifier 4 (mouse)Not determined1116290836150290937Mouse
1301249Sbw1_msplenomegaly-NZB x NZW 1 (mouse)Not determined1112131005146131085Mouse
1357760Synch3_msynechia 3 (mouse)Not determined192901442126901550Mouse
1301193Lxw3_mlupus BXSB x NZW 3 (mouse)Not determined1102968534136968667Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
13452398Leusq5_mleucocytosis susceptibility QTL 5 (mouse)198474785126386517Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
27095931Pglq1_mpelvic girdle length QTL 1, 5 week (mouse)175976637128527737Mouse
13452395Leusq2_mleucocytosis susceptibility QTL 2 (mouse)180245593126386517Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162946755120529678Mouse
1301753Tir3a_mtrypansomiasis infection response 3a (mouse)Not determined197053986131054190Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182643189135615379Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
4141329Mleu1_mmyeloid leukemia survival 1 (mouse)Not determined89786512123786512Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167339159129727737Mouse
1301536Pbbcp1_mperipheral blood B cell percentage 1 (mouse)Not determined199507660133507845Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194127725148775742Mouse
1357600Obq17_mobesity QTL 17 (mouse)Not determined1110553179144553298Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
10401248Bglu12_mblood glucose level 12 (mouse)Not determined1110553179144553298Mouse

Markers in Region
Gli2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381118,834,739 - 118,835,030UniSTSGRCm38
MGSCv371120,731,316 - 120,731,607UniSTSGRCm37
Celera1121,494,790 - 121,495,081UniSTS
Cytogenetic Map1E2-E4UniSTS
cM Map163.0UniSTS
AW546128  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381118,834,568 - 118,834,665UniSTSGRCm38
MGSCv371120,731,145 - 120,731,242UniSTSGRCm37
Celera1121,494,619 - 121,494,716UniSTS
Cytogenetic Map1E2-E4UniSTS
Whitehead/MRC_RH11611.83UniSTS
D1Mit189  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381118,982,324 - 118,982,471UniSTSGRCm38
MGSCv371120,878,901 - 120,879,048UniSTSGRCm37
Celera1121,642,704 - 121,642,845UniSTS
Cytogenetic Map1E2-E4UniSTS
cM Map163.1UniSTS
Whitehead Genetic166.7UniSTS
Whitehead_YAC1 UniSTS
D1Mit367  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381118,911,488 - 118,911,613UniSTSGRCm38
MGSCv371120,808,065 - 120,808,190UniSTSGRCm37
Celera1121,571,774 - 121,571,897UniSTS
Cytogenetic Map1E2-E4UniSTS
cM Map163.1UniSTS
Whitehead Genetic166.7UniSTS
Whitehead_YAC1 UniSTS
D1Mit368  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381118,911,488 - 118,911,605UniSTSGRCm38
MGSCv371120,808,065 - 120,808,182UniSTSGRCm37
Celera1121,571,774 - 121,571,889UniSTS
Cytogenetic Map1E2-E4UniSTS
cM Map163.1UniSTS
Whitehead Genetic166.7UniSTS
Whitehead_YAC1 UniSTS
Gli2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381118,842,915 - 118,843,005UniSTSGRCm38
MGSCv371120,739,492 - 120,739,582UniSTSGRCm37
Celera1121,502,973 - 121,503,081UniSTS
Cytogenetic Map1E2-E4UniSTS
cM Map163.0UniSTS
Gli2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381118,854,481 - 118,855,537UniSTSGRCm38
MGSCv371120,751,058 - 120,752,114UniSTSGRCm37
Celera1121,514,563 - 121,515,620UniSTS
Cytogenetic Map1E2-E4UniSTS
Gli2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1E2-E4UniSTS
Gli2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1E2-E4UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001081125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC109271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM261668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM261669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM261670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM262741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM262742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM262743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM262744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC082604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ102399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X99104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000062483   ⟹   ENSMUSP00000054837
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1118,761,862 - 118,981,349 (-)Ensembl
GRCm38.p6 Ensembl1118,834,132 - 119,053,619 (-)Ensembl
Ensembl Acc Id: ENSMUST00000159678
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1118,795,772 - 118,910,318 (-)Ensembl
GRCm38.p6 Ensembl1118,868,042 - 118,982,588 (-)Ensembl
Ensembl Acc Id: ENSMUST00000159839   ⟹   ENSMUSP00000125661
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1118,776,190 - 118,981,069 (-)Ensembl
GRCm38.p6 Ensembl1118,848,460 - 119,053,339 (-)Ensembl
Ensembl Acc Id: ENSMUST00000160991   ⟹   ENSMUSP00000125634
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1118,776,190 - 118,981,069 (-)Ensembl
GRCm38.p6 Ensembl1118,848,460 - 119,053,339 (-)Ensembl
Ensembl Acc Id: ENSMUST00000161056   ⟹   ENSMUSP00000124768
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1118,776,190 - 118,981,069 (-)Ensembl
GRCm38.p6 Ensembl1118,848,460 - 119,053,339 (-)Ensembl
Ensembl Acc Id: ENSMUST00000161301   ⟹   ENSMUSP00000125342
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1118,776,190 - 118,981,069 (-)Ensembl
GRCm38.p6 Ensembl1118,848,460 - 119,053,339 (-)Ensembl
Ensembl Acc Id: ENSMUST00000161451   ⟹   ENSMUSP00000124132
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1118,776,192 - 118,981,069 (-)Ensembl
GRCm38.p6 Ensembl1118,848,462 - 119,053,339 (-)Ensembl
Ensembl Acc Id: ENSMUST00000162552   ⟹   ENSMUSP00000125059
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1118,776,190 - 118,981,069 (-)Ensembl
GRCm38.p6 Ensembl1118,848,460 - 119,053,339 (-)Ensembl
Ensembl Acc Id: ENSMUST00000162607   ⟹   ENSMUSP00000123808
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1118,776,192 - 118,981,069 (-)Ensembl
GRCm38.p6 Ensembl1118,848,462 - 119,053,339 (-)Ensembl
RefSeq Acc Id: NM_001081125   ⟹   NP_001074594
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391118,761,791 - 118,981,349 (-)NCBI
GRCm381118,834,061 - 119,053,619 (-)NCBI
MGSCv371120,730,638 - 120,950,196 (-)RGD
Celera1121,494,112 - 121,713,823 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006529141   ⟹   XP_006529204
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391118,761,858 - 118,910,800 (-)NCBI
GRCm381118,834,128 - 118,983,070 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011247924   ⟹   XP_011246226
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391118,761,858 - 118,892,479 (-)NCBI
GRCm381118,834,128 - 118,964,753 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248278   ⟹   XP_030104138
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391118,761,858 - 118,982,127 (-)NCBI
GRCm381118,834,128 - 119,054,405 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160446   ⟹   XP_036016339
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391118,761,858 - 118,910,800 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160464   ⟹   XP_036016357
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391118,761,858 - 118,982,123 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160484   ⟹   XP_036016377
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391118,761,858 - 118,982,123 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160522   ⟹   XP_036016415
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391118,761,858 - 118,987,578 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001074594   ⟸   NM_001081125
- UniProtKB: E9PYJ4 (UniProtKB/Swiss-Prot),   Q0VGT2 (UniProtKB/Swiss-Prot),   Q0VGV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006529204   ⟸   XM_006529141
- Peptide Label: isoform X2
- UniProtKB: Q0VGV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011246226   ⟸   XM_011247924
- Peptide Label: isoform X2
- UniProtKB: Q0VGV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030104138   ⟸   XM_030248278
- Peptide Label: isoform X1
- UniProtKB: Q0VGT2 (UniProtKB/Swiss-Prot),   E9PYJ4 (UniProtKB/Swiss-Prot),   Q0VGV1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000125661   ⟸   ENSMUST00000159839
Ensembl Acc Id: ENSMUSP00000125634   ⟸   ENSMUST00000160991
Ensembl Acc Id: ENSMUSP00000054837   ⟸   ENSMUST00000062483
Ensembl Acc Id: ENSMUSP00000123808   ⟸   ENSMUST00000162607
Ensembl Acc Id: ENSMUSP00000125059   ⟸   ENSMUST00000162552
Ensembl Acc Id: ENSMUSP00000125342   ⟸   ENSMUST00000161301
Ensembl Acc Id: ENSMUSP00000124132   ⟸   ENSMUST00000161451
Ensembl Acc Id: ENSMUSP00000124768   ⟸   ENSMUST00000161056
RefSeq Acc Id: XP_036016415   ⟸   XM_036160522
- Peptide Label: isoform X4
- UniProtKB: Q0VGV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016377   ⟸   XM_036160484
- Peptide Label: isoform X3
- UniProtKB: Q0VGV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016357   ⟸   XM_036160464
- Peptide Label: isoform X3
- UniProtKB: Q0VGV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016339   ⟸   XM_036160446
- Peptide Label: isoform X2
- UniProtKB: Q0VGV1 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q0VGT2-F1-model_v2 AlphaFold Q0VGT2 1-1544 view protein structure

Promoters
RGD ID:6874702
Promoter ID:EPDNEW_M802
Type:multiple initiation site
Name:Gli2_1
Description:Mus musculus GLI-Kruppel family member GLI2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381119,053,546 - 119,053,606EPDNEW
RGD ID:6817751
Promoter ID:MM_KWN:1873
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   ES_Cell
Transcripts:NM_001081125,   UC007CIN.1,   UC007CIO.1,   UC007CIP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361120,949,761 - 120,950,261 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95728 AgrOrtholog
Ensembl Genes ENSMUSG00000048402 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000062483 ENTREZGENE
  ENSMUST00000062483.15 UniProtKB/Swiss-Prot
  ENSMUST00000159839.8 UniProtKB/TrEMBL
  ENSMUST00000160991.8 UniProtKB/TrEMBL
  ENSMUST00000161056.8 UniProtKB/TrEMBL
  ENSMUST00000161301.8 UniProtKB/TrEMBL
  ENSMUST00000161451.8 UniProtKB/TrEMBL
  ENSMUST00000162552.8 UniProtKB/TrEMBL
  ENSMUST00000162607.2 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GLI-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14633 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95728 ENTREZGENE
NCBI Gene 14633 ENTREZGENE
PANTHER PTHR45718 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC FINGER PROTEIN GLI2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gli2 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1B0GXK7_MOUSE UniProtKB/TrEMBL
  A5A9W3_MOUSE UniProtKB/TrEMBL
  A5A9W4_MOUSE UniProtKB/TrEMBL
  A5A9W5_MOUSE UniProtKB/TrEMBL
  A5AA25_MOUSE UniProtKB/TrEMBL
  A5AA26_MOUSE UniProtKB/TrEMBL
  A5AA27_MOUSE UniProtKB/TrEMBL
  E9PYJ4 ENTREZGENE
  F6UUE3_MOUSE UniProtKB/TrEMBL
  GLI2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q0VGV1 ENTREZGENE, UniProtKB/TrEMBL
  Q8BKI7_MOUSE UniProtKB/TrEMBL
  Q8K0K3_MOUSE UniProtKB/TrEMBL
UniProt Secondary A0A0A6YYN1 UniProtKB/TrEMBL
  A0A0K0K1C7 UniProtKB/TrEMBL
  E9PYJ4 UniProtKB/Swiss-Prot
  F6TWE5 UniProtKB/TrEMBL