Ccl12 (C-C motif chemokine ligand 12) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ccl12 (C-C motif chemokine ligand 12) Mus musculus
Analyze
Symbol: Ccl12
Name: C-C motif chemokine ligand 12
RGD ID: 1319498
MGI Page MGI
Description: Enables CCR2 chemokine receptor binding activity. Involved in angiogenesis; inflammatory response; and monocyte chemotaxis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; aggressive periodontitis; autoimmune disease (multiple); end stage renal disease; and gastrointestinal system cancer (multiple). Orthologous to human CCL2 (C-C motif chemokine ligand 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C-C motif chemokine 12; chemokine (C-C motif) ligand 12; MCP-; MCP-1-related chemokine; MCP-5; monocyte chemoattractant protein 5; monocyte chemotactic protein 5; Scya; Scya12; small inducible cytokine A12; small-inducible cytokine A12
RGD Orthologs
Human
Rat
Bonobo
Dog
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391181,992,671 - 81,994,225 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1181,992,671 - 81,994,226 (+)EnsemblGRCm39 Ensembl
GRCm381182,101,845 - 82,103,399 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1182,101,845 - 82,103,400 (+)EnsemblGRCm38mm10GRCm38
MGSCv371181,915,347 - 81,916,901 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361181,918,073 - 81,919,486 (+)NCBIMGSCv36mm8
Celera1186,814,429 - 86,815,983 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1149.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1-chloro-2,4-dinitrobenzene  (EXP)
1-octadec-9-enoylglycero-3-phosphate  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
acetamide  (ISO)
acrylamide  (ISO)
alpha-Zearalanol  (ISO)
amphibole asbestos  (ISO)
antirheumatic drug  (ISO)
asperentin  (EXP)
benzo[a]pyrene  (EXP,ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
Brevianamide A  (EXP)
C60 fullerene  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (EXP,ISO)
chlorpyrifos  (EXP)
cisplatin  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
deoxynivalenol  (EXP)
dexamethasone  (EXP,ISO)
dichlorine  (EXP)
doxorubicin  (EXP,ISO)
edaravone  (ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
eugenol  (ISO)
fenofibrate  (ISO)
fragrance  (ISO)
genistein  (EXP)
hexanal  (ISO)
indometacin  (ISO)
lead diacetate  (EXP)
leukotriene B4  (EXP)
leukotriene C4  (EXP)
lipopolysaccharide  (EXP)
mercury atom  (EXP)
mercury(0)  (EXP)
methamphetamine  (ISO)
methotrexate  (ISO)
methylmercury chloride  (EXP,ISO)
mifepristone  (ISO)
MK 571  (EXP)
mycotoxin  (EXP)
naphthalene  (EXP)
neoechinulin A  (EXP)
nickel atom  (ISO)
nickel dichloride  (EXP)
nickel sulfate  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (EXP)
paraquat  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
potassium dichromate  (EXP)
pravastatin  (EXP,ISO)
prednisone  (ISO)
prostaglandin E2  (EXP)
quercetin  (EXP,ISO)
resveratrol  (EXP)
serpentine asbestos  (EXP)
silicon dioxide  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
TMC-120A  (EXP)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
trichloroethene  (ISO)
troglitazone  (ISO)
zaragozic acid A  (EXP,ISO)
zileuton  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Increased presence of dendritic cells and dendritic cell chemokines in the sinus mucosa of chronic rhinosinusitis with nasal polyps and allergic fungal rhinosinusitis. Ayers CM, etal., Int Forum Allergy Rhinol. 2011 Jul-Aug;1(4):296-302. doi: 10.1002/alr.20046. Epub 2011 Apr 11.
2. MCP-1 and CCR2 gene variants in oral squamous cell carcinoma. Bektas-Kayhan K, etal., Oral Dis. 2012 Jan;18(1):55-9. doi: 10.1111/j.1601-0825.2011.01843.x. Epub 2011 Aug 24.
3. CCR2-64I gene polymorphism increase susceptibility to oral cancer. Chen MK, etal., Oral Oncol. 2011 Jul;47(7):577-82. doi: 10.1016/j.oraloncology.2011.04.008. Epub 2011 May 12.
4. MCP-1, CCR2 and CCR5 polymorphisms in Tunisian patients with atopic asthma. Dhaouadi T, etal., Iran J Allergy Asthma Immunol. 2013 Mar;12(1):29-36. doi: 012.01/ijaai.2936.
5. Hepatocyte-Specific Arid1a Deficiency Initiates Mouse Steatohepatitis and Hepatocellular Carcinoma. Fang JZ, etal., PLoS One. 2015 Nov 16;10(11):e0143042. doi: 10.1371/journal.pone.0143042. eCollection 2015.
6. Serum chemokine and cytokine levels as indicators of disease activity in patients with systemic sclerosis. Hasegawa M, etal., Clin Rheumatol. 2011 Feb;30(2):231-7. Epub 2010 Nov 4.
7. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
8. Selective chemokine mRNA accumulation in the rat spinal cord after contusion injury. McTigue DM, etal., J Neurosci Res. 1998 Aug 1;53(3):368-76.
9. MGDs mouse GO annotations MGD data from the GO Consortium
10. Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis. Ockinger J, etal., Genes Immun. 2010 Mar;11(2):142-54. Epub 2009 Oct 29.
11. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
12. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice. Sennlaub F, etal., EMBO Mol Med. 2013 Nov;5(11):1775-93. doi: 10.1002/emmm.201302692. Epub 2013 Oct 21.
16. Differential expression of chemokines and chemokine receptors in inflammatory periapical diseases. Silva TA, etal., Oral Microbiol Immunol. 2005 Oct;20(5):310-6.
17. Proinflammatory gene expression at chronic periodontitis and peri-implantitis sites in patients with or without type 2 diabetes. Venza I, etal., J Periodontol. 2010 Jan;81(1):99-108. doi: 10.1902/jop.2009.090358.
18. Chemokine gene polymorphisms in idiopathic anterior uveitis. Yeo TK, etal., Cytokine. 2006 Jul;35(1-2):29-35. Epub 2006 Sep 6.
19. Combined association of CCR2-V64I and MCP-1-2518A/G polymorphisms with generalised aggressive periodontitis in Chinese. Zhu XL, etal., Chin J Dent Res. 2010;13(2):109-14.
Additional References at PubMed
PMID:8920881   PMID:8996246   PMID:10349636   PMID:10438970   PMID:10995569   PMID:11042159   PMID:11076861   PMID:11735217   PMID:12080938   PMID:12477932   PMID:15489334   PMID:16141072  
PMID:16141073   PMID:16602821   PMID:17364026   PMID:18334747   PMID:20234092   PMID:20931267   PMID:21217759   PMID:21677750   PMID:21873635   PMID:22814601   PMID:23033370   PMID:24458145  
PMID:24477914   PMID:25495686   PMID:25526093   PMID:27181207   PMID:27626662   PMID:27965054   PMID:31922885   PMID:33160071   PMID:35260907   PMID:37012245   PMID:38395995   PMID:39395421  


Genomics

Comparative Map Data
Ccl12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391181,992,671 - 81,994,225 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1181,992,671 - 81,994,226 (+)EnsemblGRCm39 Ensembl
GRCm381182,101,845 - 82,103,399 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1182,101,845 - 82,103,400 (+)EnsemblGRCm38mm10GRCm38
MGSCv371181,915,347 - 81,916,901 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361181,918,073 - 81,919,486 (+)NCBIMGSCv36mm8
Celera1186,814,429 - 86,815,983 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1149.9NCBI
CCL13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381734,356,480 - 34,358,610 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1734,356,480 - 34,358,610 (+)EnsemblGRCh38hg38GRCh38
GRCh371732,683,499 - 32,685,629 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361729,707,584 - 29,709,742 (+)NCBINCBI36Build 36hg18NCBI36
Build 341729,707,583 - 29,709,741NCBI
Celera1729,593,701 - 29,595,859 (+)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1728,869,568 - 28,871,726 (+)NCBIHuRef
CHM1_11732,747,735 - 32,749,893 (+)NCBICHM1_1
T2T-CHM13v2.01735,303,463 - 35,305,593 (+)NCBIT2T-CHM13v2.0
Ccl12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81067,567,876 - 67,569,426 (+)NCBIGRCr8
mRatBN7.21067,070,230 - 67,071,780 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1067,070,230 - 67,071,780 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1071,691,474 - 71,693,024 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01071,196,825 - 71,198,375 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01066,657,944 - 66,659,494 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01069,476,866 - 69,478,416 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1069,476,775 - 69,478,462 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01069,111,876 - 69,113,426 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41070,321,036 - 70,322,586NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1066,017,637 - 66,019,187 (+)NCBICelera
Cytogenetic Map10q26NCBI
CCL13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21930,110,619 - 30,120,918 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11731,991,689 - 32,002,241 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01722,430,633 - 22,432,893 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11722,724,145 - 22,726,306 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1722,723,888 - 22,726,381 (-)Ensemblpanpan1.1panPan2
CCL13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1938,938,944 - 38,940,231 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl938,938,135 - 38,940,231 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha938,162,012 - 38,163,300 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0939,752,155 - 39,753,443 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl939,728,462 - 39,769,550 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1938,539,350 - 38,540,637 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0938,818,831 - 38,820,119 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0938,907,308 - 38,908,596 (-)NCBIUU_Cfam_GSD_1.0
CCL13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11627,864,260 - 27,867,457 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1627,865,318 - 27,867,415 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660752,152,140 - 2,154,842 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Ccl12
38 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:189
Count of miRNA genes:156
Interacting mature miRNAs:168
Transcripts:ENSMUST00000000194, ENSMUST00000124916
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117373754182069425Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117757387399377820Mouse

Markers in Region
U50712  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381182,103,247 - 82,103,393UniSTSGRCm38
MGSCv371181,916,749 - 81,916,895UniSTSGRCm37
Celera1187,127,152 - 87,127,298UniSTS
Celera1186,815,831 - 86,815,977UniSTS
Cytogenetic Map11CUniSTS
cM Map1147.0UniSTS
Whitehead/MRC_RH111043.27UniSTS
Scya12  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381182,102,827 - 82,103,134UniSTSGRCm38
MGSCv371181,916,329 - 81,916,636UniSTSGRCm37
Celera1187,126,732 - 87,127,039UniSTS
Celera1186,815,411 - 86,815,718UniSTS
Cytogenetic Map11CUniSTS
cM Map1147.0UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000000194   ⟹   ENSMUSP00000000194
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1181,992,671 - 81,994,226 (+)Ensembl
GRCm38.p6 Ensembl1182,101,845 - 82,103,400 (+)Ensembl
Ensembl Acc Id: ENSMUST00000124916
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1181,992,678 - 81,994,193 (+)Ensembl
GRCm38.p6 Ensembl1182,101,852 - 82,103,367 (+)Ensembl
RefSeq Acc Id: NM_011331   ⟹   NP_035461
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391181,992,671 - 81,994,225 (+)NCBI
GRCm381182,101,845 - 82,103,399 (+)ENTREZGENE
MGSCv371181,915,347 - 81,916,901 (+)RGD
Celera1187,125,750 - 87,127,304 (+)NCBI
Celera1186,814,429 - 86,815,983 (+)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_035461   ⟸   NM_011331
- Peptide Label: precursor
- UniProtKB: Q9QYD6 (UniProtKB/Swiss-Prot),   Q62401 (UniProtKB/Swiss-Prot),   Q545B5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000000194   ⟸   ENSMUST00000000194
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62401-F1-model_v2 AlphaFold Q62401 1-104 view protein structure

Promoters
RGD ID:6820567
Promoter ID:MM_KWN:8835
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:OTTMUST00000001671,   OTTMUST00000001672
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361181,915,294 - 81,915,794 (+)MPROMDB
RGD ID:8675828
Promoter ID:EPDNEW_M15944
Type:multiple initiation site
Name:Ccl12_1
Description:Mus musculus chemokine (C-C motif) ligand 12 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381182,101,845 - 82,101,905EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:108224 AgrOrtholog
Ensembl Genes ENSMUSG00000035352 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000000194 ENTREZGENE
  ENSMUST00000000194.4 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.50.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Chemokine_b/g/d UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_CC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20293 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:108224 ENTREZGENE
NCBI Gene 20293 ENTREZGENE
PANTHER C-C MOTIF CHEMOKINE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12015 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ccl12 PhenoGen
PROSITE SMALL_CYTOKINES_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SCY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CCL12_MOUSE UniProtKB/Swiss-Prot
  Q545B5 ENTREZGENE, UniProtKB/TrEMBL
  Q62401 ENTREZGENE
  Q9QYD6 ENTREZGENE
UniProt Secondary Q9QYD6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-04 Ccl12  C-C motif chemokine ligand 12  Ccl12  chemokine (C-C motif) ligand 12  Symbol and/or name change 5135510 APPROVED