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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | DTD2 | Human | (+)-schisandrin B | multiple interactions | ISO | Dtd2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of DTD2 mRNA] | CTD | PMID:31150632 | DTD2 | Human | (-)-epigallocatechin 3-gallate | multiple interactions | EXP | | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DTD2 mRNA | CTD | PMID:22079256 | DTD2 | Human | 1,2-dimethylhydrazine | multiple interactions | ISO | Dtd2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DTD2 mRNA | CTD | PMID:22206623 | DTD2 | Human | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of DTD2 mRNA | CTD | PMID:33167477 | DTD2 | Human | arsane | affects methylation | EXP | | 6480464 | Arsenic affects the methylation of DTD2 gene | CTD | PMID:25304211 | DTD2 | Human | arsenic atom | affects methylation | EXP | | 6480464 | Arsenic affects the methylation of DTD2 gene | CTD | PMID:25304211 | DTD2 | Human | arsenite(3-) | increases expression | ISO | Dtd2 (Mus musculus) | 6480464 | arsenite results in increased expression of DTD2 protein | CTD | PMID:37955338 | DTD2 | Human | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of DTD2 promoter | CTD | PMID:27901495 | DTD2 | Human | benzo[e]pyrene | increases methylation | EXP | | 6480464 | benzo(e)pyrene results in increased methylation of DTD2 intron | CTD | PMID:30157460 | DTD2 | Human | bisphenol A | decreases expression | ISO | Dtd2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of DTD2 mRNA | CTD | PMID:25181051 and PMID:34947998 | DTD2 | Human | copper(II) sulfate | decreases expression | EXP | | 6480464 | Copper Sulfate results in decreased expression of DTD2 mRNA | CTD | PMID:19549813 | DTD2 | Human | Dibutyl phosphate | affects expression | EXP | | 6480464 | di-n-butylphosphoric acid affects the expression of DTD2 mRNA | CTD | PMID:37042841 | DTD2 | Human | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | DTD2 | Human | ethyl methanesulfonate | decreases expression | EXP | | 6480464 | Ethyl Methanesulfonate results in decreased expression of DTD2 mRNA | CTD | PMID:23649840 | DTD2 | Human | flutamide | decreases expression | ISO | Dtd2 (Rattus norvegicus) | 6480464 | Flutamide results in decreased expression of DTD2 mRNA | CTD | PMID:24793618 | DTD2 | Human | folic acid | multiple interactions | ISO | Dtd2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DTD2 mRNA | CTD | PMID:22206623 | DTD2 | Human | formaldehyde | decreases expression | EXP | | 6480464 | Formaldehyde results in decreased expression of DTD2 mRNA | CTD | PMID:23649840 | DTD2 | Human | gentamycin | decreases expression | ISO | Dtd2 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of DTD2 mRNA | CTD | PMID:33387578 | DTD2 | Human | inulin | multiple interactions | ISO | Dtd2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of DTD2 mRNA | CTD | PMID:36331819 | DTD2 | Human | methapyrilene | increases methylation | EXP | | 6480464 | Methapyrilene results in increased methylation of DTD2 intron | CTD | PMID:30157460 | DTD2 | Human | methyl methanesulfonate | decreases expression | EXP | | 6480464 | Methyl Methanesulfonate results in decreased expression of DTD2 mRNA | CTD | PMID:23649840 | DTD2 | Human | oxaliplatin | multiple interactions | ISO | Dtd2 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of DTD2 mRNA | CTD | PMID:25729387 | DTD2 | Human | oxaliplatin | decreases expression | ISO | Dtd2 (Rattus norvegicus) | 6480464 | oxaliplatin results in decreased expression of DTD2 mRNA | CTD | PMID:25729387 | DTD2 | Human | paracetamol | increases expression | ISO | Dtd2 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of DTD2 mRNA | CTD | PMID:33387578 | DTD2 | Human | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Dtd2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of DTD2 mRNA | CTD | PMID:36331819 | DTD2 | Human | potassium chromate | multiple interactions | EXP | | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DTD2 mRNA | CTD | PMID:22079256 | DTD2 | Human | potassium chromate | decreases expression | EXP | | 6480464 | potassium chromate(VI) results in decreased expression of DTD2 mRNA | CTD | PMID:22079256 | DTD2 | Human | quercetin | decreases expression | EXP | | 6480464 | Quercetin results in decreased expression of DTD2 mRNA | CTD | PMID:21632981 | DTD2 | Human | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | DTD2 | Human | tetrachloromethane | decreases expression | ISO | Dtd2 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of DTD2 mRNA | CTD | PMID:31150632 | DTD2 | Human | tetrachloromethane | multiple interactions | ISO | Dtd2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of DTD2 mRNA] | CTD | PMID:31150632 | DTD2 | Human | thioacetamide | decreases expression | ISO | Dtd2 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of DTD2 mRNA | CTD | PMID:34492290 | DTD2 | Human | thiram | decreases expression | EXP | | 6480464 | Thiram results in decreased expression of DTD2 mRNA | CTD | PMID:38568856 | DTD2 | Human | topotecan | multiple interactions | ISO | Dtd2 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of DTD2 mRNA | CTD | PMID:25729387 | DTD2 | Human | topotecan | decreases expression | ISO | Dtd2 (Rattus norvegicus) | 6480464 | Topotecan results in decreased expression of DTD2 mRNA | CTD | PMID:25729387 | DTD2 | Human | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of DTD2 mRNA | CTD | PMID:24935251 and PMID:26272509 | DTD2 | Human | trichostatin A | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DTD2 mRNA | CTD | PMID:27188386 | DTD2 | Human | triphenyl phosphate | affects expression | EXP | | 6480464 | triphenyl phosphate affects the expression of DTD2 mRNA | CTD | PMID:37042841 | DTD2 | Human | urethane | decreases expression | EXP | | 6480464 | Urethane results in decreased expression of DTD2 mRNA | CTD | PMID:28818685 | DTD2 | Human | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of DTD2 mRNA | CTD | PMID:25979313 | DTD2 | Human | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of DTD2 mRNA | CTD | PMID:23179753 and PMID:26272509 | DTD2 | Human | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DTD2 mRNA | CTD | PMID:27188386 | DTD2 | Human | vorinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DTD2 mRNA | CTD | PMID:27188386 | |