Stat6 (signal transducer and activator of transcription 6) - Rat Genome Database

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Gene: Stat6 (signal transducer and activator of transcription 6) Mus musculus
Analyze
Symbol: Stat6
Name: signal transducer and activator of transcription 6
RGD ID: 1319195
MGI Page MGI
Description: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in gene expression; interleukin-4-mediated signaling pathway; and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including T-helper 1 cell lineage commitment; mammary gland development; and regulation of nucleobase-containing compound metabolic process. Located in chromatin; cytoplasm; and nucleus. Is expressed in several structures, including 2-cell stage embryo; lower urinary tract; male reproductive system; olfactory epithelium; and submandibular gland primordium. Human ortholog(s) of this gene implicated in colon adenocarcinoma; lipoid nephrosis; prostate carcinoma; rectum adenocarcinoma; and urinary schistosomiasis. Orthologous to human STAT6 (signal transducer and activator of transcription 6).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: signal transducer and transcription activator 6
RGD Orthologs
Human
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,478,855 - 127,496,856 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,478,855 - 127,496,826 (+)EnsemblGRCm39 Ensembl
GRCm3810127,642,955 - 127,660,987 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,642,986 - 127,660,957 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710127,080,042 - 127,098,043 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610127,046,120 - 127,063,352 (+)NCBIMGSCv36mm8
Celera10130,035,284 - 130,053,348 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (EXP)
1,4-dithiothreitol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxynon-2-enal  (ISO)
4-tert-Octylphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
alpinumisoflavone  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bleomycin A2  (EXP)
caffeine  (ISO)
calcitriol  (ISO)
calcium dichloride  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP,ISO)
carboplatin  (EXP)
CGP 52608  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyfluthrin  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
Diisodecyl phthalate  (EXP)
donepezil hydrochloride  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
Fidarestat  (EXP,ISO)
flavonoids  (ISO)
fluorescein 5-isothiocyanate  (EXP)
flutamide  (EXP,ISO)
geraniol  (ISO)
glycidol  (ISO)
histamine  (ISO)
hydrogen peroxide  (EXP,ISO)
ivermectin  (ISO)
ketorolac  (ISO)
L-1,4-dithiothreitol  (EXP)
L-ascorbic acid  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (EXP)
lidocaine  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
mechlorethamine  (EXP)
melatonin  (EXP)
mercury dichloride  (ISO)
methamphetamine  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
morphine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nicotine  (ISO)
oxaliplatin  (EXP,ISO)
ozone  (ISO)
p-tert-Amylphenol  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
perfluorooctanoic acid  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP,ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
rimonabant  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
serpentine asbestos  (EXP)
simvastatin  (EXP)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
Sodium salicylate  (ISO)
sunitinib  (ISO)
synephrine  (EXP)
tamoxifen  (EXP)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
thioacetamide  (ISO)
thymoquinone  (EXP)
tofacitinib  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
triptonide  (EXP)
tungsten  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal acute inflammation  (IAGP)
abnormal airway responsiveness  (IAGP)
abnormal B cell physiology  (IAGP)
abnormal B cell proliferation  (IAGP)
abnormal CD4-positive T cell differentiation  (IAGP)
abnormal CD8-positive, alpha beta T cell morphology  (IAGP)
abnormal circulating alanine transaminase level  (IAGP)
abnormal circulating histamine level  (IAGP)
abnormal circulating interleukin level  (IAGP)
abnormal circulating interleukin-4 level  (IAGP)
abnormal circulating interleukin-5 level  (IAGP)
abnormal class switch recombination  (IAGP)
abnormal conjunctival epithelium morphology  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal cytotoxic T cell physiology  (IAGP)
abnormal granulocyte physiology  (IAGP)
abnormal humoral immune response  (IAGP)
abnormal immune serum protein physiology  (IAGP)
abnormal immunoglobulin level  (IAGP)
abnormal interleukin secretion  (IAGP)
abnormal leukocyte migration  (IAGP)
abnormal leukocyte physiology  (IAGP)
abnormal level of surface class II molecules  (IAGP)
abnormal lung morphology  (IAGP)
abnormal lung size  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal mammary gland epithelium morphology  (IAGP)
abnormal mammary gland growth during pregnancy  (IAGP)
abnormal mammary gland morphology  (IAGP)
abnormal mast cell morphology  (IAGP)
abnormal noradrenaline level  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal renal tubule morphology  (IAGP)
abnormal respiratory epithelium morphology  (IAGP)
abnormal respiratory system morphology  (IAGP)
abnormal respiratory system physiology  (IAGP)
abnormal T-helper 1 cell differentiation  (IAGP)
abnormal T-helper 2 cell differentiation  (IAGP)
abnormal T-helper 2 physiology  (IAGP)
abnormal tumor susceptibility  (IAGP)
acanthosis  (IAGP)
blepharitis  (IAGP)
decreased B cell proliferation  (IAGP)
decreased body size  (IAGP)
decreased core body temperature  (IAGP)
decreased fatty acids level  (IAGP)
decreased IgA level  (IAGP)
decreased IgE level  (IAGP)
decreased IgG1 level  (IAGP)
decreased IgG3 level  (IAGP)
decreased IgM level  (IAGP)
decreased interleukin-4 secretion  (IAGP)
decreased interleukin-5 secretion  (IAGP)
decreased mammary gland epithelial cell proliferation  (IAGP)
decreased metastatic potential  (IAGP)
decreased susceptibility to autoimmune diabetes  (IAGP)
decreased susceptibility to Herpesvirales infection  (IAGP)
decreased T cell proliferation  (IAGP)
decreased T-helper 2 cell number  (IAGP)
dermatitis  (IAGP)
emphysema  (IAGP)
enlarged liver  (IAGP)
epidermal hyperplasia  (IAGP)
excessive scratching  (IAGP)
eye inflammation  (IAGP)
hyperkeratosis  (IAGP)
impaired eosinophil chemotaxis  (IAGP)
impaired eosinophil recruitment  (IAGP)
impaired neutrophil chemotaxis  (IAGP)
increased activated T cell number  (IAGP)
increased B cell apoptosis  (IAGP)
increased cellular sensitivity to gamma-irradiation  (IAGP)
increased circulating creatine level  (IAGP)
increased circulating interferon-gamma level  (IAGP)
increased circulating interleukin-18 level  (IAGP)
increased circulating tumor necrosis factor level  (IAGP)
increased eosinophil cell number  (IAGP)
increased IgA level  (IAGP)
increased IgE level  (IAGP)
increased IgG level  (IAGP)
increased IgG1 level  (IAGP)
increased IgG2a level  (IAGP)
increased interferon-gamma secretion  (IAGP)
increased interleukin-12 secretion  (IAGP)
increased interleukin-2 secretion  (IAGP)
increased susceptibility to autoimmune diabetes  (IAGP)
increased susceptibility to parasitic infection  (IAGP)
lethality at weaning, complete penetrance  (IAGP)
liver inflammation  (IAGP)
overexpanded pulmonary alveolus  (IAGP)
postnatal growth retardation  (IAGP)
premature death  (IAGP)
respiratory system inflammation  (IAGP)
skin edema  (IAGP)
skin inflammation  (IAGP)
skin lesions  (IAGP)
thymus atrophy  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Polymorphism of the interleukin-4, interleukin-13, and signal transducer and activator of transcription 6 genes in Indonesian children with minimal change nephrotic syndrome. Acharya B, etal., Am J Nephrol. 2005 Jan-Feb;25(1):30-5. Epub 2005 Feb 1.
2. Signal transducer and activator of transcription-6 (STAT6) is a constitutively expressed survival factor in human prostate cancer. Das S, etal., Prostate. 2007 Oct 1;67(14):1550-64.
3. Identification of immune checkpoint inhibitors and biomarkers among STAT family in stomach adenocarcinoma. Guo L, etal., Am J Transl Res. 2020 Sep 15;12(9):4977-4997. eCollection 2020.
4. A STAT6 gene polymorphism is associated with high infection levels in urinary schistosomiasis. He H, etal., Genes Immun. 2008 Apr;9(3):195-206. doi: 10.1038/gene.2008.2. Epub 2008 Feb 14.
5. Polymorphisms in interleukin-4-related genes in patients with minimal change nephrotic syndrome. Ikeuchi Y, etal., Pediatr Nephrol. 2009 Mar;24(3):489-95. doi: 10.1007/s00467-008-1003-y. Epub 2008 Nov 15.
6. Pivotal role of Stat4 and Stat6 in the pathogenesis of the lupus-like disease in the New Zealand mixed 2328 mice. Jacob CO, etal., J Immunol. 2003 Aug 1;171(3):1564-71.
7. Polymorphisms of interleukin-4--related genes in Japanese children with minimal change nephrotic syndrome. Kobayashi Y, etal., Am J Kidney Dis. 2003 Aug;42(2):271-6.
8. Signal transducer and activator of transcription (Stat)-6-dependent, but not Stat4-dependent, immunity is required for the development of autoimmunity in Graves' hyperthyroidism. Land KJ, etal., Endocrinology. 2004 Aug;145(8):3724-30. Epub 2004 Apr 29.
9. Loss of STAT6 promotes autoimmune disease and atopy on a susceptible genetic background. Lau M, etal., J Autoimmun. 2012 Dec;39(4):388-97. doi: 10.1016/j.jaut.2012.06.003. Epub 2012 Aug 4.
10. [Expression of signal transducer and activator of transcription 6 in rat asthma model and the modulatory effect of dexamethasone]. Li CC, etal., Zhonghua Er Ke Za Zhi. 2005 Jul;43(7):521-5.
11. [Effects of interleukin 1 receptor antagonist on allergy asthma in rat model and its mechanism]. Liu ZC, etal., Zhonghua Yi Xue Za Zhi. 2008 Sep 9;88(34):2432-6.
12. Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease. Low SH, etal., Dev Cell. 2006 Jan;10(1):57-69.
13. Pivotal role of signal transducer and activator of transcription (Stat)4 and Stat6 in the innate immune response during sepsis. Matsukawa A, etal., J Exp Med. 2001 Mar 19;193(6):679-88.
14. MGDs mouse GO annotations MGD data from the GO Consortium
15. MGD IEA MGD IEA
16. The JAK-STAT signaling pathway: input and output integration. Murray PJ J Immunol. 2007 Mar 1;178(5):2623-9.
17. Selective activation of members of the signal transducers and activators of transcription family in prostate carcinoma. Ni Z, etal., J Urol. 2002 Apr;167(4):1859-62.
18. Signal transducer and activator of transcription-6 (STAT6) inhibition suppresses renal cyst growth in polycystic kidney disease. Olsan EE, etal., Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18067-72. doi: 10.1073/pnas.1111966108. Epub 2011 Oct 24.
19. A role for T helper 2 cells in mediating skin fibrosis in tight-skin mice. Ong CJ, etal., Cell Immunol. 1999 Aug 25;196(1):60-8.
20. Cutting edge: STAT6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma. Ostrand-Rosenberg S, etal., J Immunol. 2000 Dec 1;165(11):6015-9.
21. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
22. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
23. Mouse MP Annotation Import Pipeline RGD automated import pipeline
24. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
25. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
26. JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. Slattery ML, etal., Mol Carcinog. 2013 Feb;52(2):155-66. doi: 10.1002/mc.21841. Epub 2011 Nov 28.
27. Signal transducer and activation of transcription 6 (STAT6) regulates T helper type 1 (Th1) and Th17 nephritogenic immunity in experimental crescentic glomerulonephritis. Summers SA, etal., Clin Exp Immunol. 2011 Nov;166(2):227-34. doi: 10.1111/j.1365-2249.2011.04437.x.
28. Modulation of signal transducers and activators of transcription (STAT) factor pathways during focal cerebral ischaemia: a gene expression array study in rat hippocampus after middle cerebral artery occlusion. Sun SL, etal., Clin Exp Pharmacol Physiol. 2007 Nov;34(11):1097-101.
29. Contrasting roles for STAT4 and STAT6 signal transduction pathways in murine renal ischemia-reperfusion injury. Yokota N, etal., Am J Physiol Renal Physiol. 2003 Aug;285(2):F319-25. Epub 2003 Apr 22.
30. STAT6 deficiency inhibits tubulointerstitial fibrosis in obstructive nephropathy. Yukawa K, etal., Int J Mol Med. 2005 Feb;15(2):225-30.
31. Imbalance of Th1 and Th2 cells in cardiac injury induced by ambient fine particles. Zhao J, etal., Toxicol Lett. 2012 Feb 5;208(3):225-31. doi: 10.1016/j.toxlet.2011.11.012. Epub 2011 Nov 23.
Additional References at PubMed
PMID:7760829   PMID:8085155   PMID:8530075   PMID:8602263   PMID:8602264   PMID:8624821   PMID:8668170   PMID:8692794   PMID:8692797   PMID:8871614   PMID:9110977   PMID:9126479  
PMID:9175833   PMID:9379007   PMID:9469446   PMID:9492006   PMID:9500796   PMID:9531287   PMID:9548487   PMID:9565645   PMID:9647237   PMID:9743537   PMID:9811885   PMID:9834104  
PMID:9846495   PMID:9881967   PMID:10051710   PMID:10200816   PMID:10227985   PMID:10227996   PMID:10349636   PMID:10400816   PMID:10438949   PMID:10452990   PMID:10490661   PMID:10508820  
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PMID:19587021   PMID:19592641   PMID:19604309   PMID:19633657   PMID:19646904   PMID:19658093   PMID:19663508   PMID:19726720   PMID:19783672   PMID:19801646   PMID:19808254   PMID:19880450  
PMID:19890042   PMID:19893030   PMID:19933870   PMID:19955520   PMID:20018622   PMID:20042469   PMID:20080304   PMID:20118929   PMID:20123960   PMID:20211142   PMID:20231466   PMID:20231889  
PMID:20304029   PMID:20304823   PMID:20418876   PMID:20483733   PMID:20498360   PMID:20581096   PMID:20584329   PMID:20605978   PMID:20624917   PMID:20625006   PMID:20691018   PMID:20699362  
PMID:20706986   PMID:20844197   PMID:20870945   PMID:20889544   PMID:20939024   PMID:20944002   PMID:20956546   PMID:20974983   PMID:21051093   PMID:21081493   PMID:21093321   PMID:21140220  
PMID:21149710   PMID:21160052   PMID:21217760   PMID:21242516   PMID:21242523   PMID:21246055   PMID:21248711   PMID:21262765   PMID:21267068   PMID:21270410   PMID:21276008   PMID:21357535  
PMID:21364747   PMID:21423619   PMID:21444669   PMID:21460847   PMID:21464207   PMID:21484783   PMID:21525389   PMID:21536806   PMID:21602491   PMID:21605467   PMID:21632710   PMID:21646476  
PMID:21690322   PMID:21731673   PMID:21751242   PMID:21765211   PMID:21826890   PMID:21873635   PMID:21911376   PMID:21931552   PMID:21945076   PMID:21949021   PMID:21949024   PMID:21959772  
PMID:21960549   PMID:21980379   PMID:22000020   PMID:22005305   PMID:22014099   PMID:22039015   PMID:22078635   PMID:22100973   PMID:22101429   PMID:22130674   PMID:22164377   PMID:22174793  
PMID:22180613   PMID:22195747   PMID:22210911   PMID:22327070   PMID:22504655   PMID:22544395   PMID:22588720   PMID:22675208   PMID:22684102   PMID:22684943   PMID:22732589   PMID:22740092  
PMID:22865229   PMID:22865552   PMID:22865856   PMID:22927819   PMID:22941735   PMID:22942430   PMID:23015710   PMID:23029313   PMID:23136202   PMID:23212947   PMID:23254356   PMID:23257358  
PMID:23257921   PMID:23275605   PMID:23288947   PMID:23303670   PMID:23351078   PMID:23383189   PMID:23392574   PMID:23420878   PMID:23435120   PMID:23504518   PMID:23509764   PMID:23536877  
PMID:23545295   PMID:23562811   PMID:23589612   PMID:23602833   PMID:23630350   PMID:23677475   PMID:23727894   PMID:23733876   PMID:23776171   PMID:23791946   PMID:23792169   PMID:23797472  
PMID:23825312   PMID:23898202   PMID:23913970   PMID:23917405   PMID:23956424   PMID:23960232   PMID:23991225   PMID:24038092   PMID:24043894   PMID:24056746   PMID:24069338   PMID:24069548  
PMID:24150243   PMID:24190658   PMID:24216482   PMID:24280725   PMID:24314139   PMID:24361497   PMID:24489947   PMID:24508458   PMID:24534206   PMID:24586307   PMID:24620029   PMID:24631157  
PMID:24634488   PMID:24646742   PMID:24647735   PMID:24695852   PMID:24717539   PMID:24751726   PMID:24777733   PMID:24792964   PMID:24828142   PMID:24845637   PMID:24906147   PMID:24906148  
PMID:25069981   PMID:25082704   PMID:25108223   PMID:25145352   PMID:25207963   PMID:25307347   PMID:25332236   PMID:25646481   PMID:25681342   PMID:25751266   PMID:25769044   PMID:25769611  
PMID:25780046   PMID:25862819   PMID:25873311   PMID:25912172   PMID:25922073   PMID:25934862   PMID:26048978   PMID:26185131   PMID:26278622   PMID:26365184   PMID:26410628   PMID:26423151  
PMID:26519105   PMID:26595887   PMID:26601901   PMID:26669445   PMID:26690703   PMID:26699812   PMID:26764350   PMID:26847546   PMID:26895644   PMID:26899911   PMID:26953325   PMID:27034374  
PMID:27080105   PMID:27216180   PMID:27273006   PMID:27336716   PMID:27417023   PMID:27417725   PMID:27510401   PMID:27554818   PMID:27568549   PMID:27581382   PMID:27605008   PMID:27626662  
PMID:27653687   PMID:27760338   PMID:27783989   PMID:27815425   PMID:27836432   PMID:27906181   PMID:28003382   PMID:28069805   PMID:28096407   PMID:28129374   PMID:28199385   PMID:28272448  
PMID:28327619   PMID:28348271   PMID:28355561   PMID:28374774   PMID:28375154   PMID:28385737   PMID:28399411   PMID:28420758   PMID:28600950   PMID:28615615   PMID:28650342   PMID:28654863  
PMID:28670633   PMID:28739140   PMID:28765368   PMID:28783681   PMID:28790455   PMID:28874416   PMID:28877454   PMID:28917204   PMID:29022575   PMID:29066614   PMID:29215829   PMID:29275858  
PMID:29304229   PMID:29343442   PMID:29436412   PMID:29513071   PMID:29518091   PMID:29587269   PMID:29590614   PMID:29593739   PMID:29674655   PMID:29688375   PMID:29728568   PMID:29738764  
PMID:29894691   PMID:29915289   PMID:29925696   PMID:30098864   PMID:30122557   PMID:30127086   PMID:30194773   PMID:30209189   PMID:30216839   PMID:30266770   PMID:30291131   PMID:30353167  
PMID:30446568   PMID:30446727   PMID:30449686   PMID:30555556   PMID:30575951   PMID:30610060   PMID:30617301   PMID:30623726   PMID:30930171   PMID:31125592   PMID:31126996   PMID:31144294  
PMID:31178059   PMID:31196774   PMID:31207335   PMID:31341159   PMID:31363052   PMID:31399281   PMID:31408278   PMID:31534167   PMID:31554795   PMID:31619589   PMID:31803941   PMID:31957000  
PMID:31961916   PMID:31974500   PMID:31980480   PMID:32247042   PMID:32298657   PMID:32397290   PMID:32471168   PMID:32554809   PMID:32757380   PMID:32814028   PMID:32863280   PMID:32870819  
PMID:32985505   PMID:33017719   PMID:33067820   PMID:33068596   PMID:33086036   PMID:33153718   PMID:33220232   PMID:33264064   PMID:33293423   PMID:33304758   PMID:33584704   PMID:33653884  
PMID:33919941   PMID:34051858   PMID:34301764   PMID:34360789   PMID:34555336   PMID:34707103   PMID:34721430   PMID:34726702   PMID:34735226   PMID:34795444   PMID:34831280   PMID:34921782  
PMID:35046382   PMID:35281012   PMID:35327639   PMID:35385697   PMID:35493520   PMID:35606692   PMID:35668064   PMID:35726645   PMID:36044899   PMID:36057627   PMID:36098746   PMID:36348405  
PMID:36426982  


Genomics

Comparative Map Data
Stat6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,478,855 - 127,496,856 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,478,855 - 127,496,826 (+)EnsemblGRCm39 Ensembl
GRCm3810127,642,955 - 127,660,987 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,642,986 - 127,660,957 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710127,080,042 - 127,098,043 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610127,046,120 - 127,063,352 (+)NCBIMGSCv36mm8
Celera10130,035,284 - 130,053,348 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.59NCBI
STAT6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,095,408 - 57,111,362 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1257,095,408 - 57,132,139 (-)EnsemblGRCh38hg38GRCh38
GRCh371257,489,191 - 57,505,145 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,775,458 - 55,791,428 (-)NCBINCBI36Build 36hg18NCBI36
Build 341255,775,461 - 55,791,428NCBI
Celera1257,143,115 - 57,159,124 (-)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,527,593 - 54,543,593 (-)NCBIHuRef
CHM1_11257,456,871 - 57,472,880 (-)NCBICHM1_1
T2T-CHM13v2.01257,063,280 - 57,079,195 (-)NCBIT2T-CHM13v2.0
Stat6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2763,480,229 - 63,497,551 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,479,642 - 63,498,495 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx765,369,479 - 65,386,799 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0767,571,769 - 67,589,089 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0767,373,031 - 67,390,379 (+)NCBIRnor_WKY
Rnor_6.0770,946,228 - 70,963,542 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,946,228 - 70,964,484 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0771,118,725 - 71,135,848 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,623,534 - 67,642,283 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1767,622,590 - 67,662,987 (+)NCBI
Celera760,619,697 - 60,637,001 (+)NCBICelera
Cytogenetic Map7q22NCBI
Stat6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554584,833,515 - 4,843,273 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554584,833,417 - 4,847,956 (-)NCBIChiLan1.0ChiLan1.0
STAT6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,232,515 - 1,247,011 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,233,691 - 1,247,075 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,297,560 - 1,307,021 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0101,243,003 - 1,257,485 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,242,995 - 1,256,854 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,220,880 - 1,230,352 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,462,887 - 1,472,341 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,587,736 - 1,597,208 (-)NCBIUU_Cfam_GSD_1.0
Stat6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,557,740 - 57,572,832 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,296,290 - 1,312,157 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049366461,297,530 - 1,312,508 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STAT6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,406,368 - 22,421,989 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,406,356 - 22,422,412 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2524,206,059 - 24,221,697 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STAT6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,005,378 - 53,020,899 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,006,145 - 53,021,203 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037192,951,160 - 192,967,461 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stat6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480210,809,252 - 10,846,693 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480210,809,234 - 10,847,762 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir135a-2mmu-miR-135a-5pOncomiRDBexternal_infoNANA22139076
Mir135a-1mmu-miR-135a-5pOncomiRDBexternal_infoNANA22139076

Predicted Target Of
Summary Value
Count of predictions:1005
Count of miRNA genes:521
Interacting mature miRNAs:633
Transcripts:ENSMUST00000092074, ENSMUST00000120279, ENSMUST00000128072, ENSMUST00000145470, ENSMUST00000156231
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
1357544Vtbt10_mvertebral trabecular bone trait 10 (mouse)Not determined1097217101130530862Mouse
4142461Bmd25_mbone mineral density 25 (mouse)Not determined1097217101130530862Mouse
11533919Mvb4_mmodifier of vibrator 4 (mouse)397217101130530862Mouse
11533921Mvb2_mmodifier of vibrator 2 (mouse)1097217101130530862Mouse
12880413V125Dq9_mvitamin D active form serum level QTL 9 (mouse)1097535905130530862Mouse
4141402T2dm1sa_mtype 2 diabetes mellitus 1 in SMXA RI mice (mouse)Not determined97758644130530862Mouse
11040593Lmr5e_mleishmaniasis resistance 5e (mouse)1099220635130530862Mouse
11040595Lmr5c_mleishmaniasis resistance 5c (mouse)1099220635130530862Mouse
11040597Lmr5a_mleishmaniasis resistance 5a (mouse)1099220635130530862Mouse
1357744Cfbw4_mcystic fibrosis body weight 4 (mouse)Not determined10100986516130530862Mouse
1301968Estq4_mestradiol regulated response QTL 4 (mouse)Not determined10100986516130530862Mouse
1301901Im5_mimmunoregulatory 5 (mouse)Not determined10101497164130530862Mouse
4141361Cfmq3_mcystic fibrosis modifier QTL 3 (mouse)Not determined10101497164130530862Mouse
1300678Leg2_mlongevity extending gene 2 (mouse)Not determined10102506908130530862Mouse
1301895Exq1_mexploratory and excitability QTL 1 (mouse)Not determined10102847852130530862Mouse
14696727Kidrq2_mkidney weight, right QTL 2 (mouse)10102902508130530862Mouse
4141007Obrq10_mobesity resistance QTL 10 (mouse)Not determined103243727130530862Mouse
4141487Tgq21_mtriglyceride QTL 21 (mouse)Not determined104110021130530862Mouse
14746996Manh69_mmandible shape 69 (mouse)10104763638130530862Mouse
1302200Sle12_msystematic lupus erythematosus susceptibility 12 (mouse)Not determined10105041304130530862Mouse
1357482Nhdlq4_mnon-HDL QTL 4 (mouse)Not determined10105041304130530862Mouse
1300679Nociq2_mnociceptive sensitivity inflammatory QTL 2 (mouse)Not determined10105041304130530862Mouse
11040594Lmr5f_mleishmaniasis resistance 5f (mouse)10105179713130530862Mouse
11040596Lmr5d_mleishmaniasis resistance 5d (mouse)10105179713130530862Mouse
11040598Lmr5b_mleishmaniasis resistance 5b (mouse)10105179713130530862Mouse
4142089Obrq9_mobesity resistance QTL 9 (mouse)Not determined108515907130530862Mouse
4141153Ltgq2_mliver triglyceride QTL 2 (mouse)Not determined108515907130530862Mouse
11041664Lmr25_mleishmaniasis resistance 25 (mouse)10108575094130530862Mouse
11039496Ltpr5b_mLeishmania tropica response 5b (mouse)10108575094130530862Mouse
11049570Lmr25b_mleishmaniasis resistance 25b (mouse)10108575094130530862Mouse
11049563Lmr25a_mleishmaniasis resistance 25a (mouse)10108575094130530862Mouse
12911218Frct3a_mfear conditioning traits 3a (mouse)10122785970129466996Mouse
12911220Frct3c_mfear conditioning traits 3c (mouse)10122785970129466996Mouse
12879490Frct3_mfear conditioning traits 3 (mouse)10122785970129466996Mouse
12904001Opfaq10_mopen field activity QTL 10 (mouse)10125633671129466375Mouse

Markers in Region
RH128335  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810127,660,991 - 127,661,171UniSTSGRCm38
MGSCv3710127,098,047 - 127,098,227UniSTSGRCm37
Celera10130,053,352 - 130,053,532UniSTS
Cytogenetic Map10D3UniSTS
cM Map1070.0UniSTS
cM Map1070.0UniSTS
AI451907  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810127,661,217 - 127,661,334UniSTSGRCm38
MGSCv3710127,098,273 - 127,098,390UniSTSGRCm37
Celera10130,053,578 - 130,053,695UniSTS
Cytogenetic Map10D3UniSTS
cM Map1070.0UniSTS
cM Map1070.0UniSTS
Whitehead/MRC_RH101381.69UniSTS
UniSTS:224451  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810127,660,120 - 127,660,282UniSTSGRCm38
MGSCv3710127,097,176 - 127,097,338UniSTSGRCm37
Celera10130,052,481 - 130,052,643UniSTS
Cytogenetic Map10D3UniSTS
cM Map1070.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC160970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF481808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF481809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC127054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM122652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U66575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000092074   ⟹   ENSMUSP00000089708
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10127,478,855 - 127,496,826 (+)Ensembl
GRCm38.p6 Ensembl10127,642,986 - 127,660,957 (+)Ensembl
RefSeq Acc Id: ENSMUST00000120279   ⟹   ENSMUSP00000112722
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10127,478,871 - 127,486,649 (+)Ensembl
GRCm38.p6 Ensembl10127,643,002 - 127,650,780 (+)Ensembl
RefSeq Acc Id: ENSMUST00000128072
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10127,488,948 - 127,490,884 (+)Ensembl
GRCm38.p6 Ensembl10127,653,079 - 127,655,015 (+)Ensembl
RefSeq Acc Id: ENSMUST00000145470
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10127,495,269 - 127,496,056 (+)Ensembl
GRCm38.p6 Ensembl10127,659,400 - 127,660,187 (+)Ensembl
RefSeq Acc Id: ENSMUST00000156231
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10127,492,630 - 127,493,797 (+)Ensembl
GRCm38.p6 Ensembl10127,656,761 - 127,657,928 (+)Ensembl
RefSeq Acc Id: NM_009284   ⟹   NP_033310
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910127,478,855 - 127,496,856 (+)NCBI
GRCm3810127,642,986 - 127,660,987 (+)NCBI
MGSCv3710127,080,042 - 127,098,043 (+)RGD
Celera10130,035,284 - 130,053,348 (+)RGD
cM Map10 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033310   ⟸   NM_009284
- UniProtKB: Q8R2F1 (UniProtKB/Swiss-Prot),   P52633 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000089708   ⟸   ENSMUST00000092074
RefSeq Acc Id: ENSMUSP00000112722   ⟸   ENSMUST00000120279
Protein Domains
SH2   STAT transcription factor protein interaction   STAT6 C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P52633-F1-model_v2 AlphaFold P52633 1-837 view protein structure

Promoters
RGD ID:6819967
Promoter ID:MM_KWN:5916
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000120279,   NM_009284
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610127,079,311 - 127,080,167 (+)MPROMDB
RGD ID:6819970
Promoter ID:MM_KWN:5917
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   ES_Cell,   Kidney,   Lung,   Spleen
Transcripts:OTTMUST00000078899
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610127,089,196 - 127,090,582 (+)MPROMDB
RGD ID:6819971
Promoter ID:MM_KWN:5918
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:OTTMUST00000078900
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610127,093,411 - 127,094,112 (+)MPROMDB
RGD ID:6819968
Promoter ID:MM_KWN:5919
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   ES_Cell,   Kidney,   Lung
Transcripts:ENSMUST00000099159
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610127,094,711 - 127,095,367 (+)MPROMDB
RGD ID:6819972
Promoter ID:MM_KWN:5920
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000078901
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610127,095,791 - 127,096,862 (+)MPROMDB
RGD ID:8673524
Promoter ID:EPDNEW_M14792
Type:initiation region
Name:Stat6_1
Description:Mus musculus signal transducer and activator of transcription6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3810127,643,024 - 127,643,084EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:103034 AgrOrtholog
Ensembl Genes ENSMUSG00000002147 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000089708 ENTREZGENE
  ENSMUSP00000089708.6 UniProtKB/Swiss-Prot
  ENSMUSP00000112722.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000092074 ENTREZGENE
  ENSMUST00000092074.12 UniProtKB/Swiss-Prot
  ENSMUST00000120279.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.532.10 UniProtKB/TrEMBL
  2.60.40.630 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT transcription factor, all-alpha domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT6_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT6_SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_TF_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_TF_coiled-coil UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_TF_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_TF_DNA-bd_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_TF_prot_interaction UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20852 UniProtKB/Swiss-Prot
MGD MGI:103034 ENTREZGENE
NCBI Gene 20852 ENTREZGENE
PANTHER PTHR11801 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT6_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_int UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Stat6 PhenoGen
PROSITE SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_int UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47655 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48092 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3YU28_MOUSE UniProtKB/TrEMBL
  P52633 ENTREZGENE
  P70383_MOUSE UniProtKB/TrEMBL
  Q3UX41_MOUSE UniProtKB/TrEMBL
  Q8R2F1 ENTREZGENE
  Q8R4D4_MOUSE UniProtKB/TrEMBL
  STAT6_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8R2F1 UniProtKB/Swiss-Prot