Scube1 (signal peptide, CUB domain, EGF-like 1) - Rat Genome Database

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Gene: Scube1 (signal peptide, CUB domain, EGF-like 1) Mus musculus
Analyze
Symbol: Scube1
Name: signal peptide, CUB domain, EGF-like 1
RGD ID: 1319122
MGI Page MGI
Description: Predicted to enable identical protein binding activity. Acts upstream of or within positive regulation of smoothened signaling pathway. Predicted to be located in external side of plasma membrane. Predicted to be active in cell surface and extracellular space. Is expressed in several structures, including allantois; embryo ectoderm; embryo mesenchyme; forelimb bud; and genitourinary system. Orthologous to human SCUBE1 (signal peptide, CUB domain and EGF like domain containing 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 7330410C13Rik; A630023E24Rik; AI604862; signal peptide, CUB and EGF-like domain-containing protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391583,486,784 - 83,609,252 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1583,489,200 - 83,609,222 (-)EnsemblGRCm39 Ensembl
GRCm381583,602,583 - 83,725,051 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1583,604,999 - 83,725,021 (-)EnsemblGRCm38mm10GRCm38
MGSCv371583,433,013 - 83,555,451 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361583,432,765 - 83,552,672 (-)NCBIMGSCv36mm8
Celera1585,729,400 - 85,852,290 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1539.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11087664   PMID:11217851   PMID:12477932   PMID:15489334   PMID:16141072   PMID:16141073   PMID:17408621   PMID:18287559  
PMID:18303018   PMID:19101956   PMID:20042401   PMID:21267068   PMID:21873635   PMID:23383134   PMID:24833801   PMID:24952961   PMID:25639508   PMID:26238476   PMID:26952977   PMID:30414502  
PMID:30722019   PMID:31040226   PMID:32325033   PMID:33308444   PMID:34321999   PMID:35225230   PMID:36005562   PMID:36971701   PMID:38355793  


Genomics

Comparative Map Data
Scube1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391583,486,784 - 83,609,252 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1583,489,200 - 83,609,222 (-)EnsemblGRCm39 Ensembl
GRCm381583,602,583 - 83,725,051 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1583,604,999 - 83,725,021 (-)EnsemblGRCm38mm10GRCm38
MGSCv371583,433,013 - 83,555,451 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361583,432,765 - 83,552,672 (-)NCBIMGSCv36mm8
Celera1585,729,400 - 85,852,290 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1539.4NCBI
SCUBE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382243,197,280 - 43,343,372 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2243,197,280 - 43,343,372 (-)EnsemblGRCh38hg38GRCh38
GRCh372243,593,286 - 43,739,378 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,929,174 - 42,069,299 (-)NCBINCBI36Build 36hg18NCBI36
Build 342241,924,495 - 42,063,785NCBI
Celera2227,509,622 - 27,649,802 (-)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2226,557,501 - 26,697,243 (-)NCBIHuRef
CHM1_12243,558,135 - 43,698,313 (-)NCBICHM1_1
T2T-CHM13v2.02243,678,148 - 43,824,408 (-)NCBIT2T-CHM13v2.0
Scube1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87116,639,027 - 116,760,986 (-)NCBIGRCr8
mRatBN7.27114,759,016 - 114,880,995 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7114,759,010 - 114,880,940 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7116,509,203 - 116,628,031 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07118,734,817 - 118,853,590 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07118,704,287 - 118,823,059 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07124,501,988 - 124,620,755 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7124,501,988 - 124,620,703 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07124,489,541 - 124,608,699 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47121,631,922 - 121,750,650 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17121,666,488 - 121,784,905 (-)NCBI
Celera7111,073,455 - 111,191,327 (-)NCBICelera
Cytogenetic Map7q34NCBI
Scube1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541328,338,254 - 28,461,626 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541328,339,212 - 28,461,626 (-)NCBIChiLan1.0ChiLan1.0
SCUBE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22353,020,555 - 53,167,389 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12255,710,830 - 55,860,239 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02224,080,438 - 24,228,401 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12242,284,599 - 42,420,662 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2242,285,374 - 42,420,761 (-)Ensemblpanpan1.1panPan2
SCUBE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11022,164,430 - 22,358,981 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1022,222,208 - 22,353,729 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1022,155,509 - 22,295,664 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01022,963,388 - 23,103,461 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1022,963,226 - 23,097,926 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11022,682,666 - 22,822,811 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01023,001,794 - 23,136,929 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01023,177,382 - 23,317,612 (+)NCBIUU_Cfam_GSD_1.0
Scube1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049455,831,359 - 5,958,038 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367181,027,368 - 1,150,465 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367181,026,770 - 1,150,465 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCUBE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl55,561,505 - 5,692,328 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.155,561,479 - 5,692,339 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.253,050,715 - 3,114,980 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SCUBE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11925,731,128 - 25,873,120 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604599,563,297 - 99,708,929 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scube1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247525,673,332 - 5,780,634 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247525,673,335 - 5,783,615 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Scube1
4527 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4453
Count of miRNA genes:822
Interacting mature miRNAs:1087
Transcripts:ENSMUST00000016907, ENSMUST00000043634, ENSMUST00000076060, ENSMUST00000144773, ENSMUST00000171496
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
11532732Pitm5_mprion incubation time 5 (mouse)158296406187054388Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1301472Pain1_mpain 1 (mouse)Not determined157532084690813185Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82615474104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse

Markers in Region
Scube1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381583,605,045 - 83,605,462UniSTSGRCm38
MGSCv371583,435,475 - 83,435,892UniSTSGRCm37
Celera1585,731,862 - 85,732,279UniSTS
Cytogenetic Map15E1UniSTS
cM Map15 UniSTS
AI604862  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381583,602,634 - 83,602,771UniSTSGRCm38
MGSCv371583,433,064 - 83,433,201UniSTSGRCm37
Celera1585,729,451 - 85,729,588UniSTS
Cytogenetic Map15E1UniSTS
Whitehead/MRC_RH15730.29UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001271472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_022723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF276425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL583887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL591964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC080278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ104466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000016907   ⟹   ENSMUSP00000016907
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1583,490,707 - 83,609,222 (-)Ensembl
GRCm38.p6 Ensembl1583,606,506 - 83,725,021 (-)Ensembl
Ensembl Acc Id: ENSMUST00000043634   ⟹   ENSMUSP00000044835
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1583,489,204 - 83,609,222 (-)Ensembl
GRCm38.p6 Ensembl1583,605,003 - 83,725,021 (-)Ensembl
Ensembl Acc Id: ENSMUST00000076060   ⟹   ENSMUSP00000075434
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1583,490,707 - 83,609,222 (-)Ensembl
GRCm38.p6 Ensembl1583,606,506 - 83,725,021 (-)Ensembl
Ensembl Acc Id: ENSMUST00000144773
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1583,489,200 - 83,609,222 (-)Ensembl
GRCm38.p6 Ensembl1583,604,999 - 83,725,021 (-)Ensembl
Ensembl Acc Id: ENSMUST00000171496   ⟹   ENSMUSP00000130131
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1583,491,524 - 83,609,127 (-)Ensembl
GRCm38.p6 Ensembl1583,607,323 - 83,724,926 (-)Ensembl
Ensembl Acc Id: ENSMUST00000229057
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1583,540,791 - 83,544,681 (-)Ensembl
GRCm38.p6 Ensembl1583,656,590 - 83,660,480 (-)Ensembl
Ensembl Acc Id: ENSMUST00000230060
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1583,490,832 - 83,497,940 (-)Ensembl
GRCm38.p6 Ensembl1583,606,631 - 83,613,739 (-)Ensembl
RefSeq Acc Id: NM_001271472   ⟹   NP_001258401
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391583,486,784 - 83,609,240 (-)NCBI
GRCm381583,602,583 - 83,725,039 (-)NCBI
Celera1585,729,400 - 85,852,308 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001271473   ⟹   NP_001258402
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391583,486,784 - 83,609,240 (-)NCBI
GRCm381583,602,583 - 83,725,039 (-)NCBI
Celera1585,729,400 - 85,852,308 (-)NCBI
Sequence:
RefSeq Acc Id: NM_022723   ⟹   NP_073560
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391583,486,784 - 83,609,240 (-)NCBI
GRCm381583,602,583 - 83,725,039 (-)NCBI
MGSCv371583,433,013 - 83,555,451 (-)RGD
Celera1585,729,400 - 85,852,308 (-)NCBI
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006521242   ⟹   XP_006521305
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391583,486,784 - 83,609,248 (-)NCBI
GRCm381583,602,583 - 83,725,048 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017316719   ⟹   XP_017172208
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391583,492,526 - 83,609,249 (-)NCBI
GRCm381583,608,325 - 83,725,048 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036159534   ⟹   XP_036015427
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391583,502,803 - 83,609,252 (-)NCBI
Sequence:
RefSeq Acc Id: NP_073560   ⟸   NM_022723
- Peptide Label: isoform b precursor
- UniProtKB: A2A442 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258402   ⟸   NM_001271473
- Peptide Label: isoform c precursor
- UniProtKB: Q68EF9 (UniProtKB/TrEMBL),   A2A442 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258401   ⟸   NM_001271472
- Peptide Label: isoform a precursor
- UniProtKB: Q8C9Q4 (UniProtKB/Swiss-Prot),   Q9EQC6 (UniProtKB/Swiss-Prot),   Q6NZL8 (UniProtKB/Swiss-Prot),   A2A442 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006521305   ⟸   XM_006521242
- Peptide Label: isoform X2
- UniProtKB: A2A442 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017172208   ⟸   XM_017316719
- Peptide Label: isoform X1
- UniProtKB: A2A442 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000130131   ⟸   ENSMUST00000171496
Ensembl Acc Id: ENSMUSP00000075434   ⟸   ENSMUST00000076060
Ensembl Acc Id: ENSMUSP00000016907   ⟸   ENSMUST00000016907
Ensembl Acc Id: ENSMUSP00000044835   ⟸   ENSMUST00000043634
RefSeq Acc Id: XP_036015427   ⟸   XM_036159534
- Peptide Label: isoform X3
Protein Domains
CUB   EGF-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6NZL8-F1-model_v2 AlphaFold Q6NZL8 1-1018 view protein structure

Promoters
RGD ID:6826456
Promoter ID:MM_KWN:19260
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000016907,   ENSMUST00000043634,   ENSMUST00000076060,   NM_022723,   OTTMUST00000049853
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361583,555,256 - 83,555,756 (-)MPROMDB
RGD ID:8684582
Promoter ID:EPDNEW_M20321
Type:initiation region
Name:Scube1_1
Description:Mus musculus signal peptide, CUB domain, EGF-like 1 , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381583,725,013 - 83,725,073EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1890616 AgrOrtholog
Ensembl Genes ENSMUSG00000016763 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000016907 ENTREZGENE
  ENSMUST00000016907.8 UniProtKB/Swiss-Prot
  ENSMUST00000043634 ENTREZGENE
  ENSMUST00000043634.12 UniProtKB/TrEMBL
  ENSMUST00000076060.12 UniProtKB/TrEMBL
  ENSMUST00000171496 ENTREZGENE
  ENSMUST00000171496.9 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.290 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tumor Necrosis Factor Receptor, subunit A, domain 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro cEGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CUB_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NOTCH1_EGF-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SCUB_EGF-like_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sperma_CUB_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr-kin_ephrin_A/B_rcpt-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:64706 UniProtKB/Swiss-Prot
MGD MGI:1890616 ENTREZGENE
NCBI Gene 64706 ENTREZGENE
PANTHER SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam cEGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CUB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ephrin_rec_like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FXa_inhibition UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Scube1 PhenoGen
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CUB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CUB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ephrin_rec_like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49854 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57184 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2A442 ENTREZGENE, UniProtKB/TrEMBL
  Q68EF9 ENTREZGENE, UniProtKB/TrEMBL
  Q6NZL8 ENTREZGENE
  Q8C9Q4 ENTREZGENE
  Q9EQC6 ENTREZGENE
  SCUB1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8C9Q4 UniProtKB/Swiss-Prot
  Q9EQC6 UniProtKB/Swiss-Prot