Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | H13 | Mouse | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of H13 mRNA] | CTD | PMID:22206623 | H13 | Mouse | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of H13 mRNA | CTD | PMID:22206623 | H13 | Mouse | 17beta-estradiol | decreases expression | ISO | HM13 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of HM13 mRNA | CTD | PMID:16705744 | H13 | Mouse | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of HM13 mRNA | CTD | PMID:29581250 | H13 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of H13 mRNA | CTD | PMID:19933214 | H13 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of H13 mRNA | CTD | PMID:21570461 | H13 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of H13 mRNA and Tetrachlorodibenzodioxin results in increased expression of HM13 mRNA | CTD | PMID:18796159 more ... | H13 | Mouse | 3,4-methylenedioxymethamphetamine | decreases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of H13 mRNA | CTD | PMID:26251327 | H13 | Mouse | 3,4-methylenedioxymethamphetamine | increases methylation | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased methylation of H13 promoter | CTD | PMID:26251327 | H13 | Mouse | 3-chloropropane-1,2-diol | increases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in increased expression of HM13 protein | CTD | PMID:34915118 | H13 | Mouse | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of HM13 mRNA | CTD | PMID:28628672 | H13 | Mouse | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of H13 mRNA | CTD | PMID:18648102 | H13 | Mouse | 4,4'-sulfonyldiphenol | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of HM13 mRNA | CTD | PMID:28628672 | H13 | Mouse | 5-fluorouracil | affects expression | ISO | HM13 (Homo sapiens) | 6480464 | Fluorouracil affects the expression of HM13 mRNA | CTD | PMID:16584549 | H13 | Mouse | acrylamide | increases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of HM13 mRNA | CTD | PMID:28959563 | H13 | Mouse | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of H13 mRNA | CTD | PMID:19770486 | H13 | Mouse | aflatoxin B1 | increases methylation | ISO | HM13 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of HM13 intron | CTD | PMID:30157460 | H13 | Mouse | arsenous acid | decreases expression | ISO | HM13 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of HM13 protein | CTD | PMID:25419056 | H13 | Mouse | atrazine | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Atrazine results in increased expression of HM13 mRNA | CTD | PMID:22378314 | H13 | Mouse | benzo[a]pyrene | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of HM13 mRNA | CTD | PMID:26238291 | H13 | Mouse | benzo[a]pyrene | decreases methylation | ISO | HM13 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of HM13 3' UTR and Benzo(a)pyrene results in decreased methylation of HM13 promoter | CTD | PMID:27901495 | H13 | Mouse | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of H13 mRNA | CTD | PMID:27858113 | H13 | Mouse | benzo[b]fluoranthene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of H13 mRNA | CTD | PMID:27858113 | H13 | Mouse | benzo[e]pyrene | decreases methylation | ISO | HM13 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of HM13 intron | CTD | PMID:30157460 | H13 | Mouse | bisphenol A | increases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of HM13 mRNA | CTD | PMID:25181051 | H13 | Mouse | bisphenol A | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of HM13 protein | CTD | PMID:34186270 | H13 | Mouse | bisphenol A | decreases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of HM13 mRNA | CTD | PMID:30816183 and PMID:34947998 | H13 | Mouse | bisphenol A | affects expression | ISO | HM13 (Homo sapiens) | 6480464 | bisphenol A affects the expression of HM13 mRNA | CTD | PMID:30903817 | H13 | Mouse | Bisphenol B | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of HM13 protein | CTD | PMID:34186270 | H13 | Mouse | bisphenol F | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of HM13 protein | CTD | PMID:34186270 | H13 | Mouse | cadmium dichloride | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of HM13 mRNA | CTD | PMID:26472689 and PMID:38568856 | H13 | Mouse | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | H13 | Mouse | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of H13 mRNA | CTD | PMID:37019170 | H13 | Mouse | chrysene | decreases expression | EXP | | 6480464 | chrysene results in decreased expression of H13 mRNA | CTD | PMID:26377693 | H13 | Mouse | chrysene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of H13 mRNA | CTD | PMID:27858113 | H13 | Mouse | clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of H13 mRNA | CTD | PMID:17585979 | H13 | Mouse | clofibric acid | multiple interactions | ISO | Hm13 (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of H13 mRNA | CTD | PMID:17602206 | H13 | Mouse | cobalt dichloride | decreases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | cobaltous chloride results in decreased expression of HM13 mRNA | CTD | PMID:24386269 | H13 | Mouse | cyclophosphamide | decreases expression | EXP | | 6480464 | Cyclophosphamide results in decreased expression of H13 mRNA | CTD | PMID:15331540 | H13 | Mouse | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of H13 mRNA | CTD | PMID:19770486 | H13 | Mouse | cyclosporin A | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of HM13 mRNA | CTD | PMID:20106945 more ... | H13 | Mouse | decabromodiphenyl ether | affects expression | ISO | HM13 (Homo sapiens) | 6480464 | decabromobiphenyl ether affects the expression of HM13 mRNA | CTD | PMID:24834073 | H13 | Mouse | dexamethasone | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of HM13 mRNA | CTD | PMID:28628672 | H13 | Mouse | diarsenic trioxide | decreases expression | ISO | HM13 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of HM13 protein | CTD | PMID:25419056 | H13 | Mouse | diethylstilbestrol | decreases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | Diethylstilbestrol results in decreased expression of HM13 mRNA | CTD | PMID:36653537 | H13 | Mouse | diuron | decreases expression | ISO | HM13 (Homo sapiens) | 6480464 | Diuron results in decreased expression of HM13 mRNA | CTD | PMID:35967413 | H13 | Mouse | endosulfan | increases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of HM13 mRNA | CTD | PMID:29391264 | H13 | Mouse | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of H13 mRNA | CTD | PMID:35436446 | H13 | Mouse | fenthion | increases expression | EXP | | 6480464 | Fenthion results in increased expression of H13 mRNA | CTD | PMID:34813904 | H13 | Mouse | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of H13 mRNA | CTD | PMID:25629700 | H13 | Mouse | folic acid | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of H13 mRNA] | CTD | PMID:22206623 | H13 | Mouse | FR900359 | increases phosphorylation | ISO | HM13 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of HM13 protein | CTD | PMID:37730182 | H13 | Mouse | genistein | decreases expression | ISO | HM13 (Homo sapiens) | 6480464 | Genistein results in decreased expression of HM13 mRNA | CTD | PMID:16705744 | H13 | Mouse | glafenine | increases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | Glafenine results in increased expression of HM13 mRNA | CTD | PMID:24136188 | H13 | Mouse | glyphosate | affects methylation | ISO | HM13 (Homo sapiens) | 6480464 | Glyphosate affects the methylation of HM13 gene | CTD | PMID:35377194 | H13 | Mouse | indometacin | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of HM13 mRNA | CTD | PMID:28628672 | H13 | Mouse | ivermectin | decreases expression | ISO | HM13 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of HM13 protein | CTD | PMID:32959892 | H13 | Mouse | leflunomide | increases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | leflunomide results in increased expression of HM13 mRNA | CTD | PMID:24136188 | H13 | Mouse | methapyrilene | decreases methylation | ISO | HM13 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of HM13 intron | CTD | PMID:30157460 | H13 | Mouse | methidathion | increases expression | EXP | | 6480464 | methidathion results in increased expression of H13 mRNA | CTD | PMID:34813904 | H13 | Mouse | N-nitrosodiethylamine | multiple interactions | ISO | Hm13 (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of H13 mRNA | CTD | PMID:17602206 | H13 | Mouse | nickel atom | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Nickel results in increased expression of HM13 mRNA | CTD | PMID:24768652 | H13 | Mouse | ozone | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of HM13 mRNA | CTD | PMID:35430440 | H13 | Mouse | paracetamol | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of HM13 mRNA | CTD | PMID:29067470 | H13 | Mouse | paracetamol | decreases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of HM13 mRNA | CTD | PMID:33387578 | H13 | Mouse | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of H13 mRNA | CTD | PMID:21371552 | H13 | Mouse | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of H13 mRNA | CTD | PMID:23091169 | H13 | Mouse | pirinixic acid | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of HM13 mRNA | CTD | PMID:19710929 | H13 | Mouse | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of H13 mRNA | CTD | PMID:23811191 | H13 | Mouse | resveratrol | increases expression | EXP | | 6480464 | resveratrol results in increased expression of H13 protein | CTD | PMID:25505154 | H13 | Mouse | SB 431542 | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of HM13 protein | CTD | PMID:37664457 | H13 | Mouse | silicon dioxide | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of HM13 mRNA | CTD | PMID:25895662 | H13 | Mouse | silver atom | decreases expression | EXP | | 6480464 | Silver results in decreased expression of H13 mRNA | CTD | PMID:27131904 | H13 | Mouse | silver(0) | decreases expression | EXP | | 6480464 | Silver results in decreased expression of H13 mRNA | CTD | PMID:27131904 | H13 | Mouse | sodium arsenite | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of HM13 mRNA | CTD | PMID:38568856 | H13 | Mouse | Soman | increases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | Soman results in increased expression of H13 mRNA | CTD | PMID:19281266 | H13 | Mouse | sulindac sulfide | affects binding | ISO | HM13 (Homo sapiens) | 6480464 | sulindac sulfide binds to HM13 protein | CTD | PMID:17932033 | H13 | Mouse | sulindac sulfide | multiple interactions | ISO | HM13 (Homo sapiens) | 6480464 | sulindac sulfide inhibits the reaction [L 685458 binds to HM13 protein] | CTD | PMID:17932033 | H13 | Mouse | testosterone | multiple interactions | EXP | | 6480464 | 1 more ... | CTD | PMID:33848595 | H13 | Mouse | testosterone | decreases expression | EXP | | 6480464 | Testosterone deficiency results in decreased expression of H13 mRNA | CTD | PMID:33848595 | H13 | Mouse | tetraphene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of H13 mRNA | CTD | PMID:27858113 | H13 | Mouse | thapsigargin | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of HM13 mRNA | CTD | PMID:22378314 | H13 | Mouse | theophylline | affects binding | ISO | HM13 (Homo sapiens) | 6480464 | Theophylline binds to HM13 protein | CTD | PMID:18951874 | H13 | Mouse | thioacetamide | decreases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of HM13 mRNA | CTD | PMID:23411599 | H13 | Mouse | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of H13 mRNA | CTD | PMID:27760801 | H13 | Mouse | trichloroethene | increases expression | ISO | Hm13 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of HM13 mRNA | CTD | PMID:33387578 | H13 | Mouse | triphenyl phosphate | affects expression | ISO | HM13 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of HM13 mRNA | CTD | PMID:37042841 | H13 | Mouse | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of H13 mRNA | CTD | PMID:33045310 | H13 | Mouse | tunicamycin | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of HM13 mRNA | CTD | PMID:22378314 | H13 | Mouse | valproic acid | increases expression | ISO | HM13 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of HM13 mRNA | CTD | PMID:23179753 | H13 | Mouse | valproic acid | affects expression | ISO | HM13 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of HM13 mRNA | CTD | PMID:25979313 | |