Psph (phosphoserine phosphatase) - Rat Genome Database

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Gene: Psph (phosphoserine phosphatase) Mus musculus
Analyze
Symbol: Psph
Name: phosphoserine phosphatase
RGD ID: 1318727
MGI Page MGI
Description: Predicted to enable L-phosphoserine phosphatase activity; magnesium ion binding activity; and protein homodimerization activity. Acts upstream of or within in utero embryonic development. Predicted to be located in neuron projection. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; integumental system; liver; and urinary system. Human ortholog(s) of this gene implicated in PSPH deficiency. Orthologous to human PSPH (phosphoserine phosphatase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI480570; O-phosphoserine phosphohydrolase; P; PSP; PSPase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395129,842,622 - 129,864,318 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5129,842,622 - 129,864,513 (-)EnsemblGRCm39 Ensembl
GRCm385129,765,558 - 129,787,443 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5129,765,558 - 129,787,449 (-)EnsemblGRCm38mm10GRCm38
MGSCv375130,271,434 - 130,293,129 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365130,080,273 - 130,101,913 (-)NCBIMGSCv36mm8
Celera5126,809,895 - 126,831,826 (-)NCBICelera
Cytogenetic Map5G1.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,10-phenanthroline  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3-chloropropane-1,2-diol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
antimony(0)  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
clobetasol  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumarin 460  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
dorsomorphin  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (EXP)
folpet  (EXP)
formaldehyde  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
menadione  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-nitrosodiethylamine  (EXP)
neomycin  (EXP)
nickel dichloride  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenylephrine  (ISO)
phorone  (ISO)
pirinixic acid  (EXP)
quercetin  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
Tributyltin oxide  (EXP)
trichloroethene  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
trovafloxacin  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adenohypophysis morphology  (IEA)
abnormal bile duct morphology  (IEA)
abnormal brain commissure morphology  (IEA)
abnormal brain internal capsule morphology  (IEA)
abnormal choroid plexus morphology  (IEA)
abnormal craniofacial morphology  (IEA)
abnormal dorsal root ganglion topology  (IEA)
abnormal ductus venosus valve topology  (IEA)
abnormal duodenum topology  (IEA)
abnormal embryo size  (IEA)
abnormal external auditory canal morphology  (IEA)
abnormal eye morphology  (IEA)
abnormal eye muscle morphology  (IEA)
abnormal facial nerve topology  (IEA)
abnormal femur morphology  (IEA)
abnormal forebrain morphology  (IEA)
abnormal heart morphology  (IEA)
abnormal hindbrain morphology  (IEA)
abnormal hypoglossal nerve topology  (IEA)
abnormal inferior vena cava morphology  (IEA)
abnormal infrahyoid muscle connection  (IEA)
abnormal interatrial septum morphology  (IEA)
abnormal larynx morphology  (IEA)
abnormal lens morphology  (IEA)
abnormal midbrain morphology  (IEA)
abnormal middle ear ossicle morphology  (IEA)
abnormal nasal cavity morphology  (IEA)
abnormal nasal septum morphology  (IEA)
abnormal neurohypophysis morphology  (IEA)
abnormal olfactory bulb morphology  (IEA)
abnormal olfactory nerve morphology  (IEA)
abnormal optic cup morphology  (IEA)
abnormal optic stalk morphology  (IEA)
abnormal oral cavity morphology  (IEA)
abnormal outer ear morphology  (IEA)
abnormal parasellar internal carotid artery branch morphology  (IEA)
abnormal pelvic girdle bone morphology  (IEA)
abnormal pineal gland morphology  (IEA)
abnormal placenta morphology  (IAGP)
abnormal placental labyrinth vasculature morphology  (IAGP)
abnormal posterior semicircular canal morphology  (IEA)
abnormal pulmonary artery origin  (IEA)
abnormal salivary gland morphology  (IEA)
abnormal semicircular canal morphology  (IEA)
abnormal sphenoid bone morphology  (IEA)
abnormal spinal cord central canal morphology  (IEA)
abnormal thymus morphology  (IEA)
abnormal thymus topology  (IEA)
abnormal thyroid gland morphology  (IEA)
abnormal trophoblast layer morphology  (IAGP)
abnormal vertebral artery origin  (IEA)
abnormal vertebral body morphology  (IEA)
abnormal vitelline vein connection  (IEA)
abnormal vomeronasal organ morphology  (IEA)
abnormal Wolffian duct morphology  (IEA)
absent abducens nerve  (IEA)
absent brain internal capsule  (IEA)
absent celiac artery  (IEA)
absent connection between subcutaneous lymph vessels and lymph sac  (IEA)
absent external auditory canal  (IEA)
absent eye muscles  (IEA)
absent hypoglossal nerve  (IEA)
absent maxilla  (IEA)
absent neurohypophysis  (IEA)
absent olfactory bulb  (IEA)
absent olfactory nerve  (IEA)
absent optic chiasm  (IEA)
absent pineal gland  (IEA)
absent portal vein segment  (IEA)
absent posterior commissure  (IEA)
absent salivary gland  (IEA)
absent segment of posterior cerebral artery  (IEA)
absent stapedial artery  (IEA)
absent tongue  (IEA)
absent trochlear nerve  (IEA)
absent vomeronasal organ  (IEA)
anastomosis between middle cerebral arteries  (IEA)
anophthalmia  (IEA)
aorta coarctation  (IEA)
aphakia  (IEA)
athymia  (IEA)
basal brain tissue herniation  (IEA)
blood in lymph vessels  (IEA)
cardiovascular system phenotype  (IEA)
decreased circulating triglyceride level  (IEA)
double outlet right ventricle  (IEA)
edema  (IEA)
embryo cyst  (IEA)
embryonic growth retardation  (IAGP)
epithelioid cyst  (IEA)
fetal growth retardation  (IEA)
fragmented Meckel's cartilage  (IEA)
fusion of vertebral arches  (IEA)
fusion of vertebral bodies  (IEA)
herniated liver  (IEA)
heterochrony  (IEA)
holoprosencephaly  (IEA)
increased heart rate variability  (IEA)
increased rib number  (IEA)
increased trigeminal neuroma incidence  (IEA)
intestinal/bowel diverticulum  (IEA)
intraembryonal intestine elongation  (IEA)
microphthalmia  (IEA)
muscular ventricular septal defect  (IEA)
oligodactyly  (IEA)
pale placenta  (IEA)
pale yolk sac  (IEA)
pallor  (IEA)
perimembraneous ventricular septal defect  (IEA)
persistent trigeminal artery  (IEA)
persistent truncus arteriosis  (IEA)
placenta hemorrhage  (IAGP)
placenta necrosis  (IAGP)
preweaning lethality, complete penetrance  (IAGP)
rib fusion  (IEA)
short Meckel's cartilage  (IEA)
small adrenal glands  (IEA)
small kidney  (IEA)
small placenta  (IAGP)
small salivary gland  (IEA)
small superior cervical ganglion  (IEA)
spleen hypoplasia  (IEA)
subcutaneous edema  (IAGP)
thin cerebral cortex  (IEA)
thoracoschisis  (IEA)
thrombocytopenia  (IEA)
tongue hypoplasia  (IEA)
umbilical vein stenosis  (IEA)
References

References - curated
# Reference Title Reference Citation
1. The effects of hyperphenylalaninemia on fetal development: a new animal model of maternal phenylketonuria. Brass CA, etal., Pediatr Res. 1982 May;16(5):388-94.
2. Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations. Easterday MC, etal., Dev Biol 2003 Dec 15;264(2):309-22.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:6690234   PMID:8563168   PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11239426   PMID:12477932   PMID:14610273   PMID:14681479  
PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:17495110   PMID:18228065   PMID:18799693   PMID:21267068   PMID:21726982   PMID:21873635   PMID:24194600   PMID:24457600  
PMID:27626380   PMID:27996060   PMID:28185240   PMID:28650483   PMID:29539633   PMID:30550785   PMID:31077711   PMID:35237793   PMID:36639869   PMID:36737727  


Genomics

Comparative Map Data
Psph
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395129,842,622 - 129,864,318 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5129,842,622 - 129,864,513 (-)EnsemblGRCm39 Ensembl
GRCm385129,765,558 - 129,787,443 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5129,765,558 - 129,787,449 (-)EnsemblGRCm38mm10GRCm38
MGSCv375130,271,434 - 130,293,129 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365130,080,273 - 130,101,913 (-)NCBIMGSCv36mm8
Celera5126,809,895 - 126,831,826 (-)NCBICelera
Cytogenetic Map5G1.3NCBI
PSPH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38756,011,064 - 56,051,444 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl756,011,051 - 56,051,604 (-)EnsemblGRCh38hg38GRCh38
GRCh37756,078,757 - 56,119,137 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36756,046,238 - 56,086,762 (-)NCBINCBI36Build 36hg18NCBI36
Build 34755,852,953 - 55,893,477NCBI
Celera767,132,178 - 67,172,669 (-)NCBICelera
Cytogenetic Map7p11.2NCBI
HuRef755,892,706 - 55,933,068 (-)NCBIHuRef
CHM1_1756,081,776 - 56,122,305 (-)NCBICHM1_1
T2T-CHM13v2.0756,170,861 - 56,211,278 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2756,082,991 - 56,123,515 (-)NCBI
Psph
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21226,882,524 - 26,905,084 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1226,883,133 - 26,905,074 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1228,027,799 - 28,041,053 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01228,638,338 - 28,651,592 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01227,699,824 - 27,713,078 (+)NCBIRnor_WKY
Rnor_6.01230,514,128 - 30,526,551 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1230,514,112 - 30,526,557 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,455,767 - 32,468,319 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41227,969,748 - 27,984,318 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11227,833,136 - 27,847,706 (-)NCBI
Celera1228,596,700 - 28,610,791 (+)NCBICelera
Cytogenetic Map12q13NCBI
Psph
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554568,198,739 - 8,212,025 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554568,198,739 - 8,212,111 (-)NCBIChiLan1.0ChiLan1.0
LOC100993185
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan17108,915,322 - 108,940,625 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0756,351,434 - 56,376,714 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1756,772,872 - 56,799,703 (+)NCBIpanpan1.1PanPan1.1panPan2
PSPH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.16493,152 - 546,176 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl6493,176 - 512,089 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha62,192,384 - 2,245,452 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.06296,475 - 349,789 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl6295,715 - 349,758 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.16240,702 - 293,550 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.06234,329 - 287,631 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.06405,548 - 458,858 (-)NCBIUU_Cfam_GSD_1.0
Psph
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344126,114,035 - 126,136,253 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365437,900,283 - 7,922,541 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365437,900,319 - 7,922,529 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSPH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl316,877,923 - 16,907,952 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1316,877,904 - 16,903,062 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2317,136,056 - 17,161,335 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PSPH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1212,728,490 - 2,761,805 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl212,753,284 - 2,757,008 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041179,930,973 - 179,974,113 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psph
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247408,213,574 - 8,226,224 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247408,212,051 - 8,233,358 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Psph
977 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:503
Count of miRNA genes:334
Interacting mature miRNAs:366
Transcripts:ENSMUST00000031399, ENSMUST00000118268, ENSMUST00000136280, ENSMUST00000136507, ENSMUST00000178244
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596320385130320533Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined597021753131021986Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined597021753131021986Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100665965134665965Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100665965134665965Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101332579135332579Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101863832135864028Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115156883149157015Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115156883149157015Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118948964151758149Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119945037141700466Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119945037149347326Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121455402151758149Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121555236151758149Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124700335151758149Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125133457151758149Mouse
1301715Elmaz2_melevated maze behavior 2 (mouse)Not determined5125178229141700466Mouse
13464142Bbaa2a_mB.burgdorferi-associated arthritis 2a (mouse)5128571199130052971Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129520084151758149Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129787831151758149Mouse

Markers in Region
AI480570  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385129,765,789 - 129,765,870UniSTSGRCm38
MGSCv375130,271,665 - 130,271,746UniSTSGRCm37
Celera5126,810,126 - 126,810,207UniSTS
Cytogenetic Map5G1.3UniSTS
Whitehead/MRC_RH51567.54UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_133900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006504274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006504275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017320574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA003039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC120413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC186296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI841354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ177662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY125431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY127546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV560928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG954262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000031399   ⟹   ENSMUSP00000031399
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5129,842,622 - 129,864,513 (-)Ensembl
GRCm38.p6 Ensembl5129,765,558 - 129,787,449 (-)Ensembl
RefSeq Acc Id: ENSMUST00000118268   ⟹   ENSMUSP00000113671
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5129,842,622 - 129,856,237 (-)Ensembl
GRCm38.p6 Ensembl5129,765,558 - 129,779,173 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136280
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5129,846,307 - 129,848,219 (-)Ensembl
GRCm38.p6 Ensembl5129,769,243 - 129,771,155 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136507   ⟹   ENSMUSP00000116292
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5129,847,764 - 129,864,218 (-)Ensembl
GRCm38.p6 Ensembl5129,770,700 - 129,787,154 (-)Ensembl
RefSeq Acc Id: ENSMUST00000178244
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5129,853,930 - 129,864,316 (-)Ensembl
GRCm38.p6 Ensembl5129,776,866 - 129,787,252 (-)Ensembl
RefSeq Acc Id: ENSMUST00000201022
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5129,848,484 - 129,856,270 (-)Ensembl
GRCm38.p6 Ensembl5129,771,420 - 129,779,206 (-)Ensembl
RefSeq Acc Id: ENSMUST00000201394   ⟹   ENSMUSP00000144667
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5129,846,383 - 129,856,277 (-)Ensembl
GRCm38.p6 Ensembl5129,769,319 - 129,779,213 (-)Ensembl
RefSeq Acc Id: ENSMUST00000202374
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5129,856,445 - 129,864,271 (-)Ensembl
GRCm38.p6 Ensembl5129,779,381 - 129,787,207 (-)Ensembl
RefSeq Acc Id: NM_133900   ⟹   NP_598661
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395129,842,622 - 129,864,317 (-)NCBI
GRCm385129,765,558 - 129,787,253 (-)ENTREZGENE
MGSCv375130,271,434 - 130,293,129 (-)RGD
Celera5126,809,895 - 126,831,826 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006504274   ⟹   XP_006504337
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395129,842,622 - 129,864,318 (-)NCBI
GRCm385129,765,558 - 129,787,443 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006504275   ⟹   XP_006504338
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395129,842,622 - 129,848,214 (-)NCBI
GRCm385129,765,558 - 129,771,153 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017320574   ⟹   XP_017176063
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395129,842,622 - 129,855,650 (-)NCBI
GRCm385129,765,558 - 129,778,586 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254011   ⟹   XP_030109871
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395129,842,622 - 129,864,286 (-)NCBI
GRCm385129,765,558 - 129,787,222 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254012   ⟹   XP_030109872
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395129,842,622 - 129,864,008 (-)NCBI
GRCm385129,765,558 - 129,786,931 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254013   ⟹   XP_030109873
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395129,842,622 - 129,864,008 (-)NCBI
GRCm385129,765,558 - 129,786,919 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164689   ⟹   XP_036020582
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395129,842,622 - 129,864,108 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_598661   ⟸   NM_133900
- UniProtKB: Q5XHW3 (UniProtKB/Swiss-Prot),   Q99LS3 (UniProtKB/Swiss-Prot),   A0A6P7R7S5 (UniProtKB/TrEMBL),   A0A8C6GER1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006504337   ⟸   XM_006504274
- Peptide Label: isoform X1
- UniProtKB: Q5XHW3 (UniProtKB/Swiss-Prot),   Q99LS3 (UniProtKB/Swiss-Prot),   A0A6P7R7S5 (UniProtKB/TrEMBL),   A0A8C6GER1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006504338   ⟸   XM_006504275
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017176063   ⟸   XM_017320574
- Peptide Label: isoform X1
- UniProtKB: Q5XHW3 (UniProtKB/Swiss-Prot),   Q99LS3 (UniProtKB/Swiss-Prot),   A0A6P7R7S5 (UniProtKB/TrEMBL),   A0A8C6GER1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030109871   ⟸   XM_030254011
- Peptide Label: isoform X1
- UniProtKB: Q5XHW3 (UniProtKB/Swiss-Prot),   A0A6P7R7S5 (UniProtKB/TrEMBL),   A0A8C6GER1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030109872   ⟸   XM_030254012
- Peptide Label: isoform X1
- UniProtKB: Q5XHW3 (UniProtKB/Swiss-Prot),   A0A6P7R7S5 (UniProtKB/TrEMBL),   A0A8C6GER1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030109873   ⟸   XM_030254013
- Peptide Label: isoform X1
- UniProtKB: Q5XHW3 (UniProtKB/Swiss-Prot),   A0A6P7R7S5 (UniProtKB/TrEMBL),   A0A8C6GER1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000113671   ⟸   ENSMUST00000118268
RefSeq Acc Id: ENSMUSP00000031399   ⟸   ENSMUST00000031399
RefSeq Acc Id: ENSMUSP00000144667   ⟸   ENSMUST00000201394
RefSeq Acc Id: ENSMUSP00000116292   ⟸   ENSMUST00000136507
RefSeq Acc Id: XP_036020582   ⟸   XM_036164689
- Peptide Label: isoform X1
- UniProtKB: Q5XHW3 (UniProtKB/Swiss-Prot),   A0A6P7R7S5 (UniProtKB/TrEMBL),   A0A8C6GER1 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99LS3-F1-model_v2 AlphaFold Q99LS3 1-225 view protein structure

Promoters
RGD ID:6888186
Promoter ID:EPDNEW_M7544
Type:single initiation site
Name:Psph_2
Description:Mus musculus phosphoserine phosphatase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M7545  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385129,779,125 - 129,779,185EPDNEW
RGD ID:6888188
Promoter ID:EPDNEW_M7545
Type:initiation region
Name:Psph_1
Description:Mus musculus phosphoserine phosphatase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M7544  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385129,787,222 - 129,787,282EPDNEW
RGD ID:6838154
Promoter ID:MM_KWN:44214
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000031399,   ENSMUST00000120496,   OTTMUST00000068492
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365130,284,784 - 130,285,284 (-)MPROMDB
RGD ID:6838187
Promoter ID:MM_KWN:44215
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000031402,   NM_009838,   NM_133900,   UC008ZTI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365130,291,911 - 130,293,312 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97788 AgrOrtholog
Ensembl Genes ENSMUSG00000029446 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000031399 ENTREZGENE
  ENSMUSP00000031399.7 UniProtKB/Swiss-Prot
  ENSMUSP00000113671.3 UniProtKB/TrEMBL
  ENSMUSP00000116292.3 UniProtKB/TrEMBL
  ENSMUSP00000144667.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000031399 ENTREZGENE
  ENSMUST00000031399.13 UniProtKB/Swiss-Prot
  ENSMUST00000118268.9 UniProtKB/TrEMBL
  ENSMUST00000136507.4 UniProtKB/TrEMBL
  ENSMUST00000201394.4 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1000 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro HAD-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HAD_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSP UniProtKB/Swiss-Prot
KEGG Report mmu:100678 UniProtKB/Swiss-Prot
MGD MGI:97788 ENTREZGENE
NCBI Gene 100678 ENTREZGENE
PANTHER PHOSPHOSERINE PHOSPHATASE UniProtKB/Swiss-Prot
  PHOSPHOSERINE PHOSPHATASE UniProtKB/Swiss-Prot
  PHOSPHOSERINE PHOSPHATASE UniProtKB/TrEMBL
  PHOSPHOSERINE PHOSPHATASE UniProtKB/TrEMBL
Pfam Hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Psph PhenoGen
Superfamily-SCOP SSF56784 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs HAD-SF-IB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  serB UniProtKB/Swiss-Prot
UniProt A0A0J9YVH9_MOUSE UniProtKB/TrEMBL
  A0A6P7R7S5 ENTREZGENE
  A0A8C6GER1 ENTREZGENE
  D3Z4T3_MOUSE UniProtKB/TrEMBL
  D3Z666_MOUSE UniProtKB/TrEMBL
  Q5XHW3 ENTREZGENE
  Q99LS3 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3TI16 UniProtKB/Swiss-Prot
  Q5XHW3 UniProtKB/Swiss-Prot