Crim1 (cysteine rich transmembrane BMP regulator 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Crim1 (cysteine rich transmembrane BMP regulator 1) Mus musculus
Analyze
Symbol: Crim1
Name: cysteine rich transmembrane BMP regulator 1
RGD ID: 1318642
MGI Page MGI
Description: Predicted to enable PDZ domain binding activity. Predicted to act upstream of or within negative regulation of BMP signaling pathway. Predicted to be located in extracellular region and membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; heart; integumental system; and sensory organ. Orthologous to human CRIM1 (cysteine rich transmembrane BMP regulator 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AU015004; CRIM-1; cysteine rich transmembrane BMP regulator 1 (chordin like); cysteine-rich motor neuron 1 protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391778,507,602 - 78,684,021 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1778,507,677 - 78,684,021 (+)EnsemblGRCm39 Ensembl
GRCm381778,200,233 - 78,376,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1778,200,248 - 78,376,592 (+)EnsemblGRCm38mm10GRCm38
MGSCv371778,599,588 - 78,775,932 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361778,102,126 - 78,279,372 (+)NCBIMGSCv36mm8
Celera1782,502,178 - 82,678,529 (+)NCBICelera
Cytogenetic Map17E2- E3NCBI
cM Map1748.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-fluorouracil  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
caffeine  (ISO)
carbamazepine  (ISO)
chloroprene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (ISO)
cyclosporin A  (EXP,ISO)
DDT  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
diethylstilbestrol  (ISO)
disulfiram  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
endosulfan  (ISO)
enniatin  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
flutamide  (ISO)
folic acid  (EXP)
gamma-hexachlorocyclohexane  (ISO)
gentamycin  (ISO)
graphene oxide  (ISO)
inulin  (EXP)
irinotecan  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-diethyl-m-toluamide  (ISO)
nickel sulfate  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
permethrin  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
prednisolone  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
succimer  (EXP,ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal basal lamina morphology  (IAGP)
abnormal ductus venosus valve morphology  (IEA)
abnormal eye morphology  (IEA)
abnormal eye posterior chamber morphology  (IAGP)
abnormal glomerular capillary endothelium morphology  (IAGP)
abnormal glomerular capillary morphology  (IAGP)
abnormal glomerular filtration barrier function  (IAGP)
abnormal hepatic portal vein connection  (IEA)
abnormal hypoglossal nerve topology  (IEA)
abnormal kidney corticomedullary boundary morphology  (IAGP)
abnormal kidney pelvis morphology  (IAGP)
abnormal Meckel's cartilage morphology  (IEA)
abnormal Mullerian duct topology  (IEA)
abnormal optic cup morphology  (IAGP)
abnormal peritubular capillary endothelium morphology  (IAGP)
abnormal peritubular capillary morphology  (IAGP)
abnormal podocyte foot process morphology  (IAGP)
abnormal podocyte morphology  (IAGP)
abnormal renal filtration rate  (IAGP)
abnormal renal glomerulus basement membrane morphology  (IAGP)
abnormal renal glomerulus morphology  (IAGP)
abnormal renin activity  (IAGP)
abnormal rib morphology  (IEA)
abnormal vertebral arch morphology  (IEA)
abnormal vertebral artery topology  (IEA)
abnormal vitelline vein connection  (IEA)
abnormal vitelline vein topology  (IEA)
absent connection between subcutaneous lymph vessels and lymph sac  (IEA)
absent ductus venosus  (IEA)
absent ductus venosus valve  (IEA)
absent glomerular endothelium fenestra  (IAGP)
absent mandibular nerve  (IEA)
absent posterior communicating artery  (IEA)
absent segment of posterior cerebral artery  (IEA)
albuminuria  (IAGP)
anal atresia  (IEA)
anastomosis between internal carotid artery and basilar artery  (IEA)
aortic arch coarctation  (IEA)
bleb  (IAGP)
blood in lymph vessels  (IEA)
cerebral edema  (IAGP)
cortical renal glomerulopathies  (IAGP)
decreased parotid gland size  (IEA)
decreased podocyte number  (IAGP)
decreased renal glomerular filtration rate  (IAGP)
decreased renal glomerulus basement membrane thickness  (IAGP)
decreased survivor rate  (IAGP)
dilated glomerular capillary  (IAGP)
dilated renal tubule  (IAGP)
edema  (IAGP)
fetal bleb  (IAGP)
fragmented Meckel's cartilage  (IEA)
fused dorsal root ganglion  (IEA)
fusion of vertebral arches  (IEA)
glomerulosclerosis  (IAGP)
glomerulus hemorrhage  (IAGP)
hematoma  (IAGP)
herniated liver  (IEA)
hydronephrosis  (IAGP)
impaired ureteric peristalsis  (IAGP)
increased glomerular capsule space  (IAGP)
increased kidney apoptosis  (IAGP)
increased renal glomerulus basement membrane thickness  (IAGP)
increased vascular permeability  (IAGP)
kidney cortex cyst  (IAGP)
kidney inflammation  (IAGP)
kidney papillary atrophy  (IAGP)
kidney papillary hypoplasia  (IAGP)
lens dislocation  (IEA)
lethality, incomplete penetrance  (IAGP)
mesangiolysis  (IAGP)
microphthalmia  (IAGP)
muscular ventricular septal defect  (IEA)
no abnormal phenotype detected  (IAGP)
perimembraneous ventricular septal defect  (IEA)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
podocyte foot process effacement  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
pulmonary vein hypoplasia  (IEA)
renal glomerulus cyst  (IAGP)
renal glomerulus hypertrophy  (IAGP)
renal hypoplasia  (IAGP)
renal interstitial fibrosis  (IAGP)
renal tubular necrosis  (IAGP)
retrolental blood  (IEA)
short kidney papilla  (IAGP)
small kidney  (IAGP)
small lens  (IAGP)
subcutaneous edema  (IEA)
syndactyly  (IAGP)
telangiectasia  (IEA)
trunk curl  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10642437   PMID:10842084   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11084657   PMID:11242070   PMID:12464430   PMID:12477932   PMID:12520002   PMID:12805376  
PMID:15489334   PMID:15664173   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16157277   PMID:16284245   PMID:16602821   PMID:17106887   PMID:17460146   PMID:18215621   PMID:18287559  
PMID:18957218   PMID:19228596   PMID:19776720   PMID:20562862   PMID:20615956   PMID:21220699   PMID:21267068   PMID:21862448   PMID:21873635   PMID:22225908   PMID:22488641   PMID:22511315  
PMID:23209302   PMID:23224993   PMID:23341629   PMID:24353059   PMID:25561690   PMID:26681494   PMID:26800422   PMID:26821812   PMID:27100196   PMID:27803996   PMID:29539633   PMID:30973865  
PMID:31776724   PMID:33953184   PMID:34321999   PMID:34686320   PMID:34686337   PMID:35065713   PMID:36823038   PMID:36934325   PMID:38355793  


Genomics

Comparative Map Data
Crim1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391778,507,602 - 78,684,021 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1778,507,677 - 78,684,021 (+)EnsemblGRCm39 Ensembl
GRCm381778,200,233 - 78,376,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1778,200,248 - 78,376,592 (+)EnsemblGRCm38mm10GRCm38
MGSCv371778,599,588 - 78,775,932 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361778,102,126 - 78,279,372 (+)NCBIMGSCv36mm8
Celera1782,502,178 - 82,678,529 (+)NCBICelera
Cytogenetic Map17E2- E3NCBI
cM Map1748.09NCBI
CRIM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38236,355,778 - 36,551,135 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl236,355,778 - 36,551,135 (+)EnsemblGRCh38hg38GRCh38
GRCh37236,582,921 - 36,778,278 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36236,436,901 - 36,631,782 (+)NCBINCBI36Build 36hg18NCBI36
Build 34236,495,047 - 36,689,928NCBI
Celera236,424,733 - 36,619,370 (+)NCBICelera
Cytogenetic Map2p22.2NCBI
HuRef236,324,018 - 36,518,565 (+)NCBIHuRef
CHM1_1236,512,729 - 36,707,637 (+)NCBICHM1_1
T2T-CHM13v2.0236,362,433 - 36,557,798 (+)NCBIT2T-CHM13v2.0
Crim1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8622,447,983 - 22,622,459 (-)NCBIGRCr8
mRatBN7.2616,695,864 - 16,870,264 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,697,829 - 16,870,259 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx617,006,372 - 17,178,832 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0617,328,581 - 17,501,056 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,812,112 - 16,987,170 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06788,490 - 962,663 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6788,548 - 960,703 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06780,568 - 954,493 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46962,024 - 1,141,314 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.161,051,003 - 1,141,914 (+)NCBI
Celera616,341,369 - 16,513,685 (-)NCBICelera
Cytogenetic Map6q12NCBI
Crim1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554414,274,611 - 4,420,537 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554414,275,411 - 4,420,537 (+)NCBIChiLan1.0ChiLan1.0
CRIM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21289,927,033 - 90,122,274 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A89,931,009 - 90,126,247 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A36,384,964 - 36,580,214 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A37,148,551 - 37,342,933 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A37,147,108 - 37,340,537 (+)Ensemblpanpan1.1panPan2
CRIM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11728,857,702 - 29,042,399 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1728,857,696 - 29,040,002 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1728,671,528 - 28,856,142 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01729,507,397 - 29,692,213 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1729,506,861 - 29,692,195 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11728,729,097 - 28,913,813 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01728,797,081 - 28,981,634 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01729,016,015 - 29,200,891 (+)NCBIUU_Cfam_GSD_1.0
Crim1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629242,958,263 - 43,137,956 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366631,623,355 - 1,803,448 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366631,623,655 - 1,803,442 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRIM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3103,612,659 - 103,815,556 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13103,612,231 - 103,815,493 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23110,257,604 - 110,477,270 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CRIM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11470,868,523 - 71,067,086 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1470,870,839 - 71,067,215 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604540,894,800 - 41,091,278 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Crim1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473818,035,725 - 18,216,464 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473818,036,199 - 18,216,086 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Crim1
7578 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:842
Count of miRNA genes:473
Interacting mature miRNAs:598
Transcripts:ENSMUST00000112498
Prediction methods:Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141758Pstc5_mperiosteal circumference 5 (mouse)Not determined175710765191107803Mouse
4142201Obrq15_mobesity resistance QTL 15 (mouse)Not determined5753444780885776Mouse
4141879Chlq9_mcirculating hormone level QTL 9 (mouse)Not determined175175842585758612Mouse
1357532Bmch7_mbone mechanical trait 7 (mouse)Not determined175175842585758612Mouse
11528551Sluc32_msusceptibility to lung cancer 32 (mouse)176230101095294699Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
12910536Nrq8a_mnoise-induced hearing loss resistant QTL 8a (mouse)175710765191107803Mouse
1357528Nhdlq3_mnon-HDL QTL 3 (mouse)Not determined177339513295294699Mouse
12910537Nrq8_mnoise-induced hearing loss resistant QTL 8 (mouse)175710765191107803Mouse
4141040Hmtb9_mhemostasis and thrombosis rebleeding time 9 (mouse)Not determined5758908991589197Mouse
4142256Nilac12_mnicotine induced locomotor activity 12 (mouse)Not determined176894131995294699Mouse
1302017Aliq3_macute lung injury QTL 3 (mouse)Not determined176388554895294699Mouse
1357447Heal13_mwound healing/regeneration 13 (mouse)Not determined175710765191107803Mouse
26884428Cvht3_mcranial vault height 3, 5 week (mouse)174651092682407429Mouse
14928308Manh82_mmandible shape 82 (mouse)176631524395294699Mouse
1357646Axtq3_manxiety QTL 3 (mouse)Not determined177458908990395270Mouse
1301107Scc4_mcolon tumor susceptibility 4 (mouse)Not determined176230101095294699Mouse
11039498Ltpr7b_mLeishmania tropica response 7b (mouse)177070119895294699Mouse
11039499Ltpr7a_mLeishmania tropica response 7a (mouse)177070119895294699Mouse
11039500Ltpr7c_mLeishmania tropica response 7c (mouse)177070119895294699Mouse
1357552Aaj4_manxiety in A/J 4 (mouse)Not determined177458908990395270Mouse
4141011Bmd26_mbone mineral density 26 (mouse)Not determined175710765191107803Mouse
1300735Pgia20_mproteoglycan induced arthritis 20 (mouse)Not determined175710765191107803Mouse
1357754Ahl3_mage related hearing loss 3 (mouse)Not determined175020395784204103Mouse
4142414Pregq4_mpregnancy QTL 4 (mouse)Not determined175753444793507179Mouse
11039514Ltpr7_mLeishmania tropica response 7 (mouse)177070119895294699Mouse
1301728Ffal1_mfree fatty acid level 1 (mouse)Not determined176521493895294699Mouse
13464254Ifvrq3_minfluenza virus resistance QTL 3 (mouse)176795765583908089Mouse
4141195Nilac11_mnicotine induced locomotor activity 11 (mouse)Not determined177339513295294699Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
4141697Hbnr3_mHeligmosomoides bakeri nematode resistance 3 (mouse)Not determined7410765193507179Mouse

Markers in Region
AU021760  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381778,311,717 - 78,311,920UniSTSGRCm38
MGSCv371778,711,057 - 78,711,260UniSTSGRCm37
Celera1782,613,621 - 82,613,824UniSTS
Cytogenetic Map17E2-E3UniSTS
Whitehead/MRC_RH17931.1UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001414256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_015800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006524602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006524603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC103598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02079738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF168680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK018666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC100348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000112498   ⟹   ENSMUSP00000108117
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1778,507,677 - 78,684,021 (+)Ensembl
GRCm38.p6 Ensembl1778,200,248 - 78,376,592 (+)Ensembl
Ensembl Acc Id: ENSMUST00000234059   ⟹   ENSMUSP00000157204
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1778,587,612 - 78,651,935 (+)Ensembl
GRCm38.p6 Ensembl1778,280,183 - 78,344,506 (+)Ensembl
Ensembl Acc Id: ENSMUST00000234439   ⟹   ENSMUSP00000157111
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1778,658,318 - 78,681,607 (+)Ensembl
GRCm38.p6 Ensembl1778,350,889 - 78,374,178 (+)Ensembl
Ensembl Acc Id: ENSMUST00000234546   ⟹   ENSMUSP00000157312
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1778,508,348 - 78,620,617 (+)Ensembl
GRCm38.p6 Ensembl1778,200,919 - 78,313,188 (+)Ensembl
Ensembl Acc Id: ENSMUST00000234700   ⟹   ENSMUSP00000157299
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1778,508,494 - 78,681,711 (+)Ensembl
GRCm38.p6 Ensembl1778,201,065 - 78,374,282 (+)Ensembl
Ensembl Acc Id: ENSMUST00000234964   ⟹   ENSMUSP00000156992
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1778,545,201 - 78,623,039 (+)Ensembl
GRCm38.p6 Ensembl1778,237,772 - 78,315,610 (+)Ensembl
RefSeq Acc Id: NM_001414256   ⟹   NP_001401185
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391778,507,677 - 78,684,021 (+)NCBI
RefSeq Acc Id: NM_015800   ⟹   NP_056615
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391778,507,677 - 78,684,021 (+)NCBI
GRCm381778,200,248 - 78,376,592 (+)NCBI
MGSCv371778,599,588 - 78,775,932 (+)RGD
Celera1782,502,178 - 82,678,529 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006524602   ⟹   XP_006524665
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391778,507,602 - 78,684,021 (+)NCBI
GRCm381778,200,233 - 78,376,592 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006524603   ⟹   XP_006524666
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391778,587,402 - 78,684,021 (+)NCBI
GRCm381778,279,973 - 78,376,592 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030249892   ⟹   XP_030105752
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391778,508,173 - 78,684,021 (+)NCBI
GRCm381778,200,744 - 78,376,592 (+)NCBI
Sequence:
RefSeq Acc Id: NP_056615   ⟸   NM_015800
- Peptide Label: isoform 1 precursor
- UniProtKB: Q497W4 (UniProtKB/Swiss-Prot),   Q9JLL0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006524665   ⟸   XM_006524602
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006524666   ⟸   XM_006524603
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_030105752   ⟸   XM_030249892
- Peptide Label: isoform X4
Ensembl Acc Id: ENSMUSP00000108117   ⟸   ENSMUST00000112498
Ensembl Acc Id: ENSMUSP00000157299   ⟸   ENSMUST00000234700
Ensembl Acc Id: ENSMUSP00000156992   ⟸   ENSMUST00000234964
Ensembl Acc Id: ENSMUSP00000157111   ⟸   ENSMUST00000234439
Ensembl Acc Id: ENSMUSP00000157312   ⟸   ENSMUST00000234546
Ensembl Acc Id: ENSMUSP00000157204   ⟸   ENSMUST00000234059
RefSeq Acc Id: NP_001401185   ⟸   NM_001414256
- Peptide Label: isoform 2 precursor
Protein Domains
Antistasin-like   Cysteine-rich motor neuron 1 protein C-terminal   IGFBP N-terminal   VWFC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JLL0-F1-model_v2 AlphaFold Q9JLL0 1-1037 view protein structure

Promoters
RGD ID:13676790
Promoter ID:EPDNEW_M22544
Type:initiation region
Name:Crim1_1
Description:Mus musculus cysteine rich transmembrane BMP regulator 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381778,200,248 - 78,200,308EPDNEW
RGD ID:6827950
Promoter ID:MM_KWN:24223
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000112498
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361778,599,621 - 78,600,542 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1354756 AgrOrtholog
Ensembl Genes ENSMUSG00000024074 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000112498 ENTREZGENE
  ENSMUST00000112498.3 UniProtKB/Swiss-Prot
  ENSMUST00000234059.2 UniProtKB/TrEMBL
  ENSMUST00000234439.2 UniProtKB/TrEMBL
  ENSMUST00000234546.2 UniProtKB/TrEMBL
  ENSMUST00000234700.2 UniProtKB/TrEMBL
  ENSMUST00000234964.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.40.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.20.200.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Antistasin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRIM1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRIM1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hirudin/antistatin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWF_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:50766 UniProtKB/Swiss-Prot
MGD MGI:1354756 ENTREZGENE
NCBI Gene 50766 ENTREZGENE
PANTHER CYSTEINE-RICH MOTOR NEURON 1 PROTEIN UniProtKB/Swiss-Prot
  CYSTEINE-RICH MOTOR NEURON 1 PROTEIN UniProtKB/Swiss-Prot
  CYSTEINE-RICH MOTOR NEURON 1 PROTEIN UniProtKB/TrEMBL
  CYSTEINE-RICH MOTOR NEURON 1 PROTEIN UniProtKB/TrEMBL
Pfam Antistasin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRIM1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP UniProtKB/Swiss-Prot
  VWC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Crim1 PhenoGen
PROSITE ANTISTASIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP_N_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWFC_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWFC_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00121 UniProtKB/Swiss-Prot
  VWC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWC_out UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP FnI-like domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57184 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57262 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A3Q4EBT2_MOUSE UniProtKB/TrEMBL
  A0A3Q4EGH7_MOUSE UniProtKB/TrEMBL
  A0A3Q4EHS8_MOUSE UniProtKB/TrEMBL
  A0A3Q4EIC0_MOUSE UniProtKB/TrEMBL
  A0A3Q4EID5_MOUSE UniProtKB/TrEMBL
  CRIM1_MOUSE UniProtKB/Swiss-Prot
  Q3TWP4_MOUSE UniProtKB/TrEMBL
  Q497W4 ENTREZGENE
  Q8BS96_MOUSE UniProtKB/TrEMBL
  Q9JLL0 ENTREZGENE
UniProt Secondary Q497W4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-04 Crim1  cysteine rich transmembrane BMP regulator 1  Crim1  cysteine rich transmembrane BMP regulator 1 (chordin like)  Symbol and/or name change 5135510 APPROVED