Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Cdk2ap1 | Mouse | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of CDK2AP1 mRNA] | CTD | PMID:22206623 | Cdk2ap1 | Mouse | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of CDK2AP1 mRNA | CTD | PMID:22206623 | Cdk2ap1 | Mouse | 17alpha-ethynylestradiol | increases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in increased expression of CDK2AP1 mRNA | CTD | PMID:17108234 | Cdk2ap1 | Mouse | 17beta-estradiol | increases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of CDK2AP1 mRNA | CTD | PMID:32145629 | Cdk2ap1 | Mouse | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | increases expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | Metribolone results in increased expression of CDK2AP1 mRNA | CTD | PMID:17010196 | Cdk2ap1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of CDK2AP1 mRNA | CTD | PMID:24680724 | Cdk2ap1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CDK2AP1 mRNA | CTD | PMID:34747641 | Cdk2ap1 | Mouse | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of CDK2AP1 mRNA | CTD | PMID:18648102 | Cdk2ap1 | Mouse | 6-propyl-2-thiouracil | increases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of CDK2AP1 mRNA | CTD | PMID:30047161 | Cdk2ap1 | Mouse | aflatoxin B1 | increases expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of CDK2AP1 mRNA | CTD | PMID:22100608 | Cdk2ap1 | Mouse | all-trans-retinoic acid | decreases expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of CDK2AP1 mRNA | CTD | PMID:33167477 | Cdk2ap1 | Mouse | amitrole | increases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of CDK2AP1 mRNA | CTD | PMID:30047161 | Cdk2ap1 | Mouse | antirheumatic drug | increases expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of CDK2AP1 mRNA | CTD | PMID:24449571 | Cdk2ap1 | Mouse | arsenite(3-) | multiple interactions | ISO | CDK2AP1 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to CDK2AP1 mRNA] | CTD | PMID:32406909 | Cdk2ap1 | Mouse | atrazine | decreases expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of CDK2AP1 mRNA | CTD | PMID:22378314 | Cdk2ap1 | Mouse | benzo[a]pyrene | affects methylation | ISO | CDK2AP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of CDK2AP1 promoter | CTD | PMID:27901495 | Cdk2ap1 | Mouse | bisphenol A | affects expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of CDK2AP1 mRNA | CTD | PMID:25181051 | Cdk2ap1 | Mouse | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CDK2AP1 mRNA | CTD | PMID:35598803 | Cdk2ap1 | Mouse | bisphenol A | multiple interactions | ISO | CDK2AP1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CDK2AP1 gene | CTD | PMID:31601247 | Cdk2ap1 | Mouse | bisphenol A | increases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of CDK2AP1 mRNA | CTD | PMID:32145629 | Cdk2ap1 | Mouse | bisphenol A | affects expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | bisphenol A affects the expression of CDK2AP1 mRNA | CTD | PMID:30903817 | Cdk2ap1 | Mouse | C60 fullerene | decreases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | fullerene C60 results in decreased expression of CDK2AP1 mRNA | CTD | PMID:19167457 | Cdk2ap1 | Mouse | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Cdk2ap1 | Mouse | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of CDK2AP1 mRNA | CTD | PMID:28472532 | Cdk2ap1 | Mouse | cisplatin | increases expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of CDK2AP1 mRNA | CTD | PMID:19561079 and PMID:27594783 | Cdk2ap1 | Mouse | cobalt dichloride | decreases expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of CDK2AP1 mRNA | CTD | PMID:19320972 | Cdk2ap1 | Mouse | cobalt dichloride | decreases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | cobaltous chloride results in decreased expression of CDK2AP1 mRNA | CTD | PMID:24386269 | Cdk2ap1 | Mouse | cyclosporin A | decreases expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of CDK2AP1 mRNA | CTD | PMID:25562108 and PMID:27989131 | Cdk2ap1 | Mouse | cyclosporin A | decreases methylation | ISO | CDK2AP1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of CDK2AP1 promoter | CTD | PMID:27989131 | Cdk2ap1 | Mouse | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of CDK2AP1 mRNA | CTD | PMID:17361019 and PMID:21266533 | Cdk2ap1 | Mouse | finasteride | increases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | Finasteride results in increased expression of CDK2AP1 mRNA | CTD | PMID:24136188 | Cdk2ap1 | Mouse | flutamide | increases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of CDK2AP1 mRNA | CTD | PMID:24136188 | Cdk2ap1 | Mouse | folic acid | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of CDK2AP1 mRNA] | CTD | PMID:22206623 | Cdk2ap1 | Mouse | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of CDK2AP1 mRNA | CTD | PMID:25629700 | Cdk2ap1 | Mouse | fulvestrant | multiple interactions | ISO | CDK2AP1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CDK2AP1 gene | CTD | PMID:31601247 | Cdk2ap1 | Mouse | glafenine | increases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | Glafenine results in increased expression of CDK2AP1 mRNA | CTD | PMID:24136188 | Cdk2ap1 | Mouse | methimazole | increases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of CDK2AP1 mRNA | CTD | PMID:30047161 | Cdk2ap1 | Mouse | nickel dichloride | affects expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | nickel chloride affects the expression of CDK2AP1 mRNA | CTD | PMID:22546817 | Cdk2ap1 | Mouse | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of CDK2AP1 mRNA | CTD | PMID:17562736 | Cdk2ap1 | Mouse | paracetamol | decreases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of CDK2AP1 mRNA | CTD | PMID:33387578 | Cdk2ap1 | Mouse | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of CDK2AP1 mRNA | CTD | PMID:23892564 | Cdk2ap1 | Mouse | phenobarbital | increases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | Phenobarbital results in increased expression of CDK2AP1 mRNA | CTD | PMID:30047161 | Cdk2ap1 | Mouse | PhIP | increases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of CDK2AP1 mRNA | CTD | PMID:15215175 | Cdk2ap1 | Mouse | pinosylvin | decreases expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | pinosylvin results in decreased expression of CDK2AP1 mRNA | CTD | PMID:23333577 | Cdk2ap1 | Mouse | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of CDK2AP1 mRNA | CTD | PMID:23811191 | Cdk2ap1 | Mouse | propiconazole | increases expression | EXP | | 6480464 | propiconazole results in increased expression of CDK2AP1 mRNA | CTD | PMID:21278054 | Cdk2ap1 | Mouse | sodium arsenite | increases expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of CDK2AP1 mRNA | CTD | PMID:34032870 | Cdk2ap1 | Mouse | sulfadimethoxine | increases expression | ISO | Cdk2ap1 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of CDK2AP1 mRNA | CTD | PMID:30047161 | Cdk2ap1 | Mouse | temozolomide | increases expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of CDK2AP1 mRNA | CTD | PMID:31758290 | Cdk2ap1 | Mouse | trans-pinosylvin | decreases expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | pinosylvin results in decreased expression of CDK2AP1 mRNA | CTD | PMID:23333577 | Cdk2ap1 | Mouse | Tributyltin oxide | decreases expression | EXP | | 6480464 | bis(tri-n-butyltin)oxide results in decreased expression of CDK2AP1 mRNA | CTD | PMID:18958704 | Cdk2ap1 | Mouse | trimellitic anhydride | increases expression | EXP | | 6480464 | trimellitic anhydride results in increased expression of CDK2AP1 mRNA | CTD | PMID:19042947 | Cdk2ap1 | Mouse | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of CDK2AP1 mRNA | CTD | PMID:33045310 | Cdk2ap1 | Mouse | tungsten | increases expression | EXP | | 6480464 | Tungsten results in increased expression of CDK2AP1 mRNA | CTD | PMID:30912803 | Cdk2ap1 | Mouse | valproic acid | increases methylation | ISO | CDK2AP1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of CDK2AP1 gene | CTD | PMID:29154799 | Cdk2ap1 | Mouse | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of CDK2AP1 mRNA | CTD | PMID:20546886 and PMID:21427059 | Cdk2ap1 | Mouse | valproic acid | affects expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CDK2AP1 mRNA | CTD | PMID:25979313 | Cdk2ap1 | Mouse | valproic acid | decreases expression | ISO | CDK2AP1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of CDK2AP1 mRNA | CTD | PMID:28001369 and PMID:29154799 | |