Rbx1 (ring-box 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Rbx1 (ring-box 1) Mus musculus
Analyze
Symbol: Rbx1
Name: ring-box 1
RGD ID: 1318230
MGI Page MGI
Description: Predicted to enable several functions, including cullin family protein binding activity; ubiquitin protein ligase binding activity; and ubiquitin-like protein ligase activity. Predicted to contribute to ubiquitin-protein transferase activity. Involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular response to UV; and protein ubiquitination. Acts upstream of or within protein K48-linked ubiquitination; protein catabolic process; and protein monoubiquitination. Located in cytosol. Part of Cul4A-RING E3 ubiquitin ligase complex and SCF ubiquitin ligase complex. Is expressed in several structures, including genitourinary system. Orthologous to human RBX1 (ring-box 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1500002P15Rik; AA517855; E3 ubiquitin-protein ligase RBX1; E3 ubiquitin-protein transferase RBX1; RIKEN cDNA 1500002P15 gene; RING finger protein 75; RING-box protein 1; RO; ROC1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Rbx1-ps  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,350,517 - 81,360,570 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1581,350,497 - 81,360,570 (+)EnsemblGRCm39 Ensembl
GRCm381581,466,316 - 81,476,369 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,466,296 - 81,476,369 (+)EnsemblGRCm38mm10GRCm38
MGSCv371581,296,746 - 81,306,799 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361581,293,628 - 81,303,619 (+)NCBIMGSCv36mm8
Celera1583,584,172 - 83,594,608 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-acetamidofluorene  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (ISO)
antimycin A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calycosin  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
deguelin  (ISO)
dibenzo[a,l]pyrene  (EXP)
Dibutyl phosphate  (ISO)
diclofenac  (EXP)
dicrotophos  (ISO)
dinophysistoxin 1  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
fenofibrate  (EXP)
ferroheme b  (EXP)
finasteride  (ISO)
fipronil  (ISO)
flutamide  (ISO)
folic acid  (EXP)
heme b  (EXP)
hypochlorous acid  (EXP)
ivermectin  (ISO)
leflunomide  (ISO)
maneb  (EXP)
methimazole  (ISO)
nefazodone  (ISO)
nimesulide  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pinosylvin  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
pyrimidifen  (ISO)
sertraline  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
solanesol  (ISO)
sulindac  (ISO)
tamoxifen  (EXP)
tebufenpyrad  (ISO)
thifluzamide  (ISO)
titanium dioxide  (EXP)
trans-pinosylvin  (ISO)
trovafloxacin  (EXP)
urethane  (ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Hayes JD and Dinkova-Kostova AT, Trends Biochem Sci. 2014 Apr;39(4):199-218. doi: 10.1016/j.tibs.2014.02.002. Epub 2014 Mar 16.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Identification of candidate lung cancer susceptibility genes in mouse using oligonucleotide arrays. Lemon WJ, etal., J Med Genet 2002 Sep;39(9):644-55.
4. Expanding role of ubiquitination in NF-kappaB signaling. Liu S and Chen ZJ, Cell Res. 2011 Jan;21(1):6-21. Epub 2010 Dec 7.
5. Multiple roles of Rbx1 in the VBC-Cul2 ubiquitin ligase complex. Megumi Y, etal., Genes Cells. 2005 Jul;10(7):679-91.
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. Nedd8 on cullin: building an expressway to protein destruction. Pan ZQ, etal., Oncogene. 2004 Mar 15;23(11):1985-97.
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Regulation of oxygen homeostasis by hypoxia-inducible factor 1. Semenza GL Physiology (Bethesda). 2009 Apr;24:97-106.
Additional References at PubMed
PMID:8889548   PMID:10213691   PMID:10213692   PMID:10230407   PMID:10349636   PMID:10643962   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11337588   PMID:11384984   PMID:12140560  
PMID:12417738   PMID:12477932   PMID:12520002   PMID:12939278   PMID:14610273   PMID:14960280   PMID:15489334   PMID:15601820   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16275325  
PMID:16602821   PMID:16880526   PMID:18287559   PMID:18799693   PMID:18826954   PMID:19037258   PMID:19325126   PMID:19398581   PMID:19576224   PMID:20352047   PMID:20452971   PMID:21245377  
PMID:21343341   PMID:21368834   PMID:21677750   PMID:21873635   PMID:22020328   PMID:22024926   PMID:22033112   PMID:22118460   PMID:22405651   PMID:22822056   PMID:23274085   PMID:23707388  
PMID:23871831   PMID:23874827   PMID:23955342   PMID:23990666   PMID:24210661   PMID:24357321   PMID:24793696   PMID:27113764   PMID:27325702   PMID:28481879   PMID:28530236   PMID:29472293  
PMID:29593216   PMID:32325033   PMID:34526721   PMID:35641500   PMID:36114006   PMID:37639640  


Genomics

Comparative Map Data
Rbx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,350,517 - 81,360,570 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1581,350,497 - 81,360,570 (+)EnsemblGRCm39 Ensembl
GRCm381581,466,316 - 81,476,369 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,466,296 - 81,476,369 (+)EnsemblGRCm38mm10GRCm38
MGSCv371581,296,746 - 81,306,799 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361581,293,628 - 81,303,619 (+)NCBIMGSCv36mm8
Celera1583,584,172 - 83,594,608 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.11NCBI
RBX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382240,951,378 - 40,973,309 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2240,951,347 - 40,973,309 (+)EnsemblGRCh38hg38GRCh38
GRCh372241,347,382 - 41,369,313 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362239,677,331 - 39,698,614 (+)NCBINCBI36Build 36hg18NCBI36
Build 342239,671,884 - 39,693,168NCBI
Celera2225,151,059 - 25,172,347 (+)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2224,308,951 - 24,330,592 (+)NCBIHuRef
CHM1_12241,306,113 - 41,327,855 (+)NCBICHM1_1
T2T-CHM13v2.02241,423,571 - 41,445,506 (+)NCBIT2T-CHM13v2.0
Rbx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87114,870,893 - 114,881,194 (+)NCBIGRCr8
mRatBN7.27112,976,863 - 113,001,051 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7112,990,835 - 113,001,051 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7114,753,189 - 114,763,404 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07116,976,687 - 116,986,902 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07116,946,098 - 116,956,313 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07122,700,849 - 122,710,907 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7122,700,854 - 122,709,935 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07122,677,395 - 122,687,076 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47119,794,976 - 119,805,104 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17119,828,667 - 119,836,146 (+)NCBI
Celera7109,310,166 - 109,320,235 (+)NCBICelera
Cytogenetic Map7q34NCBI
Rbx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541326,579,759 - 26,592,980 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541326,579,759 - 26,592,980 (+)NCBIChiLan1.0ChiLan1.0
RBX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22350,781,027 - 50,802,296 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12253,480,935 - 53,503,770 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02221,845,351 - 21,866,627 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12239,941,405 - 39,962,175 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2239,941,405 - 39,962,175 (+)Ensemblpanpan1.1panPan2
RBX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11024,265,733 - 24,280,253 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1024,266,408 - 24,280,235 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1024,200,859 - 24,214,782 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01025,014,111 - 25,028,037 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1025,013,516 - 25,028,019 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11024,729,691 - 24,743,612 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01025,050,324 - 25,064,237 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01025,224,699 - 25,238,847 (-)NCBIUU_Cfam_GSD_1.0
Rbx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049457,861,902 - 7,880,482 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936492873,576 - 890,835 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936492872,316 - 890,860 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl57,500,490 - 7,515,370 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.157,500,492 - 7,515,388 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RBX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11923,500,361 - 23,521,676 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1923,500,356 - 23,522,723 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045101,955,371 - 101,977,480 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247527,546,959 - 7,560,668 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247527,547,702 - 7,560,605 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rbx1
319 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:347
Count of miRNA genes:274
Interacting mature miRNAs:303
Transcripts:ENSMUST00000023036
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
15092079Igly6_mIgG glycosylation 6, GP6 (mouse)157410054082674156Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
15092080Igly7_mIgG glycosylation 7, GP10 (mouse)157779491982674156Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154846536282465496Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1301472Pain1_mpain 1 (mouse)Not determined157532084690813185Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
1301860Gct3_mgranulosa cell tumorigenesis 3 (mouse)Not determined154740959681409691Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse

Markers in Region
RH124284  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381581,475,394 - 81,475,574UniSTSGRCm38
MGSCv371581,305,824 - 81,306,004UniSTSGRCm37
Celera1583,593,633 - 83,593,813UniSTS
Cytogenetic Map15E1UniSTS
UniSTS:237362  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381581,472,963 - 81,473,085UniSTSGRCm38
MGSCv371581,303,393 - 81,303,515UniSTSGRCm37
Celera1583,591,202 - 83,591,324UniSTS
Cytogenetic Map15E1UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_019712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC109153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF140599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK005127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB807275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB522825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ082632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JC212143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000023036   ⟹   ENSMUSP00000023036
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1581,350,497 - 81,360,570 (+)Ensembl
GRCm38.p6 Ensembl1581,466,296 - 81,476,369 (+)Ensembl
Ensembl Acc Id: ENSMUST00000229880
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1581,351,018 - 81,356,404 (+)Ensembl
GRCm38.p6 Ensembl1581,466,817 - 81,472,203 (+)Ensembl
Ensembl Acc Id: ENSMUST00000229991
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1581,357,823 - 81,359,773 (+)Ensembl
GRCm38.p6 Ensembl1581,473,622 - 81,475,572 (+)Ensembl
Ensembl Acc Id: ENSMUST00000230062   ⟹   ENSMUSP00000154877
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1581,350,842 - 81,359,587 (+)Ensembl
GRCm38.p6 Ensembl1581,466,641 - 81,475,386 (+)Ensembl
Ensembl Acc Id: ENSMUST00000230219   ⟹   ENSMUSP00000155288
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1581,350,545 - 81,355,521 (+)Ensembl
GRCm38.p6 Ensembl1581,466,344 - 81,471,320 (+)Ensembl
Ensembl Acc Id: ENSMUST00000231027
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1581,350,996 - 81,352,418 (+)Ensembl
GRCm38.p6 Ensembl1581,466,795 - 81,468,217 (+)Ensembl
RefSeq Acc Id: NM_019712   ⟹   NP_062686
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391581,350,517 - 81,360,570 (+)NCBI
GRCm381581,466,316 - 81,476,369 (+)ENTREZGENE
MGSCv371581,296,746 - 81,306,799 (+)RGD
Celera1583,584,172 - 83,594,608 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_062686   ⟸   NM_019712
- UniProtKB: P62878 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000154877   ⟸   ENSMUST00000230062
Ensembl Acc Id: ENSMUSP00000155288   ⟸   ENSMUST00000230219
Ensembl Acc Id: ENSMUSP00000023036   ⟸   ENSMUST00000023036
Protein Domains
RING-type   Zinc finger RING-H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62878-F1-model_v2 AlphaFold P62878 1-108 view protein structure

Promoters
RGD ID:6826412
Promoter ID:MM_KWN:19155
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000109569,   NM_019712
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361581,296,321 - 81,297,172 (+)MPROMDB
RGD ID:6849064
Promoter ID:MM_XEF:2600
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B6
Transcripts:NM_001018820,   NM_001048314,   NM_001138111,   NM_001161253,   NM_001161254,   NM_114151,   NM_122064,   NM_144356,   NM_209268
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361581,298,346 - 81,298,846 (+)MPROMDB
RGD ID:8684442
Promoter ID:EPDNEW_M20251
Type:multiple initiation site
Name:Rbx1_1
Description:Mus musculus ring-box 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381581,466,348 - 81,466,408EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1891829 AgrOrtholog
Ensembl Genes ENSMUSG00000022400 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000023036 ENTREZGENE
  ENSMUST00000023036.7 UniProtKB/Swiss-Prot
  ENSMUST00000230062.2 UniProtKB/TrEMBL
  ENSMUST00000230219.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro RING-box_E3_Ubiquitin_Ligase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:56438 UniProtKB/Swiss-Prot
MGD MGI:1891829 ENTREZGENE
NCBI Gene Rbx1 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE RBX1-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING BOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam zf-rbx1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rbx1 PhenoGen
PROSITE ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8W6G1_MOUSE UniProtKB/TrEMBL
  A0A2R8W6R3_MOUSE UniProtKB/TrEMBL
  P62878 ENTREZGENE
  Q3TWS3_MOUSE UniProtKB/TrEMBL
  Q3V497_MOUSE UniProtKB/TrEMBL
  Q9D105_MOUSE UniProtKB/TrEMBL
  RBX1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8N6Z8 UniProtKB/Swiss-Prot
  Q9D1S2 UniProtKB/Swiss-Prot
  Q9WUK9 UniProtKB/Swiss-Prot
  Q9Y254 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Rbx1  ring-box 1  1500002P15Rik  RIKEN cDNA 1500002P15 gene  Symbol and/or name change 5135510 APPROVED
2024-08-21 1500002P15Rik  RIKEN cDNA 1500002P15 gene  Rbx1  ring-box 1  Symbol and/or name change 5135510 APPROVED