Hoxd13 (homeobox D13) - Rat Genome Database

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Gene: Hoxd13 (homeobox D13) Mus musculus
Analyze
Symbol: Hoxd13
Name: homeobox D13
RGD ID: 1318173
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Acts upstream of or within several processes, including embryonic digit morphogenesis; morphogenesis of an epithelium; and regulation of branching involved in prostate gland morphogenesis. Located in nucleus. Is expressed in several structures, including genitourinary system; hindgut; limb; limb bud; and tail. Used to study synpolydactyly. Human ortholog(s) of this gene implicated in brachydactyly-syndactyly syndrome; clubfoot; cryptorchidism; and dysostosis (multiple). Orthologous to human HOXD13 (homeobox D13).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: homeo box D13; homeobox protein Hox-4.8; homeobox protein Hox-D13; Hox-4.; Hox-4.8; sp; spdh
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39274,498,569 - 74,501,947 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl274,498,654 - 74,501,943 (+)EnsemblGRCm39 Ensembl
GRCm38274,668,225 - 74,671,603 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl274,668,310 - 74,671,599 (+)EnsemblGRCm38mm10GRCm38
MGSCv37274,506,367 - 74,509,655 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36274,469,149 - 74,470,975 (+)NCBIMGSCv36mm8
Celera276,338,416 - 76,341,706 (+)NCBICelera
Cytogenetic Map2C3NCBI
cM Map244.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anus morphology  (IAGP)
abnormal autopod morphology  (IAGP)
abnormal bone ossification  (IAGP)
abnormal carpal bone morphology  (IAGP)
abnormal digit development  (IAGP)
abnormal digit morphology  (IAGP)
abnormal embryonic autopod plate morphology  (IAGP)
abnormal embryonic tissue morphology  (IAGP)
abnormal fibula morphology  (IAGP)
abnormal forelimb morphology  (IAGP)
abnormal hallux morphology  (IAGP)
abnormal internal anal sphincter morphology  (IAGP)
abnormal limb development  (IAGP)
abnormal metacarpal bone morphology  (IAGP)
abnormal metatarsal bone morphology  (IAGP)
abnormal phalanx morphology  (IAGP)
abnormal prostate gland ventral lobe morphology  (IAGP)
abnormal seminal vesicle morphology  (IAGP)
abnormal smooth muscle morphology  (IAGP)
abnormal tarsal bone morphology  (IAGP)
absent carpal bone  (IAGP)
absent female preputial gland  (IAGP)
absent male preputial gland  (IAGP)
bowed radius  (IAGP)
bowed ulna  (IAGP)
brachydactyly  (IAGP)
brachyphalangia  (IAGP)
brachypodia  (IAGP)
decreased autopod size  (IAGP)
decreased body weight  (IAGP)
decreased embryo size  (IAGP)
decreased metacarpal bone number  (IAGP)
decreased metatarsal bone number  (IAGP)
delayed bone ossification  (IAGP)
delayed endochondral bone ossification  (IAGP)
ectrodactyly  (IAGP)
elongated metatarsal bones  (IAGP)
fused carpal bones  (IAGP)
fused phalanges  (IAGP)
fused tarsal bones  (IAGP)
interdigital webbing  (IAGP)
iris stroma hypoplasia  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
male infertility  (IAGP)
monodactyly  (IAGP)
polydactyly  (IAGP)
polysyndactyly  (IAGP)
postaxial polydactyly  (IAGP)
postnatal lethality  (IAGP)
rectal prolapse  (IAGP)
reduced male fertility  (IAGP)
sacral vertebral fusion  (IAGP)
short limbs  (IAGP)
short metacarpal bones  (IAGP)
short metatarsal bones  (IAGP)
short radius  (IAGP)
short ulna  (IAGP)
syndactyly  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Genomic structure of HOXD13 gene: a nine polyalanine duplication causes synpolydactyly in two unrelated families. Akarsu AN, etal., Hum Mol Genet. 1996 Jul;5(7):945-52.
2. The mouse Hoxd13(spdh) mutation, a polyalanine expansion similar to human type II synpolydactyly (SPD), disrupts the function but not the expression of other Hoxd genes. Bruneau S, etal., Dev Biol. 2001 Sep 15;237(2):345-53.
3. An I47L substitution in the HOXD13 homeodomain causes a novel human limb malformation by producing a selective loss of function. Caronia G, etal., Development. 2003 Apr;130(8):1701-12.
4. Mutation analysis of HOXD13 gene in a Chinese pedigree with synpolydactyly. Dai L, etal., Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2005 Jun;22(3):277-80.
5. Synpolydactyly phenotypes correlate with size of expansions in HOXD13 polyalanine tract. Goodman FR, etal., Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7458-63.
6. Isolated brachydactyly type E caused by a HOXD13 nonsense mutation: a case report. Jamsheer A, etal., BMC Med Genet. 2012 Jan 10;13:4. doi: 10.1186/1471-2350-13-4.
7. Missense mutations in the homeodomain of HOXD13 are associated with brachydactyly types D and E. Johnson D, etal., Am J Hum Genet. 2003 Apr;72(4):984-97. Epub 2003 Mar 14.
8. A nonsense mutation in the HOXD13 gene underlies synpolydactyly with incomplete penetrance. Kurban M, etal., J Hum Genet. 2011 Oct;56(10):701-6. doi: 10.1038/jhg.2011.84. Epub 2011 Aug 4.
9. Sonic hedgehog, BMP4, and Hox genes in the development of anorectal malformations in Ethylenethiourea-exposed fetal rats. Mandhan P, etal., J Pediatr Surg. 2006 Dec;41(12):2041-5.
10. MGDs mouse GO annotations MGD data from the GO Consortium
11. MGD IEA MGD IEA
12. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
13. Mouse MP Annotation Import Pipeline RGD automated import pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. A splice donor site mutation in HOXD13 underlies synpolydactyly with cortical bone thinning. Shi X, etal., Gene. 2013 Dec 15;532(2):297-301. doi: 10.1016/j.gene.2013.09.040. Epub 2013 Sep 18.
17. A novel non-synonymous mutation in the homeodomain of HOXD13 causes synpolydactyly in a Chinese family. Wang B, etal., Clin Chim Acta. 2012 Jul 11;413(13-14):1049-52. doi: 10.1016/j.cca.2012.02.015. Epub 2012 Feb 22.
18. Exome sequencing identifies a novel nonsense mutation of HOXD13 in a Chinese family with synpolydactyly. Wang B, etal., Congenit Anom (Kyoto). 2017 Jan;57(1):4-7. doi: 10.1111/cga.12173.
19. A hypermorphic mouse Gli3 allele results in a polydactylous limb phenotype. Wang C, etal., Dev Dyn. 2007 Mar;236(3):769-76.
20. [Analysis of association between 5' HOXD gene and idiopathic congenital talipes equinovarus]. Wang LL, etal., Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2005 Dec;22(6):653-6.
21. Allelic variants in HOX genes in cryptorchidism. Wang Y, etal., Birth Defects Res A Clin Mol Teratol. 2007 Apr;79(4):269-75.
22. Mutations in HOXD13 underlie syndactyly type V and a novel brachydactyly-syndactyly syndrome. Zhao X, etal., Am J Hum Genet. 2007 Feb;80(2):361-71. Epub 2007 Jan 3.
23. A novel mutation outside homeodomain of HOXD13 causes synpolydactyly in a Chinese family. Zhou X, etal., Bone. 2013 Nov;57(1):237-41. doi: 10.1016/j.bone.2013.07.039. Epub 2013 Aug 12.
24. Maternal exposure to di-n-butyl phthalate (DBP) induces combined anorectal and urogenital malformations in male rat offspring. Zhu YP, etal., Reprod Toxicol. 2016 Jun;61:169-76. doi: 10.1016/j.reprotox.2016.04.007. Epub 2016 Apr 11.
Additional References at PubMed
PMID:1358459   PMID:1680771   PMID:1685889   PMID:2493644   PMID:7490883   PMID:7579515   PMID:7590255   PMID:7750631   PMID:7779685   PMID:8106170   PMID:8575323   PMID:8614804  
PMID:8620844   PMID:8660860   PMID:8674109   PMID:8787740   PMID:8792611   PMID:8898214   PMID:8900279   PMID:8909126   PMID:8978061   PMID:8978698   PMID:9019247   PMID:9097018  
PMID:9152009   PMID:9342041   PMID:9342042   PMID:9363887   PMID:9374397   PMID:9389660   PMID:9391088   PMID:9409668   PMID:9425131   PMID:9428414   PMID:9521905   PMID:9580668  
PMID:9603738   PMID:9631179   PMID:9659925   PMID:9671585   PMID:9694798   PMID:9729491   PMID:9733096   PMID:9733575   PMID:9834182   PMID:9843211   PMID:9847249   PMID:10021340  
PMID:10021368   PMID:10049363   PMID:10075839   PMID:10075849   PMID:10199963   PMID:10210434   PMID:10211882   PMID:10319820   PMID:10349636   PMID:10470645   PMID:10471509   PMID:10534614  
PMID:10534616   PMID:10652274   PMID:10694418   PMID:10753507   PMID:10804187   PMID:10835630   PMID:10969736   PMID:11042159   PMID:11076861   PMID:11101844   PMID:11101846   PMID:11118883  
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Genomics

Comparative Map Data
Hoxd13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39274,498,569 - 74,501,947 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl274,498,654 - 74,501,943 (+)EnsemblGRCm39 Ensembl
GRCm38274,668,225 - 74,671,603 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl274,668,310 - 74,671,599 (+)EnsemblGRCm38mm10GRCm38
MGSCv37274,506,367 - 74,509,655 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36274,469,149 - 74,470,975 (+)NCBIMGSCv36mm8
Celera276,338,416 - 76,341,706 (+)NCBICelera
Cytogenetic Map2C3NCBI
cM Map244.13NCBI
HOXD13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382176,087,487 - 176,095,944 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2176,092,721 - 176,095,944 (+)EnsemblGRCh38hg38GRCh38
GRCh372176,957,449 - 176,960,672 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362176,665,778 - 176,668,912 (+)NCBINCBI36Build 36hg18NCBI36
Build 342176,783,038 - 176,785,307NCBI
Celera2170,566,680 - 170,569,816 (+)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2168,835,017 - 168,838,150 (+)NCBIHuRef
CHM1_12176,963,384 - 176,966,518 (+)NCBICHM1_1
T2T-CHM13v2.02176,580,842 - 176,584,065 (+)NCBIT2T-CHM13v2.0
Hoxd13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8379,978,077 - 79,981,393 (+)NCBIGRCr8
mRatBN7.2359,570,647 - 59,573,963 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl359,570,646 - 59,573,963 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx362,957,898 - 62,961,202 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0371,541,543 - 71,544,847 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0369,306,624 - 69,309,926 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0361,590,376 - 61,593,692 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl361,590,376 - 61,593,692 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0368,056,713 - 68,060,029 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4357,283,682 - 57,286,998 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1357,180,052 - 57,181,906 (+)NCBI
Celera359,093,007 - 59,096,323 (+)NCBICelera
Cytogenetic Map3q23NCBI
Hoxd13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540320,568,314 - 20,575,579 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540320,568,314 - 20,575,579 (-)NCBIChiLan1.0ChiLan1.0
HOXD13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21378,760,254 - 78,763,474 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B78,775,230 - 78,778,450 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B63,372,517 - 63,375,731 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B181,081,518 - 181,085,295 (+)NCBIpanpan1.1PanPan1.1panPan2
HOXD13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13619,901,184 - 19,903,837 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3619,910,345 - 19,913,770 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03620,041,503 - 20,044,951 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3620,041,322 - 20,044,660 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13620,115,748 - 20,119,177 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03620,116,491 - 20,119,912 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03620,228,239 - 20,231,674 (+)NCBIUU_Cfam_GSD_1.0
Hoxd13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303137,025,943 - 137,028,811 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365095,579,843 - 5,581,651 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365095,579,846 - 5,581,651 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOXD13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1581,893,972 - 81,896,944 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11581,893,997 - 81,897,965 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21591,361,348 - 91,364,513 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HOXD13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11061,662,670 - 61,670,955 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1061,667,880 - 61,669,743 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040137,939,510 - 137,942,856 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hoxd13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478713,233,932 - 13,238,503 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478713,233,932 - 13,237,210 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hoxd13
93 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:464
Count of miRNA genes:330
Interacting mature miRNAs:371
Transcripts:ENSMUST00000001872
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13464141Hbbcq3_mhemoglobin concentration QTL 3 (mouse)25244801986448136Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
1301402Ap2q_malcohol preference 2 QTL (mouse)Not determined24352061277520756Mouse
1300761Lgth1_mbody length 1 (mouse)Not determined25170327685703425Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1301405Etohr_methanol response acute (mouse)Not determined26300595497006113Mouse
1301660Iba1_minduction of brown adipocytes 1 (mouse)Not determined267647887101648142Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1300875Taste1_mtaste-saccharin preference 1 (mouse)Not determined25092317584923278Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
1300662Etohila_methanol induced locomotor activity (mouse)Not determined26300595497006113Mouse
1300788Cia2_mcollagen induced arthritis QTL 2 (mouse)Not determined24352061277520756Mouse
10053681Lith24_mlithogenic gene 24 (mouse)Not determined26300595497006113Mouse
1301048Actre2_mactivity response to ethanol 2 (mouse)Not determined26300595497006113Mouse
1300671Cia4_mcollagen induced arthritis QTL 4 (mouse)Not determined24352061277520756Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
1301948Elsgp3_melevated serum gp70 3 (mouse)Not determined268724269102724407Mouse
1301411Pitm1_mprion incubation time 1 (mouse)Not determined24352061277520756Mouse
4141069Pbwg1.5_mpostnatal body weight growth 1.5 (mouse)Not determined4352061277520756Mouse
1558820Moo1_mmodifier of Odc1 (mouse)Not determined174826974682269934Mouse
12738429Lfibq18_mliver fibrosis QTL 18 (mouse)25791999191919991Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1300568Hdl1_mhigh density lipoprotein (HDL) level 1 (mouse)Not determined24826974682269934Mouse
1301059Hrtfm1_mheart failure modifier 1 (mouse)Not determined26759194074964933Mouse
1301703Bomd3_mbone mineral density 3 (mouse)Not determined26300595497006113Mouse
1301747Eae21_mexperimental allergic encephalomyelitis 21 (mouse)Not determined24826974682269934Mouse
1301235Alcw4_malcohol withdrawal 4 (mouse)Not determined24826974682269934Mouse
4141406Alpq2_malcohol preference QTL 2 (mouse)Not determined25752411791524288Mouse
10755526Lymph1_mlymphocyte differential 1 (mouse)25081931484819314Mouse
13463471Hctq6_mhematocrit QTL 6 (mouse)25244801986448136Mouse
1301873Hsl1_mhyperoxia susceptibility locus 1 (mouse)Not determined26357015497570301Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
10755532Lymph5_mlymphocyte differential 5 (mouse)24419901778199017Mouse
1301882Etohc2_methanol consumption 2 (mouse)Not determined268724269102724407Mouse
11532740Pbwg1.10_mpostnatal body weight growth 1.10 (mouse)24813241282132495Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
13463482Mchq17_mmean corpuscular hemoglobin QTL 17 (mouse)267647887101648142Mouse
1301480Pbwg1_mpostnatal body weight growth 1 (mouse)Not determined24182071975820843Mouse
10044002Hdl7_mHDL level 7 (mouse)Not determined26300595497006113Mouse

Markers in Region
Hoxd13  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37274,506,438 - 74,506,599UniSTSGRCm37
MGSCv37274,506,819 - 74,508,082UniSTSGRCm37
MGSCv37274,507,954 - 74,508,187UniSTSGRCm37
Celera276,338,487 - 76,338,648UniSTS
Celera276,340,005 - 76,340,238UniSTS
Celera276,338,868 - 76,340,133UniSTS
Cytogenetic Map2C3UniSTS
cM Map245.0UniSTS
cM Map245.0UniSTS
Hoxd13  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38274,668,762 - 74,670,025UniSTSGRCm38
MGSCv37274,506,819 - 74,508,082UniSTSGRCm37
Celera276,338,868 - 76,340,133UniSTS
Cytogenetic Map2C3UniSTS
cM Map245.0UniSTS
Hoxd13  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38274,668,381 - 74,668,542UniSTSGRCm38
MGSCv37274,506,438 - 74,506,599UniSTSGRCm37
Celera276,338,487 - 76,338,648UniSTS
Cytogenetic Map2C3UniSTS
cM Map245.0UniSTS
Hoxd13  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38274,669,897 - 74,670,130UniSTSGRCm38
MGSCv37274,507,954 - 74,508,187UniSTSGRCm37
Celera276,340,005 - 76,340,238UniSTS
Cytogenetic Map2C3UniSTS
Hoxd13  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2C3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000001872   ⟹   ENSMUSP00000001872
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl274,498,654 - 74,501,943 (+)Ensembl
GRCm38.p6 Ensembl274,668,310 - 74,671,599 (+)Ensembl
RefSeq Acc Id: NM_008275   ⟹   NP_032301
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39274,498,569 - 74,501,947 (+)NCBI
GRCm38274,668,225 - 74,671,603 (+)NCBI
MGSCv37274,506,367 - 74,509,655 (+)RGD
Celera276,338,416 - 76,341,707 (+)NCBI
cM Map2 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_032301 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB21366 (Get FASTA)   NCBI Sequence Viewer  
  CAA67675 (Get FASTA)   NCBI Sequence Viewer  
  EDL27167 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000001872
  ENSMUSP00000001872.5
GenBank Protein P70217 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_032301   ⟸   NM_008275
- UniProtKB: Q2VPB1 (UniProtKB/Swiss-Prot),   Q2VPB0 (UniProtKB/Swiss-Prot),   A2ASM5 (UniProtKB/Swiss-Prot),   Q64177 (UniProtKB/Swiss-Prot),   P70217 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000001872   ⟸   ENSMUST00000001872

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70217-F1-model_v2 AlphaFold P70217 1-339 view protein structure

Promoters
RGD ID:6831589
Promoter ID:MM_KWN:29747
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000032142
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36274,505,491 - 74,506,892 (+)MPROMDB
RGD ID:6877648
Promoter ID:EPDNEW_M2275
Type:multiple initiation site
Name:Hoxd13_1
Description:Mus musculus homeobox D13 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38274,668,397 - 74,668,457EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96205 AgrOrtholog
Ensembl Genes ENSMUSG00000001819 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000001872 ENTREZGENE
  ENSMUST00000001872.5 UniProtKB/Swiss-Prot
Gene3D-CATH Homeodomain-like UniProtKB/Swiss-Prot
InterPro AP_axis_regulatory_Homeobox UniProtKB/Swiss-Prot
  Homeobox-like_sf UniProtKB/Swiss-Prot
  Homeobox_CS UniProtKB/Swiss-Prot
  Homeobox_dom UniProtKB/Swiss-Prot
  HoxA13_N UniProtKB/Swiss-Prot
KEGG Report mmu:15433 UniProtKB/Swiss-Prot
MGD MGI:96205 ENTREZGENE
NCBI Gene 15433 ENTREZGENE
PANTHER HOMEOBOX PROTEIN HOX-D13 UniProtKB/Swiss-Prot
  SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN UniProtKB/Swiss-Prot
Pfam Homeodomain UniProtKB/Swiss-Prot
  HoxA13_N UniProtKB/Swiss-Prot
PhenoGen Hoxd13 PhenoGen
PROSITE HOMEOBOX_1 UniProtKB/Swiss-Prot
  HOMEOBOX_2 UniProtKB/Swiss-Prot
SMART HOX UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot
UniProt A2ASM5 ENTREZGENE
  HXD13_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q2VPB0 ENTREZGENE
  Q2VPB1 ENTREZGENE
  Q64177 ENTREZGENE
UniProt Secondary A2ASM5 UniProtKB/Swiss-Prot
  Q2VPB0 UniProtKB/Swiss-Prot
  Q2VPB1 UniProtKB/Swiss-Prot
  Q64177 UniProtKB/Swiss-Prot