Gtf2h1 (general transcription factor II H, polypeptide 1) - Rat Genome Database

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Gene: Gtf2h1 (general transcription factor II H, polypeptide 1) Mus musculus
Analyze
Symbol: Gtf2h1
Name: general transcription factor II H, polypeptide 1
RGD ID: 1317879
MGI Page MGI
Description: Predicted to enable chromatin binding activity and nuclear thyroid hormone receptor binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in nucleus. Is expressed in central nervous system and testis. Orthologous to human GTF2H1 (general transcription factor IIH subunit 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 62kD; 62kDa; AW743425; AW822074; basic transcription factor 2 62 kDa subunit; BTF2 p62; BTF2-p62; C77871; general transcription factor IIH subunit 1; general transcription factor IIH, polypeptide 1 (62kD subunit); p6; p62; TFIIH basal transcription factor complex p62 subunit
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm4105  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39746,445,518 - 46,473,224 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl746,445,527 - 46,473,224 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38746,796,094 - 46,823,800 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl746,796,103 - 46,823,800 (+)Ensemblmm10GRCm38
MGSCv37754,051,464 - 54,079,170 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36746,664,145 - 46,691,839 (+)NCBIMGSCv36mm8
Celera742,274,479 - 42,302,829 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map730.58NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4-amino-2,6-dinitrotoluene  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aluminium sulfate (anhydrous)  (ISO)
Aroclor 1254  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (ISO)
Bisphenol A diglycidyl ether  (EXP)
bisphenol AF  (EXP)
cadmium dichloride  (ISO)
chromium(6+)  (EXP)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
cypermethrin  (EXP)
decabromodiphenyl ether  (ISO)
dicrotophos  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP)
fenthion  (EXP)
finasteride  (ISO)
flutamide  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
hydrogen peroxide  (ISO)
L-ascorbic acid  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methidathion  (EXP)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nimesulide  (ISO)
nitrates  (EXP)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
pentachlorophenol  (EXP)
phenylmercury acetate  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
zidovudine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. TFIIH: when transcription met DNA repair. Compe E and Egly JM, Nat Rev Mol Cell Biol. 2012 May 10;13(6):343-54. doi: 10.1038/nrm3350.
2. A history of TFIIH: two decades of molecular biology on a pivotal transcription/repair factor. Egly JM and Coin F, DNA Repair (Amst). 2011 Jul 15;10(7):714-21. doi: 10.1016/j.dnarep.2011.04.021. Epub 2011 May 17.
3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
4. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6. Zhang Q, etal., Nat Genet 2003 Feb;33(2):145-53.
Additional References at PubMed
PMID:9630526   PMID:10349636   PMID:10777215   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12509240   PMID:12520002   PMID:12815074   PMID:14610273   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:16517408   PMID:17699685   PMID:18287559   PMID:18799693   PMID:20059953   PMID:20154642   PMID:20211142   PMID:20439489   PMID:20974803   PMID:21267068   PMID:21659648  
PMID:21677750   PMID:21873635   PMID:22323595   PMID:23872361   PMID:24173291   PMID:28190767   PMID:35993019  


Genomics

Comparative Map Data
Gtf2h1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39746,445,518 - 46,473,224 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl746,445,527 - 46,473,224 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38746,796,094 - 46,823,800 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl746,796,103 - 46,823,800 (+)Ensemblmm10GRCm38
MGSCv37754,051,464 - 54,079,170 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36746,664,145 - 46,691,839 (+)NCBIMGSCv36mm8
Celera742,274,479 - 42,302,829 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map730.58NCBI
GTF2H1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381118,322,567 - 18,367,045 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1118,322,295 - 18,367,045 (+)Ensemblhg38GRCh38
GRCh371118,344,114 - 18,388,592 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361118,300,719 - 18,345,153 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341118,300,718 - 18,345,152NCBI
Celera1118,476,032 - 18,520,801 (+)NCBICelera
Cytogenetic Map11p15.1NCBI
HuRef1118,026,329 - 18,071,105 (+)NCBIHuRef
CHM1_11118,343,304 - 18,388,093 (+)NCBICHM1_1
T2T-CHM13v2.01118,418,103 - 18,462,582 (+)NCBIT2T-CHM13v2.0
Gtf2h1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81106,457,692 - 106,485,729 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1106,457,394 - 106,485,727 (+)EnsemblGRCr8
mRatBN7.2197,321,417 - 97,349,455 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl197,321,394 - 97,349,455 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1102,713,646 - 102,741,801 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01111,185,630 - 111,213,785 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01104,469,761 - 104,497,796 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01102,849,618 - 102,877,939 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1102,849,889 - 102,877,944 (+)Ensemblrn6Rnor6.0
Rnor_5.01103,923,681 - 103,951,995 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4197,352,251 - 97,380,298 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera191,568,224 - 91,596,262 (+)NCBICelera
RGSC_v3.1197,430,363 - 97,458,409 (+)NCBI
Cytogenetic Map1q22NCBI
Gtf2h1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541433,028,701 - 33,063,233 (+)Ensembl
ChiLan1.0NW_00495541433,028,701 - 33,063,233 (+)NCBIChiLan1.0ChiLan1.0
GTF2H1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2920,636,598 - 20,681,276 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11120,596,985 - 20,641,633 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01118,357,594 - 18,402,268 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11118,042,822 - 18,086,898 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1118,042,824 - 18,086,898 (+)EnsemblpanPan2panpan1.1
GTF2H1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12140,770,661 - 40,807,329 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2140,770,983 - 40,806,556 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2140,250,242 - 40,286,596 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02141,894,288 - 41,930,625 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2141,894,288 - 41,930,623 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12140,886,602 - 40,922,934 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02141,075,253 - 41,111,663 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02141,452,829 - 41,489,189 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gtf2h1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494744,869,445 - 44,906,096 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936528903,322 - 940,313 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936528903,429 - 940,308 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GTF2H1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl240,857,723 - 40,900,624 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1240,857,720 - 40,900,591 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2243,921,524 - 43,964,052 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GTF2H1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1146,573,907 - 46,620,443 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl146,573,393 - 46,609,261 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038143,946,538 - 143,998,018 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gtf2h1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247669,808,170 - 9,848,173 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247669,807,973 - 9,848,167 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Gtf2h1
1585 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:861
Count of miRNA genes:503
Interacting mature miRNAs:565
Transcripts:ENSMUST00000006774, ENSMUST00000107644, ENSMUST00000128420, ENSMUST00000144708, ENSMUST00000165031
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
38501071Stsl6_mSalmonella typhimurium susceptibility locus 6 (mouse)73419942551149748Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
39128210Lwq19_mliver weight QTL 19 (mouse)73349772758148965Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
1357469Kidq5_mkidney weight QTL 5 (mouse)Not determined73349772758148965Mouse
4142003W3q10_mweight 3 weeks QTL 10 (mouse)Not determined3349772758148965Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse
1559000Ossc1_mosteosarcoma susceptibility 1 (mouse)Not determined73405302568053223Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
1357634Splq7_mspleen weight QTL 7 (mouse)Not determined73349772758148965Mouse
4141929Chlq18_mcirculating hormone level QTL 18 (mouse)Not determined74114882075148965Mouse
1300996Aorls2_maortic lesion size 2 (mouse)Not determined73239453266394681Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
1300878Skts1_mskin tumor susceptibility 1 (mouse)Not determined73789138671891582Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
1301175Ap7q_malcohol preference 7 QTL (mouse)Not determined73171484565715077Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
12880417V125Dq5_mvitamin D active form serum level QTL 5 (mouse)74524974879249748Mouse
10402488Dipa2_mdrug induced psychomotor activation 2 (mouse)Not determined73842154872421684Mouse
4142102Tailq5_mtail length QTL 5 (mouse)Not determined3349772758148965Mouse
4141909W10q18_mweight 10 weeks QTL 18 (mouse)Not determined3349772758148965Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1357883Epfq5_mepididymal fat pad weight QTL 5 (mouse)Not determined73349772758148965Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
10045622Heal20_mwound healing/regeneration 20 (mouse)Not determined73431688768317043Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
4142218W6q17_mweight 6 weeks QTL 17 (mouse)Not determined3349772758148965Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse
25314301Vmm3_mvariable multisystem mineralization 3, lung (mouse)73729942572049748Mouse

Markers in Region
AW822074  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38746,815,332 - 46,815,519UniSTSGRCm38
MGSCv37754,070,702 - 54,070,889UniSTSGRCm37
Celera747,862,607 - 47,862,794UniSTS
Celera742,293,722 - 42,293,909UniSTS
Cytogenetic Map7B4UniSTS
Whitehead/MRC_RH7584.1UniSTS
UniSTS:235670  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38746,796,729 - 46,797,098UniSTSGRCm38
MGSCv37754,052,099 - 54,052,468UniSTSGRCm37
Celera742,275,114 - 42,275,483UniSTS
Cytogenetic Map7B4UniSTS
cM Map725.0UniSTS
RH126259  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38746,822,933 - 46,823,182UniSTSGRCm38
MGSCv37754,078,303 - 54,078,552UniSTSGRCm37
Celera747,591,403 - 47,591,653UniSTS
Celera742,301,962 - 42,302,211UniSTS
Cytogenetic Map7B4UniSTS
Whitehead/MRC_RH7582.57UniSTS
Rap1a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38746,820,265 - 46,821,010UniSTSGRCm38
Celera742,299,294 - 42,300,039UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map3F2.2UniSTS
cM Map346.45UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000006774   ⟹   ENSMUSP00000006774
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl746,445,527 - 46,473,224 (+)Ensembl
GRCm38.p6 Ensembl746,796,103 - 46,823,800 (+)Ensembl
Ensembl Acc Id: ENSMUST00000107644   ⟹   ENSMUSP00000103271
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl746,446,095 - 46,472,699 (+)Ensembl
GRCm38.p6 Ensembl746,796,671 - 46,823,275 (+)Ensembl
Ensembl Acc Id: ENSMUST00000128420   ⟹   ENSMUSP00000120008
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl746,451,111 - 46,472,333 (+)Ensembl
GRCm38.p6 Ensembl746,801,687 - 46,822,909 (+)Ensembl
Ensembl Acc Id: ENSMUST00000144708
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl746,457,876 - 46,464,842 (+)Ensembl
GRCm38.p6 Ensembl746,808,452 - 46,815,418 (+)Ensembl
Ensembl Acc Id: ENSMUST00000165031   ⟹   ENSMUSP00000129337
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl746,445,538 - 46,454,451 (+)Ensembl
GRCm38.p6 Ensembl746,796,114 - 46,805,027 (+)Ensembl
RefSeq Acc Id: NM_001291075   ⟹   NP_001278004
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39746,446,095 - 46,473,224 (+)NCBI
GRCm38746,796,671 - 46,823,800 (+)NCBI
Celera742,274,479 - 42,302,829 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001360075   ⟹   NP_001347004
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39746,446,095 - 46,473,224 (+)NCBI
GRCm38746,796,671 - 46,823,800 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001360076   ⟹   NP_001347005
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39746,445,518 - 46,473,224 (+)NCBI
GRCm38746,796,094 - 46,823,800 (+)NCBI
Sequence:
RefSeq Acc Id: NM_008186   ⟹   NP_032212
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39746,445,518 - 46,473,224 (+)NCBI
GRCm38746,796,094 - 46,823,800 (+)NCBI
MGSCv37754,051,464 - 54,079,170 (+)RGD
Celera742,274,479 - 42,302,829 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032212   ⟸   NM_008186
- Peptide Label: isoform 2
- UniProtKB: O35637 (UniProtKB/Swiss-Prot),   Q9DBA9 (UniProtKB/Swiss-Prot),   G3X8R4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278004   ⟸   NM_001291075
- Peptide Label: isoform 1
- UniProtKB: O35637 (UniProtKB/Swiss-Prot),   Q9DBA9 (UniProtKB/Swiss-Prot),   E9QKD9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001347005   ⟸   NM_001360076
- Peptide Label: isoform 1
- UniProtKB: Q9DBA9 (UniProtKB/Swiss-Prot),   O35637 (UniProtKB/Swiss-Prot),   E9QKD9 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001347004   ⟸   NM_001360075
- Peptide Label: isoform 3
- UniProtKB: Q9DBA9 (UniProtKB/Swiss-Prot),   O35637 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSMUSP00000006774   ⟸   ENSMUST00000006774
Ensembl Acc Id: ENSMUSP00000103271   ⟸   ENSMUST00000107644
Ensembl Acc Id: ENSMUSP00000129337   ⟸   ENSMUST00000165031
Ensembl Acc Id: ENSMUSP00000120008   ⟸   ENSMUST00000128420
Protein Domains
BSD   TFIIH p62 subunit N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9DBA9-F1-model_v2 AlphaFold Q9DBA9 1-547 view protein structure

Promoters
RGD ID:8664145
Promoter ID:EPDNEW_M10103
Type:initiation region
Name:Gtf2h1_1
Description:Mus musculus general transcription factor II H, polypeptide 1, transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38746,796,114 - 46,796,174EPDNEW
RGD ID:6841311
Promoter ID:MM_KWN:50516
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000051883,   ENSMUST00000107649,   ENSMUST00000107654,   NM_001005247_HPS5,   NM_001005248,   NM_001167864,   NM_008186,   OTTMUST00000059780,   OTTMUST00000059783,   OTTMUST00000059784,   OTTMUST00000059787,   OTTMUST00000059788,   OTTMUST00000059811,   UC009GZC.1,   UC009GZD.1,   UC009GZE.1,   UC009GZF.1,   UC009GZJ.1,   UC009GZL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36754,050,981 - 54,051,732 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1277216 AgrOrtholog
Ensembl Genes ENSMUSG00000006599 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000006774 ENTREZGENE
  ENSMUST00000107644 ENTREZGENE
Gene3D-CATH 1.10.3970.10 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
  6.10.140.1200 UniProtKB/Swiss-Prot
InterPro BSD_dom UniProtKB/Swiss-Prot
  BSD_dom_sf UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  Tfb1/GTF2H1 UniProtKB/Swiss-Prot
  TFIIH_BTF_p62_N UniProtKB/Swiss-Prot
KEGG Report mmu:14884 UniProtKB/Swiss-Prot
MGD MGI:1277216 ENTREZGENE
NCBI Gene 14884 ENTREZGENE
PANTHER PTHR12856 UniProtKB/Swiss-Prot
Pfam BSD UniProtKB/Swiss-Prot
  PH_TFIIH UniProtKB/Swiss-Prot
PhenoGen Gtf2h1 PhenoGen
PROSITE BSD UniProtKB/Swiss-Prot
SMART BSD UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  SSF140383 UniProtKB/Swiss-Prot
UniProt D6RJL7_MOUSE UniProtKB/TrEMBL
  E9PWY2_MOUSE UniProtKB/TrEMBL
  E9QKD9 ENTREZGENE, UniProtKB/TrEMBL
  G3X8R4 ENTREZGENE, UniProtKB/TrEMBL
  O35637 ENTREZGENE
  Q7TPY0_MOUSE UniProtKB/TrEMBL
  Q9DBA9 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary O35637 UniProtKB/Swiss-Prot