Mrpl30 (mitochondrial ribosomal protein L30) - Rat Genome Database

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Gene: Mrpl30 (mitochondrial ribosomal protein L30) Mus musculus
Analyze
Symbol: Mrpl30
Name: mitochondrial ribosomal protein L30
RGD ID: 1317835
MGI Page MGI
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL30 (mitochondrial ribosomal protein L30).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2310001L22Rik; 39S ribosomal protein L30, mitochondrial; L30mt; large ribosomal subunit protein uL30m; MRP-; MRP-L28; MRP-L30; ribosomal protein, mitochondrial, L28; Rpm; Rpml28
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm18709   Gm6238   Gm6746  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39137,929,558 - 37,937,419 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl137,929,558 - 37,937,616 (+)EnsemblGRCm39 Ensembl
GRCm38137,890,477 - 37,898,338 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl137,890,477 - 37,898,535 (+)EnsemblGRCm38mm10GRCm38
MGSCv37137,947,398 - 37,955,178 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36137,835,099 - 37,842,879 (+)NCBIMGSCv36mm8
Celera137,671,472 - 37,679,443 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map116.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9857009   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:15489334   PMID:16141072   PMID:16141073   PMID:18614015  
PMID:18799693   PMID:21677750   PMID:21873635   PMID:25278503   PMID:27023846   PMID:29222160   PMID:32325033   PMID:32987154  


Genomics

Comparative Map Data
Mrpl30
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39137,929,558 - 37,937,419 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl137,929,558 - 37,937,616 (+)EnsemblGRCm39 Ensembl
GRCm38137,890,477 - 37,898,338 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl137,890,477 - 37,898,535 (+)EnsemblGRCm38mm10GRCm38
MGSCv37137,947,398 - 37,955,178 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36137,835,099 - 37,842,879 (+)NCBIMGSCv36mm8
Celera137,671,472 - 37,679,443 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map116.17NCBI
MRPL30
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38299,181,184 - 99,199,561 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl299,181,152 - 99,199,561 (+)EnsemblGRCh38hg38GRCh38
GRCh37299,797,647 - 99,816,024 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36299,164,010 - 99,180,521 (+)NCBINCBI36Build 36hg18NCBI36
Build 34299,256,095 - 99,272,414NCBI
Celera294,002,173 - 94,018,689 (+)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef293,563,315 - 93,581,802 (+)NCBIHuRef
CHM1_1299,802,440 - 99,820,922 (+)NCBICHM1_1
T2T-CHM13v2.0299,640,062 - 99,658,443 (+)NCBIT2T-CHM13v2.0
Mrpl30
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8947,621,226 - 47,631,986 (+)NCBIGRCr8
mRatBN7.2940,125,352 - 40,136,189 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl940,125,430 - 40,137,257 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx948,621,247 - 48,632,004 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0953,744,002 - 53,754,759 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0952,026,129 - 52,036,888 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0944,483,809 - 44,496,116 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl944,483,875 - 44,571,331 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0944,181,199 - 44,193,496 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4936,839,342 - 36,850,101 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1936,840,769 - 36,851,515 (+)NCBI
Celera937,879,660 - 37,890,419 (+)NCBICelera
Cytogenetic Map9q21NCBI
Mrpl30
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554705,509,216 - 5,522,552 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554705,509,517 - 5,519,633 (+)NCBIChiLan1.0ChiLan1.0
MRPL30
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21229,206,579 - 29,248,923 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A29,216,713 - 29,251,683 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A100,099,758 - 100,116,240 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A100,111,515 - 100,129,797 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A100,111,515 - 100,127,864 (+)Ensemblpanpan1.1panPan2
MRPL30
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11043,494,658 - 43,513,241 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1043,418,142 - 43,436,770 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01044,366,676 - 44,385,400 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1044,364,571 - 44,385,355 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11044,076,874 - 44,095,427 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01044,360,325 - 44,378,962 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01044,544,720 - 44,563,427 (-)NCBIUU_Cfam_GSD_1.0
Mrpl30
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629284,957,894 - 84,958,741 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366611,610,765 - 1,619,598 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRPL30
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl355,032,996 - 55,076,388 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1355,041,645 - 55,054,439 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2357,676,960 - 57,684,579 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MRPL30
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1142,902,811 - 2,921,394 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl142,902,894 - 2,917,668 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041170,506,485 - 170,524,523 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrpl30
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247494,190,173 - 4,195,363 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247494,186,036 - 4,195,857 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mrpl30
421 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:602
Count of miRNA genes:453
Interacting mature miRNAs:499
Transcripts:ENSMUST00000027256, ENSMUST00000160082, ENSMUST00000161694, ENSMUST00000162513
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1301011Cplaq4_mcircadian period of locomotor activity 4 (mouse)Not determined1967344243673601Mouse
1357524W6q14_mweight 6 weeks QTL 14 (mouse)Not determined13476013873976915Mouse
1301073Orch5_mautoimmune orchitis resistance 5 (mouse)Not determined11906535153065454Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
1357651Lgq5_mlate growth QTL 5 (mouse)Not determined13476013873976915Mouse
11100001Col4a1m1_mcollagen, type IV, alpha 1 modifier 1 (mouse)12555019162946882Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
1301240Sluc15_msusceptibility to lung cancer 15 (mouse)Not determined11906535153065454Mouse
1357759W3q12_mweight 3 weeks QTL 12 (mouse)Not determined13476013873976915Mouse
1301471Obq2_mobesity QTL 2 (mouse)Not determined1394162037941887Mouse
14700685Civq2_mcerebral infarct volume QTL 2 (mouse)11134048245340482Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1301756Pgia1_mproteoglycan induced arthritis 1 (mouse)Not determined11906535153065454Mouse
12880407V125Dq2_mvitamin D active form serum level QTL 2 (mouse)11933908153339081Mouse
1357824Estoq4_membryo survival total QTL 4 (mouse)Not determined13476013873976915Mouse
1357506W10q6_mweight 10 weeks QTL 6 (mouse)Not determined13476013873976915Mouse
1357475w3q13_mweight 3 weeks QTL 13 (mouse)Not determined12310959173976915Mouse
39128207Lwq16_mliver weight QTL 16 (mouse)13476013873976915Mouse
10043970Obq23_mobesity QTL 23 (mouse)Not determined1501266539012665Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
12880409V125Dq1_mvitamin D active form serum level QTL 1 (mouse)12603916060039160Mouse
4142433Hbnr1_mHeligmosomoides bakeri nematode resistance 1 (mouse)Not determined2555019158273271Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000027256   ⟹   ENSMUSP00000027256
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl137,929,558 - 37,937,616 (+)Ensembl
GRCm38.p6 Ensembl137,890,477 - 37,898,535 (+)Ensembl
Ensembl Acc Id: ENSMUST00000160082   ⟹   ENSMUSP00000141883
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl137,929,624 - 37,933,065 (+)Ensembl
GRCm38.p6 Ensembl137,890,543 - 37,893,984 (+)Ensembl
Ensembl Acc Id: ENSMUST00000161694
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl137,929,614 - 37,932,327 (+)Ensembl
GRCm38.p6 Ensembl137,890,533 - 37,893,246 (+)Ensembl
Ensembl Acc Id: ENSMUST00000162513
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl137,936,337 - 37,937,206 (+)Ensembl
GRCm38.p6 Ensembl137,897,256 - 37,898,125 (+)Ensembl
Ensembl Acc Id: ENSMUST00000193673   ⟹   ENSMUSP00000141654
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl137,929,613 - 37,937,445 (+)Ensembl
GRCm38.p6 Ensembl137,890,532 - 37,898,364 (+)Ensembl
Ensembl Acc Id: ENSMUST00000194857   ⟹   ENSMUSP00000142168
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl137,932,014 - 37,937,246 (+)Ensembl
GRCm38.p6 Ensembl137,892,933 - 37,898,165 (+)Ensembl
Ensembl Acc Id: ENSMUST00000195373   ⟹   ENSMUSP00000141693
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl137,933,016 - 37,937,419 (+)Ensembl
GRCm38.p6 Ensembl137,893,935 - 37,898,338 (+)Ensembl
RefSeq Acc Id: NM_001356482   ⟹   NP_001343411
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39137,929,558 - 37,937,419 (+)NCBI
GRCm38137,890,477 - 37,898,338 (+)NCBI
Sequence:
RefSeq Acc Id: NM_027098   ⟹   NP_081374
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39137,929,558 - 37,937,419 (+)NCBI
GRCm38137,890,477 - 37,898,338 (+)NCBI
MGSCv37137,947,398 - 37,955,178 (+)RGD
Celera137,671,472 - 37,679,443 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011238417   ⟹   XP_011236719
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39137,929,634 - 37,937,419 (+)NCBI
GRCm38137,890,553 - 37,898,338 (+)NCBI
Sequence:
RefSeq Acc Id: NP_081374   ⟸   NM_027098
- Peptide Label: precursor
- UniProtKB: Q9D7N6 (UniProtKB/Swiss-Prot),   Q99KJ7 (UniProtKB/Swiss-Prot),   A0A0A6YXW4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011236719   ⟸   XM_011238417
- Peptide Label: isoform X1
- UniProtKB: Q9D7N6 (UniProtKB/Swiss-Prot),   Q99KJ7 (UniProtKB/Swiss-Prot),   A0A0A6YXW4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001343411   ⟸   NM_001356482
- Peptide Label: precursor
- UniProtKB: Q9D7N6 (UniProtKB/Swiss-Prot),   Q99KJ7 (UniProtKB/Swiss-Prot),   A0A0A6YXW4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000027256   ⟸   ENSMUST00000027256
Ensembl Acc Id: ENSMUSP00000141883   ⟸   ENSMUST00000160082
Ensembl Acc Id: ENSMUSP00000141654   ⟸   ENSMUST00000193673
Ensembl Acc Id: ENSMUSP00000141693   ⟸   ENSMUST00000195373
Ensembl Acc Id: ENSMUSP00000142168   ⟸   ENSMUST00000194857
Protein Domains
Large ribosomal subunit protein uL30-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D7N6-F1-model_v2 AlphaFold Q9D7N6 1-160 view protein structure

Promoters
RGD ID:6873498
Promoter ID:EPDNEW_M200
Type:initiation region
Name:Mrpl30_1
Description:Mus musculus mitochondrial ribosomal protein L30 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38137,890,541 - 37,890,601EPDNEW
RGD ID:6818087
Promoter ID:MM_KWN:496
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000065720,   OTTMUST00000065721,   OTTMUST00000065724,   OTTMUST00000065791,   OTTMUST00000065792
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36137,946,341 - 37,947,467 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1333820 AgrOrtholog
Ensembl Genes ENSMUSG00000026087 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000027256 ENTREZGENE
  ENSMUST00000027256.12 UniProtKB/Swiss-Prot
  ENSMUST00000193673 ENTREZGENE
  ENSMUST00000193673.6 UniProtKB/Swiss-Prot
  ENSMUST00000195373.2 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1390.20 UniProtKB/Swiss-Prot
InterPro L30_ferredoxin-like_sf UniProtKB/Swiss-Prot
  Ribosomal_L30_bac-type UniProtKB/Swiss-Prot
  Ribosomal_L30_ferredoxin-like UniProtKB/Swiss-Prot
KEGG Report mmu:107734 UniProtKB/Swiss-Prot
MGD MGI:1333820 ENTREZGENE
NCBI Gene Mrpl30 ENTREZGENE
PANTHER 39S RIBOSOMAL PROTEIN L30, MITOCHONDRIAL UniProtKB/Swiss-Prot
  PTHR15892 UniProtKB/Swiss-Prot
Pfam Ribosomal_L30 UniProtKB/Swiss-Prot
PhenoGen Mrpl30 PhenoGen
Superfamily-SCOP SSF55129 UniProtKB/Swiss-Prot
UniProt A0A0A6YXW4 ENTREZGENE, UniProtKB/TrEMBL
  Q99KJ7 ENTREZGENE
  Q9D7N6 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q99KJ7 UniProtKB/Swiss-Prot