Fign (fidgetin) - Rat Genome Database

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Gene: Fign (fidgetin) Mus musculus
Analyze
Symbol: Fign
Name: fidgetin
RGD ID: 1317799
MGI Page MGI
Description: Predicted to enable ATP hydrolysis activity and microtubule severing ATPase activity. Acts upstream of or within locomotory behavior. Located in nuclear matrix. Is expressed in central nervous system and heart. Orthologous to human FIGN (fidgetin, microtubule severing factor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fg; Fgn; fi; fidget
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39263,801,852 - 63,928,382 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl263,801,851 - 63,928,382 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38263,971,508 - 64,098,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl263,971,507 - 64,098,038 (-)Ensemblmm10GRCm38
MGSCv37263,815,418 - 63,936,064 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36263,778,670 - 63,898,827 (-)NCBIMGSCv36mm8
Celera265,662,900 - 65,783,578 (-)NCBICelera
Cytogenetic Map2C1.3NCBI
cM Map237.19NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (EXP)
dioxygen  (EXP)
dorsomorphin  (ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
fonofos  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
melphalan  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
pentanal  (ISO)
permethrin  (ISO)
phenobarbital  (EXP)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
quercetin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (EXP)
terbufos  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centrosome  (IEA)
cytoplasm  (IBA,IEA)
cytoskeleton  (IEA)
microtubule  (IEA)
nuclear matrix  (IDA,IEA)
nucleus  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal acetabular fossa morphology  (IEA)
abnormal cell cycle  (IAGP)
abnormal cell cycle checkpoint function  (IAGP)
abnormal cerebellar lobule formation  (IEA)
abnormal craniofacial bone morphology  (IEA)
abnormal locomotor coordination  (IEA)
abnormal mandible morphology  (IEA)
abnormal maternal nurturing  (IEA)
abnormal membranous labyrinth morphology  (IEA)
abnormal otic capsule morphology  (IEA)
abnormal pelvic girdle bone morphology  (IEA)
abnormal pterygoid process morphology  (IEA)
abnormal retina development  (IAGP)
abnormal retina progenitor cell morphology  (IAGP)
abnormal semicircular canal morphology  (IAGP)
absent lacrimal glands  (IEA)
absent lateral semicircular canal  (IEA)
absent mandibular canal  (IEA)
absent mandibular foramen  (IEA)
absent mental foramen  (IEA)
absent semicircular canals  (IAGP)
absent subarcuate fossa  (IEA)
bidirectional circling  (IEA)
cleft secondary palate  (IAGP)
conjunctivitis  (IEA)
cornea opacity  (IEA)
cornea perforation  (IEA)
cornea vascularization  (IEA)
cyanosis  (IAGP)
deafness  (IEA)
decreased body weight  (IEA)
eye inflammation  (IEA)
fused tarsal bones  (IEA)
Harderian gland hypertrophy  (IEA)
head shaking  (IAGP)
hip dislocation  (IEA)
impaired coordination  (IEA)
increased startle reflex  (IEA)
increased susceptibility to age-related hearing loss  (IEA)
Meibomian gland hypertrophy  (IEA)
microphthalmia  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
open neural tube  (IEA)
polydactyly  (IEA)
postnatal growth retardation  (IEA)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
prenatal lethality, complete penetrance  (IEA)
prenatal lethality, incomplete penetrance  (IAGP)
reduced fertility  (IEA)
respiratory distress  (IAGP)
small lens  (IEA)
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:904847   PMID:970345   PMID:1001817   PMID:1018005   PMID:1971250   PMID:4644332   PMID:4837306   PMID:5088022   PMID:10349636   PMID:11017077   PMID:11042159   PMID:11076861  
PMID:11217851   PMID:11256068   PMID:12447396   PMID:12477932   PMID:14073604   PMID:14775691   PMID:14802993   PMID:15489334   PMID:15707573   PMID:16141072   PMID:16141073   PMID:16751186  
PMID:16919269   PMID:18199763   PMID:21267068   PMID:21451961   PMID:21677750   PMID:21873635   PMID:24539707   PMID:25535916   PMID:26344772   PMID:26496610   PMID:28190640   PMID:28302752  
PMID:29475039   PMID:30647150   PMID:31597102   PMID:33468540  


Genomics

Comparative Map Data
Fign
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39263,801,852 - 63,928,382 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl263,801,851 - 63,928,382 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38263,971,508 - 64,098,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl263,971,507 - 64,098,038 (-)Ensemblmm10GRCm38
MGSCv37263,815,418 - 63,936,064 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36263,778,670 - 63,898,827 (-)NCBIMGSCv36mm8
Celera265,662,900 - 65,783,578 (-)NCBICelera
Cytogenetic Map2C1.3NCBI
cM Map237.19NCBI
FIGN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382163,602,611 - 163,736,008 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2163,593,396 - 163,736,012 (-)Ensemblhg38GRCh38
GRCh372164,459,121 - 164,592,518 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362164,172,364 - 164,300,759 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342164,291,556 - 164,293,651NCBI
Celera2158,074,075 - 158,202,502 (-)NCBICelera
Cytogenetic Map2q24.3NCBI
HuRef2156,346,627 - 156,474,914 (-)NCBIHuRef
CHM1_12164,470,008 - 164,598,433 (-)NCBICHM1_1
T2T-CHM13v2.02164,059,859 - 164,193,293 (-)NCBIT2T-CHM13v2.0
Fign
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8369,045,918 - 69,169,148 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl369,045,050 - 69,169,988 (-)EnsemblGRCr8
mRatBN7.2348,637,510 - 48,760,772 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl348,642,496 - 48,760,787 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx351,971,883 - 52,089,709 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0360,555,393 - 60,673,211 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0358,345,891 - 58,463,522 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0349,992,250 - 50,120,601 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl349,992,397 - 50,120,392 (-)Ensemblrn6Rnor6.0
Rnor_5.0356,637,401 - 56,764,164 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4346,006,895 - 46,130,212 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera348,260,684 - 48,378,383 (-)NCBICelera
RGSC_v3.1345,903,265 - 46,026,612 (-)NCBI
Cytogenetic Map3q21NCBI
Fign
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544910,271,014 - 10,393,859 (+)Ensembl
ChiLan1.0NW_00495544910,271,125 - 10,400,631 (+)NCBIChiLan1.0ChiLan1.0
FIGN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21366,279,486 - 66,407,932 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B66,289,122 - 66,600,382 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B50,889,187 - 51,022,435 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B168,259,440 - 168,387,036 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B168,258,315 - 168,385,768 (-)EnsemblpanPan2panpan1.1
FIGN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1368,914,023 - 9,045,240 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl368,920,224 - 8,922,977 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha369,049,767 - 9,190,855 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0369,038,947 - 9,180,410 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl369,039,164 - 9,180,469 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1369,048,565 - 9,189,817 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0369,106,216 - 9,231,397 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0369,220,027 - 9,345,231 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fign
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303126,059,464 - 126,183,759 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646915,434,127 - 15,553,438 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493646915,434,150 - 15,556,167 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FIGN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1570,262,091 - 70,394,095 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11570,255,270 - 70,394,095 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21578,089,130 - 78,245,808 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FIGN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11049,035,120 - 49,453,559 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1049,052,032 - 49,178,962 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040150,341,369 - 150,475,693 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fign
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247321,770,852 - 1,899,842 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247321,770,794 - 1,904,398 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Fign
6047 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:3412
Count of miRNA genes:955
Interacting mature miRNAs:1335
Transcripts:ENSMUST00000102728, ENSMUST00000126042, ENSMUST00000131615, ENSMUST00000153538
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13464141Hbbcq3_mhemoglobin concentration QTL 3 (mouse)25244801986448136Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
1301402Ap2q_malcohol preference 2 QTL (mouse)Not determined24352061277520756Mouse
4142133Pbwg1.6_mpostnatal body weight growth 1.6 (mouse)Not determined3579732469797406Mouse
1300761Lgth1_mbody length 1 (mouse)Not determined25170327685703425Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1301405Etohr_methanol response acute (mouse)Not determined26300595497006113Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1300875Taste1_mtaste-saccharin preference 1 (mouse)Not determined25092317584923278Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
13432174Actres5_mactivity response to ethanol/saline 5 (mouse)25989228769792287Mouse
1300662Etohila_methanol induced locomotor activity (mouse)Not determined26300595497006113Mouse
1300788Cia2_mcollagen induced arthritis QTL 2 (mouse)Not determined24352061277520756Mouse
10053681Lith24_mlithogenic gene 24 (mouse)Not determined26300595497006113Mouse
1301048Actre2_mactivity response to ethanol 2 (mouse)Not determined26300595497006113Mouse
1300671Cia4_mcollagen induced arthritis QTL 4 (mouse)Not determined24352061277520756Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1301411Pitm1_mprion incubation time 1 (mouse)Not determined24352061277520756Mouse
4141069Pbwg1.5_mpostnatal body weight growth 1.5 (mouse)Not determined4352061277520756Mouse
1558820Moo1_mmodifier of Odc1 (mouse)Not determined174826974682269934Mouse
13432184Actdes1_mactivity chamber total difference ethanol/saline 1 (mouse)25939228769292287Mouse
1300645Alcp1_malcohol preference locus 1 (mouse)Not determined24522812867838868Mouse
13432180Acq2_mactivity chamber QTL 2 (mouse)26079228764592287Mouse
4141186Pbwg1.8_mpostnatal body weight growth 1.8 (mouse)Not determined3579732469797406Mouse
13432178Actres2_mactivity response to ethanol/saline 2 (mouse)26069228774092287Mouse
12738429Lfibq18_mliver fibrosis QTL 18 (mouse)25791999191919991Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
11038703Ltpr1_mLeishmania tropica response 1 (mouse)23997166573971811Mouse
1300568Hdl1_mhigh density lipoprotein (HDL) level 1 (mouse)Not determined24826974682269934Mouse
1559001Eae33_mexperimental allergic encephalomyelitis susceptibility 33 (mouse)Not determined23599167971609412Mouse
4142447Pbwg1.7_mpostnatal body weight growth 1.7 (mouse)Not determined3579732469797406Mouse
1301703Bomd3_mbone mineral density 3 (mouse)Not determined26300595497006113Mouse
4142185Pbwg1.3_mpostnatal body weight growth 1.3 (mouse)Not determined5718712365132495Mouse
10449151Hdl8_mhigh density lipoprotein (HDL) level 8 (mouse)23812972567072607Mouse
1301747Eae21_mexperimental allergic encephalomyelitis 21 (mouse)Not determined24826974682269934Mouse
1301235Alcw4_malcohol withdrawal 4 (mouse)Not determined24826974682269934Mouse
10449150Pvldlc1_mplasma VLDL-cholesterol 1 (mouse)23812972567072607Mouse
4141406Alpq2_malcohol preference QTL 2 (mouse)Not determined25752411791524288Mouse
10755526Lymph1_mlymphocyte differential 1 (mouse)25081931484819314Mouse
13463471Hctq6_mhematocrit QTL 6 (mouse)25244801986448136Mouse
1301873Hsl1_mhyperoxia susceptibility locus 1 (mouse)Not determined26357015497570301Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
10449145Lanq1_mlanosterol level QTL 1 (mouse)23812972567072607Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
10755532Lymph5_mlymphocyte differential 5 (mouse)24419901778199017Mouse
11532740Pbwg1.10_mpostnatal body weight growth 1.10 (mouse)24813241282132495Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
1301480Pbwg1_mpostnatal body weight growth 1 (mouse)Not determined24182071975820843Mouse
10044002Hdl7_mHDL level 7 (mouse)Not determined26300595497006113Mouse

Markers in Region
FIGN__6723  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38263,978,578 - 63,979,182UniSTSGRCm38
MGSCv37263,816,635 - 63,817,239UniSTSGRCm37
Celera265,663,969 - 65,664,573UniSTS
Cytogenetic Map2C1.3UniSTS
AU022255  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38264,021,740 - 64,021,957UniSTSGRCm38
MGSCv37263,859,797 - 63,860,014UniSTSGRCm37
Celera265,707,125 - 65,707,342UniSTS
Cytogenetic Map2C1.3UniSTS
Whitehead/MRC_RH21022.38UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001267846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001267847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF263913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF282175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF282176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF282718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF282719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL772173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL928553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000102728   ⟹   ENSMUSP00000124338
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl263,807,681 - 63,928,382 (-)Ensembl
GRCm38.p6 Ensembl263,977,337 - 64,098,038 (-)Ensembl
Ensembl Acc Id: ENSMUST00000126042
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl263,810,791 - 63,928,332 (-)Ensembl
GRCm38.p6 Ensembl263,980,447 - 64,097,988 (-)Ensembl
Ensembl Acc Id: ENSMUST00000131615   ⟹   ENSMUSP00000122855
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl263,801,851 - 63,928,356 (-)Ensembl
GRCm38.p6 Ensembl263,971,507 - 64,098,012 (-)Ensembl
Ensembl Acc Id: ENSMUST00000153538
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl263,810,960 - 63,928,354 (-)Ensembl
GRCm38.p6 Ensembl263,980,616 - 64,098,010 (-)Ensembl
RefSeq Acc Id: NM_001267846   ⟹   NP_001254775
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39263,801,852 - 63,928,382 (-)NCBI
GRCm38263,971,508 - 64,098,038 (-)NCBI
Celera265,657,016 - 65,783,609 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001267847   ⟹   NP_001254776
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39263,801,852 - 63,928,382 (-)NCBI
GRCm38263,971,508 - 64,098,038 (-)NCBI
Celera265,657,016 - 65,783,609 (-)NCBI
Sequence:
RefSeq Acc Id: NM_021716   ⟹   NP_068362
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39263,801,852 - 63,928,382 (-)NCBI
GRCm38263,971,508 - 64,098,038 (-)NCBI
MGSCv37263,815,418 - 63,936,064 (-)RGD
Celera265,657,016 - 65,783,609 (-)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_068362   ⟸   NM_021716
- Peptide Label: isoform 1
- UniProtKB: Q9ERZ6 (UniProtKB/Swiss-Prot),   Q6PCM0 (UniProtKB/Swiss-Prot),   Q3UP57 (UniProtKB/Swiss-Prot),   Q3TPB0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001254776   ⟸   NM_001267847
- Peptide Label: isoform 2
- UniProtKB: Q9ERZ6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001254775   ⟸   NM_001267846
- Peptide Label: isoform 2
- UniProtKB: Q9ERZ6 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000122855   ⟸   ENSMUST00000131615
Ensembl Acc Id: ENSMUSP00000124338   ⟸   ENSMUST00000102728

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ERZ6-F1-model_v2 AlphaFold Q9ERZ6 1-759 view protein structure

Promoters
RGD ID:6831371
Promoter ID:MM_KWN:29428
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver,   MEF_B6
Transcripts:ENSMUST00000102728,   OTTMUST00000030614,   OTTMUST00000030615,   OTTMUST00000030616
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36263,935,821 - 63,936,321 (-)MPROMDB
RGD ID:6877434
Promoter ID:EPDNEW_M2168
Type:initiation region
Name:Fign_2
Description:Mus musculus fidgetin , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2169  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38264,062,152 - 64,062,212EPDNEW
RGD ID:6877436
Promoter ID:EPDNEW_M2169
Type:multiple initiation site
Name:Fign_1
Description:Mus musculus fidgetin , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2168  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38264,098,006 - 64,098,066EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1890647 AgrOrtholog
Ensembl Genes ENSMUSG00000075324 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000131615 ENTREZGENE
  ENSMUST00000131615.9 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.8.60 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
InterPro AAA+_ATPase UniProtKB/Swiss-Prot
  ATPase_AAA_core UniProtKB/Swiss-Prot
  ATPase_AAA_CS UniProtKB/Swiss-Prot
  Fidgetin_ATPase UniProtKB/Swiss-Prot
  MT-severing_AAA_ATPase UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  Vps4_C UniProtKB/Swiss-Prot
KEGG Report mmu:60344 UniProtKB/Swiss-Prot
MGD MGI:1890647 ENTREZGENE
NCBI Gene Fign ENTREZGENE
PANTHER AAA DOMAIN-CONTAINING UniProtKB/Swiss-Prot
  FIDGETIN UniProtKB/Swiss-Prot
Pfam AAA UniProtKB/Swiss-Prot
  Vps4_C UniProtKB/Swiss-Prot
PhenoGen Fign PhenoGen
PROSITE AAA UniProtKB/Swiss-Prot
SMART AAA UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt E0CYB7_MOUSE UniProtKB/TrEMBL
  FIGN_MOUSE UniProtKB/Swiss-Prot
  Q3TPB0 ENTREZGENE
  Q3UP57 ENTREZGENE
  Q6PCM0 ENTREZGENE
  Q9ERZ6 ENTREZGENE
UniProt Secondary Q3TPB0 UniProtKB/Swiss-Prot
  Q3UP57 UniProtKB/Swiss-Prot
  Q6PCM0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-09-09 Fign  fidgetin  fi  fidget  Symbol and/or name updated 27372883 PROVISIONAL
2024-09-04 fi  fidget  Fign  fidgetin  Symbol and/or name change 5135510 APPROVED
2024-08-21 Fign  fidgetin  fi  fidget  Symbol and/or name change 5135510 APPROVED
2024-08-21 fi  fidget  Fign  fidgetin  Symbol and/or name change 5135510 APPROVED