Cul1 (cullin 1) - Rat Genome Database

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Gene: Cul1 (cullin 1) Mus musculus
Analyze
Symbol: Cul1
Name: cullin 1
RGD ID: 1317769
MGI Page MGI
Description: Predicted to enable ubiquitin ligase complex scaffold activity and ubiquitin protein ligase binding activity. Predicted to contribute to ubiquitin protein ligase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Acts upstream of or within several processes, including apoptotic process; cell population proliferation; and protein ubiquitination. Part of SCF ubiquitin ligase complex. Is expressed in several structures, including adrenal gland; genitourinary system; immune system; neural retina; and telencephalon. Orthologous to human CUL1 (cullin 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CUL-1; cullin-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm17842  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39647,430,516 - 47,503,078 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl647,430,332 - 47,503,073 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38647,453,732 - 47,526,144 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl647,453,398 - 47,526,139 (+)Ensemblmm10GRCm38
MGSCv37647,404,323 - 47,476,138 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36647,383,910 - 47,455,725 (+)NCBIMGSCv36mm8
Celera647,309,280 - 47,381,243 (+)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map622.9NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Hayes JD and Dinkova-Kostova AT, Trends Biochem Sci. 2014 Apr;39(4):199-218. doi: 10.1016/j.tibs.2014.02.002. Epub 2014 Mar 16.
2. Expanding role of ubiquitination in NF-kappaB signaling. Liu S and Chen ZJ, Cell Res. 2011 Jan;21(1):6-21. Epub 2010 Dec 7.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1). Morimoto M, etal., Biochem Biophys Res Commun. 2000 Apr 21;270(3):1093-6.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9663463   PMID:10097128   PMID:10349636   PMID:10508527   PMID:10531039   PMID:10585767   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11735228  
PMID:11967155   PMID:12140560   PMID:12393444   PMID:12417738   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12665572   PMID:14610273   PMID:14701835   PMID:14764675   PMID:15226823  
PMID:15299027   PMID:15456869   PMID:15489334   PMID:15531760   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16880526   PMID:17215248   PMID:17242400   PMID:17290223   PMID:17318263  
PMID:17636028   PMID:17803915   PMID:18287559   PMID:18799693   PMID:18826954   PMID:18929646   PMID:19398581   PMID:19521500   PMID:19576224   PMID:20832730   PMID:20937703   PMID:21267068  
PMID:21343341   PMID:21368834   PMID:21873635   PMID:22033112   PMID:22405651   PMID:22466964   PMID:22673621   PMID:22955283   PMID:23452856   PMID:23868976   PMID:24085301   PMID:24390425  
PMID:24457600   PMID:25670854   PMID:26418746   PMID:26471094   PMID:26496610   PMID:27063938   PMID:27224922   PMID:27309807   PMID:29472293   PMID:29593216   PMID:30713523   PMID:31146259  
PMID:31167929   PMID:31898227   PMID:32232159   PMID:32325033   PMID:32937135   PMID:33020269   PMID:33933992   PMID:34321999   PMID:35115401   PMID:37063418   PMID:37442135   PMID:37528093  
PMID:39003567  


Genomics

Comparative Map Data
Cul1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39647,430,516 - 47,503,078 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl647,430,332 - 47,503,073 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38647,453,732 - 47,526,144 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl647,453,398 - 47,526,139 (+)Ensemblmm10GRCm38
MGSCv37647,404,323 - 47,476,138 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36647,383,910 - 47,455,725 (+)NCBIMGSCv36mm8
Celera647,309,280 - 47,381,243 (+)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map622.9NCBI
CUL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387148,697,756 - 148,801,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7148,697,914 - 148,801,110 (+)Ensemblhg38GRCh38
GRCh377148,394,848 - 148,498,202 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367148,026,866 - 148,129,135 (+)NCBIBuild 36Build 36hg18NCBI36
Build 347147,833,580 - 147,935,849NCBI
Celera7143,066,358 - 143,168,625 (+)NCBICelera
Cytogenetic Map7q36.1NCBI
HuRef7142,474,925 - 142,577,198 (+)NCBIHuRef
CHM1_17148,404,339 - 148,506,599 (+)NCBICHM1_1
T2T-CHM13v2.07149,879,652 - 149,982,884 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27147,733,888 - 147,836,155 (+)NCBI
Cul1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8477,551,781 - 77,634,210 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl477,551,787 - 77,621,760 (+)EnsemblGRCr8
mRatBN7.2476,551,952 - 76,625,830 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl476,551,983 - 76,627,980 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx481,518,199 - 81,586,396 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0477,431,538 - 77,499,741 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0475,811,714 - 75,879,914 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0477,211,814 - 77,283,369 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl477,211,692 - 77,280,250 (+)Ensemblrn6Rnor6.0
Rnor_5.04141,883,675 - 141,954,829 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4475,636,914 - 75,705,724 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera471,356,492 - 71,424,907 (+)NCBICelera
RGSC_v3.1475,913,432 - 75,981,935 (+)NCBI
Cytogenetic Map4q24NCBI
Cul1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554914,165,561 - 4,212,054 (+)Ensembl
ChiLan1.0NW_0049554914,165,400 - 4,212,483 (+)NCBIChiLan1.0ChiLan1.0
CUL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26185,284,645 - 185,386,756 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1737,293,911 - 37,397,018 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07140,428,442 - 140,531,136 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17152,907,803 - 153,011,254 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7152,908,303 - 153,011,254 (+)EnsemblpanPan2panpan1.1
CUL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1161,995,637 - 2,086,853 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl161,995,960 - 2,052,864 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha163,094,500 - 3,190,996 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0161,800,318 - 1,893,359 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl161,800,261 - 1,893,706 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1161,786,922 - 1,879,856 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0161,646,255 - 1,739,205 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0161,650,453 - 1,743,455 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cul1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051187,883,967 - 7,967,988 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365274,971,000 - 5,019,562 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365274,971,002 - 5,019,465 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CUL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9109,454,534 - 109,557,649 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.19109,454,523 - 109,559,114 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29120,392,339 - 120,495,724 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CUL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121117,271,477 - 117,373,983 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21117,271,548 - 117,374,379 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607213,218,021 - 13,323,070 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cul1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248006,877,986 - 6,978,587 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cul1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1693,226,734 - 93,295,038 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cul1
2625 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:966
Count of miRNA genes:525
Interacting mature miRNAs:638
Transcripts:ENSMUST00000031697, ENSMUST00000126877, ENSMUST00000143941, ENSMUST00000146200, ENSMUST00000146828, ENSMUST00000149531, ENSMUST00000151934, ENSMUST00000152547, ENSMUST00000154201, ENSMUST00000154391
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1771159851711719Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64380374777788506Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64380374777788506Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
14746995Manh60_mmandible shape 60 (mouse)63720266271202662Mouse
12910807Pwbwq11_mpost-weaning body weight QTL 11 (mouse)64380374777788506Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
12910802Pwbwq12_mpost-weaning body weight QTL 12 (mouse)64380374777788506Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3674146370741463Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64529099387403016Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2829099362291115Mouse
12910809Pwbwq10_mpost-weaning body weight QTL 10 (mouse)64380374777788506Mouse
12910820Ogrq3_moverall growth rate QTL 3 (mouse)64380374777788506Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61961634653616346Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61961634653616346Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3170349965703611Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61961634653616346Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348703611Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348703611Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61771159851711719Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63387226167872400Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61771159851711719Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62004983054049830Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348703611Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64086823071356155Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3282758578215957Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64157698575576985Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63267698066676980Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64209335876093500Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64209335876093500Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62377693457776934Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64209335876093500Mouse
10043885Cia6c_mcollagen induced arthritis QTL 6c (mouse)Not determined64444280571096451Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63644845670448576Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61769999953476985Mouse

Markers in Region
AW743318  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38647,522,549 - 47,522,800UniSTSGRCm38
MGSCv37647,472,548 - 47,472,799UniSTSGRCm37
Celera647,377,654 - 47,377,905UniSTS
Cytogenetic Map6B3UniSTS
Whitehead/MRC_RH6439.51UniSTS
MHAa27b4.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38647,463,917 - 47,464,068UniSTSGRCm38
MGSCv37647,413,916 - 47,414,067UniSTSGRCm37
Celera647,318,868 - 47,319,019UniSTS
Cytogenetic Map6B3UniSTS
Whitehead_YAC6 UniSTS
D6Mit352  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38647,469,256 - 47,469,364UniSTSGRCm38
MGSCv37647,419,255 - 47,419,363UniSTSGRCm37
Celera647,324,429 - 47,324,537UniSTS
Cytogenetic Map6B3UniSTS
cM Map620.4UniSTS
Whitehead Genetic610.9UniSTS
Whitehead/MRC_RH6437.08UniSTS
Whitehead_YAC6 UniSTS
D6Dcr7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38647,469,253 - 47,469,361UniSTSGRCm38
MGSCv37647,419,252 - 47,419,360UniSTSGRCm37
Celera647,324,426 - 47,324,534UniSTS
Cytogenetic Map6B3UniSTS
cM Map6 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001355550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001355551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_012042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC154014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF083216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF136441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF176910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000031697   ⟹   ENSMUSP00000031697
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl647,431,254 - 47,503,073 (+)Ensembl
GRCm38.p6 Ensembl647,454,320 - 47,526,139 (+)Ensembl
Ensembl Acc Id: ENSMUST00000126877
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl647,491,743 - 47,502,992 (+)Ensembl
GRCm38.p6 Ensembl647,514,809 - 47,526,058 (+)Ensembl
Ensembl Acc Id: ENSMUST00000143941   ⟹   ENSMUSP00000144845
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl647,431,322 - 47,462,111 (+)Ensembl
GRCm38.p6 Ensembl647,454,388 - 47,485,177 (+)Ensembl
Ensembl Acc Id: ENSMUST00000146200   ⟹   ENSMUSP00000122702
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl647,430,838 - 47,500,700 (+)Ensembl
GRCm38.p6 Ensembl647,453,904 - 47,523,766 (+)Ensembl
Ensembl Acc Id: ENSMUST00000146828   ⟹   ENSMUSP00000121608
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl647,430,332 - 47,474,171 (+)Ensembl
GRCm38.p6 Ensembl647,453,398 - 47,497,237 (+)Ensembl
Ensembl Acc Id: ENSMUST00000149531
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl647,500,498 - 47,502,713 (+)Ensembl
GRCm38.p6 Ensembl647,523,564 - 47,525,779 (+)Ensembl
Ensembl Acc Id: ENSMUST00000151934
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl647,493,926 - 47,496,713 (+)Ensembl
GRCm38.p6 Ensembl647,516,992 - 47,519,779 (+)Ensembl
Ensembl Acc Id: ENSMUST00000152547   ⟹   ENSMUSP00000114959
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl647,430,426 - 47,461,899 (+)Ensembl
GRCm38.p6 Ensembl647,453,492 - 47,484,965 (+)Ensembl
Ensembl Acc Id: ENSMUST00000154201
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl647,496,630 - 47,500,215 (+)Ensembl
GRCm38.p6 Ensembl647,519,696 - 47,523,281 (+)Ensembl
RefSeq Acc Id: NM_001355550   ⟹   NP_001342479
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39647,431,630 - 47,503,078 (+)NCBI
GRCm38647,454,757 - 47,526,144 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001355551   ⟹   NP_001342480
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39647,430,855 - 47,503,078 (+)NCBI
GRCm38647,453,732 - 47,526,144 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001410599   ⟹   NP_001397528
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39647,430,516 - 47,503,078 (+)NCBI
RefSeq Acc Id: NM_001410600   ⟹   NP_001397529
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39647,430,855 - 47,503,078 (+)NCBI
RefSeq Acc Id: NM_001410601   ⟹   NP_001397530
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39647,431,350 - 47,503,078 (+)NCBI
RefSeq Acc Id: NM_001410602   ⟹   NP_001397531
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39647,438,805 - 47,503,078 (+)NCBI
RefSeq Acc Id: NM_012042   ⟹   NP_036172
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39647,431,350 - 47,503,078 (+)NCBI
GRCm38647,454,319 - 47,526,144 (+)NCBI
MGSCv37647,404,323 - 47,476,138 (+)RGD
Celera647,309,280 - 47,381,243 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_036172   ⟸   NM_012042
- UniProtKB: Q9WUI7 (UniProtKB/Swiss-Prot),   Q9WTX6 (UniProtKB/Swiss-Prot),   Q3UIA5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001342480   ⟸   NM_001355551
- UniProtKB: Q9WTX6 (UniProtKB/Swiss-Prot),   Q9WUI7 (UniProtKB/Swiss-Prot),   Q3UIA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001342479   ⟸   NM_001355550
- UniProtKB: Q9WTX6 (UniProtKB/Swiss-Prot),   Q9WUI7 (UniProtKB/Swiss-Prot),   Q3UIA5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000031697   ⟸   ENSMUST00000031697
Ensembl Acc Id: ENSMUSP00000144845   ⟸   ENSMUST00000143941
Ensembl Acc Id: ENSMUSP00000114959   ⟸   ENSMUST00000152547
Ensembl Acc Id: ENSMUSP00000121608   ⟸   ENSMUST00000146828
Ensembl Acc Id: ENSMUSP00000122702   ⟸   ENSMUST00000146200
RefSeq Acc Id: NP_001397528   ⟸   NM_001410599
- UniProtKB: Q9WTX6 (UniProtKB/Swiss-Prot),   Q9WUI7 (UniProtKB/Swiss-Prot),   Q3UIA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397529   ⟸   NM_001410600
- UniProtKB: Q9WTX6 (UniProtKB/Swiss-Prot),   Q9WUI7 (UniProtKB/Swiss-Prot),   Q3UIA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397530   ⟸   NM_001410601
- UniProtKB: Q9WTX6 (UniProtKB/Swiss-Prot),   Q9WUI7 (UniProtKB/Swiss-Prot),   Q3UIA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397531   ⟸   NM_001410602
- UniProtKB: Q9WTX6 (UniProtKB/Swiss-Prot),   Q9WUI7 (UniProtKB/Swiss-Prot),   Q3UIA5 (UniProtKB/TrEMBL)
Protein Domains
Cullin family profile   Cullin N-terminal   Cullin neddylation

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WTX6-F1-model_v2 AlphaFold Q9WTX6 1-776 view protein structure

Promoters
RGD ID:6839143
Promoter ID:MM_KWN:45846
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Lung
Transcripts:OTTMUST00000053240,   OTTMUST00000053242,   OTTMUST00000053243,   OTTMUST00000053244,   OTTMUST00000053245,   UC009BSZ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36647,404,156 - 47,404,656 (+)MPROMDB
RGD ID:6889560
Promoter ID:EPDNEW_M8231
Type:initiation region
Name:Cul1_2
Description:Mus musculus cullin 1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8232  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38647,453,921 - 47,453,981EPDNEW
RGD ID:6889562
Promoter ID:EPDNEW_M8232
Type:initiation region
Name:Cul1_1
Description:Mus musculus cullin 1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8231  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38647,454,416 - 47,454,476EPDNEW
RGD ID:6839149
Promoter ID:MM_KWN:45849
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   Lung
Transcripts:OTTMUST00000053562
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36647,466,894 - 47,467,394 (+)MPROMDB
RGD ID:6839146
Promoter ID:MM_KWN:45850
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:OTTMUST00000053246
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36647,469,146 - 47,469,646 (+)MPROMDB
RGD ID:6839147
Promoter ID:MM_KWN:45851
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4,   BoneMarrow_0Hour
Transcripts:OTTMUST00000053247
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36647,472,679 - 47,473,179 (+)MPROMDB
RGD ID:6847990
Promoter ID:MM_ACW:41121
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_2Hour,   MEF_B6
Transcripts:CUL1.JSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36647,475,671 - 47,476,171 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1349658 AgrOrtholog
Ensembl Genes ENSMUSG00000029686 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000031697 ENTREZGENE
  ENSMUST00000031697.9 UniProtKB/Swiss-Prot
  ENSMUST00000146200 ENTREZGENE
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot
  Cullin Repeats UniProtKB/Swiss-Prot
  Ring Box Chain A, domain 5 UniProtKB/Swiss-Prot
InterPro Cullin UniProtKB/Swiss-Prot
  Cullin_CS UniProtKB/Swiss-Prot
  Cullin_homology UniProtKB/Swiss-Prot
  Cullin_homology_sf UniProtKB/Swiss-Prot
  Cullin_N UniProtKB/Swiss-Prot
  Cullin_neddylation_domain UniProtKB/Swiss-Prot
  Cullin_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot
  WH_DNA-bd_sf UniProtKB/Swiss-Prot
KEGG Report mmu:26965 UniProtKB/Swiss-Prot
MGD MGI:1349658 ENTREZGENE
NCBI Gene 26965 ENTREZGENE
PANTHER PTHR11932 UniProtKB/Swiss-Prot
Pfam Cullin UniProtKB/Swiss-Prot
  Cullin_Nedd8 UniProtKB/Swiss-Prot
PhenoGen Cul1 PhenoGen
PROSITE CULLIN_1 UniProtKB/Swiss-Prot
  CULLIN_2 UniProtKB/Swiss-Prot
SMART CULLIN UniProtKB/Swiss-Prot
  Cullin_Nedd8 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot
  SSF74788 UniProtKB/Swiss-Prot
  SSF75632 UniProtKB/Swiss-Prot
UniProt A0A0N4SUW1_MOUSE UniProtKB/TrEMBL
  CUL1_MOUSE UniProtKB/Swiss-Prot
  D3YUS8_MOUSE UniProtKB/TrEMBL
  D3Z2H3_MOUSE UniProtKB/TrEMBL
  Q05DR6_MOUSE UniProtKB/TrEMBL
  Q3TPM3_MOUSE UniProtKB/TrEMBL
  Q3UIA5 ENTREZGENE, UniProtKB/TrEMBL
  Q9WTX6 ENTREZGENE
  Q9WUI7 ENTREZGENE
UniProt Secondary Q9WUI7 UniProtKB/Swiss-Prot