Nelfb (negative elongation factor complex member B) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Nelfb (negative elongation factor complex member B) Mus musculus
Analyze
Symbol: Nelfb
Name: negative elongation factor complex member B
RGD ID: 1317256
MGI Page MGI
Description: Predicted to enable RNA binding activity. Involved in several processes, including negative regulation of stem cell differentiation; negative regulation of transcription elongation by RNA polymerase II; and stem cell differentiation. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of NELF complex. Is expressed in several structures, including blastocyst; early embryo; and gonad. Orthologous to human NELFB (negative elongation factor complex member B).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: A730008L03Rik; AB041607; AI663983; Cob; Cobra1; cofactor of BRCA1; negative elongation factor B; negative elongation factor complex member B, Cobra1; Nelf-b; ortholog of human cofactor of BRCA1 (COBRA1); RP23-132N23.4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39225,089,724 - 25,101,501 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl225,089,724 - 25,101,501 (-)EnsemblGRCm39 Ensembl
GRCm38225,199,712 - 25,211,489 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl225,199,712 - 25,211,489 (-)EnsemblGRCm38mm10GRCm38
MGSCv37225,055,232 - 25,067,009 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36225,021,726 - 25,033,390 (-)NCBIMGSCv36mm8
Celera224,927,483 - 24,939,264 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map217.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Control of transcriptional elongation. Kwak H and Lis JT, Annu Rev Genet. 2013;47:483-508. doi: 10.1146/annurev-genet-110711-155440. Epub 2013 Sep 11.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12520002   PMID:15368895   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:19340312   PMID:20059953   PMID:21267068   PMID:21677750   PMID:21865163   PMID:21873635   PMID:23950223   PMID:24034695   PMID:24656816   PMID:25773599   PMID:26010750   PMID:26941120  
PMID:28649985   PMID:29424686   PMID:29426838   PMID:30036938   PMID:30196744   PMID:30332301   PMID:32325033   PMID:32385332   PMID:33735618   PMID:35444206   PMID:35981753   PMID:36577375  
PMID:37717699   PMID:38287033  


Genomics

Comparative Map Data
Nelfb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39225,089,724 - 25,101,501 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl225,089,724 - 25,101,501 (-)EnsemblGRCm39 Ensembl
GRCm38225,199,712 - 25,211,489 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl225,199,712 - 25,211,489 (-)EnsemblGRCm38mm10GRCm38
MGSCv37225,055,232 - 25,067,009 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36225,021,726 - 25,033,390 (-)NCBIMGSCv36mm8
Celera224,927,483 - 24,939,264 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map217.06NCBI
NELFB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389137,255,327 - 137,273,542 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9137,255,327 - 137,273,542 (+)EnsemblGRCh38hg38GRCh38
GRCh379140,149,779 - 140,167,994 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369139,269,768 - 139,287,815 (+)NCBINCBI36Build 36hg18NCBI36
Celera9110,665,618 - 110,683,794 (+)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,609,072 - 109,627,292 (+)NCBIHuRef
CHM1_19140,298,493 - 140,316,577 (+)NCBICHM1_1
T2T-CHM13v2.09149,492,996 - 149,511,192 (+)NCBIT2T-CHM13v2.0
Nelfb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,409,045 - 28,425,564 (-)NCBIGRCr8
mRatBN7.238,010,883 - 8,027,403 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,010,888 - 8,027,403 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx311,115,610 - 11,132,086 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,701,839 - 19,718,315 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0317,891,682 - 17,908,158 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,414,448 - 2,431,148 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,414,451 - 2,431,148 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.032,395,734 - 2,412,431 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,360,222 - 3,376,609 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.133,360,218 - 3,376,563 (-)NCBI
Celera32,837,727 - 2,854,117 (-)NCBICelera
Cytogenetic Map3p13NCBI
Nelfb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555135,248,190 - 5,262,044 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555135,248,190 - 5,261,018 (+)NCBIChiLan1.0ChiLan1.0
NELFB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2112,126,248 - 2,144,680 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan192,128,581 - 2,147,028 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09108,314,535 - 108,333,050 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19137,283,264 - 137,301,751 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9137,278,964 - 137,301,751 (+)Ensemblpanpan1.1panPan2
NELFB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,411,725 - 48,425,044 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,408,005 - 48,423,308 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha947,598,208 - 47,608,900 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0949,273,065 - 49,283,756 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,206,548 - 49,287,069 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,049,494 - 48,060,162 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,348,232 - 48,358,986 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,395,161 - 48,405,870 (-)NCBIUU_Cfam_GSD_1.0
Nelfb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,636,347 - 202,648,327 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936669726,658 - 738,848 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936669726,731 - 738,714 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NELFB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.21314,117,252 - 314,125,940 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NELFB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112914,384 - 933,921 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660584,373,307 - 4,392,656 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nelfb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624760692,735 - 705,328 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624760692,735 - 703,571 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nelfb
548 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1436
Count of miRNA genes:611
Interacting mature miRNAs:756
Transcripts:ENSMUST00000059849, ENSMUST00000124900, ENSMUST00000128876, ENSMUST00000129140, ENSMUST00000138199, ENSMUST00000140934, ENSMUST00000146729, ENSMUST00000147890
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552706Cia24_mcollagen induced arthritis QTL 24 (mouse)Not determined22467911533523172Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
4142333Tgq10_mtriglyceride QTL 10 (mouse)Not determined125324559Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2938444643384575Mouse
8552705Cia25_mcollagen induced arthritis 25 (mouse)Not determined22467911533523172Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22459001254890012Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2823629642236396Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2767911541679261Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22112972555129871Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
12792980Fbmd1_mfemoral bone mineral density 1, females only (mouse)22503449245034492Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21421456748214713Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301838Sluc16_msusceptibility to lung cancer 16 (mouse)Not determined2126529589Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2938444643384575Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
12904743Carcdq3_mcardiac collagen deposition QTL 3 (mouse)2323494028179150Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22368914557689269Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
4141836Tgq11_mtriglyceride QTL 11 (mouse)Not determined125324559Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2112972555129871Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2830805142308240Mouse
12903993Opfaq1_mopen field activity QTL 1 (mouse)2967669127022642Mouse

Markers in Region
RH136194  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38225,200,427 - 25,201,094UniSTSGRCm38
MGSCv37225,055,947 - 25,056,614UniSTSGRCm37
Celera224,928,198 - 24,928,865UniSTS
Cytogenetic Map2A3UniSTS
Cobra1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2A3UniSTS
cM Map2 UniSTS
cM Map217.06UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001310157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB041607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI843129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK173124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL732309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU519080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY721962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ100279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX241076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000059849   ⟹   ENSMUSP00000057731
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl225,089,724 - 25,101,501 (-)Ensembl
GRCm38.p6 Ensembl225,199,712 - 25,211,489 (-)Ensembl
Ensembl Acc Id: ENSMUST00000124900   ⟹   ENSMUSP00000115296
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl225,090,697 - 25,093,933 (-)Ensembl
GRCm38.p6 Ensembl225,200,685 - 25,203,921 (-)Ensembl
Ensembl Acc Id: ENSMUST00000128876
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl225,089,728 - 25,101,393 (-)Ensembl
GRCm38.p6 Ensembl225,199,716 - 25,211,381 (-)Ensembl
Ensembl Acc Id: ENSMUST00000129140
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl225,090,050 - 25,093,805 (-)Ensembl
GRCm38.p6 Ensembl225,200,038 - 25,203,793 (-)Ensembl
Ensembl Acc Id: ENSMUST00000138199
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl225,093,963 - 25,100,086 (-)Ensembl
GRCm38.p6 Ensembl225,203,951 - 25,210,074 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140934   ⟹   ENSMUSP00000115698
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl225,093,903 - 25,100,738 (-)Ensembl
GRCm38.p6 Ensembl225,203,891 - 25,210,726 (-)Ensembl
Ensembl Acc Id: ENSMUST00000146729
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl225,091,166 - 25,093,613 (-)Ensembl
GRCm38.p6 Ensembl225,201,154 - 25,203,601 (-)Ensembl
Ensembl Acc Id: ENSMUST00000147890
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl225,095,179 - 25,100,712 (-)Ensembl
GRCm38.p6 Ensembl225,205,167 - 25,210,700 (-)Ensembl
RefSeq Acc Id: NM_001310157   ⟹   NP_001297086
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39225,089,724 - 25,101,501 (-)NCBI
GRCm38225,199,712 - 25,211,489 (-)NCBI
Sequence:
RefSeq Acc Id: NM_021393   ⟹   NP_067368
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39225,089,724 - 25,101,501 (-)NCBI
GRCm38225,199,712 - 25,211,489 (-)ENTREZGENE
MGSCv37225,055,232 - 25,067,009 (-)RGD
Celera224,927,483 - 24,939,264 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_067368   ⟸   NM_021393
- Peptide Label: isoform 1
- UniProtKB: A0A5H1ZRL3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001297086   ⟸   NM_001310157
- Peptide Label: isoform 2
- UniProtKB: Q8C4Y3 (UniProtKB/Swiss-Prot),   Q9JJA5 (UniProtKB/Swiss-Prot),   Q99J41 (UniProtKB/Swiss-Prot),   A0A0X1KG62 (UniProtKB/Swiss-Prot),   Q69ZP4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000115296   ⟸   ENSMUST00000124900
Ensembl Acc Id: ENSMUSP00000057731   ⟸   ENSMUST00000059849
Ensembl Acc Id: ENSMUSP00000115698   ⟸   ENSMUST00000140934

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C4Y3-F1-model_v2 AlphaFold Q8C4Y3 1-580 view protein structure

Promoters
RGD ID:6831054
Promoter ID:MM_KWN:28098
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung
Transcripts:OTTMUST00000027713,   OTTMUST00000027714,   OTTMUST00000027715
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36225,058,736 - 25,059,667 (-)MPROMDB
RGD ID:6831052
Promoter ID:MM_KWN:28100
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_021393,   OTTMUST00000027649,   OTTMUST00000027710,   OTTMUST00000027711,   OTTMUST00000027712
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36225,066,496 - 25,067,137 (-)MPROMDB
RGD ID:6876552
Promoter ID:EPDNEW_M1727
Type:initiation region
Name:Nelfb_1
Description:Mus musculus negative elongation factor complex member B , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38225,211,389 - 25,211,449EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1931035 AgrOrtholog
Ensembl Genes ENSMUSG00000013465 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000059849 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000059849.15 UniProtKB/Swiss-Prot
  ENSMUST00000124900.2 UniProtKB/TrEMBL
  ENSMUST00000128876 ENTREZGENE
  ENSMUST00000140934.2 UniProtKB/TrEMBL
InterPro COBRA1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:58202 UniProtKB/Swiss-Prot
MGD MGI:1931035 ENTREZGENE
NCBI Gene 58202 ENTREZGENE
PANTHER NEGATIVE ELONGATION FACTOR B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13503 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam COBRA1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nelfb PhenoGen
UniProt A0A0X1KG62 ENTREZGENE
  A0A5H1ZRL3 ENTREZGENE, UniProtKB/TrEMBL
  F6SWS9_MOUSE UniProtKB/TrEMBL
  F6UFF7_MOUSE UniProtKB/TrEMBL
  NELFB_MOUSE UniProtKB/Swiss-Prot
  Q69ZP4 ENTREZGENE
  Q8C4Y3 ENTREZGENE
  Q99J41 ENTREZGENE
  Q9JJA5 ENTREZGENE
UniProt Secondary A0A0X1KG62 UniProtKB/Swiss-Prot
  Q69ZP4 UniProtKB/Swiss-Prot
  Q99J41 UniProtKB/Swiss-Prot
  Q9JJA5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-09-03 Nelfb  negative elongation factor complex member B    negative elongation factor complex member B, Cobra1  Symbol and/or name change 5135510 APPROVED
2013-02-20 Nelfb  negative elongation factor complex member B, Cobra1  Cobra1  cofactor of BRCA1  Symbol and/or name change 5135510 APPROVED