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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nelfb | Mouse | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NELFB mRNA | CTD | PMID:22206623 | Nelfb | Mouse | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of NELFB mRNA | CTD | PMID:22206623 | Nelfb | Mouse | 17beta-estradiol | multiple interactions | ISO | NELFB (Homo sapiens) | 6480464 | Estradiol affects the reaction [ESR1 protein binds to NELFB protein] and Estradiol promotes the reaction [ESR1 protein binds to NELFB protein] | CTD | PMID:23665804 more ... | Nelfb | Mouse | 17beta-estradiol | increases expression | ISO | Nelfb (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of NELFB mRNA | CTD | PMID:32145629 | Nelfb | Mouse | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | multiple interactions | ISO | NELFB (Homo sapiens) | 6480464 | [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NELFB protein modified form] | CTD | PMID:28751236 | Nelfb | Mouse | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | NELFB (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Nelfb | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NELFB mRNA | CTD | PMID:21354282 | Nelfb | Mouse | 2,4,6-tribromophenol | increases expression | ISO | NELFB (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Nelfb | Mouse | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | NELFB (Homo sapiens) | 6480464 | tetrabromobisphenol A results in increased expression of NELFB protein | CTD | PMID:31675489 | Nelfb | Mouse | 4,4'-sulfonyldiphenol | multiple interactions | ISO | NELFB (Homo sapiens) | 6480464 | bisphenol S inhibits the reaction [ESR1 protein binds to NELFB protein] | CTD | PMID:29389661 | Nelfb | Mouse | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of NELFB gene | CTD | PMID:31683443 | Nelfb | Mouse | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Nelfb (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of NELFB mRNA | CTD | PMID:36041667 | Nelfb | Mouse | antirheumatic drug | increases expression | ISO | NELFB (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of NELFB mRNA | CTD | PMID:24449571 | Nelfb | Mouse | arsane | affects methylation | ISO | NELFB (Homo sapiens) | 6480464 | Arsenic affects the methylation of NELFB gene | CTD | PMID:25304211 | Nelfb | Mouse | arsane | decreases methylation | ISO | NELFB (Homo sapiens) | 6480464 | Arsenic results in decreased methylation of NELFB gene | CTD | PMID:31135185 | Nelfb | Mouse | arsenic atom | affects methylation | ISO | NELFB (Homo sapiens) | 6480464 | Arsenic affects the methylation of NELFB gene | CTD | PMID:25304211 | Nelfb | Mouse | arsenic atom | decreases methylation | ISO | NELFB (Homo sapiens) | 6480464 | Arsenic results in decreased methylation of NELFB gene | CTD | PMID:31135185 | Nelfb | Mouse | arsenite(3-) | decreases expression | EXP | | 6480464 | arsenite results in decreased expression of NELFB protein | CTD | PMID:37955338 | Nelfb | Mouse | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to NELFB promoter] | CTD | PMID:19654925 | Nelfb | Mouse | bisphenol A | increases expression | ISO | Nelfb (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of NELFB mRNA | CTD | PMID:25181051 | Nelfb | Mouse | bisphenol A | multiple interactions | ISO | Nelfb (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of NELFB mRNA | CTD | PMID:36041667 | Nelfb | Mouse | bisphenol A | decreases expression | ISO | Nelfb (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of NELFB mRNA | CTD | PMID:33296240 and PMID:34947998 | Nelfb | Mouse | bisphenol A | multiple interactions | ISO | NELFB (Homo sapiens) | 6480464 | [bisphenol A binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NELFB protein modified form] | CTD | PMID:28751236 | Nelfb | Mouse | bisphenol AF | multiple interactions | ISO | NELFB (Homo sapiens) | 6480464 | [bisphenol AF binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NELFB protein modified form] and bisphenol AF inhibits the reaction [ESR1 protein binds to NELFB protein] | CTD | PMID:28751236 and PMID:29389661 | Nelfb | Mouse | bisphenol F | multiple interactions | ISO | Nelfb (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of NELFB mRNA | CTD | PMID:36041667 | Nelfb | Mouse | cadmium dichloride | decreases expression | ISO | NELFB (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of NELFB mRNA | CTD | PMID:38568856 | Nelfb | Mouse | carnosic acid | decreases expression | EXP | | 6480464 | salvin results in decreased expression of NELFB protein | CTD | PMID:35926579 | Nelfb | Mouse | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of NELFB gene | CTD | PMID:20938992 | Nelfb | Mouse | coumarin | increases phosphorylation | ISO | NELFB (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of NELFB protein | CTD | PMID:35688186 | Nelfb | Mouse | decabromodiphenyl ether | increases expression | ISO | NELFB (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of NELFB protein | CTD | PMID:31675489 | Nelfb | Mouse | Dibutyl phosphate | affects expression | ISO | NELFB (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of NELFB mRNA | CTD | PMID:37042841 | Nelfb | Mouse | doxorubicin | decreases expression | ISO | NELFB (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of NELFB mRNA | CTD | PMID:29803840 | Nelfb | Mouse | flutamide | increases expression | ISO | Nelfb (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of NELFB mRNA | CTD | PMID:24136188 | Nelfb | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | Nelfb | Mouse | FR900359 | increases phosphorylation | ISO | NELFB (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of NELFB protein | CTD | PMID:37730182 | Nelfb | Mouse | gentamycin | increases expression | ISO | Nelfb (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of NELFB mRNA | CTD | PMID:33387578 | Nelfb | Mouse | ivermectin | decreases expression | ISO | NELFB (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of NELFB protein | CTD | PMID:32959892 | Nelfb | Mouse | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of NELFB gene | CTD | PMID:20938992 | Nelfb | Mouse | nitrates | multiple interactions | EXP | | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of NELFB mRNA | CTD | PMID:35964746 | Nelfb | Mouse | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of NELFB mRNA | CTD | PMID:17562736 | Nelfb | Mouse | paracetamol | decreases expression | ISO | Nelfb (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of NELFB mRNA | CTD | PMID:33387578 | Nelfb | Mouse | SB 431542 | multiple interactions | ISO | NELFB (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of NELFB protein | CTD | PMID:37664457 | Nelfb | Mouse | tamoxifen | multiple interactions | ISO | NELFB (Homo sapiens) | 6480464 | Tamoxifen inhibits the reaction [ESR1 protein binds to NELFB protein] | CTD | PMID:23665804 | Nelfb | Mouse | titanium dioxide | decreases methylation | EXP | | 6480464 | titanium dioxide results in decreased methylation of NELFB gene | CTD | PMID:35295148 | Nelfb | Mouse | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of NELFB mRNA | CTD | PMID:33045310 | Nelfb | Mouse | valproic acid | increases methylation | ISO | NELFB (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of NELFB gene | CTD | PMID:29154799 | |