Nfu1 (NFU1 iron-sulfur cluster scaffold) - Rat Genome Database

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Gene: Nfu1 (NFU1 iron-sulfur cluster scaffold) Mus musculus
Analyze
Symbol: Nfu1
Name: NFU1 iron-sulfur cluster scaffold
RGD ID: 1317242
MGI Page MGI
Description: Predicted to enable 4 iron, 4 sulfur cluster binding activity and iron ion binding activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation by [4Fe-4S] cluster transfer. Located in mitochondrion. Is expressed in several structures, including brain; early embryo; genitourinary system; liver; and spleen. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 1. Orthologous to human NFU1 (NFU1 iron-sulfur cluster scaffold).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 0610006G17Rik; CGI-3; CGI-33; Hi; HIRA-interacting protein 5; Hirip5; histone cell cycle regulation defective interacting protein 5; mHIRIP5; NFU1 iron-sulfur cluster scaffold homolog; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm7859  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39686,986,040 - 87,005,443 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl686,986,218 - 87,005,443 (+)EnsemblGRCm39 Ensembl
GRCm38687,009,234 - 87,028,461 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,009,236 - 87,028,461 (+)EnsemblGRCm38mm10GRCm38
MGSCv37686,959,830 - 86,978,455 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36686,975,538 - 86,994,049 (+)NCBIMGSCv36mm8
Celera688,949,192 - 88,967,878 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map637.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (ISO)
mitochondrion  (HDA,IBA,ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery. Maio N and Rouault TA, Biochim Biophys Acta. 2015 Jun;1853(6):1493-512. doi: 10.1016/j.bbamcr.2014.09.009. Epub 2014 Sep 19.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11342215   PMID:12477932   PMID:12915448   PMID:14610273   PMID:15489334   PMID:16141072   PMID:16141073   PMID:18614015  
PMID:21267068   PMID:21677750   PMID:21731673   PMID:21873635   PMID:30550785  


Genomics

Comparative Map Data
Nfu1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39686,986,040 - 87,005,443 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl686,986,218 - 87,005,443 (+)EnsemblGRCm39 Ensembl
GRCm38687,009,234 - 87,028,461 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,009,236 - 87,028,461 (+)EnsemblGRCm38mm10GRCm38
MGSCv37686,959,830 - 86,978,455 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36686,975,538 - 86,994,049 (+)NCBIMGSCv36mm8
Celera688,949,192 - 88,967,878 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map637.76NCBI
NFU1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38269,395,750 - 69,439,567 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl269,396,113 - 69,437,628 (-)EnsemblGRCh38hg38GRCh38
GRCh37269,622,882 - 69,666,699 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36269,476,756 - 69,518,257 (-)NCBINCBI36Build 36hg18NCBI36
Build 34269,534,905 - 69,576,404NCBI
Celera269,473,252 - 69,514,522 (-)NCBICelera
Cytogenetic Map2p13.3NCBI
HuRef269,359,753 - 69,401,132 (-)NCBIHuRef
CHM1_1269,552,650 - 69,594,074 (-)NCBICHM1_1
T2T-CHM13v2.0269,408,096 - 69,451,867 (-)NCBIT2T-CHM13v2.0
Nfu1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84121,016,316 - 121,036,925 (+)NCBIGRCr8
mRatBN7.24119,458,981 - 119,480,162 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4119,459,061 - 119,480,373 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4124,932,395 - 124,952,928 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04120,707,135 - 120,727,667 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04119,331,386 - 119,351,919 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04118,814,284 - 118,834,955 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4118,814,284 - 118,834,955 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04183,383,769 - 183,404,239 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44121,184,017 - 121,187,110 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14121,401,604 - 121,432,159 (+)NCBI
Celera4108,428,818 - 108,449,350 (+)NCBICelera
Cytogenetic Map4q34NCBI
Nfu1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542415,647,623 - 15,674,573 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542415,648,213 - 15,671,383 (+)NCBIChiLan1.0ChiLan1.0
NFU1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21256,976,064 - 57,017,749 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A56,980,179 - 57,021,685 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A69,438,979 - 69,480,470 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A70,559,872 - 70,600,301 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A70,559,872 - 70,600,301 (-)Ensemblpanpan1.1panPan2
NFU1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11068,134,865 - 68,161,841 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1068,134,902 - 68,335,988 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1068,026,707 - 68,053,938 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01069,158,089 - 69,185,558 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1069,157,090 - 69,186,295 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11068,838,469 - 68,865,703 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01069,139,057 - 69,166,520 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01069,436,279 - 69,463,557 (-)NCBIUU_Cfam_GSD_1.0
Nfu1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629214,858,369 - 14,890,628 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649113,679,629 - 13,712,988 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649113,680,669 - 13,712,924 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFU1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl372,983,136 - 73,024,663 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1372,983,075 - 73,013,227 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2376,438,277 - 76,442,256 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NFU1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11437,690,329 - 37,731,093 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1437,690,656 - 37,730,819 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604574,263,441 - 74,305,552 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nfu1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247623,887,124 - 3,917,406 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nfu1
462 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:630
Count of miRNA genes:344
Interacting mature miRNAs:379
Transcripts:ENSMUST00000032060, ENSMUST00000117583, ENSMUST00000120240, ENSMUST00000127819, ENSMUST00000140343, ENSMUST00000144776
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671958006105958152Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67707698389976982Mouse
10412119Stv_mstriatal volumne (mouse)Not determined660026991100026967Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671958006105958152Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67797698396976961Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
12792979Fbmd2_mfemoral bone mineral density 2, females only (mouse)675026989115026943Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67552133992584431Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67552133994202936Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65842456692424693Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671552042105552160Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67129960593441074Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64529099387403016Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5435041188356155Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675424566104480516Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65851741692517416Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684099474118099474Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675584287109584431Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686783787113521563Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670402880104403016Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670402880104403016Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676440930110441074Mouse
15039373Adip28_madiposity 28 (mouse)65628519490285194Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65628519490285194Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66346172197461888Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675693484109693678Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666690851100691013Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670402880104403016Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681476981102176961Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67552133994202936Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66003466394034782Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678606487121092347Mouse

Markers in Region
UniSTS:237314  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381568,715,281 - 68,715,600UniSTSGRCm38
MGSCv371568,545,711 - 68,546,030UniSTSGRCm37
Celera1570,235,697 - 70,236,016UniSTS
Cytogenetic Map6D2UniSTS
Cytogenetic Map15D3UniSTS
AU022699  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381568,714,949 - 68,715,196UniSTSGRCm38
MGSCv371568,545,379 - 68,545,626UniSTSGRCm37
Celera1570,235,365 - 70,235,612UniSTS
Cytogenetic Map6D2UniSTS
Cytogenetic Map15D3UniSTS
cM Map1539.6UniSTS
cM Map6 UniSTS
Whitehead/MRC_RH15585.59UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001170591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_020045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006506419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006506420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC159712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ132616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY335195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD775268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000032060   ⟹   ENSMUSP00000032060
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl686,986,818 - 87,005,436 (+)Ensembl
GRCm38.p6 Ensembl687,009,836 - 87,028,454 (+)Ensembl
Ensembl Acc Id: ENSMUST00000117583   ⟹   ENSMUSP00000113332
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl686,986,818 - 87,005,441 (+)Ensembl
GRCm38.p6 Ensembl687,009,836 - 87,028,459 (+)Ensembl
Ensembl Acc Id: ENSMUST00000120240   ⟹   ENSMUSP00000113637
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl686,986,218 - 87,005,443 (+)Ensembl
GRCm38.p6 Ensembl687,009,236 - 87,028,461 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127819
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl686,986,985 - 87,002,513 (+)Ensembl
GRCm38.p6 Ensembl687,010,003 - 87,025,531 (+)Ensembl
Ensembl Acc Id: ENSMUST00000140343
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl686,986,871 - 86,990,472 (+)Ensembl
GRCm38.p6 Ensembl687,009,889 - 87,013,490 (+)Ensembl
Ensembl Acc Id: ENSMUST00000144776   ⟹   ENSMUSP00000121746
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl686,986,871 - 87,000,168 (+)Ensembl
GRCm38.p6 Ensembl687,009,889 - 87,023,186 (+)Ensembl
Ensembl Acc Id: ENSMUST00000203512
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl686,986,818 - 86,992,693 (+)Ensembl
GRCm38.p6 Ensembl687,009,836 - 87,015,711 (+)Ensembl
Ensembl Acc Id: ENSMUST00000204103
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl687,001,981 - 87,005,443 (+)Ensembl
GRCm38.p6 Ensembl687,024,999 - 87,028,461 (+)Ensembl
Ensembl Acc Id: ENSMUST00000205018
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl686,986,862 - 86,989,369 (+)Ensembl
GRCm38.p6 Ensembl687,009,880 - 87,012,387 (+)Ensembl
RefSeq Acc Id: NM_001170591   ⟹   NP_001164062
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39686,986,818 - 87,005,443 (+)NCBI
GRCm38687,009,836 - 87,028,461 (+)NCBI
MGSCv37686,959,830 - 86,978,455 (+)RGD
Celera688,949,192 - 88,967,878 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_020045   ⟹   NP_064429
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39686,986,818 - 87,005,443 (+)NCBI
GRCm38687,009,836 - 87,028,461 (+)NCBI
MGSCv37686,959,830 - 86,978,455 (+)RGD
Celera688,949,192 - 88,967,878 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006506419   ⟹   XP_006506482
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39686,986,155 - 87,005,443 (+)NCBI
GRCm38687,009,291 - 87,028,461 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006506420   ⟹   XP_006506483
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39686,986,180 - 87,005,443 (+)NCBI
GRCm38687,009,234 - 87,028,461 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152244   ⟹   XP_036008137
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39686,986,040 - 87,005,443 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152245   ⟹   XP_036008138
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39686,986,040 - 87,005,443 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152246   ⟹   XP_036008139
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39686,993,815 - 87,005,443 (+)NCBI
Sequence:
RefSeq Acc Id: NP_064429   ⟸   NM_020045
- Peptide Label: isoform 2 precursor
- UniProtKB: Q9QZ23 (UniProtKB/Swiss-Prot),   Q9D1B7 (UniProtKB/Swiss-Prot),   Q8CF80 (UniProtKB/Swiss-Prot),   Q6VNZ7 (UniProtKB/Swiss-Prot),   Q3ULE0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001164062   ⟸   NM_001170591
- Peptide Label: isoform 1 precursor
- UniProtKB: A0A0N4SUH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006506482   ⟸   XM_006506419
- Peptide Label: isoform X3
- UniProtKB: A0A0N4SUH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006506483   ⟸   XM_006506420
- Peptide Label: isoform X4
- UniProtKB: Q6VNZ7 (UniProtKB/Swiss-Prot),   Q3ULE0 (UniProtKB/Swiss-Prot),   Q9QZ23 (UniProtKB/Swiss-Prot),   Q9D1B7 (UniProtKB/Swiss-Prot),   Q8CF80 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000121746   ⟸   ENSMUST00000144776
Ensembl Acc Id: ENSMUSP00000032060   ⟸   ENSMUST00000032060
Ensembl Acc Id: ENSMUSP00000113637   ⟸   ENSMUST00000120240
Ensembl Acc Id: ENSMUSP00000113332   ⟸   ENSMUST00000117583
RefSeq Acc Id: XP_036008137   ⟸   XM_036152244
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036008138   ⟸   XM_036152245
- Peptide Label: isoform X2
RefSeq Acc Id: XP_036008139   ⟸   XM_036152246
- Peptide Label: isoform X5
Protein Domains
Scaffold protein Nfu/NifU N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QZ23-F1-model_v2 AlphaFold Q9QZ23 1-255 view protein structure

Promoters
RGD ID:6839691
Promoter ID:MM_KWN:46759
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000032060,   ENSMUST00000120240,   NM_020045,   OTTMUST00000073670,   OTTMUST00000073671,   OTTMUST00000073672
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36686,959,599 - 86,960,099 (+)MPROMDB
RGD ID:6890314
Promoter ID:EPDNEW_M8608
Type:multiple initiation site
Name:Nfu1_1
Description:Mus musculus NFU1 iron-sulfur cluster scaffold , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38687,009,886 - 87,009,946EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913290 AgrOrtholog
Ensembl Genes ENSMUSG00000029993 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032060 ENTREZGENE
  ENSMUST00000032060.15 UniProtKB/TrEMBL
  ENSMUST00000117583 ENTREZGENE
  ENSMUST00000117583.8 UniProtKB/Swiss-Prot
  ENSMUST00000120240 ENTREZGENE
  ENSMUST00000120240.8 UniProtKB/TrEMBL
  ENSMUST00000144776.7 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.300.130 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FSCA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nfu/NifU_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nfu/NifU_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NIF_FeS_clus_asmbl_NifU_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:56748 UniProtKB/Swiss-Prot
MGD MGI:1913290 ENTREZGENE
NCBI Gene Nfu1 ENTREZGENE
PANTHER IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Nfu_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NifU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nfu1 PhenoGen
SMART Nfu_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF110836 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF117916 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SUH8 ENTREZGENE, UniProtKB/TrEMBL
  D3Z285_MOUSE UniProtKB/TrEMBL
  NFU1_MOUSE UniProtKB/Swiss-Prot
  Q3ULE0 ENTREZGENE
  Q6VNZ7 ENTREZGENE
  Q8CF80 ENTREZGENE
  Q9D1B7 ENTREZGENE
  Q9QZ23 ENTREZGENE
UniProt Secondary Q3ULE0 UniProtKB/Swiss-Prot
  Q6VNZ7 UniProtKB/Swiss-Prot
  Q8CF80 UniProtKB/Swiss-Prot
  Q9D1B7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Nfu1  NFU1 iron-sulfur cluster scaffold  0610006G17Rik  RIKEN cDNA 0610006G17 gene  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 0610006G17Rik  RIKEN cDNA 0610006G17 gene  Nfu1  NFU1 iron-sulfur cluster scaffold  Symbol and/or name change 5135510 APPROVED
2016-02-29 Nfu1  NFU1 iron-sulfur cluster scaffold    NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED